Ultra-low flow nanospray for the normalization of conventional liquid chromatography/mass spectrometry through equimolar response: Standard-free quantitative estimation of metabolite levels in drug discovery

Rapid Communications in Mass Spectrometry

Volumn 20, Issue 7, 2006, Pages 1087-1096

  Valaskovic, Gary A ^a   Utley, Lucas ^b   Lee, Mike S ^c   Wu, Jing Tao ^b  

^a New Objective Inc ^*  (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c Milestone Development Services   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; DRUG PRODUCTS; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

DRUG DISCOVERY; DRUG METABOLITES; DRUG MOLECULES; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; LOW FLOW; METABOLITE LEVEL; NANOSPRAY; NORMALISATION; QUANTITATIVE ESTIMATION; REFERENCE STANDARD;

METABOLITES;

EID: 33645533680     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.2414     Document Type: Article

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