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Volumn 3, Issue SPEC. ISSUE 1, 2010, Pages 101-108

ERG expression levels in prostate tumors reflect functional status of the androgen receptor (AR) as a consequence of fusion of ERG with AR regulated gene promoters

Author keywords

Androgen receptor; ERG; Oncogene; Prostate cancer; TMPRSS2 ERG

Indexed keywords

ANDROGEN RECEPTOR;

EID: 78249235620     PISSN: None     EISSN: 18740790     Source Type: Journal    
DOI: 10.2174/1874079001003010101     Document Type: Article
Times cited : (12)

References (56)
  • 2
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005; 310: 644-648.
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3
  • 3
    • 39049170313 scopus 로고    scopus 로고
    • Characterization of TMPRSS2: ETV5 and SLC45A3: ETV5 gene fusions in prostate cancer
    • Helgeson BE, Tomlins SA, Shah N, et al. Characterization of TMPRSS2: ETV5 and SLC45A3: ETV5 gene fusions in prostate cancer. Cancer Res 2008; 68: 73-80.
    • (2008) Cancer Res , vol.68 , pp. 73-80
    • Helgeson, B.E.1    Tomlins, S.A.2    Shah, N.3
  • 4
    • 67650489112 scopus 로고    scopus 로고
    • N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer
    • Pflueger D, Rickman DS, Sboner A, et al. N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer. Neoplasia 2009; 11: 804-811.
    • (2009) Neoplasia , vol.11 , pp. 804-811
    • Pflueger, D.1    Rickman, D.S.2    Sboner, A.3
  • 5
    • 38349047019 scopus 로고    scopus 로고
    • ETS transcription factors: Oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer
    • Turner DP, Watson DK. ETS transcription factors: oncogenes and tumor suppressor genes as therapeutic targets for prostate cancer. Expert Rev Anticancer Ther 2008; 8: 33-42.
    • (2008) Expert Rev Anticancer Ther , vol.8 , pp. 33-42
    • Turner, D.P.1    Watson, D.K.2
  • 7
    • 70350109641 scopus 로고    scopus 로고
    • ETS gene fusions in prostate cancer
    • Clark JP, Cooper CS. ETS gene fusions in prostate cancer. Nat Rev Urol 2009; 6: 429-439.
    • (2009) Nat Rev Urol , vol.6 , pp. 429-439
    • Clark, J.P.1    Cooper, C.S.2
  • 8
    • 2342558431 scopus 로고    scopus 로고
    • Androgen receptor in prostate cancer
    • Heinlein CA, Chang C. Androgen receptor in prostate cancer. Endocr Rev 2004; 25: 276-308.
    • (2004) Endocr Rev , vol.25 , pp. 276-308
    • Heinlein, C.A.1    Chang, C.2
  • 9
    • 12344319442 scopus 로고    scopus 로고
    • Alterations of androgen receptor in prostate cancer
    • Linja MJ, Visakorpi T. Alterations of androgen receptor in prostate cancer. J Steroid Biochem Mol Biol 2004; 92: 255-264.
    • (2004) J Steroid Biochem Mol Biol , vol.92 , pp. 255-264
    • Linja, M.J.1    Visakorpi, T.2
  • 10
    • 0038642308 scopus 로고    scopus 로고
    • Prostate cancer: A dynamic illness with shifting targets
    • Shaffer DR, Scher HI. Prostate cancer: a dynamic illness with shifting targets. Lancet Oncol 2003; 4: 407-414.
    • (2003) Lancet Oncol , vol.4 , pp. 407-414
    • Shaffer, D.R.1    Scher, H.I.2
  • 11
    • 1842612441 scopus 로고    scopus 로고
    • Molecular determinants of resistance to antiandrogen therapy
    • Chen CD, Welsbie DS, Tran C, et al. Molecular determinants of resistance to antiandrogen therapy. Nat Med 2004; 10: 33-39.
    • (2004) Nat Med , vol.10 , pp. 33-39
    • Chen, C.D.1    Welsbie, D.S.2    Tran, C.3
  • 12
    • 68049137909 scopus 로고    scopus 로고
    • Targeting the PI3K/AKT pathway for the treatment of prostate cancer
    • [12] Sarker D, Reid AH, Yap TA, de Bono JS. Targeting the PI3K/AKT pathway for the treatment of prostate cancer. Clin Cancer Res 2009; 15: 4799-4805.
    • (2009) Clin Cancer Res , vol.15 , pp. 4799-4805
    • Sarker, D.1    Reid, A.H.2    Yap, T.A.3    de Bono, J.S.4
  • 13
    • 33745589772 scopus 로고    scopus 로고
    • Androgen receptor mutation (T877A) promotes prostate cancer cell growth and cell survival
    • Sun C, Shi Y, Xu LL, et al. Androgen receptor mutation (T877A) promotes prostate cancer cell growth and cell survival. Oncogene 2006; 25: 3905-3913.
    • (2006) Oncogene , vol.25 , pp. 3905-3913
    • Sun, C.1    Shi, Y.2    Xu, L.L.3
  • 14
    • 37149022032 scopus 로고    scopus 로고
    • Expression of androgen receptor is negatively regulated by p53
    • Alimirah F, Panchanathan R, Chen J, et al. Expression of androgen receptor is negatively regulated by p53. Neoplasia 2007; 9: 1152-1159.
    • (2007) Neoplasia , vol.9 , pp. 1152-1159
    • Alimirah, F.1    Panchanathan, R.2    Chen, J.3
  • 15
    • 27144458128 scopus 로고    scopus 로고
    • Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP
    • Rokhlin OW, Taghiyev AF, Guseva NV, et al. Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP. Oncogene 2005; 24: 6773-6784.
    • (2005) Oncogene , vol.24 , pp. 6773-6784
    • Rokhlin, O.W.1    Taghiyev, A.F.2    Guseva, N.V.3
  • 16
    • 33746623315 scopus 로고    scopus 로고
    • Molecular regulation of androgen action in prostate cancer
    • Dehm SM, Tindall DJ. Molecular regulation of androgen action in prostate cancer. J Cell Biochem 2006; 99: 333-344.
    • (2006) J Cell Biochem , vol.99 , pp. 333-344
    • Dehm, S.M.1    Tindall, D.J.2
  • 17
    • 34447635231 scopus 로고    scopus 로고
    • Prostate cancer: Re-focusing on androgen receptor signaling
    • Nieto M, Finn S, Loda M, Hahn WC. Prostate cancer: Re-focusing on androgen receptor signaling. Int J Biochem Cell Biol 2007; 39: 1562-1568.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1562-1568
    • Nieto, M.1    Finn, S.2    Loda, M.3    Hahn, W.C.4
  • 19
    • 49249119358 scopus 로고    scopus 로고
    • Maintenance of intratumoral androgens in metastatic prostate cancer: A mechanism for castration-resistant tumor growth
    • Montgomery RB, Mostaghel EA, Vessella R, et al. Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res 2008; 68: 4447-4454.
    • (2008) Cancer Res , vol.68 , pp. 4447-4454
    • Montgomery, R.B.1    Mostaghel, E.A.2    Vessella, R.3
  • 20
    • 20444493600 scopus 로고    scopus 로고
    • Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcrip-tome
    • Petrovics G, Liu A, Shaheduzzaman S, et al. Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcrip-tome. Oncogene 2005; 24: 3847-3852.
    • (2005) Oncogene , vol.24 , pp. 3847-3852
    • Petrovics, G.1    Liu, A.2    Shaheduzzaman, S.3
  • 21
    • 51049118579 scopus 로고    scopus 로고
    • Delineation of TMPRSS2-ERG splice variants in prostate cancer
    • Hu Y, Dobi A, Sreenath T, et al. Delineation of TMPRSS2-ERG splice variants in prostate cancer. Clin Cancer Res 2008; 14: 4719-4725.
    • (2008) Clin Cancer Res , vol.14 , pp. 4719-4725
    • Hu, Y.1    Dobi, A.2    Sreenath, T.3
  • 22
    • 0037069941 scopus 로고    scopus 로고
    • Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cells
    • Segawa T, Nau ME, Xu LL, et al. Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cells. Oncogene 2002; 21: 8749-8758.
    • (2002) Oncogene , vol.21 , pp. 8749-8758
    • Segawa, T.1    Nau, M.E.2    Xu, L.L.3
  • 23
    • 0035342537 scopus 로고    scopus 로고
    • Quantitative expression profile of androgen-regulated genes in prostate cancer cells and identification of prostate-specific genes
    • Xu LL, Su YP, Labiche R, et al. Quantitative expression profile of androgen-regulated genes in prostate cancer cells and identification of prostate-specific genes. Int J Cancer 2001; 92: 322-328.
    • (2001) Int J Cancer , vol.92 , pp. 322-328
    • Xu, L.L.1    Su, Y.P.2    Labiche, R.3
  • 24
    • 42449093747 scopus 로고    scopus 로고
    • Silencing of Lactotransferrin expression by methylation in prostate cancer progression
    • Shaheduzzaman S, Vishwanath A, Furusato B, et al. Silencing of Lactotransferrin expression by methylation in prostate cancer progression. Cancer Biol Ther 2007; 6: 1088-1095.
    • (2007) Cancer Biol Ther , vol.6 , pp. 1088-1095
    • Shaheduzzaman, S.1    Vishwanath, A.2    Furusato, B.3
  • 25
    • 0346789073 scopus 로고    scopus 로고
    • Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16
    • Owczarek CM, Portbury KJ, Hardy MP, et al. Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16. Gene 2004; 324: 65-77.
    • (2004) Gene , vol.324 , pp. 65-77
    • Owczarek, C.M.1    Portbury, K.J.2    Hardy, M.P.3
  • 26
    • 67650741782 scopus 로고    scopus 로고
    • Management of breast cancer in the genome era
    • Morrow PK, Hortobagyi GN. Management of breast cancer in the genome era. Annu Rev Med 2009; 60: 153-165.
    • (2009) Annu Rev Med , vol.60 , pp. 153-165
    • Morrow, P.K.1    Hortobagyi, G.N.2
  • 27
    • 61449096819 scopus 로고    scopus 로고
    • GnRH receptor and androgen receptor status and outcome of advanced prostate carcinomas
    • Szabo J, Bartok K, Krenacs T, Szepesvary Z, Szende B. GnRH receptor and androgen receptor status and outcome of advanced prostate carcinomas. Anticancer Res 2009; 29: 681-684.
    • (2009) Anticancer Res , vol.29 , pp. 681-684
    • Szabo, J.1    Bartok, K.2    Krenacs, T.3    Szepesvary, Z.4    Szende, B.5
  • 28
    • 58549087351 scopus 로고    scopus 로고
    • Expression of p21(waf1/cip1), p27 (kip1), p63 and androgen receptor in low and high Gleason score prostate cancer
    • Romics I, Banfi G, Szekely E, Krenacs T, Szende B. Expression of p21(waf1/cip1), p27 (kip1), p63 and androgen receptor in low and high Gleason score prostate cancer. Pathol Oncol Res 2008; 14: 307-311.
    • (2008) Pathol Oncol Res , vol.14 , pp. 307-311
    • Romics, I.1    Banfi, G.2    Szekely, E.3    Krenacs, T.4    Szende, B.5
  • 29
    • 59449092037 scopus 로고    scopus 로고
    • Androgen receptor expression in clinically localized prostate cancer: Immunohistochemistry study and literature review
    • Qiu YQ, Leuschner I, Braun PM. Androgen receptor expression in clinically localized prostate cancer: immunohistochemistry study and literature review. Asian J Androl 2008; 10: 855-863.
    • (2008) Asian J Androl , vol.10 , pp. 855-863
    • Qiu, Y.Q.1    Leuschner, I.2    Braun, P.M.3
  • 30
    • 76149107169 scopus 로고    scopus 로고
    • Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease
    • Donovan MJ, Osman I, Khan FM, et al. Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease. BJU Int 2010; 105(4): 462-467.
    • (2010) BJU Int , vol.105 , Issue.4 , pp. 462-467
    • Donovan, M.J.1    Osman, I.2    Khan, F.M.3
  • 31
    • 42049098597 scopus 로고    scopus 로고
    • Expression of androgen receptor through androgen-converting enzymes is associated with biological aggressiveness in prostate cancer
    • Wako K, Kawasaki T, Yamana K, et al. Expression of androgen receptor through androgen-converting enzymes is associated with biological aggressiveness in prostate cancer. J Clin Pathol 2008; 61: 448-454.
    • (2008) J Clin Pathol , vol.61 , pp. 448-454
    • Wako, K.1    Kawasaki, T.2    Yamana, K.3
  • 32
    • 0042591506 scopus 로고    scopus 로고
    • PMEPA1, an androgen-regulated NEDD4-binding protein, exhibits cell growth inhibitory function and decreased expression during prostate cancer progression
    • Xu LL, Shi Y, Petrovics G, et al. PMEPA1, an androgen-regulated NEDD4-binding protein, exhibits cell growth inhibitory function and decreased expression during prostate cancer progression. Cancer Res 2003; 63: 4299-4304.
    • (2003) Cancer Res , vol.63 , pp. 4299-4304
    • Xu, L.L.1    Shi, Y.2    Petrovics, G.3
  • 33
    • 0034659461 scopus 로고    scopus 로고
    • A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate
    • Xu LL, Shanmugam N, Segawa T, et al. A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate. Genomics 2000; 66: 257-263.
    • (2000) Genomics , vol.66 , pp. 257-263
    • Xu, L.L.1    Shanmugam, N.2    Segawa, T.3
  • 34
    • 26844493084 scopus 로고    scopus 로고
    • Androgen receptor binding sites identified by a GREF_GATA model
    • Masuda K, Werner T, Maheshwari S, et al. Androgen receptor binding sites identified by a GREF_GATA model. J Mol Biol 2005; 353: 763-771.
    • (2005) J Mol Biol , vol.353 , pp. 763-771
    • Masuda, K.1    Werner, T.2    Maheshwari, S.3
  • 35
    • 34547214787 scopus 로고    scopus 로고
    • A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth
    • Wang Q, Li W, Liu XS, et al. A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Mol Cell 2007; 27: 380-392.
    • (2007) Mol Cell , vol.27 , pp. 380-392
    • Wang, Q.1    Li, W.2    Liu, X.S.3
  • 36
    • 3843091606 scopus 로고    scopus 로고
    • Identification and validation of novel androgen-regulated genes in prostate cancer
    • Velasco AM, Gillis KA, Li Y, et al. Identification and validation of novel androgen-regulated genes in prostate cancer. Endocrinology 2004; 145: 3913-3924.
    • (2004) Endocrinology , vol.145 , pp. 3913-3924
    • Velasco, A.M.1    Gillis, K.A.2    Li, Y.3
  • 37
    • 67650758019 scopus 로고    scopus 로고
    • Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer
    • Wang Q, Li W, Zhang Y, et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell 2009; 138: 245-256.
    • (2009) Cell , vol.138 , pp. 245-256
    • Wang, Q.1    Li, W.2    Zhang, Y.3
  • 38
    • 37349118115 scopus 로고    scopus 로고
    • Androgen receptor (AR) coregulators: A diversity of functions converging on and regulating the AR transcriptional complex
    • Heemers HV, Tindall DJ. Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex. Endocr Rev 2007; 28: 778-808.
    • (2007) Endocr Rev , vol.28 , pp. 778-808
    • Heemers, H.V.1    Tindall, D.J.2
  • 39
    • 38949210744 scopus 로고    scopus 로고
    • Higher expression of the androgen-regulated gene PSA/HK3 mRNA in prostate cancer tissues predicts biochemical recurrence-free survival
    • Sterbis JR, Gao C, Furusato B, et al. Higher expression of the androgen-regulated gene PSA/HK3 mRNA in prostate cancer tissues predicts biochemical recurrence-free survival. Clin Cancer Res 2008; 14: 758-763.
    • (2008) Clin Cancer Res , vol.14 , pp. 758-763
    • Sterbis, J.R.1    Gao, C.2    Furusato, B.3
  • 40
    • 65349089474 scopus 로고    scopus 로고
    • Genomic strategy for targeting therapy in castration-resistant prostate cancer
    • Mendiratta P, Mostaghel E, Guinney J, et al. Genomic strategy for targeting therapy in castration-resistant prostate cancer. J Clin Oncol 2009; 27: 2022-2029.
    • (2009) J Clin Oncol , vol.27 , pp. 2022-2029
    • Mendiratta, P.1    Mostaghel, E.2    Guinney, J.3
  • 41
    • 33845884027 scopus 로고    scopus 로고
    • Integrative molecular concept modeling of prostate cancer progression
    • Tomlins SA, Mehra R, Rhodes DR, et al. Integrative molecular concept modeling of prostate cancer progression. Nat Genet 2007; 39: 41-51.
    • (2007) Nat Genet , vol.39 , pp. 41-51
    • Tomlins, S.A.1    Mehra, R.2    Rhodes, D.R.3
  • 42
    • 33845329915 scopus 로고    scopus 로고
    • TMPRSS2: ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer
    • Hermans KG, van Marion R, van Dekken H, et al. TMPRSS2: ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer. Cancer Res 2006; 66: 10658-10663.
    • (2006) Cancer Res , vol.66 , pp. 10658-10663
    • Hermans, K.G.1    van Marion, R.2    van Dekken, H.3
  • 43
    • 27644506613 scopus 로고    scopus 로고
    • Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression
    • Varambally S, Yu J, Laxman B, et al. Integrative genomic and proteomic analysis of prostate cancer reveals signatures of metastatic progression. Cancer Cell 2005; 8: 393-406.
    • (2005) Cancer Cell , vol.8 , pp. 393-406
    • Varambally, S.1    Yu, J.2    Laxman, B.3
  • 44
    • 33744905821 scopus 로고    scopus 로고
    • Evolution of the androgen receptor pathway during progression of prostate cancer
    • Hendriksen PJ, Dits NF, Kokame K, et al. Evolution of the androgen receptor pathway during progression of prostate cancer. Cancer Res 2006; 66: 5012-5020.
    • (2006) Cancer Res , vol.66 , pp. 5012-5020
    • Hendriksen, P.J.1    Dits, N.F.2    Kokame, K.3
  • 45
    • 33646421636 scopus 로고    scopus 로고
    • Defining aggressive prostate cancer using a 12-gene model
    • Bismar TA, Demichelis F, Riva A, et al. Defining aggressive prostate cancer using a 12-gene model. Neoplasia 2006; 8: 59-68.
    • (2006) Neoplasia , vol.8 , pp. 59-68
    • Bismar, T.A.1    Demichelis, F.2    Riva, A.3
  • 46
    • 0042787650 scopus 로고    scopus 로고
    • Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation
    • Magee JA, Abdulkadir SA, Milbrandt J. Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation. Cancer Cell 2003; 3: 273-283.
    • (2003) Cancer Cell , vol.3 , pp. 273-283
    • Magee, J.A.1    Abdulkadir, S.A.2    Milbrandt, J.3
  • 48
    • 51649115957 scopus 로고    scopus 로고
    • TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation
    • Sun C, Dobi A, Mohamed A, et al. TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation. Oncogene 2008; 27: 5348-5353.
    • (2008) Oncogene , vol.27 , pp. 5348-5353
    • Sun, C.1    Dobi, A.2    Mohamed, A.3
  • 49
    • 68149159298 scopus 로고    scopus 로고
    • ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells
    • Zong Y, Xin L, Goldstein AS, et al. ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells. Proc Natl Acad Sci USA 2009; 106: 12465-12470.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 12465-12470
    • Zong, Y.1    Xin, L.2    Goldstein, A.S.3
  • 50
    • 41149097040 scopus 로고    scopus 로고
    • A causal role for ERG in neoplastic transformation of prostate epithelium
    • Klezovitch O, Risk M, Coleman I, et al. A causal role for ERG in neoplastic transformation of prostate epithelium. Proc Natl Acad Sci USA 2008; 105: 2105-2110.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2105-2110
    • Klezovitch, O.1    Risk, M.2    Coleman, I.3
  • 51
    • 39049150843 scopus 로고    scopus 로고
    • Role of the TMPRSS2-ERG gene fusion in prostate cancer
    • Tomlins SA, Laxman B, Varambally S, et al. Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia 2008; 10: 177-188.
    • (2008) Neoplasia , vol.10 , pp. 177-188
    • Tomlins, S.A.1    Laxman, B.2    Varambally, S.3
  • 52
    • 34547626674 scopus 로고    scopus 로고
    • Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer
    • Winnes M, Lissbrant E, Damber JE, Stenman G. Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer. Oncol Rep 2007; 17: 1033-1036.
    • (2007) Oncol Rep , vol.17 , pp. 1033-1036
    • Winnes, M.1    Lissbrant, E.2    Damber, J.E.3    Stenman, G.4
  • 53
    • 70350231922 scopus 로고    scopus 로고
    • Overexpression of prostate-specific TMPRSS2(exon 0)-ERG fusion transcripts corresponds with favorable prognosis of prostate cancer
    • Hermans KG, Boormans JL, Gasi D, et al. Overexpression of prostate-specific TMPRSS2(exon 0)-ERG fusion transcripts corresponds with favorable prognosis of prostate cancer. Clin Cancer Res 2009; 15: 6398-6403.
    • (2009) Clin Cancer Res , vol.15 , pp. 6398-6403
    • Hermans, K.G.1    Boormans, J.L.2    Gasi, D.3
  • 54
    • 50349102353 scopus 로고    scopus 로고
    • TMPRSS2: ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis
    • Saramaki OR, Harjula AE, Martikainen PM, et al. TMPRSS2: ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis. Clin Cancer Res 2008; 14: 3395-3400.
    • (2008) Clin Cancer Res , vol.14 , pp. 3395-3400
    • Saramaki, O.R.1    Harjula, A.E.2    Martikainen, P.M.3
  • 55
    • 60549107254 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
    • Gopalan A, Leversha MA, Satagopan JM, et al. TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. Cancer Res 2009; 69: 1400-1406.
    • (2009) Cancer Res , vol.69 , pp. 1400-1406
    • Gopalan, A.1    Leversha, M.A.2    Satagopan, J.M.3
  • 56
    • 70949083943 scopus 로고    scopus 로고
    • Persistence of Expression of the tmprss2: Erg fusion gene after presurgery androgen ablation may be associated with early psa relapse of prostate cancer: Preliminary results
    • Bonaccorsi L, Nesi G, Nuti F, et al. Persistence of Expression of the tmprss2: erg fusion gene after presurgery androgen ablation may be associated with early psa relapse of prostate cancer: preliminary results. J Endocrinol Invest 2009; 32: 590-596.
    • (2009) J Endocrinol Invest , vol.32 , pp. 590-596
    • Bonaccorsi, L.1    Nesi, G.2    Nuti, F.3


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