N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H

Journal of Cell Science

Volumn 123, Issue 9, 2010, Pages 1438-1448

  Chan, Chi Ping ^a   Mak, To Yuen ^a   Chin, King Tung ^a,b   Ng, Irene Oi Lin ^a   Jin, Dong Yan ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

bZIP transcription factors; CREB H; Endoplasmic reticulum; Liver enriched transcription factors; Membrane bound transcription factors; N linked glycosylation; Regulated intramembrane proteolysis; Unfolded protein response

Indexed keywords

BREFELDIN A; C REACTIVE PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN H; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE TRANSLOCATION; GLYCOSYLATION; HUMAN; HUMAN CELL; MEMBRANE BINDING; N LINKED GLYCOSYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN AGGREGATION; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

ANIMALS; BREFELDIN A; CELL LINE, TUMOR; CELL MEMBRANE; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENDOPLASMIC RETICULUM; GLYCOSYLATION; HUMANS; MICE; MUTANT PROTEINS; PROPROTEIN CONVERTASES; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN TRANSPORT; SERINE ENDOPEPTIDASES; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 77951722696     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.067819     Document Type: Article

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