A positive relationship between filamin and VEGF in patients with lung cancer

Anticancer Research

Volumn 30, Issue 10, 2010, Pages 3939-3944

  Uramoto, Hidetaka ^a   Akyurek, Levent M ^b   Hanagiri, Takeshi ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Filamin; Immunohistochemical analysis; Lung cancer; VEGF

Indexed keywords

FILAMIN A; PARAFFIN; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CANCER GROWTH; CANCER PATIENT; CANCER SURVIVAL; CONTROLLED STUDY; CYTOPLASM; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TUMOR CELL;

ADULT; AGED; AGED, 80 AND OVER; COHORT STUDIES; CONTRACTILE PROTEINS; CYTOPLASM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MICROFILAMENT PROTEINS; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; PARAFFIN EMBEDDING; RETROSPECTIVE STUDIES; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15;

EID: 78650251209     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Landis SH, Murray T, Bolden S and Wingo PA: Cancer statistics, CA. Cancer J Clin 48: 6-29, 1998.
2. Uramoto H, Sugio K, Oyama T, Nakata S, Ono K, Morita M, Funa K and Yasumoto K: Expression of deltaNp73 predicts poor prognosis in lung cancer. Clin Cancer Res 10: 6905-6911, 2004.
3. Yamashita T, Uramoto H, Onitsuka T, Ono K, Baba T, So T, So T, Takenoyama M, Hanagiri T, Oyama T and Yasumoto K: Association between lymphangiogenesis-/ micrometastasis- and adhesion-related molecules in resected stage I NSCLC. Lung Cancer in press.
4. Carmeliet P and Jain RK: Angiogenesis in cancer and other diseases. Nature 407: 249-257, 2000.
5. Stossel TP, Condeelis J, Cooley L, Hartwig JH, Noegel A, Schleicher M and Shapiro SS: Filamins as integrators of cell mechanics and signalling. Nat Rev Mol Cell Biol 2: 138-145, 2001.
6. Del Valle-Pérez B, Martínez VG, Lacasa-Salavert C, Figueras A, Shapiro SS, Takafuta T, Casanovas O, Capellà G, Ventura F and Viñals F: Filamin B plays a key role in vascular endothelial growth factor-induced endothelial cell motility through its interaction with Rac-1 and Vav-2. J Biol Chem 285: 10748-10760, 2010.
7. Kwon M, Hanna E, Lorang D, He M, Quick JS, Adem A, Stevenson C, Chung JY, Hewitt SM, Zudaire E, Esposito D, Cuttitta F and Libutti SK: Functional characterization of filamin A-interacting protein 1-like, a novel candidate for antivascular cancer therapy. Cancer Res 68: 7332-7341, 2008.
8. Mountain CF: Revisions in the International System for Staging Lung Cancer. Chest 111: 1710-1717, 1997.
9. Uramoto H, Osaki T, Inoue M, Taga S, Takenoyama M, Hanagiri T, Yoshino I, Nakanishi R, Ichiyoshi Y and Yasumoto K: Fas expression in non-small cell lung cancer: its prognostic effect in completely resected stage III patients. Eur J Cancer 35: 1462-1465, 1999.
10. Imoto H, Osaki T, Taga S, Ohgami A, Ichiyoshi Y and Yasumoto K: Vascular endothelial growth factor expression in non-small cell lung cancer: prognostic significance in squamous cell carcinoma. J Thorac Cardiovasc Surg 115: 1007-1014, 1998.
11. Uramoto H, Sugio K, Oyama T, Nakata S, Ono K, Yoshimastu T, Morita M and Yasumoto K: Expression of endoplasmic reticulum molecular chaperone GRP78 in human lung cancer and its clinical significance. Lung Cancer 49: 55-62, 2005.
12. Shieh DB, Godleski J, Herndon JE 2nd, Azuma T, Mercer H, Sugarbaker DJ and Kwiatkowski DJ: Cell motility as a prognostic factor in stage I non-small cell lung carcinoma: the role of gelsolin expression. Cancer 85: 47-57, 1999.
13. Siegel G, Malmsten M and Klussendorf D: Tumor cell locomotion and metastatic spread. Microsc Res Tech 43: 276-282, 1998.
14. Flanagan LA, Chou J, Falet H, Neujahr R, Hartwig JH and Stossel TP: Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells. J Cell Biol 155: 511-517, 2001.
15. Porter RM, Holme TC, Newman EL, Hopwood D, Wilkinson JM and Cuschieri A: Monoclonal antibodies to cytoskeletal proteins: an immunohistochemical investigation of human colon cancer. J Pathol 170: 435-440, 1993.
16. Kim H, Sengupta A, Glogauer M and McCulloch CA: Filamin A regulates cell spreading and survival via β1 integrins. Exp Cell Res 314: 834-846, 2008.
17. Nagano T, Yoneda T, Hatanaka Y, Kubota C, Murakami F and Sato M: Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone. Nat Cell Biol 4: 495-501, 2002.
18. Uramoto H, Iwata T, Onitsuka T, Shimokawa H, Hanagiri T, Oyama T and Yasumoto K: Epithelial-mesenchymal transition in EGFR-TKI-acquired resistant lung adenocarcinoma. Anticancer Res in press.
19. Keshamouni VG, Michailidis G, Grasso CS, Anthwal S, Strahler JR, Walker A, Arenberg DA, Reddy RC, Akulapalli S, Thannickal VJ, Standiford TJ, Andrews PC and Omenn GS: Differential protein expression profiling by iTRAQ-2DLC-MS/MS of lung cancer cells undergoing epithelial-mesenchymal transition reveals a migratory/invasive phenotype. J Proteome Res 5: 1143-1154, 2006.
20. Kamochi N, Nakashima M, Aoki S, Uchihashi K, Sugihara H, Toda S and Kudo S: Irradiated fibroblast-induced bystander effects on invasive growth of squamous cell carcinoma under cancer-stromal cell interaction. Cancer Sci 99: 2417-2427, 2008.
21. Loy, CJ, Sim KS and Yong EL: Filamin-A fragment localizes to the nucleus to regulate androgen receptor and coactivator functions. Proc Natl Acad Sci USA 100: 4562-4567, 2003.
22. Båtevik R, Grong K, Segadal L and Stangeland L: The female gender has a positive effect on survival independent of background life expectancy following surgical resection of primary non-small cell lung cancer: a study of absolute and relative survival over 15 years. Lung Cancer 47: 173-181, 2005.
23. Alper O, Stetler-Stevenson WG, Harris LN, Leitner WW, Ozdemirli M, Hartmann D, Raffeld M, Abu-Asab M, Byers S, Zhuang Z, Oldfield EH, Tong Y, Bergmann-Leitner E, Criss WE, Nagasaki K, Mok SC, Cramer DW, Karaveli FS, Goldbach-Mansky R, Leo P, Stromberg K and Weil RJ: Novel anti-filamin-A antibody detects a secreted variant of filamin-A in plasma from patients with breast carcinoma and high-grade astrocytoma. Cancer Sci 100: 1748-1756, 2009.
24. Sandler AB, Johnson DH and Herbst RS: Anti-vascular endothelial growth factor monoclonals in non-small cell lung cancer. Clin Cancer Res 10: 4258s-4262s, 2004.
25. Zhou AX, Toylu A, Nallapalli RK, Nilsson G, Atabey N, Heldin CH, Borén J, Bergö MO and Akyürek LM: Filamin A mediates HGF/c-MET signaling in tumor cell migration. Int J Cancer in press.
26. Onitsuka T, Uramoto H, Ono K, Takenoyama M, Hanagiri T, Oyama T, Izumi H, Kohno K and Yasumoto K: Comprehensive molecular analyses of lung adenocarcinoma with regard to the epidermal growth factor receptor, K-ras, MET, and hepatocyte growth factor status. J Thorac Oncol 5: 591-596, 2010.
27. Onitsuka T, Uramoto H, Nose N, Takenoyama M, Hanagiri T, Sugio K and Yasumoto K: Acquired resistance to gefitinib: The contribution of mechanisms other than the T790M, MET, and HGF status. Lung Cancer 68: 198-203, 2010.