CD4+ CD25+ FoxP3+ regulatory T cells suppress cytotoxicity of CD8+ effector T cells: Implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level

Journal of Neuroinflammation

Volumn 9, Issue , 2012, Pages

  Göbel, Kerstin ^a   Bittner, Stefan ^a   Melzer, Nico ^a   Pankratz, Susann ^a   Dreykluft, Angela ^a   Schuhmann, Michael K ^a   Meuth, Sven G ^a   Wiendl, Heinz ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

CD8 T effector cells; CNS parenchyma; Cytotoxicity; Neuroinflammation

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; MYELIN BASIC PROTEIN; OVALBUMIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; CASPASE 3; ENOLASE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; IL2RA PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; ORGANIC COMPOUND; OVA 8; OVA-8; PEPTIDE FRAGMENT; PKH 26;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CELL EXPANSION; CELLULAR IMMUNITY; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; EFFECTOR CELL; EX VIVO STUDY; IMMUNOSTIMULATION; IN VITRO STUDY; LYMPHOCYTE CULTURE; MOUSE; NERVE INJURY; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OLIGODENDROGLIA; PARENCHYMA; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANIMAL; BRAIN; C57BL MOUSE; CD8+ T LYMPHOCYTE; CELL CULTURE; CELL PROLIFERATION; CLASSIFICATION; CYTOLOGY; DRUG EFFECT; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; METABOLISM; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD4; BRAIN; CASPASE 3; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELIN BASIC PROTEINS; OLIGODENDROGLIA; ORGAN CULTURE TECHNIQUES; ORGANIC CHEMICALS; OVALBUMIN; PEPTIDE FRAGMENTS; PHOSPHOPYRUVATE HYDRATASE; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES, REGULATORY;

EID: 84858751200     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-9-41     Document Type: Article

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