Stereocontrolled fluorobenzylation of vinyl sulfones and α,β-unsaturated esters mediated by a remote sulfinyl group. Synthesis of functionalized enantiomerically pure benzylic fluorides

Journal of Organic Chemistry

Volumn 77, Issue 6, 2012, Pages 2893-2900

  García Ruano, José Luis ^a   Fernández Salas, José Antonio ^a   Maestro, M Carmen ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLIC; CHIRAL CENTERS; CONFIGURATIONAL STABILITY; EPIMERS; FUNCTIONALIZED; MICHAEL ACCEPTORS; ORTHO POSITION; PHENYLESTERS; SEPARABLE MIXTURES; STEREO-SELECTIVE; SULFINYL GROUP; UNSATURATED ESTERS; VINYL SULFONES;

CHEMICAL STABILITY; ESTERIFICATION; ESTERS; FLUORINE COMPOUNDS; FUNCTIONAL GROUPS; STEREOCHEMISTRY;

ENANTIOMERS;

1,2 FLUOROETHYLAMINE; ALIPHATIC AMINE; ALPHA,BETA UNSATURATED ESTER DERIVATIVE; BENZYL DERIVATIVE; ESTER DERIVATIVE; ETHYLAMINE; ETHYLENE; FLUORIDE; FLUORINE; FLUOROBENZENE; GAMMA PHENYLESTER DERIVATIVE; GAMMA PHENYLSULFONE DERIVATIVE; SULFONE DERIVATIVE; SULFOXIDE; UNCLASSIFIED DRUG; VINYL SULFONE;

ARTICLE; BENZYLATION; CHEMICAL BOND; CHEMICAL COMPOSITION; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHIRALITY; ENANTIOMER; FLUORINATION; FLUOROBENZYLATION; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS;

ESTERS; FLUORIDES; HYDROCARBONS, FLUORINATED; MOLECULAR STRUCTURE; STEREOISOMERISM; SULFONES;

EID: 84858658020     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo300174k     Document Type: Article

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