TMPRSS2 fusions with oncogenic ETS factors in prostate cancer involve unbalanced genomic rearrangements and are associated with HDAC1 and epigenetic reprogramming

Cancer Research

Volumn 66, Issue 21, 2006, Pages 10242-10246

  Iljin, Kristiina ^a   Wolf, Maija ^a   Edgren, Henrik ^a   Gupta, Santosh ^a   Kilpinen, Sami ^a   Skotheim, Rolf I ^a,b   Peltola, Mari ^a   Smit, Frank ^c   Verhaegh, Gerald ^c   Schalken, Jack ^c   Nees, Matthias ^a   Kallioniemi, Olli ^a  

^a UNIVERSITY OF TURKU   (Finland)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; HISTONE DEACETYLASE 1; MEMBRANE PROTEIN; PROTEIN ETS; PROTEIN TMPRSS 2; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; WNT PROTEIN;

ARTICLE; CELL DEATH; CLINICAL ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; EPIGENETICS; GENE EXPRESSION; GENE FUSION; GENE TARGETING; GENE TRANSLOCATION; GENOMICS; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CELL LINE, TUMOR; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; GENE FUSION; GENE REARRANGEMENT; HISTONE DEACETYLASES; HUMANS; MALE; NUCLEIC ACID HYBRIDIZATION; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-ETS; SERINE ENDOPEPTIDASES; TRANS-ACTIVATORS;

EID: 33751260934     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-1986     Document Type: Article

References (20)

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