An investigation into the relationship between carrier-based dry powder inhalation performance and formulation cohesive-adhesive force balances

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 69, Issue 2, 2008, Pages 496-507

  Jones, Matthew D ^a   Harris, Haggis ^a   Hooton, Jennifer C ^a   Shur, Jagdeep ^a   King, Graeme S ^a   Mathoulin, Camilla A ^a   Nichol, Katrina ^a   Smith, Tracey L ^a   Dawson, Michelle L ^b   Ferrie, Alan R ^b   Price, Robert ^a  

^a University of Bath   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Adhesion; Agglomerate; Atomic force microscopy; Carrier; Cohesion; Dry powder inhaler

Indexed keywords

BUDESONIDE; DRUG CARRIER; ERYTHRITOL; FLUTICASONE PROPIONATE; FORMOTEROL FUMARATE; MANNITOL; SALMETEROL XINAFOATE; TREHALOSE;

ADHESION; ARTICLE; ATOMIC FORCE MICROSCOPY; COLLOID; DRUG FORMULATION; DRY POWDER; IN VITRO STUDY; PARTICLE SIZE; PERFORMANCE;

ADHESIVENESS; ADMINISTRATION, INHALATION; ALBUTEROL; ANDROSTADIENES; ANTI-ALLERGIC AGENTS; CAPSULES; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG CARRIERS; EXCIPIENTS; LACTOSE; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POWDERS; X-RAY DIFFRACTION;

EID: 43249119443     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2007.11.019     Document Type: Article

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