A novel PGD2 receptor expressed in eosinophils

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 69, Issue 2-3, 2003, Pages 179-185

  Powell, William S ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

15 Deoxy 12,14 PGJ2; Asthma; Eicosanoids; Eosinophils; Inflammation; Receptor

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; ADENYLATE CYCLASE; ARACHIDONIC ACID; CHEMOATTRACTANT RECEPTOR; PROSTAGLANDIN D2; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ASTHMA; EOSINOPHIL; IMMUNOSTIMULATION; LUNG; MAST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVIEW; SMOOTH MUSCLE RELAXATION; TH2 CELL; THROMBOCYTE AGGREGATION;

EID: 0042122462     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-3278(03)00079-6     Document Type: Article

References (50)

1. Y. Urade, O. Hayaishi, Prostaglandin D synthase: structure and function, Vitam. Horm. 58 (2000) 89-120.
2. 2 into human airways during acute antigen challenge, N. Engl. J. Med. 315 (1986) 800-804.
3. 2 as a mediator of allergic asthma, Science 287 (2000) 2013-2017.
4. A. Arimura, K. Yasui, J. Kishino, et al., Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751, J. Pharmacol. Exp. Ther. 298 (2001) 411-419.
5. Y. Fujitani, Y. Kanaoka, K. Aritake, N. Uodome, K. Okazaki-Hatake, Y. Urade, Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice, J. Immunol. 168 (2002) 443-449.
6. X. Norel, L. Walch, C. Labat, J.P. Gascard, E. Dulmet, C. Brink, Prostanoid receptors involved in the relaxation of human bronchial preparations, Br. J. Pharmacol. 126 (1999) 867-872.
7. 2 in dogs, Prostaglandins 20 (1980) 703-715.
8. 2 in normal and asthmatic men, N. Engl. J. Med. 311 (1984) 209-213.
9. R.A. Coleman, R.L. Sheldrick, Prostanoid-induced contraction of human bronchial smooth muscle is mediated by TP-receptors, Br. J. Pharmacol. 96 (1989) 688-692.
10. M. McKenniff, I.W. Rodger, P. Norman, P.J. Gardiner, Characterisation of receptors mediating the contractile effects of prostanoids in guinea-pig and human airways, Eur. J. Pharmacol. 153 (1988) 149-159.
11. M. Abramovitz, M. Adam, Y. Boie, et al., The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs, Biochim. Biophys. Acta 1483 (2000) 285-293.
12. 2α receptor in bovine corpora lutea, Eur. J. Biochem. 56 (1975) 73-77.
13. 2) on circulating eosinophils, Prostaglandins Leukot. Med. 15 (1984) 387-397.
14. 4, J. Immunol. 150 (1993) 206-213.
15. 2 causes accumulation of eosinophils in the lumen of the dog trachea, J. Appl. Physiol. 67 (1989) 959-962.
16. 2 and histamine activate human eosinophils, J. Immunol. 148 (1992) 3536-3542.
17. H. Kita, R.I. Abu-Ghazaleh, G.J. Gleich, R.T. Abraham, Regulation of Ig-induced eosinophil degranulation by adenosine 3′,5′-cyclic monophosphate, J. Immunol. 146 (1991) 2712-2718.
18. 4) synthesis and chemotaxis of human eosinophils from normal and atopic subjects, Br. J. Pharmacol. 118 (1996) 1727-1735.
19. 2 analog ZK 118.182, Eur. J. Pharmacol. 258 (1994) 207-213.
20. 2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor, Blood 98 (2001) 1942-1948.
21. 2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2, J. Exp. Med. 193 (2001) 255-261.
22. W.S. Powell, D. Chung, S. Gravel, 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration, J. Immunol. 154 (1995) 4123-4132.
23. W.S. Powell, S. Ahmed, S. Gravel, J. Rokach, Eotaxin and RANTES enhance 5-oxo-6,8,11,14-eicosatetraenoic acid- induced eosinophil chemotaxis, J. Allergy Clin. Immunol. 107 (2001) 272-278.
24. K. Nagata, K. Tanaka, K. Ogawa, et al., Selective expression of a novel surface molecule by human Th2 cells in vivo, J. Immunol. 162 (1999) 1278-1286.
25. K. Nagata, H. Hirai, K. Tanaka, et al., CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s), FEBS Lett. 459 (1999) 195-199.
26. 2 are potent activators of human eosinophils, J. Immunol. 168 (2002) 3563-3569.
27. 2 receptors CRTH2 and DP, J. Allergy Clin. Immunol. 108 (2001) 982-988.
28. N. Sawyer, E. Cauchon, A. Chateauneuf, et al., Molecular pharmacology of the human prostaglandin D(2) receptor, CRTH2, Br. J. Pharmacol. 137 (2002) 1163-1172.
29. 2 receptor agonist in human eosinophils, J. Pharmacol. Exp. Ther. 304 (2003) 349-355.
30. 2. Identification of products formed in vitro, J. Biol. Chem. 258 (1983) 11713-11718.
31. 2 formed in human plasma, Proc. Natl. Acad. Sci. USA 81 (1984) 1317-1321.
32. 2 in human urine, J. Biol. Chem. 263 (1988) 16619-16625.
33. 2, the peroxisome proliferator-activated receptor-γ ligand, in urine, Clin. Chem. 47 (2001) 768-770.
34. D.W. Gilroy, P.R. Colville-Nash, D. Willis, J. Chivers, M.J. Paul-Clark, D.A. Willoughby, Inducible cyclooxygenase may have anti-inflammatory properties, Nat. Med. 5 (1999) 698-701.
35. 2 metabolite generated during inflammatory processes, J. Biol. Chem. 277 (2002) 10459-10466.
36. 2: the endogenous electrophile that induces neuronal apoptosis, Proc. Natl. Acad. Sci. USA 99 (2002) 7367-7372.
37. 2 on malignant cells, Prostaglandins Other Lipid. Mediat. 62 (2000) 75-90.
38. 2 is a ligand for the adipocyte determination factor PPAR-γ, Cell 83 (1995) 803-812.
39. 2 metabolite binds peroxisome proliferator-activated receptor-γ and promotes adipocyte differentiation, Cell 83 (1995) 813-819.
40. M. Ricote, A.C. Li, T.M. Willson, C.J. Kelly, C.K. Glass, The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation, Nature 391 (1998) 79-82.
41. A. Rossi, P. Kapahi, G. Natoli, T. Takahashi, Y. Chen, M. Karin, M.G. Santoro, Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase, Nature 403 (2000) 103-108.
42. 2 inhibits multiple steps in the NF-κB signaling pathway, Proc. Natl. Acad. Sci. USA 97 (2000) 4844-4849.
43. C. Jiang, A.T. Ting, B. Seed, PPAR-γ agonists inhibit production of monocyte inflammatory cytokines, Nature 391 (1998) 82-86.
44. R.B. Clark, D. Bishop-Bailey, T. Estrada-Hernandez, T. Hla, L. Puddington, S.J. Padula, The nuclear receptor PPAR-γ and immunoregulation: PPAR-γ mediates inhibition of helper T cell responses, J. Immunol. 164 (2000) 1364-1371.
45. H. Inoue, T. Tanabe, K. Umesono, Feedback control of cyclooxygenase-2 expression through PPAR-γ, J. Biol. Chem. 275 (2000) 28028-28032.
46. 2 induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats, J. Clin. Invest. 106 (2000) 189-197.
47. F. Bureau, C. Desmet, D. Melotte, et al., P. A proinflammatory role for the cyclopentenone prostaglandins at low micromolar concentrations: oxidative stress-induced extracellular signal-regulated kinase activation without NF-κB inhibition, J. Immunol. 168 (2002) 5318-5325.
48. 2, J. Immunol. 166 (2001) 7104-7111.
49. 2 receptor, CRTH2, J. Immunol. 168 (2002) 981-985.
50. 2-like and eotaxin-like selective responses in eosinophils and basophils, J. Biol. Chem. 277 (2002) 26012-26020.