LC-MS/MS-based approach for obtaining exposure estimates of metabolites in early clinical trials using radioactive metabolites as reference standards.

Drug metabolism letters

Volumn 1, Issue 4, 2007, Pages 293-298

  Zhang, Donglu ^a   Raghavan, Nirmala ^a   Chando, Theodore ^a   Gambardella, Janice ^a   Fu, Yunlin ^a   Zhang, Duxi ^a   Unger, Steve E ^a   Humphreys, W Griffith ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; GLUCURONIDE; RADIOISOTOPE;

ANIMAL; ARTICLE; DOG; HUMAN; LIQUID CHROMATOGRAPHY; METABOLISM; METHODOLOGY; PHASE 1 CLINICAL TRIAL; STANDARD; TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, LIQUID; CLINICAL TRIALS, PHASE I AS TOPIC; DOGS; GLUCURONIDES; HUMANS; PHARMACEUTICAL PREPARATIONS; RADIOISOTOPES; REFERENCE STANDARDS; TANDEM MASS SPECTROMETRY;

EID: 65249125136     PISSN: 18723128     EISSN: None     Source Type: Journal    
DOI: 10.2174/187231207783221411     Document Type: Article

References (0)