The effect of carrier surface and bulk properties on drug particle detachment from crystalline lactose carrier particles during inhalation, as function of carrier payload and mixing time

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 56, Issue 2, 2003, Pages 291-302

  Dickhoff, B H J ^a,c   De Boer, A H ^a   Lambregts, D ^b   Frijlink, H W ^a  

^a Dept Pharmaceutical Technol/B ^*  (Netherlands)

^b DMV International   (Netherlands)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Adhesive mixtures; Budesonide; Bulk properties; Carrier payload; Disodium chromoglycate; Lactose; Mixing time

Indexed keywords

ADHESIVE AGENT; ALPHA LACTOSE; BUDESONIDE; CROMOGLYCATE DISODIUM; CRYSTALLIN; DRUG CARRIER; LACTOSE; LACTOSE PERMEASE;

ADHESION; ARTICLE; BULK DENSITY; COMPRESSIVE STRENGTH; CRYSTAL; DRUG MIXTURE; FLOW RATE; INHALATION; INHALER; LIPOPHILICITY; SCANNING ELECTRON MICROSCOPY; SEPARATION TECHNIQUE; SURFACE PROPERTY;

EID: 0042836858     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(03)00109-7     Document Type: Article

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