-
1
-
-
80051580618
-
Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
-
Siegel, R., Ward, E., Brawley, O. & Jemal, A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J. Clin. 61, 212-236 (2011).
-
(2011)
CA Cancer J. Clin.
, vol.61
, pp. 212-236
-
-
Siegel, R.1
Ward, E.2
Brawley, O.3
Jemal, A.4
-
2
-
-
0036086280
-
Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: A gene expression analysis on total and microdissected prostate tissue
-
Ernst, T. et al. Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: a gene expression analysis on total and microdissected prostate tissue. Am. J. Pathol. 160, 2169-2180 (2002). (Pubitemid 34663408)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.6
, pp. 2169-2180
-
-
Ernst, T.1
Hergenhahn, M.2
Kenzelmann, M.3
Cohen, C.D.4
Bonrouhi, M.5
Weninger, A.6
Klaren, R.7
Grone, E.F.8
Wiesel, M.9
Gudemann, C.10
Kuster, J.11
Schott, W.12
Staehler, G.13
Kretzler, M.14
Hollstein, M.15
Grone, H.-J.16
-
3
-
-
0043244946
-
Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression
-
Vanaja, D. K., Cheville, J. C., Iturria, S. J. & Young, C. Y. Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression. Cancer Res. 63, 3877-3882 (2003). (Pubitemid 36917897)
-
(2003)
Cancer Research
, vol.63
, Issue.14
, pp. 3877-3882
-
-
Vanaja, D.K.1
Cheville, J.C.2
Iturria, S.J.3
Young, C.Y.F.4
-
4
-
-
20444493600
-
Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome
-
DOI 10.1038/sj.onc.1208518
-
Petrovics, G. et al. Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome. Oncogene 24, 3847-3852 (2005). (Pubitemid 40826884)
-
(2005)
Oncogene
, vol.24
, Issue.23
, pp. 3847-3852
-
-
Petrovics, G.1
Liu, A.2
Shaheduzzaman, S.3
Furasato, B.4
Sun, C.5
Chen, Y.6
Nau, M.7
Ravindranath, L.8
Chen, Y.9
Dobi, A.10
Srikantan, V.11
Sesterhenn, I.A.12
McLeod, D.G.13
Vahey, M.14
Moul, J.W.15
Srivastava, S.16
-
5
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
DOI 10.1126/science.1117679
-
Tomlins, S. A. et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310, 644-648 (2005). (Pubitemid 41528150)
-
(2005)
Science
, vol.310
, Issue.5748
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.-W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
6
-
-
34547642493
-
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
-
DOI 10.1038/nature06024, PII NATURE06024
-
Tomlins, S. A. et al. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature 448, 595-599 (2007). (Pubitemid 47206938)
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 595-599
-
-
Tomlins, S.A.1
Laxman, B.2
Dhanasekaran, S.M.3
Helgeson, B.E.4
Cao, X.5
Morris, D.S.6
Menon, A.7
Jing, X.8
Cao, Q.9
Han, B.10
Yu, J.11
Wang, L.12
Montie, J.E.13
Rubin, M.A.14
Pienta, K.J.15
Roulston, D.16
Shah, R.B.17
Varambally, S.18
Mehra, R.19
Chinnaiyan, A.M.20
more..
-
7
-
-
45849103492
-
Recurrent gene fusions in prostate cancer
-
Kumar-Sinha, C., Tomlins, S. A. & Chinnaiyan, A. M. Recurrent gene fusions in prostate cancer. Nat. Rev. Cancer 8, 497-511 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 497-511
-
-
Kumar-Sinha, C.1
Tomlins, S.A.2
Chinnaiyan, A.M.3
-
8
-
-
67650489112
-
N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer
-
Pflueger, D. et al. N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer. Neoplasia 11, 804-811 (2009).
-
(2009)
Neoplasia
, vol.11
, pp. 804-811
-
-
Pflueger, D.1
-
9
-
-
84860128746
-
Oncogenic activation of ERG: A predominant mechanism in prostate cancer
-
Sreenath, T., Dobi, A., Petrovics, G. & Srivastava, S. Oncogenic activation of ERG: a predominant mechanism in prostate cancer. J. Carcinog. http://dx.doi.org/10.4103/1477-316391122.
-
J. Carcinog.
-
-
Sreenath, T.1
Dobi, A.2
Petrovics, G.3
Srivastava, S.4
-
10
-
-
80053078529
-
Common gene rearrangements in prostate cancer
-
Rubin, M. A., Maher, C. A. & Chinnaiyan, A. M. Common gene rearrangements in prostate cancer. J. Clin. Oncol. 29, 3659-3668 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 3659-3668
-
-
Rubin, M.A.1
Maher, C.A.2
Chinnaiyan, A.M.3
-
11
-
-
70350109641
-
ETS gene fusions in prostate cancer
-
Clark, J. P. & Cooper, C. S. ETS gene fusions in prostate cancer. Nat. Rev. Urol. 6, 429-439 (2009).
-
(2009)
Nat. Rev. Urol.
, vol.6
, pp. 429-439
-
-
Clark, J.P.1
Cooper, C.S.2
-
12
-
-
51449107401
-
Fusion in the ETS gene family and prostate cancer
-
Narod, S. A., Seth, A. & Nam, R. Fusion in the ETS gene family and prostate cancer. Br. J. Cancer 99, 847-851 (2008).
-
(2008)
Br. J. Cancer
, vol.99
, pp. 847-851
-
-
Narod, S.A.1
Seth, A.2
Nam, R.3
-
13
-
-
39049150843
-
Role of the TMPRSS2-ERG gene fusion in prostate cancer
-
DOI 10.1593/neo.07822
-
Tomlins, S. A. et al. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 10, 177-188 (2008). (Pubitemid 351240884)
-
(2008)
Neoplasia
, vol.10
, Issue.2
, pp. 177-188
-
-
Tomlins, S.A.1
Laxman, B.2
Varambally, S.3
Cao, X.4
Yu, J.5
Helgeson, B.E.6
Cao, Q.7
Prensner, J.R.8
Rubin, M.A.9
Shah, R.B.10
Mehra, R.11
Chinnaiyan, A.M.12
-
14
-
-
41149097040
-
A causal role for ERG in neoplastic transformation of prostate epithelium
-
DOI 10.1073/pnas.0711711105
-
Klezovitch, O. et al. A causal role for ERG in neoplastic transformation of prostate epithelium. Proc. Natl Acad. Sci. USA 105, 2105-2110 (2008). (Pubitemid 351439472)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.6
, pp. 2105-2110
-
-
Klezovitch, O.1
Risk, M.2
Coleman, I.3
Lucas, J.M.4
Null, M.5
True, L.D.6
Nelson, P.S.7
Vasioukhin, V.8
-
15
-
-
66749100105
-
Cooperativity of tmprss2-erg with pi3-kinase pathway activation in prostate oncogenesis
-
King, J. C. et al. Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis. Nat. Genet. 41, 524-526 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 524-526
-
-
King, J.C.1
-
16
-
-
66749188650
-
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
-
Carver, B. S. et al. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat. Genet. 41, 619-624 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 619-624
-
-
Carver, B.S.1
-
17
-
-
68149159298
-
ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells
-
Zong, Y. et al. ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells. Proc. Natl Acad. Sci. USA 106, 12465-12470 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 12465-12470
-
-
Zong, Y.1
-
18
-
-
51649115957
-
TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation
-
Sun, C. et al. TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation. Oncogene 27, 5348-5353 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 5348-5353
-
-
Sun, C.1
-
19
-
-
79955968629
-
Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer
-
Brenner, J. C. et al. Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer. Cancer Cell 19, 664-678 (2011).
-
(2011)
Cancer Cell
, vol.19
, pp. 664-678
-
-
Brenner, J.C.1
-
20
-
-
77956285565
-
ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer
-
Kunderfranco, P. et al. ETS transcription factors control transcription of EZH2 and epigenetic silencing of the tumor suppressor gene Nkx3.1 in prostate cancer. PLoS ONE 5, e10547 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Kunderfranco, P.1
-
21
-
-
77952103123
-
An integrated network of androgen receptor, polycomb, and tmprss2-erg gene fusions in prostate cancer progression
-
Yu, J. et al. An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell 17, 443-454 (2010).
-
(2010)
Cancer Cell
, vol.17
, pp. 443-454
-
-
Yu, J.1
-
22
-
-
79951838697
-
ERG oncogene modulates prostaglandin signaling in prostate cancer cells
-
Mohamed, A. A. et al. ERG oncogene modulates prostaglandin signaling in prostate cancer cells. Cancer Biol. Ther. 11, 410-417 (2011).
-
(2011)
Cancer Biol. Ther.
, vol.11
, pp. 410-417
-
-
Mohamed, A.A.1
-
23
-
-
79951841313
-
Activation of nf-{kappa}b by tmprss2/erg fusion isoforms through toll-like receptor-4
-
Wang, J. et al. Activation of NF-{kappa}B by TMPRSS2/ERG fusion isoforms through Toll-like receptor-4. Cancer Res. 71, 1325-1333 (2011).
-
(2011)
Cancer Res
, vol.71
, pp. 1325-1333
-
-
Wang, J.1
-
24
-
-
79959829839
-
Tmprss2/erg promotes epithelial to mesenchymal transition through the zeb1/zeb2 axis in a prostate cancer model
-
Leshem, O. et al. TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model. PLoS ONE 6, e21650 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Leshem, O.1
-
25
-
-
50349102353
-
TMPRSS2:ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis
-
Saramaki, O. R. et al. TMPRSS2:ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis. Clin. Cancer Res. 14, 3395-3400 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3395-3400
-
-
Saramaki, O.R.1
-
26
-
-
34547626674
-
Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer
-
Winnes, M., Lissbrant, E., Damber, J. E. & Stenman, G. Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer. Oncol. Rep. 17, 1033-1036 (2007).
-
(2007)
Oncol. Rep.
, vol.17
, pp. 1033-1036
-
-
Winnes, M.1
Lissbrant, E.2
Damber, J.E.3
Stenman, G.4
-
27
-
-
60549107254
-
Tmprss2-erg gene fusion is not associated with outcome in patients treated by prostatectomy
-
Gopalan, A. et al. TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. Cancer Res. 69, 1400-1406 (2009).
-
(2009)
Cancer Res
, vol.69
, pp. 1400-1406
-
-
Gopalan, A.1
-
28
-
-
78249235620
-
ERG expression levels in prostate tumors reflect functional status of the androgen receptor (AR) as a consequence of fusion of ERG with AR regulated gene promoters
-
Dobi, A. et al. ERG expression levels in prostate tumors reflect functional status of the androgen receptor (AR) as a consequence of fusion of ERG with AR regulated gene promoters. The Open Cancer Journal 3, 101-108 (2010).
-
(2010)
The Open Cancer Journal
, vol.3
, pp. 101-108
-
-
Dobi, A.1
-
29
-
-
33845329915
-
TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer
-
DOI 10.1158/0008-5472.CAN-06-1871
-
Hermans, K. G. et al. TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer. Cancer Res. 66, 10658-10663 (2006). (Pubitemid 44876959)
-
(2006)
Cancer Research
, vol.66
, Issue.22
, pp. 10658-10663
-
-
Hermans, K.G.1
Van Marion, R.2
Van Dekken, H.3
Jenster, G.4
Van Weerden, W.M.5
Trapman, J.6
-
30
-
-
33845884027
-
Integrative molecular concept modeling of prostate cancer progression
-
DOI 10.1038/ng1935, PII NG1935
-
Tomlins, S. A. et al. Integrative molecular concept modeling of prostate cancer progression. Nat. Genet. 39, 41-51 (2007). (Pubitemid 46026500)
-
(2007)
Nature Genetics
, vol.39
, Issue.1
, pp. 41-51
-
-
Tomlins, S.A.1
Mehra, R.2
Rhodes, D.R.3
Cao, X.4
Wang, L.5
Dhanasekaran, S.M.6
Kalyana-Sundaram, S.7
Wei, J.T.8
Rubin, M.A.9
Pienta, K.J.10
Shah, R.B.11
Chinnaiyan, A.M.12
-
31
-
-
37049015104
-
Expression of the TMPRSS2: ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer
-
DOI 10.1038/sj.bjc.6604054, PII 6604054
-
Nam, R. K. et al. Expression of the TMPRSS2:ERG fusion gene predicts cancer recurrence after surgery for localised prostate cancer. Br. J. Cancer 97, 1690-1695 (2007). (Pubitemid 350249347)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.12
, pp. 1690-1695
-
-
Nam, R.K.1
Sugar, L.2
Yang, W.3
Srivastava, S.4
Klotz, L.H.5
Yang, L.-Y.6
Stanimirovic, A.7
Encioiu, E.8
Neill, M.9
Loblaw, D.A.10
Trachtenberg, J.11
Narod, S.A.12
Seth, A.13
-
32
-
-
34248510706
-
TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort
-
DOI 10.1038/sj.onc.1210237, PII 1210237
-
Demichelis, F. et al. TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort. Oncogene 26, 4596-4599 (2007). (Pubitemid 47037039)
-
(2007)
Oncogene
, vol.26
, Issue.31
, pp. 4596-4599
-
-
Demichelis, F.1
Fall, K.2
Perner, S.3
Andren, O.4
Schmidt, F.5
Setlur, S.R.6
Hoshida, Y.7
Mosquera, J.-M.8
Pawitan, Y.9
Lee, C.10
Adami, H.-O.11
Mucci, L.A.12
Kantoff, P.W.13
Andersson, S.-O.14
Chinnaiyan, A.M.15
Johansson, J.-E.16
Rubin, M.A.17
-
33
-
-
33749029695
-
TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer
-
DOI 10.1158/0008-5472.CAN-06-1482
-
Perner, S. et al. TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer. Cancer Res. 66, 8337-8341 (2006). (Pubitemid 44449140)
-
(2006)
Cancer Research
, vol.66
, Issue.17
, pp. 8337-8341
-
-
Perner, S.1
Demichelis, F.2
Beroukhim, R.3
Schmidt, F.H.4
Mosquera, J.-M.5
Setlur, S.6
Tchinda, J.7
Tomlins, S.A.8
Hofer, M.D.9
Pienta, K.G.10
Kuefer, R.11
Vessella, R.12
Sun, X.-W.13
Meyerson, M.14
Lee, C.15
Sellers, W.R.16
Chinnaiyan, A.M.17
Rubin, M.A.18
-
34
-
-
33749034498
-
Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer
-
DOI 10.1158/0008-5472.CAN-06-1966
-
Wang, J., Cai, Y., Ren, C. & Ittmann, M. Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer. Cancer Res. 66, 8347-8351 (2006). (Pubitemid 44449142)
-
(2006)
Cancer Research
, vol.66
, Issue.17
, pp. 8347-8351
-
-
Wang, J.1
Cai, Y.2
Ren, C.3
Ittmann, M.4
-
35
-
-
33947590808
-
Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers
-
DOI 10.1136/jcp.2006.043810
-
Rajput, A. B. et al. Frequency of the TMPRSS2:ERG gene fusion is increased in moderate to poorly differentiated prostate cancers. J. Clin. Pathol. 60, 1238-1243 (2007). (Pubitemid 350084545)
-
(2007)
Journal of Clinical Pathology
, vol.60
, Issue.11
, pp. 1238-1243
-
-
Rajput, A.B.1
Miller, M.A.2
De Luca, A.3
Boyd, N.4
Leung, S.5
Hurtado-Coll, A.6
Fazli, L.7
Jones, E.C.8
Palmer, J.B.9
Gleave, M.E.10
Cox, M.E.11
Huntsman, D.G.12
-
36
-
-
67649425225
-
ETS gene fusions in prostate cancer: From discovery to daily clinical practice
-
Tomlins, S. A. et al. ETS gene fusions in prostate cancer: from discovery to daily clinical practice. Eur. Urol. 56, 275-286 (2009).
-
(2009)
Eur. Urol.
, vol.56
, pp. 275-286
-
-
Tomlins, S.A.1
-
37
-
-
70949083943
-
Persistence of expression of the TMPRSS2:ERG fusion gene after pre-surgery androgen ablation may be associated with early prostate specific antigen relapse of prostate cancer: Preliminary results
-
Bonaccorsi, L. et al. Persistence of expression of the TMPRSS2:ERG fusion gene after pre-surgery androgen ablation may be associated with early prostate specific antigen relapse of prostate cancer: preliminary results. J. Endocrinol. Invest. 32, 590-596 (2009).
-
(2009)
J. Endocrinol. Invest.
, vol.32
, pp. 590-596
-
-
Bonaccorsi, L.1
-
38
-
-
38349047019
-
ETS transcription factors: Oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer
-
Turner, D. P. & Watson, D. K. ETS transcription factors: oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer. Expert Rev. Anticancer Ther. 8, 33-42 (2008).
-
(2008)
Expert Rev. Anticancer Ther.
, vol.8
, pp. 33-42
-
-
Turner, D.P.1
Watson, D.K.2
-
39
-
-
0023261236
-
The erg gene: A human gene related to the ets oncogene
-
Reddy, E. S., Rao, V. N. & Papas, T. S. The erg gene: a human gene related to the ets oncogene. Proc. Natl Acad. Sci. USA 84, 6131-6135 (1987). (Pubitemid 17140179)
-
(1987)
Proceedings of the National Academy of Sciences of the United States of America
, vol.84
, Issue.17
, pp. 6131-6135
-
-
Reddy, E.S.P.1
Rao, V.N.2
Papas, T.S.3
-
40
-
-
77955716677
-
ERG oncoprotein expression in prostate cancer: Clonal progression of ERG-positive tumor cells and potential for ERG-based stratification
-
Furusato, B. et al. ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification. Prostate Cancer Prostatic Dis. 13, 228-237 (2010).
-
(2010)
Prostate Cancer Prostatic Dis
, vol.13
, pp. 228-237
-
-
Furusato, B.1
-
41
-
-
77954997528
-
Antibody-based detection of ERG rearrangement-positive prostate cancer
-
Park, K. et al. Antibody-based detection of ERG rearrangement-positive prostate cancer. Neoplasia 12, 590-598 (2010).
-
(2010)
Neoplasia
, vol.12
, pp. 590-598
-
-
Park, K.1
-
42
-
-
84877040769
-
Ets family protein, erg expression in developing and adult mouse tissues by a highly specific monoclonal antibody
-
Mohamed, A. A. et al. Ets family protein, erg expression in developing and adult mouse tissues by a highly specific monoclonal antibody. J. Cancer 1, 197-208 (2010).
-
(2010)
J. Cancer
, vol.1
, pp. 197-208
-
-
Mohamed, A.A.1
-
43
-
-
51049118579
-
Delineation of TMPRSS2-ERG splice variants in prostate cancer
-
Hu, Y. et al. Delineation of TMPRSS2-ERG splice variants in prostate cancer. Clin. Cancer Res. 14, 4719-4725 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 4719-4725
-
-
Hu, Y.1
-
44
-
-
0032755112
-
Xl erg: Expression pattern and overexpression during development plead for a role in endothelial cell differentiation
-
Baltzinger, M., Mager-Heckel, A. M. & Remy, P. Xl erg: expression pattern and overexpression during development plead for a role in endothelial cell differentiation. Dev. Dyn. 216, 420-433 (1999).
-
(1999)
Dev. Dyn.
, vol.216
, pp. 420-433
-
-
Baltzinger, M.1
Mager-Heckel, A.M.2
Remy, P.3
-
45
-
-
43549123588
-
Transcription factor erg regulates angiogenesis and endothelial apoptosis through ve-cadherin
-
Birdsey, G. M. et al. Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin. Blood 111, 3498-3506 (2008).
-
(2008)
Blood
, vol.111
, pp. 3498-3506
-
-
Birdsey, G.M.1
-
46
-
-
59849105456
-
The role of the ETS factor erg in zebrafish vasculogenesis
-
Ellett, F., Kile, B. T. & Lieschke, G. J. The role of the ETS factor erg in zebrafish vasculogenesis. Mech. Dev. 126, 220-229 (2009).
-
(2009)
Mech. Dev.
, vol.126
, pp. 220-229
-
-
Ellett, F.1
Kile, B.T.2
Lieschke, G.J.3
-
47
-
-
79953059276
-
ERG transcription factor as an immunohistochemical marker for vascular endothelial tumors and prostatic carcinoma
-
Miettinen, M. et al. ERG transcription factor as an immunohistochemical marker for vascular endothelial tumors and prostatic carcinoma. Am. J. Surg. Pathol. 35, 432-441 (2011).
-
(2011)
Am. J. Surg. Pathol.
, vol.35
, pp. 432-441
-
-
Miettinen, M.1
-
48
-
-
79961031183
-
Antibody EPR3864 is specific for ERG genomic fusions in prostate cancer: Implications for pathological practice
-
van Leenders, G. J. et al. Antibody EPR3864 is specific for ERG genomic fusions in prostate cancer: implications for pathological practice. Mod. Pathol. 24, 1128-1138 (2011).
-
(2011)
Mod. Pathol.
, vol.24
, pp. 1128-1138
-
-
Van Leenders, G.J.1
-
49
-
-
79959660044
-
Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas
-
Chaux, A. et al. Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas. Am. J. Surg. Pathol. 35, 1014-1020 (2011).
-
(2011)
Am. J. Surg. Pathol.
, vol.35
, pp. 1014-1020
-
-
Chaux, A.1
-
50
-
-
80855124842
-
ERG gene rearrangement status in prostate cancer detected by immunohistochemistry
-
Falzarano, S. M. et al. ERG gene rearrangement status in prostate cancer detected by immunohistochemistry. Virchows Arch. 459, 441-447 (2011).
-
(2011)
Virchows Arch
, vol.459
, pp. 441-447
-
-
Falzarano, S.M.1
-
51
-
-
80052841071
-
ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy
-
Minner, S. et al. ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy. Clin. Cancer Res. 17, 5878-5888 (2011).
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 5878-5888
-
-
Minner, S.1
-
52
-
-
84862080503
-
ERG protein expression and genomic rearrangement status in primary and metastatic prostate cancer-a comparative study of two monoclonal antibodies
-
Braun, M. et al. ERG protein expression and genomic rearrangement status in primary and metastatic prostate cancer-a comparative study of two monoclonal antibodies. Prostate Cancer Prostatic Dis. http://dx.doi. org/10.1038/pcan.2011. 67.
-
Prostate Cancer Prostatic Dis.
-
-
Braun, M.1
-
53
-
-
79953169828
-
The diagnostic utility of novel immunohistochemical marker ERG in the workup of prostate biopsies with "atypical glands suspicious for cancer"
-
He, H. et al. The diagnostic utility of novel immunohistochemical marker ERG in the workup of prostate biopsies with "atypical glands suspicious for cancer". Am. J. Surg. Pathol. 35, 608-614 (2011).
-
(2011)
Am. J. Surg. Pathol.
, vol.35
, pp. 608-614
-
-
He, H.1
-
54
-
-
79959684555
-
The utility of erg/p63 double immunohistochemical staining in the diagnosis of limited cancer in prostate needle biopsies
-
Yaskiv, O. et al. The utility of ERG/P63 double immunohistochemical staining in the diagnosis of limited cancer in prostate needle biopsies. Am. J. Surg. Pathol. 35, 1062-1068 (2011).
-
(2011)
Am. J. Surg. Pathol.
, vol.35
, pp. 1062-1068
-
-
Yaskiv, O.1
-
55
-
-
77955176329
-
ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor
-
Scheble, V. J. et al. ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor. Mod. Pathol. 23, 1061-1067 (2010).
-
(2010)
Mod. Pathol.
, vol.23
, pp. 1061-1067
-
-
Scheble, V.J.1
-
56
-
-
33644830601
-
Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: A Cancer and Leukemia Group B study
-
Marcucci, G. et al. Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study. J. Clin. Oncol. 23, 9234-9242 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 9234-9242
-
-
Marcucci, G.1
-
57
-
-
0030871371
-
Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript
-
Kong, X. T. et al. Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript. Blood 90, 1192-1199 (1997).
-
(1997)
Blood
, vol.90
, pp. 1192-1199
-
-
Kong, X.T.1
-
58
-
-
12144290701
-
Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes
-
DOI 10.1073/pnas.0400272101
-
Baldus, C. D. et al. Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes. Proc. Natl Acad. Sci. USA 101, 3915-3920 (2004). (Pubitemid 38381077)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.11
, pp. 3915-3920
-
-
Baldus, C.D.1
Liyanarachchi, S.2
Mrozek, K.3
Auer, H.4
Tanner, S.M.5
Guimond, M.6
Ruppert, A.S.7
Mohamed, N.8
Davuluri, R.V.9
Caligiuri, M.A.10
Bloomfield, C.D.11
De La Chapelle, A.12
-
59
-
-
78651280526
-
Single focus prostate cancer: Pathological features and ERG fusion status
-
Falzarano, S. M. et al. Single focus prostate cancer: pathological features and ERG fusion status. J. Urol. 185, 489-494 (2011).
-
(2011)
J. Urol.
, vol.185
, pp. 489-494
-
-
Falzarano, S.M.1
-
60
-
-
50349093250
-
Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications
-
Mosquera, J. M. et al. Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications. Clin. Cancer Res. 14, 3380-3385 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 3380-3385
-
-
Mosquera, J.M.1
-
61
-
-
79957912763
-
ERG gene rearrangements are common in prostatic small cell carcinomas
-
Lotan, T. L. et al. ERG gene rearrangements are common in prostatic small cell carcinomas. Mod. Pathol. 24, 820-828 (2011).
-
(2011)
Mod. Pathol.
, vol.24
, pp. 820-828
-
-
Lotan, T.L.1
-
62
-
-
33749870551
-
TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions
-
DOI 10.1593/neo.06427
-
Cerveira, N. et al. TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions. Neoplasia 8, 826-832 (2006). (Pubitemid 44564838)
-
(2006)
Neoplasia
, vol.8
, Issue.10
, pp. 826-832
-
-
Cerveira, N.1
Ribeiro, F.R.2
Peixoto, A.3
Costa, V.4
Henrique, R.5
Jeronimo, C.6
Teixeira, M.R.7
-
63
-
-
34447342868
-
TMPRSS2-ERG fusion prostate cancer: An early molecular event associated with invasion
-
DOI 10.1097/01.pas.0000213424.38503.aa, PII 0000047820070600000008
-
Perner, S. et al. TMPRSS2-ERG fusion prostate cancer: an early molecular event associated with invasion. Am. J. Surg. Pathol. 31, 882-888 (2007). (Pubitemid 47165141)
-
(2007)
American Journal of Surgical Pathology
, vol.31
, Issue.6
, pp. 882-888
-
-
Perner, S.1
Mosquera, J.-M.2
Demichelis, F.3
Hofer, M.D.4
Paris, P.L.5
Simko, J.6
Collins, C.7
Bismar, T.A.8
Chinnaiyan, A.M.9
De Marzo, A.M.10
Rubin, M.A.11
-
64
-
-
41149121704
-
Complex patterns of ETS gene alteration arise during cancer development in the human prostate
-
DOI 10.1038/sj.onc.1210843, PII 1210843
-
Clark, J. et al. Complex patterns of ETS gene alteration arise during cancer development in the human prostate. Oncogene 27, 1993-2003 (2008). (Pubitemid 351442741)
-
(2008)
Oncogene
, vol.27
, Issue.14
, pp. 1993-2003
-
-
Clark, J.1
Attard, G.2
Jhavar, S.3
Flohr, P.4
Reid, A.5
De-Bono, J.6
Eeles, R.7
Scardino, P.8
Cuzick, J.9
Fisher, G.10
Parker, M.D.11
Foster, C.S.12
Berney, D.13
Kovacs, G.14
Cooper, C.S.15
-
65
-
-
85016712245
-
ERG rearrangement as a clonal expansion marker for prostate cancer
-
Braun, M., Menon, R., Nikolov, P. & Perner, S. ERG rearrangement as a clonal expansion marker for prostate cancer. The Open Prostate Cancer Journal 3, 63-68 (2010).
-
(2010)
The Open Prostate Cancer Journal
, vol.3
, pp. 63-68
-
-
Braun, M.1
Menon, R.2
Nikolov, P.3
Perner, S.4
-
66
-
-
68249083702
-
Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression
-
Han, B. et al. Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression. Mod. Pathol. 22, 1083-1093 (2009).
-
(2009)
Mod. Pathol.
, vol.22
, pp. 1083-1093
-
-
Han, B.1
-
67
-
-
33751260934
-
TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming
-
DOI 10.1158/0008-5472.CAN-06-1986
-
Iljin, K. et al. TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming. Cancer Res. 66, 10242-10246 (2006). (Pubitemid 44799738)
-
(2006)
Cancer Research
, vol.66
, Issue.21
, pp. 10242-10246
-
-
Iljin, K.1
Wolf, M.2
Edgren, H.3
Gupta, S.4
Kilpinen, S.5
Skotheim, R.I.6
Peltola, M.7
Smit, F.8
Verhaegh, G.9
Schalken, J.10
Nees, M.11
Kallioniemi, O.12
-
68
-
-
54249154706
-
Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts
-
Wang, J. et al. Pleiotropic biological activities of alternatively spliced TMPRSS2/ERG fusion gene transcripts. Cancer Res. 68, 8516-8524 (2008).
-
(2008)
Cancer Res
, vol.68
, pp. 8516-8524
-
-
Wang, J.1
-
69
-
-
78650104069
-
MYC and prostate cancer
-
Koh, C. M. et al. MYC and prostate cancer. Genes Cancer 1, 617-628 (2010).
-
(2010)
Genes Cancer
, vol.1
, pp. 617-628
-
-
Koh, C.M.1
-
70
-
-
77950192240
-
1{Alpha}, 25-dihydroxyvitamin D3 inhibits growth of vcap prostate cancer cells despite inducing the growth-promoting tmprss2:Erg gene fusion
-
Washington, M. N. & Weigel, N. L. 1{alpha}, 25-Dihydroxyvitamin D3 inhibits growth of VCaP prostate cancer cells despite inducing the growth-promoting TMPRSS2:ERG gene fusion. Endocrinology 151, 1409-1417 (2010).
-
(2010)
Endocrinology
, vol.151
, pp. 1409-1417
-
-
Washington, M.N.1
Weigel, N.L.2
-
71
-
-
33747873279
-
15-Hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer
-
DOI 10.1158/0008-5472.CAN-05-4368
-
Wolf, I. et al. 15-hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer. Cancer Res. 66, 7818-7823 (2006). (Pubitemid 44289243)
-
(2006)
Cancer Research
, vol.66
, Issue.15
, pp. 7818-7823
-
-
Wolf, I.1
O'Kelly, J.2
Rubinek, T.3
Tong, M.4
Nguyen, A.5
Lin, B.T.6
Tai, H.-H.7
Karlan, B.Y.8
Koeffler, H.P.9
-
72
-
-
33747081906
-
15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis
-
Myung, S. J. et al. 15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis. Proc. Natl Acad. Sci. USA 103, 12098-12102 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 12098-12102
-
-
Myung, S.J.1
-
73
-
-
79951846237
-
Gene fusions find an ERG-way to tumor inflammation
-
Martin, S. K. & Kyprianou, N. Gene fusions find an ERG-way to tumor inflammation. Cancer Biol. Ther. 11, 418-420 (2011).
-
(2011)
Cancer Biol. Ther.
, vol.11
, pp. 418-420
-
-
Martin, S.K.1
Kyprianou, N.2
-
74
-
-
77955069195
-
Androgen-induced top2b-mediated double-strand breaks and prostate cancer gene rearrangements
-
Haffner, M. C. et al. Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nat. Genet. 42, 668-675 (2010).
-
(2010)
Nat. Genet.
, vol.42
, pp. 668-675
-
-
Haffner, M.C.1
-
75
-
-
32044450042
-
Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: Implications for patient care
-
DOI 10.1016/S0022-5347(05)00337-X, PII S002253470500337X
-
Epstein, J. I. & Herawi, M. Prostate needle biopsies containing prostatic intraepithelial neoplasia or atypical foci suspicious for carcinoma: implications for patient care. J. Urol. 175, 820-834 (2006). (Pubitemid 43199991)
-
(2006)
Journal of Urology
, vol.175
, Issue.3
, pp. 820-834
-
-
Epstein, J.I.1
Herawi, M.2
-
76
-
-
79251536870
-
PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer
-
Bismar, T. A. et al. PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer. BJU Int. 107, 477-485 (2011).
-
(2011)
BJU Int
, vol.107
, pp. 477-485
-
-
Bismar, T.A.1
-
77
-
-
56649091295
-
Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome
-
Yoshimoto, M. et al. Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome. Mod. Pathol. 21, 1451-1460 (2008).
-
(2008)
Mod. Pathol.
, vol.21
, pp. 1451-1460
-
-
Yoshimoto, M.1
-
78
-
-
76949106361
-
Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer
-
Reid, A. H. et al. Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer. Br. J. Cancer 102, 678-684 (2010).
-
(2010)
Br. J. Cancer
, vol.102
, pp. 678-684
-
-
Reid, A.H.1
|