Accurate-mass instrumentation should not always be the first-and-only choice for MS in the drug metabolism environment

Bioanalysis

Volumn 3, Issue 16, 2011, Pages 1795-1798

  Weston, Daniel J ^a   Beattie, Iain G ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

accurate mass; alternatives; drug metabolism; metabolite characterization; metabolites in safety testing (MIST); MS

Indexed keywords

DRUG METABOLITE;

DRUG DEVELOPMENT; DRUG INDUSTRY; DRUG METABOLISM; DRUG SCREENING; DRUG TRANSFORMATION; ELUTION; INSTRUMENTATION; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; MASS SPECTROMETRY; PHARMACOKINETICS; PROCESS OPTIMIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; REVIEW; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; WORKFLOW;

CHROMATOGRAPHY, LIQUID; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HUMANS; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS;

EID: 80052505619     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.11.169     Document Type: Review

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