메뉴 건너뛰기




Volumn 35, Issue 7, 2011, Pages 1014-1020

Immunohistochemistry for ERG expression as a surrogate for TMPRSS2-ERG fusion detection in prostatic adenocarcinomas

Author keywords

Edel; ERG expression; Esplit; fluorescence in situ hybridization; prostate adenocarcinoma; TMPRSS2 ERG fusion

Indexed keywords

BIOLOGICAL MARKER; DNA; ERG PROTEIN, HUMAN; ONCOPROTEIN; TMPRSS2 ERG FUSION PROTEIN, HUMAN; TMPRSS2-ERG FUSION PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TUMOR MARKER;

EID: 79959660044     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e31821e8761     Document Type: Article
Times cited : (140)

References (46)
  • 1
    • 70350686099 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion status in minute (minimal) prostatic adenocarcinoma
    • Albadine R, Latour M, Toubaji A, et al. TMPRSS2-ERG gene fusion status in minute (minimal) prostatic adenocarcinoma. Mod Pathol. 2009;22:1415-1422.
    • (2009) Mod Pathol , vol.22 , pp. 1415-1422
    • Albadine, R.1    Latour, M.2    Toubaji, A.3
  • 2
    • 38049123346 scopus 로고    scopus 로고
    • Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer
    • Attard G, Clark J, Ambroisine L, et al. Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. Oncogene. 2008;27:253-263.
    • (2008) Oncogene , vol.27 , pp. 253-263
    • Attard, G.1    Clark, J.2    Ambroisine, L.3
  • 3
    • 35648948853 scopus 로고    scopus 로고
    • TMPRSS2-ERG Fusion Heterogeneity in Multifocal Prostate Cancer: Clinical and Biologic Implications
    • DOI 10.1016/j.urology.2007.08.032, PII S0090429507020146
    • Barry M, Perner S, Demichelis F, et al. TMPRSS2-ERG fusion heterogeneity in multifocal prostate cancer: clinical and biologic implications. Urology. 2007;70:630-633. (Pubitemid 350030260)
    • (2007) Urology , vol.70 , Issue.4 , pp. 630-633
    • Barry, M.1    Perner, S.2    Demichelis, F.3    Rubin, M.A.4
  • 4
    • 66749188650 scopus 로고    scopus 로고
    • Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
    • Carver BS, Tran J, Gopalan A, et al. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat Genet. 2009;41:619-624.
    • (2009) Nat Genet , vol.41 , pp. 619-624
    • Carver, B.S.1    Tran, J.2    Gopalan, A.3
  • 5
    • 70350109641 scopus 로고    scopus 로고
    • ETS gene fusions in prostate cancer
    • Clark JP, Cooper CS. ETS gene fusions in prostate cancer. Nat Rev Urol. 2009;6:429-439.
    • (2009) Nat Rev Urol , vol.6 , pp. 429-439
    • Clark, J.P.1    Cooper, C.S.2
  • 7
    • 0031657584 scopus 로고    scopus 로고
    • Of bombers, radiologists, and cardiologists: Time to ROC
    • Collinson P. Of bombers, radiologists, and cardiologists: time to ROC. Heart. 1998;80:215-217.
    • (1998) Heart , vol.80 , pp. 215-217
    • Collinson, P.1
  • 9
    • 77950518687 scopus 로고    scopus 로고
    • Prevalence of TMPRSS2- ERG and SLC45A3-ERG gene fusions in a large prostatectomy cohort
    • Esgueva R, Perner S, J LaFargue C, et al. Prevalence of TMPRSS2- ERG and SLC45A3-ERG gene fusions in a large prostatectomy cohort. Mod Pathol. 2010;23:539-546.
    • (2010) Mod Pathol , vol.23 , pp. 539-546
    • Esgueva, R.1    Perner, S.2    Lafargue, C.J.3
  • 10
    • 77957604323 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion is associated with low Gleason scores and not with high-grade morphological features
    • Fine SW, Gopalan A, Leversha MA, et al. TMPRSS2-ERG gene fusion is associated with low Gleason scores and not with high-grade morphological features. Mod Pathol. 2010;23:1325-1333.
    • (2010) Mod Pathol , vol.23 , pp. 1325-1333
    • Fine, S.W.1    Gopalan, A.2    Leversha, M.A.3
  • 11
    • 50549095607 scopus 로고    scopus 로고
    • Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: Results from a population-based study of prostate cancer
    • FitzGerald LM, Agalliu I, Johnson K, et al. Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer. BMC Cancer. 2008;8:230.
    • (2008) BMC Cancer , vol.8 , pp. 230
    • Fitzgerald, L.M.1    Agalliu, I.2    Johnson, K.3
  • 13
    • 77955716677 scopus 로고    scopus 로고
    • ERG oncoprotein expression in prostate cancer: Clonal progression of ERG-positive tumor cells and potential for ERG-based stratification
    • Furusato B, Tan SH, Young D, et al. ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification. Prostate Cancer Prostatic Dis. 2010;13:228-237.
    • (2010) Prostate Cancer Prostatic Dis , vol.13 , pp. 228-237
    • Furusato, B.1    Tan, S.H.2    Young, D.3
  • 14
    • 60549107254 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy
    • Gopalan A, Leversha MA, Satagopan JM, et al. TMPRSS2-ERG gene fusion is not associated with outcome in patients treated by prostatectomy. Cancer Res. 2009;69:1400-1406.
    • (2009) Cancer Res , vol.69 , pp. 1400-1406
    • Gopalan, A.1    Leversha, M.A.2    Satagopan, J.M.3
  • 15
    • 54749111457 scopus 로고    scopus 로고
    • A fluorescence in situ hybridization screen for E26 transformation- specific aberrations: Identification of DDX5-ETV4 fusion protein in prostate cancer
    • Han B, Mehra R, Dhanasekaran SM, et al. A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer. Cancer Res. 2008;68:7629-7637.
    • (2008) Cancer Res , vol.68 , pp. 7629-7637
    • Han, B.1    Mehra, R.2    Dhanasekaran, S.M.3
  • 16
    • 68249083702 scopus 로고    scopus 로고
    • Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression
    • Han B, Mehra R, Lonigro RJ, et al. Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression. Mod Pathol. 2009;22:1083-1093.
    • (2009) Mod Pathol , vol.22 , pp. 1083-1093
    • Han, B.1    Mehra, R.2    Lonigro, R.J.3
  • 17
    • 33845329915 scopus 로고    scopus 로고
    • TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer
    • DOI 10.1158/0008-5472.CAN-06-1871
    • Hermans KG, van Marion R, van Dekken H, et al. TMPRSS2: ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer. Cancer Res. 2006; 66:10658-10663. (Pubitemid 44876959)
    • (2006) Cancer Research , vol.66 , Issue.22 , pp. 10658-10663
    • Hermans, K.G.1    Van Marion, R.2    Van Dekken, H.3    Jenster, G.4    Van Weerden, W.M.5    Trapman, J.6
  • 22
    • 61349195117 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusions are infrequent in prostatic ductal adenocarcinomas
    • Lotan TL, Toubaji A, Albadine R, et al. TMPRSS2-ERG gene fusions are infrequent in prostatic ductal adenocarcinomas. Mod Pathol. 2009;22:359-365.
    • (2009) Mod Pathol , vol.22 , pp. 359-365
    • Lotan, T.L.1    Toubaji, A.2    Albadine, R.3
  • 23
    • 67649805085 scopus 로고    scopus 로고
    • Molecular biology underlying the clinical heterogeneity of prostate cancer: An update
    • Mackinnon AC, Yan BC, Joseph LJ, et al. Molecular biology underlying the clinical heterogeneity of prostate cancer: an update. Arch Pathol Lab Med. 2009;133:1033-1040.
    • (2009) Arch Pathol Lab Med , vol.133 , pp. 1033-1040
    • MacKinnon, A.C.1    Yan, B.C.2    Joseph, L.J.3
  • 25
    • 45549090259 scopus 로고    scopus 로고
    • Characterization of TMPRSS2- ETS gene aberrations in androgen-independent metastatic prostate cancer
    • Mehra R, Tomlins SA, Yu J, et al. Characterization of TMPRSS2- ETS gene aberrations in androgen-independent metastatic prostate cancer. Cancer Res. 2008;68:3584-3590.
    • (2008) Cancer Res , vol.68 , pp. 3584-3590
    • Mehra, R.1    Tomlins, S.A.2    Yu, J.3
  • 26
    • 50349093250 scopus 로고    scopus 로고
    • Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications
    • Mosquera JM, Perner S, Genega EM, et al. Characterization of TMPRSS2-ERG fusion high-grade prostatic intraepithelial neoplasia and potential clinical implications. Clin Cancer Res. 2008;14:3380-3385.
    • (2008) Clin Cancer Res , vol.14 , pp. 3380-3385
    • Mosquera, J.M.1    Perner, S.2    Genega, E.M.3
  • 27
    • 68049101459 scopus 로고    scopus 로고
    • Prevalence of TMPRSS2- ERG fusion prostate cancer among men undergoing prostate biopsy in the United States
    • Mosquera JM,Mehra R, Regan MM, et al. Prevalence of TMPRSS2- ERG fusion prostate cancer among men undergoing prostate biopsy in the United States. Clin Cancer Res. 2009;15:4706-4711.
    • (2009) Clin Cancer Res , vol.15 , pp. 4706-4711
    • Mosquera Jmmehra, R.1    Regan, M.M.2
  • 29
    • 51449107401 scopus 로고    scopus 로고
    • Fusion in the ETS gene family and prostate cancer
    • Narod SA, Seth A, Nam R. Fusion in the ETS gene family and prostate cancer. Br J Cancer. 2008;99:847-851.
    • (2008) Br J Cancer , vol.99 , pp. 847-851
    • Narod, S.A.1    Seth, A.2    Nam, R.3
  • 30
    • 77954997528 scopus 로고    scopus 로고
    • Antibody-based detection of ERG rearrangement-positive prostate cancer
    • Park K, Tomlins SA, Mudaliar KM, et al. Antibody-based detection of ERG rearrangement-positive prostate cancer. Neoplasia. 2010;12: 590-598.
    • (2010) Neoplasia , vol.12 , pp. 590-598
    • Park, K.1    Tomlins, S.A.2    Mudaliar, K.M.3
  • 34
    • 67650489112 scopus 로고    scopus 로고
    • N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer
    • Pflueger D, Rickman DS, Sboner A, et al. N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer. Neoplasia. 2009;11:804-811.
    • (2009) Neoplasia , vol.11 , pp. 804-811
    • Pflueger, D.1    Rickman, D.S.2    Sboner, A.3
  • 35
    • 78651476339 scopus 로고    scopus 로고
    • Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing
    • Pflueger D, Terry S, Sboner A, et al. Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing. Genome Res. 2011;21:56-67.
    • (2011) Genome Res , vol.21 , pp. 56-67
    • Pflueger, D.1    Terry, S.2    Sboner, A.3
  • 36
    • 50349102353 scopus 로고    scopus 로고
    • TMPRSS2: ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis
    • Saramaki OR, Harjula AE, Martikainen PM, et al. TMPRSS2: ERG fusion identifies a subgroup of prostate cancers with a favorable prognosis. Clin Cancer Res. 2008;14:3395-3400.
    • (2008) Clin Cancer Res , vol.14 , pp. 3395-3400
    • Saramaki, O.R.1    Harjula, A.E.2    Martikainen, P.M.3
  • 37
    • 77955176329 scopus 로고    scopus 로고
    • ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor
    • Scheble VJ, Braun M, Beroukhim R, et al. ERG rearrangement is specific to prostate cancer and does not occur in any other common tumor. Mod Pathol. 2010;23:1061-1067.
    • (2010) Mod Pathol , vol.23 , pp. 1061-1067
    • Scheble, V.J.1    Braun, M.2    Beroukhim, R.3
  • 38
    • 63249118690 scopus 로고    scopus 로고
    • Screening and prostate-cancer mortality in a randomized European study
    • Schroder FH, Hugosson J, Roobol MJ, et al. Screening and prostate-cancer mortality in a randomized European study. N Engl J Med. 2009;360:1320-1328.
    • (2009) N Engl J Med , vol.360 , pp. 1320-1328
    • Schroder, F.H.1    Hugosson, J.2    Roobol, M.J.3
  • 40
    • 67649425225 scopus 로고    scopus 로고
    • ETS gene fusions in prostate cancer: From discovery to daily clinical practice
    • Tomlins SA, Bjartell A, Chinnaiyan AM, et al. ETS gene fusions in prostate cancer: from discovery to daily clinical practice. Eur Urol. 2009;56:275-286.
    • (2009) Eur Urol , vol.56 , pp. 275-286
    • Tomlins, S.A.1    Bjartell, A.2    Chinnaiyan, A.M.3
  • 41
    • 80455174007 scopus 로고    scopus 로고
    • Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas
    • In press
    • Toubaji A, Albadine R, Meeker A, et al. Increased gene copy number of ERG on chromosome 21 but not TMPRSS2-ERG fusion predicts outcome in prostatic adenocarcinomas. Mod Pathol. 2011 (In press).
    • (2011) Mod Pathol.
    • Toubaji, A.1    Albadine, R.2    Meeker, A.3
  • 42
    • 34547936357 scopus 로고    scopus 로고
    • Gene fusions between TMPRSS2 and ETS family genes in prostate cancer: Frequency and transcript variant analysis by RT-PCR and FISH on paraffin-embedded tissues
    • DOI 10.1038/modpathol.3800903, PII 3800903
    • Tu JJ, Rohan S, Kao J, et al. Gene fusions between TMPRSS2 and ETS family genes in prostate cancer: frequency and transcript variant analysis by RT-PCR and FISH on paraffin-embedded tissues. Mod Pathol. 2007;20:921-928. (Pubitemid 47267823)
    • (2007) Modern Pathology , vol.20 , Issue.9 , pp. 921-928
    • Tu, J.J.1    Rohan, S.2    Kao, J.3    Kitabayashi, N.4    Mathew, S.5    Chen, Y.-T.6
  • 43
    • 33749034498 scopus 로고    scopus 로고
    • Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer
    • DOI 10.1158/0008-5472.CAN-06-1966
    • Wang J, Cai Y, Ren C, et al. Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer. Cancer Res. 2006;66:8347-8351. (Pubitemid 44449142)
    • (2006) Cancer Research , vol.66 , Issue.17 , pp. 8347-8351
    • Wang, J.1    Cai, Y.2    Ren, C.3    Ittmann, M.4
  • 44
    • 34547626674 scopus 로고    scopus 로고
    • Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer
    • Winnes M, Lissbrant E, Damber JE, et al. Molecular genetic analyses of the TMPRSS2-ERG and TMPRSS2-ETV1 gene fusions in 50 cases of prostate cancer. Oncol Rep. 2007;17: 1033-1036.
    • (2007) Oncol Rep , vol.17 , pp. 1033-1036
    • Winnes, M.1    Lissbrant, E.2    Damber, J.E.3
  • 45
    • 33745808783 scopus 로고    scopus 로고
    • Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement
    • DOI 10.1593/neo.06283
    • Yoshimoto M, Joshua AM, Chilton-Macneill S, et al. Three-color FISH analysis of TMPRSS2/ERG fusions in prostate cancer indicates that genomic microdeletion of chromosome 21 is associated with rearrangement. Neoplasia. 2006;8:465-469. (Pubitemid 44035330)
    • (2006) Neoplasia , vol.8 , Issue.6 , pp. 465-469
    • Yoshimoto, M.1    Joshua, A.M.2    Chilton-MacNeill, S.3    Bayani, J.4    Selvarajah, S.5    Evans, A.J.6    Zielenska, M.7    Squire, J.A.8
  • 46
    • 56649091295 scopus 로고    scopus 로고
    • Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome
    • Yoshimoto M, Joshua AM, Cunha IW, et al. Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome. Mod Pathol. 2008;21: 1451-1460.
    • (2008) Mod Pathol , vol.21 , pp. 1451-1460
    • Yoshimoto, M.1    Joshua, A.M.2    Cunha, I.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.