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Volumn 7, Issue 3, 2012, Pages

PGH 1, the precursor for the anti-inflammatory prostaglandins of the 1-series, is a potent activator of the pro-inflammatory receptor CRTH2/DP2

Author keywords

[No Author keywords available]

Indexed keywords

DIHOMO GAMMA LINOLENIC ACID; PROSTAGLANDIN D; PROSTAGLANDIN D1; PROSTAGLANDIN D2; PROSTAGLANDIN H; PROSTAGLANDIN H1; PROSTAGLANDIN H2; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PROSTAGLANDIN RECEPTOR CRTH2; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; TM 30089; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; ISOMERASE; LIPOCALIN; PROSTAGLANDIN D2 RECEPTOR; PROSTAGLANDIN R2 D ISOMERASE; PROSTAGLANDIN R2 D-ISOMERASE;

EID: 84858604184     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033329     Document Type: Article
Times cited : (13)

References (80)
  • 1
    • 0035862329 scopus 로고    scopus 로고
    • Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2
    • Hirai H, Tanaka K, Yoshie O, Ogawa K, Kenmotsu K, et al. (2001) Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2. J Exp Med 193 (2): 255-261.
    • (2001) J Exp Med , vol.193 , Issue.2 , pp. 255-261
    • Hirai, H.1    Tanaka, K.2    Yoshie, O.3    Ogawa, K.4    Kenmotsu, K.5
  • 2
    • 0035883174 scopus 로고    scopus 로고
    • Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor
    • Monneret G, Gravel S, Diamond M, Rokach J, Powell WS, (2001) Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor. Blood 98 (6): 1942-1948.
    • (2001) Blood , vol.98 , Issue.6 , pp. 1942-1948
    • Monneret, G.1    Gravel, S.2    Diamond, M.3    Rokach, J.4    Powell, W.S.5
  • 3
    • 0038138607 scopus 로고    scopus 로고
    • The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes
    • Nagata K, Hirai H, (2003) The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes. Prostaglandins Leukot Essent Fatty Acids 69 (2-3): 169-177.
    • (2003) Prostaglandins Leukot Essent Fatty Acids , vol.69 , Issue.2-3 , pp. 169-177
    • Nagata, K.1    Hirai, H.2
  • 4
    • 0042122462 scopus 로고    scopus 로고
    • A novel PGD(2) receptor expressed in eosinophils
    • Powell WS, (2003) A novel PGD(2) receptor expressed in eosinophils. Prostaglandins Leukot Essent Fatty Acids 69 (2-3): 179-185.
    • (2003) Prostaglandins Leukot Essent Fatty Acids , vol.69 , Issue.2-3 , pp. 179-185
    • Powell, W.S.1
  • 5
    • 0035216234 scopus 로고    scopus 로고
    • Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP
    • Gervais FG, Cruz RP, Chateauneuf A, Gale S, Sawyer N, et al. (2001) Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP. J Allergy Clin Immunol 108: 982-988.
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 982-988
    • Gervais, F.G.1    Cruz, R.P.2    Chateauneuf, A.3    Gale, S.4    Sawyer, N.5
  • 6
    • 22744445889 scopus 로고    scopus 로고
    • Small-molecule CRTH2 antagonists for the treatment of allergic inflammation: an overview
    • Ly TW, Bacon KB, (2005) Small-molecule CRTH2 antagonists for the treatment of allergic inflammation: an overview. Expert Opin Invest Drugs 14 (7): 769-773.
    • (2005) Expert Opin Invest Drugs , vol.14 , Issue.7 , pp. 769-773
    • Ly, T.W.1    Bacon, K.B.2
  • 7
    • 33646073728 scopus 로고    scopus 로고
    • Emerging roles of DP and CRTH2 in allergic inflammation
    • Kostenis E, Ulven T, (2006) Emerging roles of DP and CRTH2 in allergic inflammation. Trends Mol Med 12 (4): 148-158.
    • (2006) Trends Mol Med , vol.12 , Issue.4 , pp. 148-158
    • Kostenis, E.1    Ulven, T.2
  • 8
    • 33947726053 scopus 로고    scopus 로고
    • Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases
    • Pettipher R, Hansel TT, Armer R, (2007) Antagonism of the prostaglandin D2 receptors DP1 and CRTH2 as an approach to treat allergic diseases. Nat Rev Drug Discov 6 (4): 313-325.
    • (2007) Nat Rev Drug Discov , vol.6 , Issue.4 , pp. 313-325
    • Pettipher, R.1    Hansel, T.T.2    Armer, R.3
  • 9
    • 20044366174 scopus 로고    scopus 로고
    • Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor
    • Shiraishi Y, Asano K, Nakajima T, Oguma T, Suzuki Y, et al. (2005) Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor. J Pharmacol Exp Ther 312 (3): 954-960.
    • (2005) J Pharmacol Exp Ther , vol.312 , Issue.3 , pp. 954-960
    • Shiraishi, Y.1    Asano, K.2    Nakajima, T.3    Oguma, T.4    Suzuki, Y.5
  • 10
    • 69249240524 scopus 로고    scopus 로고
    • Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation
    • Uller L, Mathiesen JM, Alenmyr L, Korsgren M, Ulven T, et al. (2007) Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation. Respir Res 8: 16.
    • (2007) Respir Res , vol.8 , pp. 16
    • Uller, L.1    Mathiesen, J.M.2    Alenmyr, L.3    Korsgren, M.4    Ulven, T.5
  • 11
    • 57049141701 scopus 로고    scopus 로고
    • CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation
    • Lukacs NW, Berlin AA, Franz-Bacon K, Sasik R, Sprague LJ, et al. (2008) CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation. Am J Physiol 295 (5): L767-79.
    • (2008) Am J Physiol , vol.295 , Issue.5
    • Lukacs, N.W.1    Berlin, A.A.2    Franz-Bacon, K.3    Sasik, R.4    Sprague, L.J.5
  • 12
    • 45949101464 scopus 로고    scopus 로고
    • CRTH2 plays an essential role in the pathophysiology of Cry j 1-induced pollinosis in mice
    • Nomiya R, Okano M, Fujiwara T, Maeda M, Kimura Y, et al. (2008) CRTH2 plays an essential role in the pathophysiology of Cry j 1-induced pollinosis in mice. J Immunol 180 (8): 5680-5688.
    • (2008) J Immunol , vol.180 , Issue.8 , pp. 5680-5688
    • Nomiya, R.1    Okano, M.2    Fujiwara, T.3    Maeda, M.4    Kimura, Y.5
  • 13
    • 40449106779 scopus 로고    scopus 로고
    • Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation
    • Shiraishi Y, Asano K, Niimi K, Fukunaga K, Wakaki M, et al. (2008) Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation. J Immunol 180 (1): 541-549.
    • (2008) J Immunol , vol.180 , Issue.1 , pp. 541-549
    • Shiraishi, Y.1    Asano, K.2    Niimi, K.3    Fukunaga, K.4    Wakaki, M.5
  • 14
    • 68349137905 scopus 로고    scopus 로고
    • A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep
    • Shichijo M, Arimura A, Hirano Y, Yasui K, Suzuki N, et al. (2009) A prostaglandin D2 receptor antagonist modifies experimental asthma in sheep. Clin Exp Allergy 39 (9): 1404-1414.
    • (2009) Clin Exp Allergy , vol.39 , Issue.9 , pp. 1404-1414
    • Shichijo, M.1    Arimura, A.2    Hirano, Y.3    Yasui, K.4    Suzuki, N.5
  • 15
    • 77249086270 scopus 로고    scopus 로고
    • Pharmacological blockade of the DP2 receptor inhibits cigarette smoke-induced inflammation, mucus cell metaplasia, and epithelial hyperplasia in the mouse lung
    • Stebbins KJ, Broadhead AR, Baccei CS, Scott JM, Truong YP, et al. (2010) Pharmacological blockade of the DP2 receptor inhibits cigarette smoke-induced inflammation, mucus cell metaplasia, and epithelial hyperplasia in the mouse lung. J Pharmacol Exp Ther 332 (3): 764-775.
    • (2010) J Pharmacol Exp Ther , vol.332 , Issue.3 , pp. 764-775
    • Stebbins, K.J.1    Broadhead, A.R.2    Baccei, C.S.3    Scott, J.M.4    Truong, Y.P.5
  • 16
    • 0036533485 scopus 로고    scopus 로고
    • 15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils
    • Monneret G, Li H, Vasilescu J, Rokach J, Powell WS, (2002) 15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils. J Immunol 168 (7): 3563-3569.
    • (2002) J Immunol , vol.168 , Issue.7 , pp. 3563-3569
    • Monneret, G.1    Li, H.2    Vasilescu, J.3    Rokach, J.4    Powell, W.S.5
  • 17
    • 0036944934 scopus 로고    scopus 로고
    • Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2
    • Sawyer N, Cauchon E, Chateauneuf A, Cruz RP, Nicholson DW, et al. (2002) Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2. Br J Pharmacol 137 (8): 1163-1172.
    • (2002) Br J Pharmacol , vol.137 , Issue.8 , pp. 1163-1172
    • Sawyer, N.1    Cauchon, E.2    Chateauneuf, A.3    Cruz, R.P.4    Nicholson, D.W.5
  • 18
    • 0037407693 scopus 로고    scopus 로고
    • Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis
    • Heinemann A, Schuligoi R, Sabroe I, Hartnell A, Peskar BA, (2003) Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis. J Immunol 170 (9): 4752-4758.
    • (2003) J Immunol , vol.170 , Issue.9 , pp. 4752-4758
    • Heinemann, A.1    Schuligoi, R.2    Sabroe, I.3    Hartnell, A.4    Peskar, B.A.5
  • 19
    • 13844294096 scopus 로고    scopus 로고
    • Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes
    • Gazi L, Gyles S, Rose J, Lees S, Allan C, et al. (2005) Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes. Prostaglandins Other Lipid Mediat 75 (1-4): 153-167.
    • (2005) Prostaglandins Other Lipid Mediat , vol.75 , Issue.1-4 , pp. 153-167
    • Gazi, L.1    Gyles, S.2    Rose, J.3    Lees, S.4    Allan, C.5
  • 20
    • 30644474849 scopus 로고    scopus 로고
    • 9alpha,11beta-PGF2 and its stereoisomer PGF2alpha are novel agonists of the chemoattractant receptor, CRTH2
    • Sandig H, Andrew D, Barnes AA, Sabroe I, Pease J, (2006) 9alpha,11beta-PGF2 and its stereoisomer PGF2alpha are novel agonists of the chemoattractant receptor, CRTH2. FEBS Lett 580 (2): 373-379.
    • (2006) FEBS Lett , vol.580 , Issue.2 , pp. 373-379
    • Sandig, H.1    Andrew, D.2    Barnes, A.A.3    Sabroe, I.4    Pease, J.5
  • 21
    • 10744227854 scopus 로고    scopus 로고
    • 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils
    • Böhm E, Sturm GJ, Weiglhofer I, Sandig H, Shichijo M, et al. (2004) 11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils. J Biol Chem 279 (9): 7663-7670.
    • (2004) J Biol Chem , vol.279 , Issue.9 , pp. 7663-7670
    • Böhm, E.1    Sturm, G.J.2    Weiglhofer, I.3    Sandig, H.4    Shichijo, M.5
  • 22
    • 0015209778 scopus 로고
    • Effect of prostaglandin E 1 on adjuvant arthritis
    • Zurier RB, Quagliata F, (1971) Effect of prostaglandin E 1 on adjuvant arthritis. Nature 234 (5327): 304-305.
    • (1971) Nature , vol.234 , Issue.5327 , pp. 304-305
    • Zurier, R.B.1    Quagliata, F.2
  • 24
    • 0019950695 scopus 로고
    • Prostaglandins, immune responses, and murine lupus
    • Zurier RB, (1982) Prostaglandins, immune responses, and murine lupus. Arthritis Rheum 25 (7): 804-809.
    • (1982) Arthritis Rheum , vol.25 , Issue.7 , pp. 804-809
    • Zurier, R.B.1
  • 25
    • 0034610759 scopus 로고    scopus 로고
    • Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase
    • Rossi A, Kapahi P, Natoli G, Takahashi T, Chen Y, et al. (2000) Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature 403 (6765): 103-108.
    • (2000) Nature , vol.403 , Issue.6765 , pp. 103-108
    • Rossi, A.1    Kapahi, P.2    Natoli, G.3    Takahashi, T.4    Chen, Y.5
  • 26
    • 0346665524 scopus 로고    scopus 로고
    • Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2
    • Levin G, Duffin KL, Obukowicz MG, Hummert SL, Fujiwara H, et al. (2002) Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2. Biochem J 365 (Pt 2): 489-496.
    • (2002) Biochem J , vol.365 , Issue.Pt 2 , pp. 489-496
    • Levin, G.1    Duffin, K.L.2    Obukowicz, M.G.3    Hummert, S.L.4    Fujiwara, H.5
  • 27
    • 27744548905 scopus 로고    scopus 로고
    • Yin-yang: balancing act of prostaglandins with opposing functions to regulate inflammation
    • Mandal AK, Zhang Z, Kim SJ, Tsai PC, Mukherjee AB, (2005) Yin-yang: balancing act of prostaglandins with opposing functions to regulate inflammation. J Immunol 175 (10): 6271-6273.
    • (2005) J Immunol , vol.175 , Issue.10 , pp. 6271-6273
    • Mandal, A.K.1    Zhang, Z.2    Kim, S.J.3    Tsai, P.C.4    Mukherjee, A.B.5
  • 28
    • 67650531422 scopus 로고    scopus 로고
    • Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology
    • Buczynski MW, Dumlao DS, Dennis EA, (2009) Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology. J Lipid Res 50 (6): 1015-1038.
    • (2009) J Lipid Res , vol.50 , Issue.6 , pp. 1015-1038
    • Buczynski, M.W.1    Dumlao, D.S.2    Dennis, E.A.3
  • 29
    • 65249119361 scopus 로고    scopus 로고
    • Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation
    • Shimizu T, (2009) Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation. Annu Rev Pharmcol Toxicol 49: 123-150.
    • (2009) Annu Rev Pharmcol Toxicol , vol.49 , pp. 123-150
    • Shimizu, T.1
  • 31
    • 58149179176 scopus 로고    scopus 로고
    • Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors
    • Sturm EM, Schratl P, Schuligoi R, Konya V, Sturm GJ, et al. (2008) Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors. J Immunol 181 (10): 7273-7283.
    • (2008) J Immunol , vol.181 , Issue.10 , pp. 7273-7283
    • Sturm, E.M.1    Schratl, P.2    Schuligoi, R.3    Konya, V.4    Sturm, G.J.5
  • 32
    • 77953538471 scopus 로고    scopus 로고
    • Uptake of dihomo-gamma-linolenic acid by murine macrophages increases series-1 prostaglandin release following lipopolysaccharide treatment
    • Kakutani S, Kawashima H, Tanaka T, Shiraishi-Tateishi A, Kiso Y, (2010) Uptake of dihomo-gamma-linolenic acid by murine macrophages increases series-1 prostaglandin release following lipopolysaccharide treatment. Prostaglandins Leukot Essent Fatty Acids 83 (1): 23-29.
    • (2010) Prostaglandins Leukot Essent Fatty Acids , vol.83 , Issue.1 , pp. 23-29
    • Kakutani, S.1    Kawashima, H.2    Tanaka, T.3    Shiraishi-Tateishi, A.4    Kiso, Y.5
  • 34
    • 77956657852 scopus 로고    scopus 로고
    • Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements
    • Schröder R, Janssen N, Schmidt J, Kebig A, Merten N, et al. (2010) Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements. Nat Biotechnol 28 (9): 943-949.
    • (2010) Nat Biotechnol , vol.28 , Issue.9 , pp. 943-949
    • Schröder, R.1    Janssen, N.2    Schmidt, J.3    Kebig, A.4    Merten, N.5
  • 35
    • 80054807491 scopus 로고    scopus 로고
    • Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells
    • Schröder R, Schmidt J, Blättermann S, Peters L, Janssen N, et al. (2011) Applying label-free dynamic mass redistribution technology to frame signaling of G protein-coupled receptors noninvasively in living cells. Nat Protoc 6 (11): 1748-1760.
    • (2011) Nat Protoc , vol.6 , Issue.11 , pp. 1748-1760
    • Schröder, R.1    Schmidt, J.2    Blättermann, S.3    Peters, L.4    Janssen, N.5
  • 36
    • 13944263887 scopus 로고    scopus 로고
    • Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist
    • Ulven T, Kostenis E, (2005) Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist. J Med Chem 48 (4): 897-900.
    • (2005) J Med Chem , vol.48 , Issue.4 , pp. 897-900
    • Ulven, T.1    Kostenis, E.2
  • 37
    • 59449089513 scopus 로고    scopus 로고
    • The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation
    • Schröder R, Merten N, Mathiesen JM, Martini L, Kruljac-Letunic A, et al. (2009) The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation. J Biol Chem 284 (2): 1324-1336.
    • (2009) J Biol Chem , vol.284 , Issue.2 , pp. 1324-1336
    • Schröder, R.1    Merten, N.2    Mathiesen, J.M.3    Martini, L.4    Kruljac-Letunic, A.5
  • 38
    • 0027245830 scopus 로고
    • Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha
    • Conklin BR, Farfel Z, Lustig KD, Julius D, Bourne HR, (1993) Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha. Nature 363 (6426): 274-276.
    • (1993) Nature , vol.363 , Issue.6426 , pp. 274-276
    • Conklin, B.R.1    Farfel, Z.2    Lustig, K.D.3    Julius, D.4    Bourne, H.R.5
  • 39
    • 20144371840 scopus 로고    scopus 로고
    • A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity
    • Kostenis E, Martini L, Ellis J, Waldhoer M, Heydorn A, et al. (2005) A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity. J Pharmacol Exp Ther 313 (1): 78-87.
    • (2005) J Pharmacol Exp Ther , vol.313 , Issue.1 , pp. 78-87
    • Kostenis, E.1    Martini, L.2    Ellis, J.3    Waldhoer, M.4    Heydorn, A.5
  • 40
    • 79960732797 scopus 로고    scopus 로고
    • Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors
    • Konya V, Philipose S, Bálint Z, Olschewski A, Marsche G, et al. (2011) Interaction of eosinophils with endothelial cells is modulated by prostaglandin EP4 receptors. Eur J Immunol 41 (8): 2379-2389.
    • (2011) Eur J Immunol , vol.41 , Issue.8 , pp. 2379-2389
    • Konya, V.1    Philipose, S.2    Bálint, Z.3    Olschewski, A.4    Marsche, G.5
  • 41
    • 27644551256 scopus 로고    scopus 로고
    • 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent chemoattractant for human basophils
    • Sturm GJ, Schuligoi R, Sturm EM, Royer JF, Lang-Loidolt D, et al. (2005) 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent chemoattractant for human basophils. J Allergy Clin Immunol 116 (5): 1014-1019.
    • (2005) J Allergy Clin Immunol , vol.116 , Issue.5 , pp. 1014-1019
    • Sturm, G.J.1    Schuligoi, R.2    Sturm, E.M.3    Royer, J.F.4    Lang-Loidolt, D.5
  • 42
    • 0033105639 scopus 로고    scopus 로고
    • Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways
    • Sabroe I, Hartnell A, Jopling LA, Bel S, Ponath PD, et al. (1999) Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways. J Immunol 162 (5): 2946-2955.
    • (1999) J Immunol , vol.162 , Issue.5 , pp. 2946-2955
    • Sabroe, I.1    Hartnell, A.2    Jopling, L.A.3    Bel, S.4    Ponath, P.D.5
  • 43
    • 77951666330 scopus 로고    scopus 로고
    • Endothelium-derived prostaglandin I(2) controls the migration of eosinophils
    • Konya V, Sturm EM, Schratl P, Beubler E, Marsche G, et al. (2010) Endothelium-derived prostaglandin I(2) controls the migration of eosinophils. J Allergy Clin Immunol 125 (5): 1105-1113.
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.5 , pp. 1105-1113
    • Konya, V.1    Sturm, E.M.2    Schratl, P.3    Beubler, E.4    Marsche, G.5
  • 44
    • 80052173572 scopus 로고    scopus 로고
    • Interleukin-33 induces expression of adhesion molecules and inflammatory activation in human endothelial cells and in human atherosclerotic plaques
    • Demyanets S, Konya V, Kastl SP, Kaun C, Rauscher S, et al. (2011) Interleukin-33 induces expression of adhesion molecules and inflammatory activation in human endothelial cells and in human atherosclerotic plaques. Arterioscler Thromb Vasc Biol 31 (9): 2080-2089.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , Issue.9 , pp. 2080-2089
    • Demyanets, S.1    Konya, V.2    Kastl, S.P.3    Kaun, C.4    Rauscher, S.5
  • 45
    • 27744514582 scopus 로고    scopus 로고
    • Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells
    • Xue L, Gyles SL, Wettey FR, Gazi L, Townsend E, et al. (2005) Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells. J Immunol 175 (10): 6531-6536.
    • (2005) J Immunol , vol.175 , Issue.10 , pp. 6531-6536
    • Xue, L.1    Gyles, S.L.2    Wettey, F.R.3    Gazi, L.4    Townsend, E.5
  • 46
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling
    • Ferguson SS, (2001) Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacological reviews 53 (1): 1-24.
    • (2001) Pharmacological Reviews , vol.53 , Issue.1 , pp. 1-24
    • Ferguson, S.S.1
  • 47
    • 69249137477 scopus 로고    scopus 로고
    • Endocytosis and signalling: intertwining molecular networks
    • Sorkin A, Zastrow M von, (2009) Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol 10: 609-622.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 609-622
    • Sorkin, A.1    von Zastrow, M.2
  • 48
    • 0031446688 scopus 로고    scopus 로고
    • Intracellular trafficking of angiotensin II and its AT1 and AT2 receptors: evidence for selective sorting of receptor and ligand
    • Hein L, Meinel L, Pratt RE, Dzau VJ, Kobilka BK, (1997) Intracellular trafficking of angiotensin II and its AT1 and AT2 receptors: evidence for selective sorting of receptor and ligand. Mol Endocrinol 11 (9): 1266-1277.
    • (1997) Mol Endocrinol , vol.11 , Issue.9 , pp. 1266-1277
    • Hein, L.1    Meinel, L.2    Pratt, R.E.3    Dzau, V.J.4    Kobilka, B.K.5
  • 49
    • 0036898466 scopus 로고    scopus 로고
    • Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor
    • Whistler JL, Gerber BO, Meng EC, Baranski TJ, von Zastrow M, et al. (2002) Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor. Traffic 3 (12): 866-877.
    • (2002) Traffic , vol.3 , Issue.12 , pp. 866-877
    • Whistler, J.L.1    Gerber, B.O.2    Meng, E.C.3    Baranski, T.J.4    von Zastrow, M.5
  • 50
    • 0038121047 scopus 로고    scopus 로고
    • Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway
    • Fraile-Ramos A, Kohout TA, Waldhoer M, Marsh M, (2003) Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway. Traffic 4 (4): 243-253.
    • (2003) Traffic , vol.4 , Issue.4 , pp. 243-253
    • Fraile-Ramos, A.1    Kohout, T.A.2    Waldhoer, M.3    Marsh, M.4
  • 51
    • 0036467346 scopus 로고    scopus 로고
    • Cutting edge: agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2
    • Hirai H, Tanaka K, Takano S, Ichimasa M, Nakamura M, et al. (2002) Cutting edge: agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2. J Immunol 168 (3): 981-985.
    • (2002) J Immunol , vol.168 , Issue.3 , pp. 981-985
    • Hirai, H.1    Tanaka, K.2    Takano, S.3    Ichimasa, M.4    Nakamura, M.5
  • 52
    • 0028324572 scopus 로고
    • Effect of supplementation with 20:3(n-6), 20:4(n-6) and 20:5(n-3) on the production of prostaglandins E and F of the 1-, 2- and 3-series in turbot (Scophthalmus maximus) brain astroglial cells in primary culture
    • Bell JG, Tocher DR, Sargent JR, (1994) Effect of supplementation with 20:3(n-6), 20:4(n-6) and 20:5(n-3) on the production of prostaglandins E and F of the 1-, 2- and 3-series in turbot (Scophthalmus maximus) brain astroglial cells in primary culture. Biochim Biophys Acta 1211 (3): 335-342.
    • (1994) Biochim Biophys Acta , vol.1211 , Issue.3 , pp. 335-342
    • Bell, J.G.1    Tocher, D.R.2    Sargent, J.R.3
  • 54
    • 0035976575 scopus 로고    scopus 로고
    • Prostaglandins and leukotrienes: advances in eicosanoid biology
    • Funk CD, (2001) Prostaglandins and leukotrienes: advances in eicosanoid biology. Science 294 (5548): 1871-1875.
    • (2001) Science , vol.294 , Issue.5548 , pp. 1871-1875
    • Funk, C.D.1
  • 55
    • 4444262310 scopus 로고    scopus 로고
    • Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation
    • Hata AN, Breyer RM, (2004) Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation. Pharmacol Ther 103 (2): 147-166.
    • (2004) Pharmacol Ther , vol.103 , Issue.2 , pp. 147-166
    • Hata, A.N.1    Breyer, R.M.2
  • 56
    • 0038399865 scopus 로고    scopus 로고
    • Prevention of thrombosis and vascular inflammation: benefits and limitations of selective or combined COX-1, COX-2 and 5-LOX inhibitors
    • Gaetano G de, Donati MB, Cerletti C, (2003) Prevention of thrombosis and vascular inflammation: benefits and limitations of selective or combined COX-1, COX-2 and 5-LOX inhibitors. Trends Pharmacol Sci 24 (5): 245-252.
    • (2003) Trends Pharmacol Sci , vol.24 , Issue.5 , pp. 245-252
    • de Gaetano, G.1    Donati, M.B.2    Cerletti, C.3
  • 57
    • 0242690224 scopus 로고    scopus 로고
    • COX-2 and beyond: Approaches to prostaglandin inhibition in human disease
    • FitzGerald GA, (2003) COX-2 and beyond: Approaches to prostaglandin inhibition in human disease. Nat Rev Drug Discov 2 (11): 879-890.
    • (2003) Nat Rev Drug Discov , vol.2 , Issue.11 , pp. 879-890
    • FitzGerald, G.A.1
  • 58
    • 0037364161 scopus 로고    scopus 로고
    • The development of COX2 inhibitors
    • Flower RJ, (2003) The development of COX2 inhibitors. Nat Rev Drug Discov 2 (3): 179-191.
    • (2003) Nat Rev Drug Discov , vol.2 , Issue.3 , pp. 179-191
    • Flower, R.J.1
  • 59
    • 33644870565 scopus 로고    scopus 로고
    • COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs
    • Mitchell JA, Warner TD, (2006) COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs. Nat Rev Drug Discov 5 (1): 75-86.
    • (2006) Nat Rev Drug Discov , vol.5 , Issue.1 , pp. 75-86
    • Mitchell, J.A.1    Warner, T.D.2
  • 60
    • 66349127141 scopus 로고    scopus 로고
    • Cyclooxygenases: structural and functional insights
    • Rouzer CA, Marnett LJ, (2008) Cyclooxygenases: structural and functional insights. J Lipid Res 50 (Supplement): S29.
    • (2008) J Lipid Res , vol.50 , Issue.SUPPL.
    • Rouzer, C.A.1    Marnett, L.J.2
  • 61
    • 77951065755 scopus 로고    scopus 로고
    • Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome
    • Clarke G, Fitzgerald P, Hennessy AA, Cassidy EM, Quigley EMM, et al. (2010) Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome. J Lipid Res 51 (5): 1186-1192.
    • (2010) J Lipid Res , vol.51 , Issue.5 , pp. 1186-1192
    • Clarke, G.1    Fitzgerald, P.2    Hennessy, A.A.3    Cassidy, E.M.4    Quigley, E.M.M.5
  • 62
    • 0026611343 scopus 로고
    • Prostaglandin E1 inhibits collagenase gene expression in rabbit synoviocytes and human fibroblasts
    • Salvatori R, Guidon PT JR, Rapuano BE, Bockman RS, (1992) Prostaglandin E1 inhibits collagenase gene expression in rabbit synoviocytes and human fibroblasts. Endocrinology 131 (1): 21-28.
    • (1992) Endocrinology , vol.131 , Issue.1 , pp. 21-28
    • Salvatori, R.1    Guidon Jr., P.T.2    Rapuano, B.E.3    Bockman, R.S.4
  • 63
    • 18844467911 scopus 로고    scopus 로고
    • Cloning and crystal structure of hematopoietic prostaglandin D synthase
    • Kanaoka Y, Ago H, Inagaki E, Nanayama T, Miyano M, et al. (1997) Cloning and crystal structure of hematopoietic prostaglandin D synthase. Cell 90 (6): 1085-1095.
    • (1997) Cell , vol.90 , Issue.6 , pp. 1085-1095
    • Kanaoka, Y.1    Ago, H.2    Inagaki, E.3    Nanayama, T.4    Miyano, M.5
  • 64
    • 0034684216 scopus 로고    scopus 로고
    • Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase
    • Urade Y, Hayaishi O, (2000) Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase. Biochim Biophys Acta 1482 (1-2): 259-271.
    • (2000) Biochim Biophys Acta , vol.1482 , Issue.1-2 , pp. 259-271
    • Urade, Y.1    Hayaishi, O.2
  • 66
    • 11144355866 scopus 로고    scopus 로고
    • First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase
    • Inoue T, Okano Y, Kado Y, Aritake K, Irikura D, et al. (2004) First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase. J Biochem 135 (3): 279-283.
    • (2004) J Biochem , vol.135 , Issue.3 , pp. 279-283
    • Inoue, T.1    Okano, Y.2    Kado, Y.3    Aritake, K.4    Irikura, D.5
  • 67
    • 33744948143 scopus 로고    scopus 로고
    • Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase
    • Aritake K, Kado Y, Inoue T, Miyano M, Urade Y, (2006) Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase. J Biol Chem 281 (22): 15277-15286.
    • (2006) J Biol Chem , vol.281 , Issue.22 , pp. 15277-15286
    • Aritake, K.1    Kado, Y.2    Inoue, T.3    Miyano, M.4    Urade, Y.5
  • 68
    • 41849136839 scopus 로고    scopus 로고
    • Novel prostaglandin D synthase inhibitors generated by fragment-based drug design
    • Hohwy M, Spadola L, Lundquist B, Hawtin P, Dahmen J, et al. (2008) Novel prostaglandin D synthase inhibitors generated by fragment-based drug design. J Med Chem 51 (7): 2178-2186.
    • (2008) J Med Chem , vol.51 , Issue.7 , pp. 2178-2186
    • Hohwy, M.1    Spadola, L.2    Lundquist, B.3    Hawtin, P.4    Dahmen, J.5
  • 69
    • 65549092783 scopus 로고    scopus 로고
    • Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase
    • Irikura D, Aritake K, Nagata N, Maruyama T, Shimamoto S, et al. (2009) Biochemical, functional, and pharmacological characterization of AT-56, an orally active and selective inhibitor of lipocalin-type prostaglandin D synthase. J Biol Chem 284 (12): 7623-7630.
    • (2009) J Biol Chem , vol.284 , Issue.12 , pp. 7623-7630
    • Irikura, D.1    Aritake, K.2    Nagata, N.3    Maruyama, T.4    Shimamoto, S.5
  • 70
    • 58149236750 scopus 로고    scopus 로고
    • Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2
    • Schuligoi R, Sedej M, Waldhoer M, Vukoja A, Sturm EM, et al. (2009) Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2. J Leukoc Biol 85 (1): 136-145.
    • (2009) J Leukoc Biol , vol.85 , Issue.1 , pp. 136-145
    • Schuligoi, R.1    Sedej, M.2    Waldhoer, M.3    Vukoja, A.4    Sturm, E.M.5
  • 71
    • 53149114535 scopus 로고    scopus 로고
    • Upregulation of lipopolysaccharide-induced interleukin-10 by prostaglandin A1 in mouse peritoneal macrophages
    • Kim HY, Kim JR, Kim HS, (2008) Upregulation of lipopolysaccharide-induced interleukin-10 by prostaglandin A1 in mouse peritoneal macrophages. J Microbiol Biotechnol 18 (6): 1170-1178.
    • (2008) J Microbiol Biotechnol , vol.18 , Issue.6 , pp. 1170-1178
    • Kim, H.Y.1    Kim, J.R.2    Kim, H.S.3
  • 72
    • 49649112138 scopus 로고    scopus 로고
    • New aspect of anti-inflammatory action of lipo-prostaglandinE1 in the management of collagen diseases-related skin ulcer
    • Murota H, Kotobuki Y, Umegaki N, Tani M, Katayama I, (2008) New aspect of anti-inflammatory action of lipo-prostaglandinE1 in the management of collagen diseases-related skin ulcer. Rheumatol Int 28 (11): 1127-1135.
    • (2008) Rheumatol Int , vol.28 , Issue.11 , pp. 1127-1135
    • Murota, H.1    Kotobuki, Y.2    Umegaki, N.3    Tani, M.4    Katayama, I.5
  • 73
    • 0001295532 scopus 로고
    • Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins
    • Hamberg M, Svensson J, Samuelsson B, (1974) Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. Proc Natl Acad Sci USA 71 (10): 3824-3828.
    • (1974) Proc Natl Acad Sci USA , vol.71 , Issue.10 , pp. 3824-3828
    • Hamberg, M.1    Svensson, J.2    Samuelsson, B.3
  • 74
    • 0016684979 scopus 로고
    • Prostaglandin endoperoxides IX. Characterization of rabbit aorta contracting substance (RCS) from guinea pig lung and human platelets
    • Svensson J, Hamberg M, Samuelsson B, (1975) Prostaglandin endoperoxides IX. Characterization of rabbit aorta contracting substance (RCS) from guinea pig lung and human platelets. Acta Physiol Scan 94 (2): 222-228.
    • (1975) Acta Physiol Scan , vol.94 , Issue.2 , pp. 222-228
    • Svensson, J.1    Hamberg, M.2    Samuelsson, B.3
  • 75
    • 0345244848 scopus 로고    scopus 로고
    • Rate of vasoconstrictor prostanoids released by endothelial cells depends on cyclooxygenase-2 expression and prostaglandin I synthase activity
    • Camacho M, Lopez-Belmonte J, Vila L, (1998) Rate of vasoconstrictor prostanoids released by endothelial cells depends on cyclooxygenase-2 expression and prostaglandin I synthase activity. Circ Res 83 (4): 353-365.
    • (1998) Circ Res , vol.83 , Issue.4 , pp. 353-365
    • Camacho, M.1    Lopez-Belmonte, J.2    Vila, L.3
  • 76
    • 0035071316 scopus 로고    scopus 로고
    • Mesangial cells release untransformed prostaglandin H2 as a major prostanoid
    • Soler M, Camacho M, Sola R, Vila L, (2001) Mesangial cells release untransformed prostaglandin H2 as a major prostanoid. Kidney Int 59 (4): 1283-1289.
    • (2001) Kidney Int , vol.59 , Issue.4 , pp. 1283-1289
    • Soler, M.1    Camacho, M.2    Sola, R.3    Vila, L.4
  • 77
    • 0037466415 scopus 로고    scopus 로고
    • Endothelium-derived prostaglandin H2 evokes the stretch-induced contraction of rabbit pulmonary artery
    • Saito M, Tanabe Y, Kudo I, Nakayama K, (2003) Endothelium-derived prostaglandin H2 evokes the stretch-induced contraction of rabbit pulmonary artery. Eur J Pharmacol 467 (1-3): 151-161.
    • (2003) Eur J Pharmacol , vol.467 , Issue.1-3 , pp. 151-161
    • Saito, M.1    Tanabe, Y.2    Kudo, I.3    Nakayama, K.4
  • 78
    • 0034665271 scopus 로고    scopus 로고
    • Human vascular smooth muscle cells but not endothelial cells express prostaglandin E synthase
    • Soler M, Camacho M, Escudero JR, Iniguez MA, Vila L, (2000) Human vascular smooth muscle cells but not endothelial cells express prostaglandin E synthase. Circ Res 87 (6): 504-507.
    • (2000) Circ Res , vol.87 , Issue.6 , pp. 504-507
    • Soler, M.1    Camacho, M.2    Escudero, J.R.3    Iniguez, M.A.4    Vila, L.5
  • 79
    • 39649115638 scopus 로고    scopus 로고
    • Association of fatty acids in serum phospholipids with lung function and bronchial hyperresponsiveness in adults
    • Kompauer I, Demmelmair H, Koletzko B, Bolte G, Linseisen J, et al. (2008) Association of fatty acids in serum phospholipids with lung function and bronchial hyperresponsiveness in adults. Eur J Epidemiol 23 (3): 175-190.
    • (2008) Eur J Epidemiol , vol.23 , Issue.3 , pp. 175-190
    • Kompauer, I.1    Demmelmair, H.2    Koletzko, B.3    Bolte, G.4    Linseisen, J.5


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