A critical view on lactose-based drug formulation and device studies for dry powder inhalation: Which are relevant and what interactions to expect?

Advanced Drug Delivery Reviews

Volumn 64, Issue 3, 2012, Pages 257-274

  De Boer, A H ^a   Chan, H K ^b   Price, R ^c  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY OF SYDNEY   (Australia)

^c University of Bath   (United Kingdom)

Author keywords

Adhesive mixtures; Carrier lactose; Dispersion; Drug formulation; Inhaler development; Powder mixing; Pulmonary drug deposition

Indexed keywords

CARRIER LACTOSE; DRUG FORMULATIONS; INHALER DEVELOPMENT; POWDER MIXING; PULMONARY DRUG;

DISPERSION (WAVES); DISPERSIONS; DRUG DOSAGE; MIXING; SUGARS; SURFACE PROPERTIES;

DRUG INTERACTIONS;

BUDESONIDE; CIPROFLOXACIN; COLISTIMETHATE; DRUG CARRIER; EXCIPIENT; INDACATEROL; LACTOSE; TOBRAMYCIN; WATER;

AIRFLOW; CHEMICAL COMPOSITION; CHEMICAL INTERACTION; COMPUTATIONAL FLUID DYNAMICS; DISPERSION; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG MIXTURE; DRY POWDER; EQUIPMENT DESIGN; INHALATION; MEDICAL RESEARCH; PARTICLE SIZE; POWDER INHALER; PRIORITY JOURNAL; REVIEW; SURFACE PROPERTY; WATER CONTENT; WETTABILITY;

CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMPOUNDING; DRY POWDER INHALERS; LACTOSE;

EID: 84858620546     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2011.04.004     Document Type: Review

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