Investigations on particle surface characteristics vs. dispersion behaviour of l-leucine coated carrier-free inhalable powders

International Journal of Pharmaceutics

Volumn 385, Issue 1-2, 2010, Pages 79-85

  Raula, Janne ^a   Thielmann, Frank ^b   Naderi, Majid ^b   Lehto, Vesa Pekka ^c,e   Kauppinen, Esko I ^a,d  

^a NanoMaterials Group   (Finland)

^b Application Science   (United Kingdom)

^c UNIVERSITY OF TURKU   (Finland)

^d VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

^e UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Aerosolization; Coating; l Leucine; Pulmonary drug delivery; Surface energy; Surface modification

Indexed keywords

LEUCINE; SALBUTAMOL SULFATE;

AEROSOL; ARTICLE; CONTROLLED STUDY; DENSITY; DIFFUSION; DISPERSION; DRUG COATING; FLOW RATE; INHALATIONAL DRUG ADMINISTRATION; INVERSE GAS CHROMATOGRAPHY; MORPHOLOGY; PARTICLE SIZE; POWDER INHALER; PRIORITY JOURNAL; SIMULATOR; SURFACE PROPERTY; VAPOR;

ADMINISTRATION, INHALATION; AEROSOLS; ALBUTEROL; BRONCHODILATOR AGENTS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, GAS; DIFFUSION; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; LEUCINE; PARTICLE SIZE; POWDERS; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL;

EID: 72449183575     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.10.036     Document Type: Article

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