Full-scan high resolution accurate mass spectrometry (HRMS) in regulated bioanalysis: LC-HRMS for the quantitation of prednisone and prednisolone in human plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 879, Issue 27, 2011, Pages 2919-2927

  Fung, Eliza N ^a   Xia, Yuan Qing ^a,b   Aubry, Anne Francoise ^a   Zeng, Jianing ^a   Olah, Timothy ^a   Jemal, Mohammed ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b MDS SCIEX   (Canada)

Author keywords

High resolution accurate mass spectrometry; LC HRMS; LC MS MS; Prednisone and prednisolone; Regulated bioanalysis

Indexed keywords

ANALYTES; BIOANALYSIS; EXTRACTED ION CHROMATOGRAM; HIGH RESOLUTION; HUMAN PLASMAS; LC-HRMS; LC-MS/MS; LIQUID-LIQUID EXTRACTION PROCEDURE; LOWER LIMIT OF QUANTITATIONS; MATRIX EFFECTS; PLASMA SAMPLES; PREDNISOLONE; QUADRUPOLES; QUALITATIVE INFORMATION; SCAN DATA; TIME-OF-FLIGHT MASS SPECTROMETERS;

CHROMATOGRAPHIC ANALYSIS; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; PHOSPHOLIPIDS; PLASMA (HUMAN); PLASMAS;

SOLVENT EXTRACTION;

CORTISONE; HYDROCORTISONE; PHOSPHOLIPID; PREDNISOLONE; PREDNISONE;

ARTICLE; CALIBRATION; DRUG BLOOD LEVEL; DRUG STRUCTURE; HIGH RESOLUTION ACCURATE MASS SPECTROMETRY; HUMAN; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUADRUPOLE MASS SPECTROMETRY; QUANTITATIVE ANALYSIS;

CHROMATOGRAPHY, LIQUID; DATA MINING; HUMANS; LEAST-SQUARES ANALYSIS; MASS SPECTROMETRY; PREDNISOLONE; PREDNISONE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 80052938446     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.08.025     Document Type: Article

References (33)

1. Jemal M. Biomed. Chromatogr. 2000, 14:422.
2. Maurer H.H. Clin. Biochem. 2005, 38:310.
3. Xu R.N., Fana L., Riesera M.J., El-Shourbagya T.A. J. Pharm. Biomed. Anal. 2007, 44:342.
4. Korfmacher W.A. Drug Discov. Today 2005, 10:1357.
5. Zhou S., Song Q., Tang Y., Weng N. Curr. Pharmaceut. Anal. 2005, 1:3.
6. Srinivas N.R., Mullangi R. Biomed. Chromatogr. 2011, 25:65.
7. Chu I., Nomeir A.A. Curr. Drug Metab. 2006, 7:467.
8. Van Eeckhaut A., Lanckmans K., Sarre S., Smolders I., Michotte Y. J. Chromatogr. B 2009, 877:2198.
9. Jemal M., Ouyang Z., Xia Y. Biomed. Chromatogr. 2010, 24:2.
10. Ma S., Zhu M. Chem. Biol. Interact. 2009, 179:25.
11. Zhu M., Ma L., Zhang D., Ray K., Zhao W., Humphreys W.G., Skiles G., Sanders M., Zhang H. Drug Metab. Dispos. 2006, 34:1722.
12. Zhu M., Ma L., Zhang H., Humphreys W.G. Anal. Chem. 2007, 79:8333.
13. Maurer H.H. Ther. Drug Monit. 2010, 32:324.
14. Zhang H., Zhang D., Ray K., Zhu M. J. Mass Spectrom. 2009, 44:999.
15. Zhang N.R., Yu S., Tiller P., Yeh S., Mahan E., Emary W.B. Rapid Commun. Mass Spectrom. 2009, 23:1085.
16. Nielen M.W.F., van Engelen M.C., Zuiderent R., Ramaker R. Anal. Chim. Acta 2007, 586:122.
17. Kaufmann A., Butcher P., Maden K., Walker S., Widmer M. Anal. Chim. Acta 2010, 673:60.
18. Xia Y., Lau J., Olah T., Jemal M. Rapid Commun. Mass Spectrom. 2011, 25:2863-2878.
19. Kellmann M., Muenster H., Zomer P., Mol H. J. Am. Soc. Mass Spectrom. 2009, 20:1464.
20. Bateman K.P., Kellmann M., Muenster H., Papp R., Taylor L. J. Am. Soc. Mass Spectrom. 2009, 20:1441.
21. Rousu T., Herttuainen J., Tolonen A. Rapid Commun. Mass Spectrom. 2010, 24:939.
22. Zhang T., Watson D.G., Azike C., Tettey J.N., Stearns A.T., Binning A.R., Payne C.J. J. Chromatogr. B 2007, 857:352.
23. FDA, Guidance for Industry: Bioanalytical Method Validation, 2001.
24. Jenkins J.S., Sampson P.A. Br. Med. J. 1967, 2:205.
25. Earla R., Boddu S.H., Cholkar K., Hariharan S., Jwala J., Mitra A.K. J. Pharm. Biomed. Anal. 2010, 52:525.
26. DiFrancescoa R., Frerichsa V., Donnellya J., Haglera C., Hochreitera J., Tornatore K.M. J. Chromatogr. B 2007, 859:42.
27. Ionita I.A., Fast D.M., Akhlaghi F. J. Chromatogr. B 2009, 877:765.
28. Garga V., Jusko W.J. J. Chromatogr. 1991, 567:39.
29. Teng R.L., Benet L.Z. J. Chromatogr. 1989, 493:421.
30. Cannell G.R., Mortimer R.H., Maguire D.J., Addison R.S. J. Chromatogr. 1991, 563:341.
31. Ionita I.A., Akhlaghi F. Ann. Clin. Biochem. 2010, 47:350.
32. Rose J.Q., Yurchak A.M., Jusko W.J. Biopharm. Drug Dispos. 1980, 1:247.
33. Xia Y., Jemal M. Rapid Commun. Mass Spectrom. 2009, 23:2125.