Integrated quantitative and qualitative workflow for in vivo bioanalytical support in drug discovery using hybrid Q-TOF-MS

Bioanalysis

Volumn 4, Issue 5, 2012, Pages 511-528

  Ranasinghe, Asoka ^a   Ramanathan, Ragu ^a   Jemal, Mohammed ^a   D'arienzo, Celia J ^a   Humphreys, W Griffith ^a   Olah, Timothy V ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3' HYDROXY BUSPIRONE; 6' HYDROXY BUSPIRONE; BUSPIRONE; BUSPIRONE N OXIDE; CAFFEINE; CHYMOTRYPSIN; DICLOFENAC; DICLOFENAC ACYL GLUCURONIDE; ENDOTHELIN 3; GLUCURONIDE; KETOCONAZOLE; OXIDE; PEPSIN A; PEPTIDE; PEPTIDE 1; RESERPINE; TRYPSIN; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; DRUG RESEARCH; DRUG STRUCTURE; ELECTROSPRAY; IN VIVO STUDY; LIMIT OF QUANTITATION; MASS SPECTROMETER; METABOLITE; MOLECULAR WEIGHT; NONHUMAN; PEPTIDE ANALYSIS; PROCESS DEVELOPMENT; PROTEIN CLEAVAGE; QUADRUPOLE MASS SPECTROMETRY; RAT; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

CAFFEINE; DRUG DISCOVERY; MASS SPECTROMETRY; PEPTIDES; SMALL MOLECULE LIBRARIES; SOFTWARE;

EID: 84858391327     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.13     Document Type: Article

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