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Volumn 23, Issue 2, 2012, Pages 141-146

The role of CREB-H transcription factor in triglyceride metabolism

Author keywords

apolipoprotein; CREB H; CREB3L3; transcription factor; triglyceride

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ACTIVATING TRANSCRIPTION FACTOR 6ALPHA; ACTIVATING TRANSCRIPTION FACTOR 6BETA; APOLIPOPROTEIN A4; APOLIPOPROTEIN A5; APOLIPOPROTEIN C2; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN 3L1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN 3L2; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN 3L3; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN 3L4; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN H; GLUCOCORTICOID RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84858795217     PISSN: 09579672     EISSN: 14736535     Source Type: Journal    
DOI: 10.1097/MOL.0b013e3283508fed     Document Type: Review
Times cited : (33)

References (48)
  • 1
    • 33748203658 scopus 로고    scopus 로고
    • Metabolic syndrome: Focus on dyslipidemia
    • (Silver Spring)
    • Ginsberg HN, Zhang YL, Hernandez-Ono A. Metabolic syndrome: focus on dyslipidemia. Obesity (Silver Spring) 2006; 14 (Suppl 1):41S-49S.
    • (2006) Obesity , vol.14 , Issue.SUPPL. 1
    • Ginsberg, H.N.1    Zhang, Y.L.2    Hernandez-Ono, A.3
  • 2
    • 33645863768 scopus 로고    scopus 로고
    • Transcriptional regulation of metabolism
    • Desvergne B, Michalik L, Wahli W. Transcriptional regulation of metabolism. Physiol Rev 2006; 86:465-514.
    • (2006) Physiol Rev , vol.86 , pp. 465-514
    • Desvergne, B.1    Michalik, L.2    Wahli, W.3
  • 3
    • 0026518157 scopus 로고
    • A Drosophila CREB/ATF transcriptional activator binds to both fat body-and liver-specific regulatory elements
    • Abel T, Bhatt R, Maniatis T. A Drosophila CREB/ATF transcriptional activator binds to both fat body-and liver-specific regulatory elements. Genes Dev 1992; 6:466-480.
    • (1992) Genes Dev , vol.6 , pp. 466-480
    • Abel, T.1    Bhatt, R.2    Maniatis, T.3
  • 4
    • 0026699358 scopus 로고
    • A cyclic AMP-responsive elementbinding transcriptional activator in Drosophila melanogaster, dCREB-A, is a member of the leucine zipper family
    • Smolik SM, Rose RE, Goodman RH. A cyclic AMP-responsive elementbinding transcriptional activator in Drosophila melanogaster, dCREB-A, is a member of the leucine zipper family. Mol Cell Biol 1992; 12:4123-4131.
    • (1992) Mol Cell Biol , vol.12 , pp. 4123-4131
    • Smolik, S.M.1    Rose, R.E.2    Goodman, R.H.3
  • 6
    • 54449091729 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H
    • Luebke-Wheeler J, Zhang K, Battle M, et al. Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology 2008; 48:1242-1250.
    • (2008) Hepatology , vol.48 , pp. 1242-1250
    • Luebke-Wheeler, J.1    Zhang, K.2    Battle, M.3
  • 7
    • 79960110157 scopus 로고    scopus 로고
    • The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism
    • Lee JH, Giannikopoulos P, Duncan SA, et al. The transcription factor cyclic AMP-responsive element-binding protein H regulates triglyceride metabolism. Nat Med 2011; 17:812-815.
    • (2011) Nat Med , vol.17 , pp. 812-815
    • Lee, J.H.1    Giannikopoulos, P.2    Duncan, S.A.3
  • 8
    • 35949003194 scopus 로고    scopus 로고
    • Trafficking of the bZIP transmembrane transcription factor CREB-H into alternate pathways of ERAD and stress-regulated intramembrane proteolysis
    • DOI 10.1111/j.1600-0854.2007.00654.x
    • Bailey D, Barreca C, O'Hare P. Trafficking of the bZIP transmembrane transcription factor CREB-H into alternate pathways of ERAD and stressregulated intramembrane proteolysis. Traffic 2007; 8:1796-1814. (Pubitemid 350066690)
    • (2007) Traffic , vol.8 , Issue.12 , pp. 1796-1814
    • Bailey, D.1    Barreca, C.2    O'Hare, P.3
  • 9
    • 32044453080 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
    • DOI 10.1016/j.cell.2005.11.040, PII S0092867406000043
    • Zhang K, Shen X,WuJ, et al. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell 2006; 124: 587-599. (Pubitemid 43199443)
    • (2006) Cell , vol.124 , Issue.3 , pp. 587-599
    • Zhang, K.1    Shen, X.2    Wu, J.3    Sakaki, K.4    Saunders, T.5    Rutkowski, D.T.6    Back, S.H.7    Kaufman, R.J.8
  • 10
    • 0034681260 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
    • Brown MS, Ye J, Rawson RB, Goldstein JL. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 2000; 100:391-398.
    • (2000) Cell , vol.100 , pp. 391-398
    • Brown, M.S.1    Ye, J.2    Rawson, R.B.3    Goldstein, J.L.4
  • 12
    • 68949220321 scopus 로고    scopus 로고
    • ER stress controls iron metabolism through induction of hepcidin
    • Vecchi C, Montosi G, Zhang K, et al. ER stress controls iron metabolism through induction of hepcidin. Science 2009; 325:877-880.
    • (2009) Science , vol.325 , pp. 877-880
    • Vecchi, C.1    Montosi, G.2    Zhang, K.3
  • 13
    • 77950285163 scopus 로고    scopus 로고
    • Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH
    • Lee MW, Chanda D, Yang J, et al. Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH. Cell Metab 2010; 11:331-339.
    • (2010) Cell Metab , vol.11 , pp. 331-339
    • Lee, M.W.1    Chanda, D.2    Yang, J.3
  • 14
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • DOI 10.1016/S0092-8674(00)80213-5
    • Brown MS, Goldstein JL. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 1997; 89:331-340. (Pubitemid 27220877)
    • (1997) Cell , vol.89 , Issue.3 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 15
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • DOI 10.1172/JCI200215593
    • Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 2002; 109:1125-1131. (Pubitemid 34496588)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.9 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 16
    • 50249116184 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress response in immunity and autoimmunity
    • Todd DJ, Lee AH, Glimcher LH. The endoplasmic reticulum stress response in immunity and autoimmunity. Nat Rev Immunol 2008; 8:663-674.
    • (2008) Nat Rev Immunol , vol.8 , pp. 663-674
    • Todd, D.J.1    Lee, A.H.2    Glimcher, L.H.3
  • 17
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • DOI 10.1038/nrm2199, PII NRM2199
    • Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nature Rev 2007; 8:519-529. (Pubitemid 46985379)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.7 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 18
    • 34548172495 scopus 로고    scopus 로고
    • Transcriptional Induction of Mammalian ER Quality Control Proteins Is Mediated by Single or Combined Action of ATF6α and XBP1
    • DOI 10.1016/j.devcel.2007.07.018, PII S1534580707003000
    • Yamamoto K, Sato T, Matsui T, et al. Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Dev Cell 2007; 13:365-376. (Pubitemid 47308680)
    • (2007) Developmental Cell , vol.13 , Issue.3 , pp. 365-376
    • Yamamoto, K.1    Sato, T.2    Matsui, T.3    Sato, M.4    Okada, T.5    Yoshida, H.6    Harada, A.7    Mori, K.8
  • 19
    • 35848940511 scopus 로고    scopus 로고
    • Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response
    • DOI 10.1089/ars.2007.1796
    • Bailey D, O'Hare P. Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response. Antioxid Redox Signal 2007; 9:2305-2321. (Pubitemid 350059018)
    • (2007) Antioxidants and Redox Signaling , vol.9 , Issue.12 , pp. 2305-2321
    • Bailey, D.1    O'Hare, P.2
  • 20
    • 79955424672 scopus 로고    scopus 로고
    • The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology
    • Asada R, Kanemoto S, Kondo S, et al. The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology. J Biochem 2011; 149:507-518.
    • (2011) J Biochem , vol.149 , pp. 507-518
    • Asada, R.1    Kanemoto, S.2    Kondo, S.3
  • 22
    • 33750350899 scopus 로고    scopus 로고
    • Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein herp through an ER stress response element
    • DOI 10.1128/MCB.01046-06
    • Liang G, Audas TE, Li Y, et al. Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element. Mol Cell Biol 2006; 26:7999-8010. (Pubitemid 44630999)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.21 , pp. 7999-8010
    • Liang, G.1    Audas, T.E.2    Li, Y.3    Cockram, G.P.4    Dean, J.D.5    Martyn, A.C.6    Kokame, K.7    Lu, R.8
  • 23
    • 30044441047 scopus 로고    scopus 로고
    • CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P
    • DOI 10.1091/mbc.E05-06-0500
    • Stirling J, O'Hare P. CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P. Mol Biol Cell 2006; 17:413-426. (Pubitemid 43049493)
    • (2006) Molecular Biology of the Cell , vol.17 , Issue.1 , pp. 413-426
    • Stirling, J.1    O'Hare, P.2
  • 24
    • 66349134748 scopus 로고    scopus 로고
    • Cholesterol feedback: From Schoenheimer's bottle to Scap's MELADL
    • Brown MS, Goldstein JL. Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL. J Lipid Res 2009; 50 (Suppl):S15-27.
    • (2009) J Lipid Res , vol.50 , Issue.SUPPL.
    • Brown, M.S.1    Goldstein, J.L.2
  • 25
    • 0036069980 scopus 로고    scopus 로고
    • ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of golgi localization signals
    • DOI 10.1016/S1534-5807(02)00203-4
    • Shen J, Chen X, Hendershot L, Prywes R. ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Dev Cell 2002; 3:99-111. (Pubitemid 34778399)
    • (2002) Developmental Cell , vol.3 , Issue.1 , pp. 99-111
    • Shen, J.1    Chen, X.2    Hendershot, L.3    Prywes, R.4
  • 26
    • 78149496291 scopus 로고    scopus 로고
    • HNF4alpha: Role in drug metabolism and potential drug target?
    • Hwang-Verslues WW, Sladek FM. HNF4alpha: role in drug metabolism and potential drug target? Curr Opin Pharmacol 2010; 10:698-705.
    • (2010) Curr Opin Pharmacol , vol.10 , pp. 698-705
    • Hwang-Verslues, W.W.1    Sladek, F.M.2
  • 27
    • 73449099559 scopus 로고    scopus 로고
    • The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha
    • Danno H, Ishii KA, Nakagawa Y, et al. The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha. Biochem Biophys Res Commun 2010; 391:1222-1227.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1222-1227
    • Danno, H.1    Ishii, K.A.2    Nakagawa, Y.3
  • 28
    • 34547885436 scopus 로고    scopus 로고
    • Glucocorticoids, metabolism and metabolic diseases
    • DOI 10.1016/j.mce.2007.05.015, PII S0303720707002109
    • Vegiopoulos A, Herzig S. Glucocorticoids, metabolism and metabolic diseases. Mol Cell Endocrinol 2007; 275:43-61. (Pubitemid 47259280)
    • (2007) Molecular and Cellular Endocrinology , vol.275 , Issue.1-2 , pp. 43-61
    • Vegiopoulos, A.1    Herzig, S.2
  • 30
    • 78449290358 scopus 로고    scopus 로고
    • Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin
    • Gentile CL, Wang D, Pfaffenbach KT, et al. Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin. Mol Cell Biochem 2010; 344:99-107.
    • (2010) Mol Cell Biochem , vol.344 , pp. 99-107
    • Gentile, C.L.1    Wang, D.2    Pfaffenbach, K.T.3
  • 31
    • 80051504630 scopus 로고    scopus 로고
    • Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes
    • Chanda D, Kim DK, Li T, et al. Cannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytes. J Biol Chem 2011; 286:27971-27979.
    • (2011) J Biol Chem , vol.286 , pp. 27971-27979
    • Chanda, D.1    Kim, D.K.2    Li, T.3
  • 32
    • 78751551237 scopus 로고    scopus 로고
    • Endocannabinoids in liver disease
    • Tam J, Liu J, Mukhopadhyay B, et al. Endocannabinoids in liver disease. Hepatology 2011; 53:346-355.
    • (2011) Hepatology , vol.53 , pp. 346-355
    • Tam, J.1    Liu, J.2    Mukhopadhyay, B.3
  • 33
    • 77951722696 scopus 로고    scopus 로고
    • N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H
    • Chan CP, Mak TY, Chin KT, et al. N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H. J Cell Sci 2010; 123:1438-1448.
    • (2010) J Cell Sci , vol.123 , pp. 1438-1448
    • Chan, C.P.1    Mak, T.Y.2    Chin, K.T.3
  • 34
    • 84856612360 scopus 로고    scopus 로고
    • ER-tethered transcription factor crebh regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress
    • Epub ahead of print
    • Zhang C, Wang G, Zheng Z, et al. ER-tethered transcription factor crebh regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress. Hepatology 2011. [Epub ahead of print]
    • (2011) Hepatology
    • Zhang, C.1    Wang, G.2    Zheng, Z.3
  • 35
    • 0033015655 scopus 로고    scopus 로고
    • Role of apoCs in lipoprotein metabolism: Functional differences between ApoC1, ApoC2, and ApoC3
    • Jong MC, Hofker MH, Havekes LM. Role of ApoCs in lipoprotein metabolism: functional differences between ApoC1, ApoC2, and ApoC3. Arterioscler Thromb Vasc Biol 1999; 19:472-484. (Pubitemid 29135144)
    • (1999) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.19 , Issue.3 , pp. 472-484
    • Jong, M.C.1    Hofker, M.H.2    Havekes, L.M.3
  • 38
    • 0036906508 scopus 로고    scopus 로고
    • Lipoprotein lipase: Genetics, lipid uptake, and regulation
    • DOI 10.1194/jlr.R200015-JLR200
    • Merkel M, Eckel RH, Goldberg IJ. Lipoprotein lipase: genetics, lipid uptake, and regulation. J Lipid Res 2002; 43:1997-2006. (Pubitemid 35471065)
    • (2002) Journal of Lipid Research , vol.43 , Issue.12 , pp. 1997-2006
    • Merkel, M.1    Eckel, R.H.2    Goldberg, I.J.3
  • 40
    • 74049108945 scopus 로고    scopus 로고
    • Fibroblast growth factor 21: From pharmacology to physiology
    • Kliewer SA, Mangelsdorf DJ. Fibroblast growth factor 21: from pharmacology to physiology. Am J Clin Nutr 2010; 91:254S-257S.
    • (2010) Am J Clin Nutr , vol.91
    • Kliewer, S.A.1    Mangelsdorf, D.J.2
  • 41
    • 64549137257 scopus 로고    scopus 로고
    • CIDE proteins and metabolic disorders
    • Gong J, Sun Z, Li P. CIDE proteins and metabolic disorders. Curr Opin Lipidol 2009; 20:121-126.
    • (2009) Curr Opin Lipidol , vol.20 , pp. 121-126
    • Gong, J.1    Sun, Z.2    Li, P.3
  • 42
    • 79960644031 scopus 로고    scopus 로고
    • Genetic bases of hypertriglyceridemic phenotypes
    • Johansen CT, Hegele RA. Genetic bases of hypertriglyceridemic phenotypes. Curr Opin Lipidol 2011; 22:247-253.
    • (2011) Curr Opin Lipidol , vol.22 , pp. 247-253
    • Johansen, C.T.1    Hegele, R.A.2
  • 43
    • 58549109632 scopus 로고    scopus 로고
    • Plasma lipoproteins: Genetic influences and clinical implications
    • Hegele RA. Plasma lipoproteins: genetic influences and clinical implications. Nat Rev Genet 2009; 10:109-121.
    • (2009) Nat Rev Genet , vol.10 , pp. 109-121
    • Hegele, R.A.1
  • 44
    • 84857039000 scopus 로고    scopus 로고
    • Testing for rare variant associations in complex diseases
    • Asimit J, Zeggini E. Testing for rare variant associations in complex diseases. Genome Med 2011; 3:24.
    • (2011) Genome Med , vol.3 , pp. 24
    • Asimit, J.1    Zeggini, E.2
  • 45
    • 44349132708 scopus 로고    scopus 로고
    • Common and rare variants in multifactorial susceptibility to common diseases
    • DOI 10.1038/ng.f.136, PII NGF136
    • Bodmer W, Bonilla C. Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet 2008; 40:695-701. (Pubitemid 351748875)
    • (2008) Nature Genetics , vol.40 , Issue.6 , pp. 695-701
    • Bodmer, W.1    Bonilla, C.2
  • 46
    • 84858799470 scopus 로고    scopus 로고
    • Excess of rare variants in non-GWAS candidate genes in patients with hypertriglyceridemia
    • Epub ahead of print
    • Johansen CT, Wang J, McIntyre AD, et al. Excess of rare variants in non-GWAS candidate genes in patients with hypertriglyceridemia. Circ Cardiovasc Genet 2011. [Epub ahead of print]
    • (2011) Circ Cardiovasc Genet
    • Johansen, C.T.1    Wang, J.2    McIntyre, A.D.3
  • 47
    • 0030998776 scopus 로고    scopus 로고
    • Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression
    • DOI 10.1146/annurev.biochem.66.1.581
    • Hanson RW, Reshef L. Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression. Annu Rev Biochem 1997; 66:581-611. (Pubitemid 27274668)
    • (1997) Annual Review of Biochemistry , vol.66 , pp. 581-611
    • Hanson, R.W.1    Reshef, L.2
  • 48
    • 17844395201 scopus 로고    scopus 로고
    • The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma
    • Chin KT, Zhou HJ, Wong CM, et al. The liver-enriched transcription factor CREB-H is a growth suppressor protein underexpressed in hepatocellular carcinoma. Nucleic Acids Res 2005; 33:1859-1873.
    • (2005) Nucleic Acids Res , vol.33 , pp. 1859-1873
    • Chin, K.T.1    Zhou, H.J.2    Wong, C.M.3


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