-
1
-
-
27744561701
-
The glucocorticoid-induced tumor necrosis factor receptor-related gene modulates the response to Candida albicans infection
-
DOI 10.1128/IAI.73.11.7502-7508.2005
-
Agostini M, Cenci E, Pericolini E, Nocentini G, Bistoni G, Vecchiarelli A, et al,. (2005). The glucocorticoid-induced tumor necrosis factor receptor-related gene modulates the response to Candida albicans infection. Infect Immun 73: 7502-7508. (Pubitemid 41587655)
-
(2005)
Infection and Immunity
, vol.73
, Issue.11
, pp. 7502-7508
-
-
Agostini, M.1
Cenci, E.2
Pericolini, E.3
Nocentini, G.4
Bistoni, G.5
Vecchiarelli, A.6
Riccardi, C.7
-
2
-
-
78650091928
-
Role of the glucocorticoid-induced TNFR-related protein (GITR)-GITR ligand pathway in innate and adaptive immunity
-
Azuma M, (2010). Role of the glucocorticoid-induced TNFR-related protein (GITR)-GITR ligand pathway in innate and adaptive immunity. Crit Rev Immunol 30: 547-557.
-
(2010)
Crit Rev Immunol
, vol.30
, pp. 547-557
-
-
Azuma, M.1
-
3
-
-
34247863712
-
Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis
-
DOI 10.1111/j.1365-2249.2007.03363.x
-
Bae E, Kim WJ, Kang YM, Suk K, Koh EM, Cha HS, et al,. (2007). Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis. Clin Exp Immunol 148: 410-418. (Pubitemid 46701026)
-
(2007)
Clinical and Experimental Immunology
, vol.148
, Issue.3
, pp. 410-418
-
-
Bae, E.1
Kim, W.-J.2
Kang, Y.-M.3
Suk, K.4
Koh, E.-M.5
Cha, H.-S.6
Ahn, K.-S.7
Huh, T.-L.8
Lee, W.-H.9
-
4
-
-
34548255796
-
Reverse signaling initiated from GITRL induces NF-κB activation through ERK in the inflammatory activation of macrophages
-
DOI 10.1016/j.molimm.2007.05.013, PII S0161589007002295
-
Bae EM, Kim WJ, Suk K, Kang YM, Park JE, Kim WY, et al,. (2008). Reverse signaling initiated from GITRL induces NF-kappaB activation through ERK in the inflammatory activation of macrophages. Mol Immunol 45: 523-533. (Pubitemid 47332628)
-
(2008)
Molecular Immunology
, vol.45
, Issue.2
, pp. 523-533
-
-
Bae, E.M.1
Kim, W.-J.2
Suk, K.3
Kang, Y.-M.4
Park, J.-E.5
Kim, W.Y.6
Choi, E.M.7
Choi, B.K.8
Kwon, B.S.9
Lee, W.-H.10
-
5
-
-
59149095895
-
Glucocorticoid-induced tumor necrosis factor receptor-related protein ligand subverts immunosurveillance of acute myeloid leukemia in humans
-
Baessler T, Krusch M, Schmiedel BJ, Kloss M, Baltz KM, Wacker A, et al,. (2009). Glucocorticoid-induced tumor necrosis factor receptor-related protein ligand subverts immunosurveillance of acute myeloid leukemia in humans. Cancer Res 69: 1037-1045.
-
(2009)
Cancer Res
, vol.69
, pp. 1037-1045
-
-
Baessler, T.1
Krusch, M.2
Schmiedel, B.J.3
Kloss, M.4
Baltz, K.M.5
Wacker, A.6
-
6
-
-
34547791385
-
Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions
-
DOI 10.1096/fj.06-7724com
-
Baltz KM, Krusch M, Bringmann A, Brossart P, Mayer F, Kloss M, et al,. (2007). Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions. FASEB J 21: 2442-2454. (Pubitemid 47230674)
-
(2007)
FASEB Journal
, vol.21
, Issue.10
, pp. 2442-2454
-
-
Baltz, K.M.1
Krusch, M.2
Bringmann, A.3
Brossart, P.4
Mayer, F.5
Kloss, M.6
Baessler, T.7
Kumbier, I.8
Peterfi, A.9
Kupka, S.10
Kroeber, S.11
Menzel, D.12
Radsak, M.P.13
Rammensee, H.-G.14
Salih, H.R.15
-
7
-
-
55749098643
-
Neutralization of tumor-derived soluble glucocorticoid-induced TNFR-related protein ligand increases NK cell anti-tumor reactivity
-
Baltz KM, Krusch M, Baessler T, Schmiedel BJ, Bringmann A, Brossart P, et al,. (2008). Neutralization of tumor-derived soluble glucocorticoid-induced TNFR-related protein ligand increases NK cell anti-tumor reactivity. Blood 112: 3735-3743.
-
(2008)
Blood
, vol.112
, pp. 3735-3743
-
-
Baltz, K.M.1
Krusch, M.2
Baessler, T.3
Schmiedel, B.J.4
Bringmann, A.5
Brossart, P.6
-
8
-
-
79960718028
-
CD4(+) CD25(low) GITR(+) cells: A novel human CD4(+) T cell population with regulatory activity
-
Bianchini R, Bistoni O, Alunno A, Petrillo MG, Ronchetti S, Sportoletti P, et al,. (2011). CD4(+) CD25(low) GITR(+) cells: a novel human CD4(+) T cell population with regulatory activity. Eur J Immunol 41: 2269-2278.
-
(2011)
Eur J Immunol
, vol.41
, pp. 2269-2278
-
-
Bianchini, R.1
Bistoni, O.2
Alunno, A.3
Petrillo, M.G.4
Ronchetti, S.5
Sportoletti, P.6
-
9
-
-
70449637946
-
Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy
-
Boczkowski D, Lee J, Pruitt S, Nair S, (2009). Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy. Cancer Gene Ther 16: 900-911.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 900-911
-
-
Boczkowski, D.1
Lee, J.2
Pruitt, S.3
Nair, S.4
-
10
-
-
33744944082
-
Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human
-
DOI 10.1074/jbc.M601553200
-
Bossen C, Ingold K, Tardivel A, Bodmer JL, Gaide O, Hertig S, et al,. (2006). Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J Biol Chem 281: 13964-13971. (Pubitemid 43848322)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.20
, pp. 13964-13971
-
-
Bossen, C.1
Ingold, K.2
Tardivel, A.3
Bodmer, J.-L.4
Gaide, O.5
Hertig, S.6
Ambrose, C.7
Tschopp, J.8
Schneider, P.9
-
11
-
-
77949732330
-
Plasmodium vivax: Induction of CD4+CD25+FoxP3+ regulatory T cells during infection are directly associated with level of circulating parasites
-
Bueno LL, Morais CG, Araujo FF, Gomes JA, Correa-Oliveira R, Soares IS, et al,. (2010). Plasmodium vivax: induction of CD4+CD25+FoxP3+ regulatory T cells during infection are directly associated with level of circulating parasites. PLoS ONE 5: e9623.
-
(2010)
PLoS ONE
, vol.5
-
-
Bueno, L.L.1
Morais, C.G.2
Araujo, F.F.3
Gomes, J.A.4
Correa-Oliveira, R.5
Soares, I.S.6
-
12
-
-
78149284338
-
Tumor-specific crosslinking of GITR as costimulation for immunotherapy
-
Burckhart T, Thiel M, Nishikawa H, Wuest T, Muller D, Zippelius A, et al,. (2010). Tumor-specific crosslinking of GITR as costimulation for immunotherapy. J Immunother 33: 925-934.
-
(2010)
J Immunother
, vol.33
, pp. 925-934
-
-
Burckhart, T.1
Thiel, M.2
Nishikawa, H.3
Wuest, T.4
Muller, D.5
Zippelius, A.6
-
13
-
-
33947667952
-
+ regulatory T cells without enhancing effector T-cell function
-
DOI 10.1111/j.1600-6143.2006.01716.x
-
Bushell A, Wood K, (2007). GITR ligation blocks allograft protection by induced CD25+CD4+ regulatory T cells without enhancing effector T-cell function. Am J Transplant 7: 759-768. (Pubitemid 46486618)
-
(2007)
American Journal of Transplantation
, vol.7
, Issue.4
, pp. 759-768
-
-
Bushell, A.1
Wood, K.2
-
14
-
-
79958126215
-
Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: Ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation
-
Byrne AM, Goleva E, Leung DY, (2009). Identification of glucocorticoid-induced TNF receptor-related protein ligand on keratinocytes: ligation by GITR induces keratinocyte chemokine production and augments T-cell proliferation. J Invest Dermatol 129: 2784-2794.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 2784-2794
-
-
Byrne, A.M.1
Goleva, E.2
Leung, D.Y.3
-
15
-
-
78650280216
-
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells
-
Cabezon R, Sintes J, Llinas L, Benitez-Ribas D, (2011). Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol Lett 134: 167-173.
-
(2011)
Immunol Lett
, vol.134
, pp. 167-173
-
-
Cabezon, R.1
Sintes, J.2
Llinas, L.3
Benitez-Ribas, D.4
-
16
-
-
13444303994
-
Bypassing tumor-associated immune suppression with recombinant adenovirus constructs expressing membrane bound or secreted GITR-L
-
DOI 10.1038/sj.cgt.7700781
-
Calmels B, Paul S, Futin N, Ledoux C, Stoeckel F, Acres B, (2005). Bypassing tumor-associated immune suppression with recombinant adenovirus constructs expressing membrane bound or secreted GITR-L. Cancer Gene Ther 12: 198-205. (Pubitemid 40205100)
-
(2005)
Cancer Gene Therapy
, vol.12
, Issue.2
, pp. 198-205
-
-
Calmels, B.1
Paul, S.2
Futin, N.3
Ledoux, C.4
Stoeckel, F.5
Acres, B.6
-
17
-
-
33644777428
-
Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes
-
DOI 10.1016/j.jaci.2005.11.037, PII S0091674905025959
-
Cardona ID, Goleva E, Ou LS, Leung DY, (2006). Staphylococcal enterotoxin B inhibits regulatory T cells by inducing glucocorticoid-induced TNF receptor-related protein ligand on monocytes. J Allergy Clin Immunol 117: 688-695. (Pubitemid 43340237)
-
(2006)
Journal of Allergy and Clinical Immunology
, vol.117
, Issue.3
, pp. 688-695
-
-
Cardona, I.D.1
Goleva, E.2
Ou, L.-S.3
Leung, D.Y.M.4
-
18
-
-
37649005414
-
Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function
-
Chattopadhyay K, Ramagopal UA, Mukhopadhaya A, Malashkevich VN, Dilorenzo TP, Brenowitz M, et al,. (2007). Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: implications for function. Proc Natl Acad Sci USA 104: 19452-19457.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19452-19457
-
-
Chattopadhyay, K.1
Ramagopal, U.A.2
Mukhopadhaya, A.3
Malashkevich, V.N.4
Dilorenzo, T.P.5
Brenowitz, M.6
-
19
-
-
38649090326
-
Evolution of GITRL immune function: Murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily
-
DOI 10.1073/pnas.0710529105
-
Chattopadhyay K, Ramagopal UA, Brenowitz M, Nathenson SG, Almo SC, (2008). Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily. Proc Natl Acad Sci U S A 105: 635-640. (Pubitemid 351171760)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.2
, pp. 635-640
-
-
Chattopadhyay, K.1
Ramagopal, U.A.2
Brenowitz, M.3
Nathenson, S.G.4
Almo, S.C.5
-
20
-
-
65349102966
-
Sequence, structure, function, immunity: Structural genomics of costimulation
-
Chattopadhyay K, Lazar-Molnar E, Yan Q, Rubinstein R, Zhan C, Vigdorovich V, et al,. (2009). Sequence, structure, function, immunity: structural genomics of costimulation. Immunol Rev 229: 356-386.
-
(2009)
Immunol Rev
, vol.229
, pp. 356-386
-
-
Chattopadhyay, K.1
Lazar-Molnar, E.2
Yan, Q.3
Rubinstein, R.4
Zhan, C.5
Vigdorovich, V.6
-
21
-
-
51149101887
-
Co-inhibitory roles for glucocorticoid-induced TNF receptor in CD1d-dependent natural killer T cells
-
Chen S, Ndhlovu LC, Takahashi T, Takeda K, Ikarashi Y, Kikuchi T, et al,. (2008). Co-inhibitory roles for glucocorticoid-induced TNF receptor in CD1d-dependent natural killer T cells. Eur J Immunol 38: 2229-2240.
-
(2008)
Eur J Immunol
, vol.38
, pp. 2229-2240
-
-
Chen, S.1
Ndhlovu, L.C.2
Takahashi, T.3
Takeda, K.4
Ikarashi, Y.5
Kikuchi, T.6
-
22
-
-
67349285372
-
Localized expression of GITR-L in the tumor microenvironment promotes CD8+ T cell dependent anti-tumor immunity
-
Cho JS, Hsu JV, Morrison SL, (2009). Localized expression of GITR-L in the tumor microenvironment promotes CD8+ T cell dependent anti-tumor immunity. Cancer Immunol Immunother 58: 1057-1069.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 1057-1069
-
-
Cho, J.S.1
Hsu, J.V.2
Morrison, S.L.3
-
23
-
-
77955515915
-
Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy
-
Coe D, Begom S, Addey C, White M, Dyson J, Chai JG, (2010). Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy. Cancer Immunol Immunother 59: 1367-1377.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 1367-1377
-
-
Coe, D.1
Begom, S.2
Addey, C.3
White, M.4
Dyson, J.5
Chai, J.G.6
-
24
-
-
77955279163
-
Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation
-
Cohen AD, Schaer DA, Liu C, Li Y, Hirschhorn-Cymmerman D, Kim SC, et al,. (2010). Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation. PLoS ONE 5: e10436.
-
(2010)
PLoS ONE
, vol.5
-
-
Cohen, A.D.1
Schaer, D.A.2
Liu, C.3
Li, Y.4
Hirschhorn-Cymmerman, D.5
Kim, S.C.6
-
25
-
-
33646869754
-
Functional regulatory T cells are collected in stem cell autografts by mobilization with high-dose cyclophosphamide and granulocyte colony-stimulating factor
-
Condomines M, Quittet P, Lu ZY, Nadal L, Latry P, Lopez E, et al,. (2006). Functional regulatory T cells are collected in stem cell autografts by mobilization with high-dose cyclophosphamide and granulocyte colony-stimulating factor. J Immunol 176: 6631-6639. (Pubitemid 43787846)
-
(2006)
Journal of Immunology
, vol.176
, Issue.11
, pp. 6631-6639
-
-
Condomines, M.1
Quittet, P.2
Lu, Z.-Y.3
Nadal, L.4
Latry, P.5
Lopez, E.6
Baudard, M.7
Requirand, G.8
Duperray, C.9
Schved, J.-F.10
Rossi, J.-F.11
Tarte, K.12
Klein, B.13
-
26
-
-
10744226674
-
+ regulatory thymocytes
-
DOI 10.1182/blood-2003-04-1320
-
Cosmi L, Liotta F, Lazzeri E, Francalanci M, Angeli R, Mazzinghi B, et al,. (2003). Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes. Blood 102: 4107-4114. (Pubitemid 37486995)
-
(2003)
Blood
, vol.102
, Issue.12
, pp. 4107-4114
-
-
Cosmi, L.1
Liotta, F.2
Lazzeri, E.3
Francalanci, M.4
Angeli, R.5
Mazzinghi, B.6
Santarlasci, V.7
Manetti, R.8
Vanini, V.9
Romagnani, P.10
Maggi, E.11
Romagnani, S.12
Annunziato, F.13
-
27
-
-
77957264257
-
An isoleucine-zipper motif enhances costimulation of human soluble trimeric GITR ligand
-
Cui D, Wang S, Chen Y, Tong J, Ma J, Tang L, et al,. (2010). An isoleucine-zipper motif enhances costimulation of human soluble trimeric GITR ligand. Cell Mol Immunol 7: 316-322.
-
(2010)
Cell Mol Immunol
, vol.7
, pp. 316-322
-
-
Cui, D.1
Wang, S.2
Chen, Y.3
Tong, J.4
Ma, J.5
Tang, L.6
-
28
-
-
7644238339
-
Glucocorficoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock
-
DOI 10.1189/jlb.0204110
-
Cuzzocrea S, Nocentini G, Di Paola R, Mazzon E, Ronchetti S, Genovese T, et al,. (2004). Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock. J Leukoc Biol 76: 933-940. (Pubitemid 39458705)
-
(2004)
Journal of Leukocyte Biology
, vol.76
, Issue.5
, pp. 933-940
-
-
Cuzzocrea, S.1
Nocentini, G.2
Di Paola, R.3
Mazzon, E.4
Ronchetti, S.5
Genovese, T.6
Muia, C.7
Caputi, A.P.8
Riccardi, C.9
-
29
-
-
23444462753
-
Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis
-
DOI 10.1096/fj.04-3556com
-
Cuzzocrea S, Ayroldi E, Di Paola R, Agostini M, Mazzon E, Bruscoli S, et al,. (2005). Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis. FASEB J 19: 1253-1265. (Pubitemid 41113722)
-
(2005)
FASEB Journal
, vol.19
, Issue.10
, pp. 1253-1265
-
-
Cuzzocrea, S.1
Ayroldi, E.2
Di Paola, R.3
Agostini, M.4
Mazzon, E.5
Bruscoli, S.6
Genovese, T.7
Ronchetti, S.8
Caputi, A.P.9
Riccardi, C.10
-
30
-
-
33745293611
-
Proinflammatory role of glucocorticoid-induced TNF receptor-related gene in acute lung inflammation
-
Cuzzocrea S, Nocentini G, Di Paola R, Agostini M, Mazzon E, Ronchetti S, et al,. (2006). Proinflammatory role of glucocorticoid-induced TNF receptor-related gene in acute lung inflammation. J Immunol 177: 631-641. (Pubitemid 43939177)
-
(2006)
Journal of Immunology
, vol.177
, Issue.1
, pp. 631-641
-
-
Cuzzocrea, S.1
Nocentini, G.2
Di Paola, R.3
Agostini, M.4
Mazzon, E.5
Ronchetti, S.6
Crisafulli, C.7
Esposito, E.8
Caputi, A.P.9
Riccardi, C.10
-
31
-
-
33846022338
-
Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation
-
DOI 10.1096/fj.06-6611com
-
Cuzzocrea S, Ronchetti S, Genovese T, Mazzon E, Agostini M, Di Paola R, et al,. (2007). Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation. FASEB J 21: 117-129. (Pubitemid 46052551)
-
(2007)
FASEB Journal
, vol.21
, Issue.1
, pp. 117-129
-
-
Cuzzocrea, S.1
Ronchetti, S.2
Genovese, T.3
Mazzon, E.4
Agostini, M.5
Di Paola, R.6
Esposito, E.7
Muia, C.8
Nocentini, G.9
Riccardi, C.10
-
32
-
-
58149237000
-
Co-immunization of mice with a retroviral DNA vaccine and GITRL-encoding plasmid augments vaccine-induced protection against retrovirus infection
-
Dittmer U, Werner T, Kraft AR, (2008). Co-immunization of mice with a retroviral DNA vaccine and GITRL-encoding plasmid augments vaccine-induced protection against retrovirus infection. Viral Immunol 21: 459-467.
-
(2008)
Viral Immunol
, vol.21
, pp. 459-467
-
-
Dittmer, U.1
Werner, T.2
Kraft, A.R.3
-
33
-
-
20444398182
-
Glucocorticoid-induced TNF receptor, a costimulatory receptor on naive and activated T cells, uses TNF receptor-associated factor 2 in a novel fashion as an inhibitor of NF-κB activation
-
Esparza EM, Arch RH, (2005). Glucocorticoid-induced TNF receptor, a costimulatory receptor on naive and activated T cells, uses TNF receptor-associated factor 2 in a novel fashion as an inhibitor of NF-kappa B activation. J Immunol 174: 7875-7882. (Pubitemid 40806297)
-
(2005)
Journal of Immunology
, vol.174
, Issue.12
, pp. 7875-7882
-
-
Esparza, E.M.1
Arch, R.H.2
-
34
-
-
80052029220
-
GITR gene deletion and GITR-Fc soluble protein administration inhibit multiple organ failure induced by zymosan
-
Galuppo M, Nocentini G, Mazzon E, Ronchetti S, Esposito E, Riccardi L, et al,. (2011a). GITR gene deletion and GITR-Fc soluble protein administration inhibit multiple organ failure induced by zymosan. Shock 36: 263-271.
-
(2011)
Shock
, vol.36
, pp. 263-271
-
-
Galuppo, M.1
Nocentini, G.2
Mazzon, E.3
Ronchetti, S.4
Esposito, E.5
Riccardi, L.6
-
35
-
-
79551480227
-
The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice
-
Galuppo M, Nocentini G, Mazzon E, Ronchetti S, Esposito E, Riccardi L, et al,. (2011b). The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice. Br J Pharmacol 162: 1186-1201.
-
(2011)
Br J Pharmacol
, vol.162
, pp. 1186-1201
-
-
Galuppo, M.1
Nocentini, G.2
Mazzon, E.3
Ronchetti, S.4
Esposito, E.5
Riccardi, L.6
-
36
-
-
61349083564
-
Identification of regulatory T cells in systemic lupus erythematosus
-
Gerli R, Nocentini G, Alunno A, Bocci EB, Bianchini R, Bistoni O, et al,. (2009). Identification of regulatory T cells in systemic lupus erythematosus. Autoimmun Rev 8: 426-430.
-
(2009)
Autoimmun Rev
, vol.8
, pp. 426-430
-
-
Gerli, R.1
Nocentini, G.2
Alunno, A.3
Bocci, E.B.4
Bianchini, R.5
Bistoni, O.6
-
37
-
-
34249725559
-
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
-
DOI 10.1038/nm1563, PII NM1563
-
Grohmann U, Volpi C, Fallarino F, Bozza S, Bianchi R, Vacca C, et al,. (2007). Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy. Nat Med 13: 579-586. (Pubitemid 46828479)
-
(2007)
Nature Medicine
, vol.13
, Issue.5
, pp. 579-586
-
-
Grohmann, U.1
Volpi, C.2
Fallarino, F.3
Bozza, S.4
Bianchi, R.5
Vacca, C.6
Orabona, C.7
Belladonna, M.L.8
Ayroldi, E.9
Nocentini, G.10
Boon, L.11
Bistoni, F.12
Fioretti, M.C.13
Romani, L.14
Riccardi, C.15
Puccetti, P.16
-
38
-
-
79951949459
-
Gene expression analysis of HUVEC in response to TF-binding
-
Grosser M, Magdolen V, Baretton G, Luther T, Albrecht S, (2011). Gene expression analysis of HUVEC in response to TF-binding. Thromb Res 127: 259-263.
-
(2011)
Thromb Res
, vol.127
, pp. 259-263
-
-
Grosser, M.1
Magdolen, V.2
Baretton, G.3
Luther, T.4
Albrecht, S.5
-
39
-
-
0033602151
-
Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR
-
DOI 10.1016/S0960-9822(99)80093-1
-
Gurney AL, Marsters SA, Huang RM, Pitti RM, Mark DT, Baldwin DT, et al,. (1999). Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR. Curr Biol 9: 215-218. (Pubitemid 29120387)
-
(1999)
Current Biology
, vol.9
, Issue.4
, pp. 215-218
-
-
Gurney, A.L.1
Marsters, S.A.2
Huang, A.3
Pitti, R.M.4
Mark, M.5
Baldwin, D.T.6
Gray, A.M.7
Dowd, P.8
Brush, J.9
Heldens, S.10
Schow, P.11
Goddard, A.D.12
Wood, W.I.13
Baker, K.P.14
Godowski, P.J.15
Ashkenazi, A.16
-
40
-
-
77951886063
-
Therapeutic glucocorticoid-induced TNF receptor-mediated amplification of CD4+ T cell responses enhances antiparasitic immunity
-
Haque A, Stanley AC, Amante FH, Rivera Fde L, Zhou Y, Kuns RD, et al,. (2010). Therapeutic glucocorticoid-induced TNF receptor-mediated amplification of CD4+ T cell responses enhances antiparasitic immunity. J Immunol 184: 2583-2592.
-
(2010)
J Immunol
, vol.184
, pp. 2583-2592
-
-
Haque, A.1
Stanley, A.C.2
Amante, F.H.3
Rivera Fde, L.4
Zhou, Y.5
Kuns, R.D.6
-
41
-
-
2142771251
-
Phenotypic characterization of regulatory T cells in the human decidua
-
DOI 10.1111/j.1365-2249.2004.02441.x
-
Heikkinen J, Mottonen M, Alanen A, Lassila O, (2004). Phenotypic characterization of regulatory T cells in the human decidua. Clin Exp Immunol 136: 373-378. (Pubitemid 38543459)
-
(2004)
Clinical and Experimental Immunology
, vol.136
, Issue.2
, pp. 373-378
-
-
Heikkinen, J.1
Mottonen, M.2
Alanen, A.3
Lassila, O.4
-
42
-
-
77956832325
-
GITR ligand-mediated local expansion of regulatory T cells and immune privilege of corneal allografts
-
Hori J, Taniguchi H, Wang M, Oshima M, Azuma M, (2010). GITR ligand-mediated local expansion of regulatory T cells and immune privilege of corneal allografts. Invest Ophthalmol Vis Sic 51: 6556-6565.
-
(2010)
Invest Ophthalmol Vis Sic
, vol.51
, pp. 6556-6565
-
-
Hori, J.1
Taniguchi, H.2
Wang, M.3
Oshima, M.4
Azuma, M.5
-
43
-
-
38949172089
-
Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer
-
DOI 10.1158/1078-0432.CCR-07-0940
-
Hu P, Arias RS, Sadun RE, Nien YC, Zhang N, Sabzevari H, et al,. (2008). Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer. Clin Cancer Res 14: 579-588. (Pubitemid 351226128)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.2
, pp. 579-588
-
-
Hu, P.1
Arias, R.S.2
Sadun, R.E.3
Nien, Y.-C.4
Zhang, N.5
Sabzevari, H.6
Lutsiak, M.E.C.7
Khawli, L.A.8
Epstein, A.L.9
-
44
-
-
64849091216
-
The glucocorticoid-induced TNF receptor-related protein (GITR)-GITR ligand pathway acts as a mediator of cutaneous dendritic cell migration and promotes T cell-mediated acquired immunity
-
Kamimura Y, Iwai H, Piao J, Hashiguchi M, Azuma M, (2009). The glucocorticoid-induced TNF receptor-related protein (GITR)-GITR ligand pathway acts as a mediator of cutaneous dendritic cell migration and promotes T cell-mediated acquired immunity. J Immunol 182: 2708-2716.
-
(2009)
J Immunol
, vol.182
, pp. 2708-2716
-
-
Kamimura, Y.1
Iwai, H.2
Piao, J.3
Hashiguchi, M.4
Azuma, M.5
-
45
-
-
77951742201
-
Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival
-
Kim JI, Sonawane SB, Lee MK, Lee SH, Duff PE, Moore DJ, et al,. (2010). Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival. Eur J Immunol 40: 1369-1374.
-
(2010)
Eur J Immunol
, vol.40
, pp. 1369-1374
-
-
Kim, J.I.1
Sonawane, S.B.2
Lee, M.K.3
Lee, S.H.4
Duff, P.E.5
Moore, D.J.6
-
46
-
-
38449094242
-
Expression of AITR and AITR ligand in breast cancer patients
-
Kim YS, Jung HW, Choi J, Kwon BS, Ham SY, Jung AK, et al,. (2007). Expression of AITR and AITR ligand in breast cancer patients. Oncol Rep 18: 1189-1194.
-
(2007)
Oncol Rep
, vol.18
, pp. 1189-1194
-
-
Kim, Y.S.1
Jung, H.W.2
Choi, J.3
Kwon, B.S.4
Ham, S.Y.5
Jung, A.K.6
-
47
-
-
58149218516
-
The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells
-
Kober J, Leitner J, Klauser C, Woitek R, Majdic O, Stockl J, et al,. (2008). The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells. Eur J Immunol 38: 2678-2688.
-
(2008)
Eur J Immunol
, vol.38
, pp. 2678-2688
-
-
Kober, J.1
Leitner, J.2
Klauser, C.3
Woitek, R.4
Majdic, O.5
Stockl, J.6
-
48
-
-
1842424807
-
+ T Cell Activation and Experimental Autoimmune Encephalomyelitis
-
Kohm AP, Williams JS, Miller SD, (2004). Cutting edge: ligation of the glucocorticoid-induced TNF receptor enhances autoreactive CD4+ T cell activation and experimental autoimmune encephalomyelitis. J Immunol 172: 4686-4690. (Pubitemid 38456388)
-
(2004)
Journal of Immunology
, vol.172
, Issue.8
, pp. 4686-4690
-
-
Kohm, A.P.1
Williams, J.S.2
Miller, S.D.3
-
49
-
-
34247634525
-
GITR-GITRL system, a novel player in shock and inflammation
-
Krausz LT, Bianchini R, Ronchetti S, Fettucciari K, Nocentini G, Riccardi C, (2007). GITR-GITRL system, a novel player in shock and inflammation. ScientificWorldJournal 7: 533-566.
-
(2007)
ScientificWorldJournal
, vol.7
, pp. 533-566
-
-
Krausz, L.T.1
Bianchini, R.2
Ronchetti, S.3
Fettucciari, K.4
Nocentini, G.5
Riccardi, C.6
-
50
-
-
0033525904
-
Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand
-
DOI 10.1074/jbc.274.10.6056
-
Kwon B, Yu KY, Ni J, Yu GL, Jang IK, Kim YJ, et al,. (1999). Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand. J Biol Chem 274: 6056-6061. (Pubitemid 29111009)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.10
, pp. 6056-6061
-
-
Kwon, B.1
Yu, K.-Y.2
Ni, J.3
Yu, G.-L.4
Jang, I.-K.5
Kim, Y.-J.6
Xing, L.7
Liu, D.8
Wang, S.-X.9
Kwon, B.S.10
-
51
-
-
0037469673
-
Involvement of tumor necrosis factor receptor superfamily (TNFRSF) members in the pathogenesis of inflammatory diseases
-
Kwon B, Kim BS, Cho HR, Park JE, Kwon BS, (2003). Involvement of tumor necrosis factor receptor superfamily(TNFRSF) members in the pathogenesis of inflammatory diseases. Exp Mol Med 35: 8-16. (Pubitemid 36336923)
-
(2003)
Experimental and Molecular Medicine
, vol.35
, Issue.1
, pp. 8-16
-
-
Kwon, B.1
Kim, B.-S.2
Cho, H.R.3
Park, J.-E.4
Kwon, B.S.5
-
52
-
-
33847183114
-
Increase in circulating Foxp3+CD4+CD25(high) regulatory T cells in nasopharyngeal carcinoma patients
-
Lau KM, Cheng SH, Lo KW, Lee SA, Woo JK, Van Hasselt CA, et al,. (2007). Increase in circulating Foxp3+CD4+CD25(high) regulatory T cells in nasopharyngeal carcinoma patients. Br J Cancer 96: 617-622.
-
(2007)
Br J Cancer
, vol.96
, pp. 617-622
-
-
Lau, K.M.1
Cheng, S.H.2
Lo, K.W.3
Lee, S.A.4
Woo, J.K.5
Van Hasselt, C.A.6
-
53
-
-
33750882485
-
+ T cells
-
DOI 10.1111/j.1365-2567.2006.02459.x
-
Lee SK, Choi BK, Kim YH, Kang WJ, Kim KH, Sakaguchi S, et al,. (2006). Glucocorticoid-induced tumour necrosis factor receptor family-related receptor signalling exacerbates hapten-induced colitis by CD4+ T cells. Immunology 119: 479-487. (Pubitemid 44722210)
-
(2006)
Immunology
, vol.119
, Issue.4
, pp. 479-487
-
-
Lee, S.K.1
Choi, B.K.2
Kim, Y.H.3
Kang, W.J.4
Kim, K.H.5
Sakaguchi, S.6
Suh, J.H.7
Kim, T.Y.8
Kwon, B.S.9
-
54
-
-
0037131969
-
+ T suppressor cell clones produce transforming growth factor β, but not interleukin 10, and are distinct from type 1 T regulatory cells
-
DOI 10.1084/jem.20021139
-
Levings MK, Sangregorio R, Sartirana C, Moschin AL, Battaglia M, Orban PC, et al,. (2002). Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J Exp Med 196: 1335-1346. (Pubitemid 35375552)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.10
, pp. 1335-1346
-
-
Levings, M.K.1
Sangregorio, R.2
Sartirana, C.3
Moschin, A.L.4
Battaglia, M.5
Orban, P.C.6
Roncarolo, M.-G.7
-
55
-
-
77954056473
-
GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells
-
Liao G, Nayak S, Regueiro JR, Berger SB, Detre C, Romero X, et al,. (2010). GITR engagement preferentially enhances proliferation of functionally competent CD4+CD25+FoxP3+ regulatory T cells. Int Immunol 22: 259-270.
-
(2010)
Int Immunol
, vol.22
, pp. 259-270
-
-
Liao, G.1
Nayak, S.2
Regueiro, J.R.3
Berger, S.B.4
Detre, C.5
Romero, X.6
-
56
-
-
43749101844
-
Glucocorticoid-induced tumor necrosis factor receptor negatively regulates activation of human primary natural killer (NK) cells by blocking proliferative signals and increasing NK cell apoptosis
-
Liu B, Li Z, Mahesh SP, Pantanelli S, Hwang FS, Siu WO, et al,. (2008). Glucocorticoid-induced tumor necrosis factor receptor negatively regulates activation of human primary natural killer (NK) cells by blocking proliferative signals and increasing NK cell apoptosis. J Biol Chem 283: 8202-8210.
-
(2008)
J Biol Chem
, vol.283
, pp. 8202-8210
-
-
Liu, B.1
Li, Z.2
Mahesh, S.P.3
Pantanelli, S.4
Hwang, F.S.5
Siu, W.O.6
-
57
-
-
33747390484
-
Expression of GITR ligand abrogates immunosuppressive function of ocular tissue and differentially modulates inflammatory cytokines and chemokines
-
DOI 10.1002/eji.200635893
-
Mahesh SP, Li Z, Liu B, Fariss RN, Nussenblatt RB, (2006). Expression of GITR ligand abrogates immunosuppressive function of ocular tissue and differentially modulates inflammatory cytokines and chemokines. Eur J Immunol 36: 2128-2138. (Pubitemid 44251758)
-
(2006)
European Journal of Immunology
, vol.36
, Issue.8
, pp. 2128-2138
-
-
Mahesh, S.P.1
Li, Z.2
Liu, B.3
Fariss, R.N.4
Nussenblat, R.B.5
-
58
-
-
43649096023
-
Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation
-
Mahic M, Henjum K, Yaqub S, Bjornbeth BA, Torgersen KM, Tasken K, et al,. (2008). Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation. Eur J Immunol 38: 640-646.
-
(2008)
Eur J Immunol
, vol.38
, pp. 640-646
-
-
Mahic, M.1
Henjum, K.2
Yaqub, S.3
Bjornbeth, B.A.4
Torgersen, K.M.5
Tasken, K.6
-
59
-
-
77955665522
-
Clinical implication of peripheral CD4+CD25+ regulatory T cells and Th17 cells in myasthenia gravis patients
-
Masuda M, Matsumoto M, Tanaka S, Nakajima K, Yamada N, Ido N, et al,. (2010). Clinical implication of peripheral CD4+CD25+ regulatory T cells and Th17 cells in myasthenia gravis patients. J Neuroimmunol 225: 123-131.
-
(2010)
J Neuroimmunol
, vol.225
, pp. 123-131
-
-
Masuda, M.1
Matsumoto, M.2
Tanaka, S.3
Nakajima, K.4
Yamada, N.5
Ido, N.6
-
60
-
-
78650294948
-
New B-cell CD molecules
-
Matesanz-Isabel J, Sintes J, Llinas L, de Salort J, Lazaro A, Engel P, (2011). New B-cell CD molecules. Immunol Lett 134: 104-112.
-
(2011)
Immunol Lett
, vol.134
, pp. 104-112
-
-
Matesanz-Isabel, J.1
Sintes, J.2
Llinas, L.3
De Salort, J.4
Lazaro, A.5
Engel, P.6
-
61
-
-
31344475820
-
+ T-cell-mediated tolerance to experimental autoimmune thyroiditis by glucocorticoid-induced tumor necrosis factor receptor monoclonal antibody
-
DOI 10.1016/j.jaut.2005.09.003, PII S0896841105001095
-
Morris GP, Kong YC, (2006). Interference with CD4+CD25+ T-cell-mediated tolerance to experimental autoimmune thyroiditis by glucocorticoid-induced tumor necrosis factor receptor monoclonal antibody. J Autoimmun 26: 24-31. (Pubitemid 43138889)
-
(2006)
Journal of Autoimmunity
, vol.26
, Issue.1
, pp. 24-31
-
-
Morris, G.P.1
Kong, Y.-C.M.2
-
62
-
-
31844439923
-
Killed Candida albicans yeasts and hyphae inhibit gamma interferon release by murine natural killer cells
-
DOI 10.1128/IAI.74.2.1403-1406.2006
-
Murciano C, Villamon E, O'Connor JE, Gozalbo D, Gil ML, (2006). Killed Candida albicans yeasts and hyphae inhibit gamma interferon release by murine natural killer cells. Infect Immun 74: 1403-1406. (Pubitemid 43185583)
-
(2006)
Infection and Immunity
, vol.74
, Issue.2
, pp. 1403-1406
-
-
Murciano, C.1
Villamon, E.2
O'Connor, J.-E.3
Gozalbo, D.4
Gil, M.L.5
-
63
-
-
57449111487
-
In vivo expansion of CD4+Foxp3+ regulatory T cells mediated by GITR molecules
-
Nishioka T, Nishida E, Iida R, Morita A, Shimizu J, (2008). In vivo expansion of CD4+Foxp3+ regulatory T cells mediated by GITR molecules. Immunol Lett 121: 97-104.
-
(2008)
Immunol Lett
, vol.121
, pp. 97-104
-
-
Nishioka, T.1
Nishida, E.2
Iida, R.3
Morita, A.4
Shimizu, J.5
-
64
-
-
77951128998
-
GITR: A modulator of immune response and inflammation
-
Nocentini G, Riccardi C, (2009). GITR: a modulator of immune response and inflammation. Adv Exp Med Biol 647: 156-173.
-
(2009)
Adv Exp Med Biol
, vol.647
, pp. 156-173
-
-
Nocentini, G.1
Riccardi, C.2
-
65
-
-
0030962132
-
A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis
-
DOI 10.1073/pnas.94.12.6216
-
Nocentini G, Giunchi L, Ronchetti S, Krausz LT, Bartoli A, Moraca R, et al,. (1997). A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis. Proc Natl Acad Sci U S A 94: 6216-6221. (Pubitemid 27270664)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.12
, pp. 6216-6221
-
-
Nocentini, G.1
Giunchi, L.2
Ronchetti, S.3
Krausz, L.T.4
Bartoli, A.5
Moraca, R.6
Migliorati, G.7
Riccardi, C.8
-
66
-
-
44249089994
-
Glucocorticoid-induced tumor necrosis factor receptor-related (GITR)-Fc fusion protein inhibits GITR triggering and protects from the inflammatory response after spinal cord injury
-
DOI 10.1124/mol.107.044354
-
Nocentini G, Cuzzocrea S, Genovese T, Bianchini R, Mazzon E, Ronchetti S, et al,. (2008). Glucocorticoid-induced tumor necrosis factor receptor-related (GITR)-Fc fusion protein inhibits GITR triggering and protects from the inflammatory response after spinal cord injury. Mol Pharmacol 73: 1610-1621. (Pubitemid 351724350)
-
(2008)
Molecular Pharmacology
, vol.73
, Issue.6
, pp. 1610-1621
-
-
Nocentini, G.1
Cuzzocrea, S.2
Genovese, T.3
Bianchini, R.4
Mazzon, E.5
Ronchetti, S.6
Esposito, E.7
Rosanna, D.P.8
Bramanti, P.9
Riccardi, C.10
-
67
-
-
38649096319
-
NGF-promoted axon growth and target innervation requires GITRL-GITR signaling
-
DOI 10.1038/nn2034, PII NN2034
-
O'Keeffe GW, Gutierrez H, Pandolfi PP, Riccardi C, Davies AM, (2008). NGF-promoted axon growth and target innervation requires GITRL-GITR signaling. Nat Neurosci 11: 135-142. (Pubitemid 351170494)
-
(2008)
Nature Neuroscience
, vol.11
, Issue.2
, pp. 135-142
-
-
O'Keeffe, G.W.1
Gutierrez, H.2
Pandolfi, P.P.3
Riccardi, C.4
Davies, A.M.5
-
68
-
-
67649198525
-
GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo
-
Van Olffen RW, Koning N, Van Gisbergen KP, Wensveen FM, Hoek RM, Boon L, et al,. (2009). GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo. J Immunol 182: 7490-7500.
-
(2009)
J Immunol
, vol.182
, pp. 7490-7500
-
-
Van Olffen, R.W.1
Koning, N.2
Van Gisbergen, K.P.3
Wensveen, F.M.4
Hoek, R.M.5
Boon, L.6
-
69
-
-
29744441207
-
Glucocorticoid-induced TNFR family-related protein (GITR) activation exacerbates murine asthma and collagen-induced arthritis
-
DOI 10.1002/eji.200535421
-
Patel M, Xu D, Kewin P, Choo-Kang B, McSharry C, Thomson NC, et al,. (2005). Glucocorticoid-induced TNFR family-related protein (GITR) activation exacerbates murine asthma and collagen-induced arthritis. Eur J Immunol 35: 3581-3590. (Pubitemid 43025538)
-
(2005)
European Journal of Immunology
, vol.35
, Issue.12
, pp. 3581-3590
-
-
Patel, M.1
Xu, D.2
Kewin, P.3
Choo-Kang, B.4
McSharry, C.5
Thompson, N.C.6
Liew, F.Y.7
-
70
-
-
77955373324
-
T cell inflammatory response, Foxp3 and TNFRS18-L regulation of peripheral blood mononuclear cells from patients with nasal polyps-asthma after staphylococcal superantigen stimulation
-
Perez Novo CA, Jedrzejczak-Czechowicz M, Lewandowska-Polak A, Claeys C, Holtappels G, Van Cauwenberge P, et al,. (2010). T cell inflammatory response, Foxp3 and TNFRS18-L regulation of peripheral blood mononuclear cells from patients with nasal polyps-asthma after staphylococcal superantigen stimulation. Clin Exp Allergy 40: 1323-1332.
-
(2010)
Clin Exp Allergy
, vol.40
, pp. 1323-1332
-
-
Perez Novo, C.A.1
Jedrzejczak-Czechowicz, M.2
Lewandowska-Polak, A.3
Claeys, C.4
Holtappels, G.5
Van Cauwenberge, P.6
-
71
-
-
67650490302
-
Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours
-
Piao J, Kamimura Y, Iwai H, Cao Y, Kikuchi K, Hashiguchi M, et al,. (2009). Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours. Immunology 127: 489-499.
-
(2009)
Immunology
, vol.127
, pp. 489-499
-
-
Piao, J.1
Kamimura, Y.2
Iwai, H.3
Cao, Y.4
Kikuchi, K.5
Hashiguchi, M.6
-
72
-
-
78349278492
-
Glucocorticoid-induced TNFR-related (GITR) protein and its ligand in antitumor immunity: Functional role and therapeutic modulation
-
doi:10.1155/2010/239083.
-
Placke T, Kopp HG, Salih HR, (2010). Glucocorticoid-induced TNFR-related (GITR) protein and its ligand in antitumor immunity: functional role and therapeutic modulation. Clin Dev Immunol doi:10.1155/2010/239083.
-
(2010)
Clin Dev Immunol
-
-
Placke, T.1
Kopp, H.G.2
Salih, H.R.3
-
73
-
-
84858209818
-
Effect of the antimouse GITR mab plus chemotherapy on survival and tumor immunity
-
Ponte J, Doty D, Christmas R, Ponath P, Vaickus L, Rosenzweig M, (2010a). Effect of the antimouse GITR mab plus chemotherapy on survival and tumor immunity. J Clin Oncol 28: e13147.
-
(2010)
J Clin Oncol
, vol.28
-
-
Ponte, J.1
Doty, D.2
Christmas, R.3
Ponath, P.4
Vaickus, L.5
Rosenzweig, M.6
-
74
-
-
77952013354
-
Enhancement of humoral and cellular immunity with an anti-glucocorticoid- induced tumour necrosis factor receptor monoclonal antibody
-
Ponte JF, Ponath P, Gulati R, Slavonic M, Paglia M, O'Shea A, et al,. (2010b). Enhancement of humoral and cellular immunity with an anti-glucocorticoid-induced tumour necrosis factor receptor monoclonal antibody. Immunology 130: 231-242.
-
(2010)
Immunology
, vol.130
, pp. 231-242
-
-
Ponte, J.F.1
Ponath, P.2
Gulati, R.3
Slavonic, M.4
Paglia, M.5
O'Shea, A.6
-
75
-
-
77956030368
-
A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development
-
Poulton LD, Nolan KF, Anastasaki C, Waldmann H, Patton EE, (2010). A novel role for Glucocorticoid-Induced TNF Receptor Ligand (Gitrl) in early embryonic zebrafish development. Int J Dev Biol 54: 815-825.
-
(2010)
Int J Dev Biol
, vol.54
, pp. 815-825
-
-
Poulton, L.D.1
Nolan, K.F.2
Anastasaki, C.3
Waldmann, H.4
Patton, E.E.5
-
76
-
-
33646876477
-
Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity
-
Ramirez-Montagut T, Chow A, Hirschhorn-Cymerman D, Terwey TH, Kochman AA, Lu S, et al,. (2006). Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity. J Immunol 176: 6434-6442. (Pubitemid 43787825)
-
(2006)
Journal of Immunology
, vol.176
, Issue.11
, pp. 6434-6442
-
-
Ramirez-Montagut, T.1
Chow, A.2
Hirschhorn-Cymerman, D.3
Terwey, T.H.4
Kochman, A.A.5
Lu, S.6
Miles, R.C.7
Sakaguchi, S.8
Houghton, A.N.9
Van Den Brink, M.R.M.10
-
77
-
-
0036660176
-
Role of GITR in activation response of T lymphocytes
-
DOI 10.1182/blood-2001-12-0276
-
Ronchetti S, Nocentini G, Riccardi C, Pandolfi PP, (2002). Role of GITR in activation response of T lymphocytes. Blood 100: 350-352. (Pubitemid 35177469)
-
(2002)
Blood
, vol.100
, Issue.1
, pp. 350-352
-
-
Ronchetti, S.1
Nocentini, G.2
Riccardi, C.3
Pandolfi, P.P.4
-
78
-
-
38449114329
-
Glucocorticoid-induced TNFR-related protein lowers the threshold of CD28 costimulation in CD8+ T cells
-
Ronchetti S, Nocentini G, Bianchini R, Krausz LT, Migliorati G, Riccardi C, (2007). Glucocorticoid-induced TNFR-related protein lowers the threshold of CD28 costimulation in CD8+ T cells. J Immunol 179: 5916-5926.
-
(2007)
J Immunol
, vol.179
, pp. 5916-5926
-
-
Ronchetti, S.1
Nocentini, G.2
Bianchini, R.3
Krausz, L.T.4
Migliorati, G.5
Riccardi, C.6
-
79
-
-
78751705229
-
Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity
-
Ronchetti S, Nocentini G, Petrillo MG, Bianchini R, Sportoletti P, Bastianelli A, et al,. (2011). Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity. Immunol Lett 135: 24-33.
-
(2011)
Immunol Lett
, vol.135
, pp. 24-33
-
-
Ronchetti, S.1
Nocentini, G.2
Petrillo, M.G.3
Bianchini, R.4
Sportoletti, P.5
Bastianelli, A.6
-
80
-
-
79952753759
-
Development of TRX518, an aglycosyl humanized monoclonal antibody (Mab) agonist of huGITR
-
abstract e13028.
-
Rosenzweig M, Ponte J, Apostolou I, Doty D, Guild J, Slavonic M, et al,. (2010). Development of TRX518, an aglycosyl humanized monoclonal antibody (Mab) agonist of huGITR. J Clin Oncol 28: abstract e13028.
-
(2010)
J Clin Oncol
, vol.28
-
-
Rosenzweig, M.1
Ponte, J.2
Apostolou, I.3
Doty, D.4
Guild, J.5
Slavonic, M.6
-
81
-
-
33846011898
-
GITR modulates innate and adaptive mucosal immunity during the development of experimental colitis in mice
-
DOI 10.1136/gut.2006.091181
-
Santucci L, Agostini M, Bruscoli S, Mencarelli A, Ronchetti S, Ayroldi E, et al,. (2007). GITR modulates innate and adaptive mucosal immunity during the development of experimental colitis in mice. Gut 56: 52-60. (Pubitemid 46044889)
-
(2007)
Gut
, vol.56
, Issue.1
, pp. 52-60
-
-
Santucci, L.1
Agostini, M.2
Bruscoli, S.3
Mencarelli, A.4
Ronchetti, S.5
Ayroldi, E.6
Morelli, A.7
Baldoni, M.8
Riccardi, C.9
-
82
-
-
58149337013
-
Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-beta
-
Satoguina JS, Adjobimey T, Arndts K, Hoch J, Oldenburg J, Layland LE, et al,. (2008). Tr1 and naturally occurring regulatory T cells induce IgG4 in B cells through GITR/GITR-L interaction, IL-10 and TGF-beta. Eur J Immunol 38: 3101-3113.
-
(2008)
Eur J Immunol
, vol.38
, pp. 3101-3113
-
-
Satoguina, J.S.1
Adjobimey, T.2
Arndts, K.3
Hoch, J.4
Oldenburg, J.5
Layland, L.E.6
-
83
-
-
79952770456
-
Anti-GITR antibodies-potential clinical applications for tumor immunotherapy
-
Schaer DA, Cohen AD, Wolchok JD, (2010). Anti-GITR antibodies-potential clinical applications for tumor immunotherapy. Curr Opin Investig Drugs 11: 1378-1386.
-
(2010)
Curr Opin Investig Drugs
, vol.11
, pp. 1378-1386
-
-
Schaer, D.A.1
Cohen, A.D.2
Wolchok, J.D.3
-
84
-
-
8844263805
-
- T suppressor cells
-
DOI 10.1016/j.humimm.2004.09.004, PII S019888590400624X
-
Scotto L, Naiyer AJ, Galluzzo S, Rossi P, Manavalan JS, Kim-Schulze S, et al,. (2004). Overlap between molecular markers expressed by naturally occurring CD4+CD25+ regulatory T cells and antigen specific CD4+CD25+ and CD8+CD28- T suppressor cells. Hum Immunol 65: 1297-1306. (Pubitemid 39535293)
-
(2004)
Human Immunology
, vol.65
, Issue.11
, pp. 1297-1306
-
-
Scotto, L.1
Naiyer, A.J.2
Galluzzo, S.3
Rossi, P.4
Manavalan, J.S.5
Kim-Schulze, S.6
Fang, J.7
Favera, R.D.8
Cortesini, R.9
Suciu-Foca, N.10
-
85
-
-
0036170938
-
+ regulatory T cells through GITR breaks immunological self-tolerance
-
DOI 10.1038/ni759
-
Shimizu J, Yamazaki S, Takahashi T, Ishida Y, Sakaguchi S, (2002). Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 3: 135-142. (Pubitemid 34141443)
-
(2002)
Nature Immunology
, vol.3
, Issue.2
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
86
-
-
18144395471
-
Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappaB ligand (RANKL) in osteoclast cells
-
Shin HH, Kim SJ, Lee DS, Choi HS, (2005). Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-kappaB ligand (RANKL) in osteoclast cells. Bone 36: 832-839.
-
(2005)
Bone
, vol.36
, pp. 832-839
-
-
Shin, H.H.1
Kim, S.J.2
Lee, D.S.3
Choi, H.S.4
-
87
-
-
78650668092
-
CD8 T cell-intrinsic GITR is required for T cell clonal expansion and mouse survival following severe influenza infection
-
Snell LM, McPherson AJ, Lin GH, Sakaguchi S, Pandolfi PP, Riccardi C, et al,. (2010). CD8 T cell-intrinsic GITR is required for T cell clonal expansion and mouse survival following severe influenza infection. J Immunol 185: 7223-7234.
-
(2010)
J Immunol
, vol.185
, pp. 7223-7234
-
-
Snell, L.M.1
McPherson, A.J.2
Lin, G.H.3
Sakaguchi, S.4
Pandolfi, P.P.5
Riccardi, C.6
-
88
-
-
73849110532
-
GITR blockade facilitates treg mediated allograft survival
-
Sonawane SB, Kim JI, Lee MK, Lee SH, Duff PE, Moore DJ, et al,. (2009). GITR blockade facilitates treg mediated allograft survival. Transplantation 88: 1169-1177.
-
(2009)
Transplantation
, vol.88
, pp. 1169-1177
-
-
Sonawane, S.B.1
Kim, J.I.2
Lee, M.K.3
Lee, S.H.4
Duff, P.E.5
Moore, D.J.6
-
89
-
-
0036947870
-
GITR interacts with the pro-apoptotic protein Siva and induces apoptosis [3]
-
DOI 10.1038/sj.cdd.4401140
-
Spinicelli S, Nocentini G, Ronchetti S, Krausz LT, Bianchini R, Riccardi C, (2002). GITR interacts with the pro-apoptotic protein Siva and induces apoptosis. Cell Death Differ 9: 1382-1384. (Pubitemid 36097709)
-
(2002)
Cell Death and Differentiation
, vol.9
, Issue.12
, pp. 1382-1384
-
-
Spinicelli, S.1
Nocentini, G.2
Ronchetti, S.3
Krausz, L.T.4
Bianchini, R.5
Riccardi, C.6
-
90
-
-
6344279933
-
+ T cells
-
Stephens GL, McHugh RS, Whitters MJ, Young DA, Luxenberg D, Carreno BM, et al,. (2004). Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells. J Immunol 173: 5008-5020. (Pubitemid 39387783)
-
(2004)
Journal of Immunology
, vol.173
, Issue.8
, pp. 5008-5020
-
-
Stephens, G.L.1
McHugh, R.S.2
Whitters, M.J.3
Young, D.A.4
Luxenberg, D.5
Carreno, B.M.6
Collins, M.7
Shevach, E.M.8
-
91
-
-
32444446901
-
Multimeric soluble CB40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines
-
DOI 10.1128/JVI.80.4.1762-1772.2006
-
Stone GW, Barzee S, Snarsky V, Kee K, Spina CA, Yu XF, et al,. (2006a). Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines. J Virol 80: 1762-1772. (Pubitemid 43228717)
-
(2006)
Journal of Virology
, vol.80
, Issue.4
, pp. 1762-1772
-
-
Stone, G.W.1
Barzee, S.2
Snarsky, V.3
Kee, K.4
Spina, C.A.5
Yu, X.-F.6
Kornbluth, R.S.7
-
92
-
-
34248635935
-
Macaque multimeric soluble CD40 ligand and GITR ligand constructs are immunostimulatory molecules in vitro
-
DOI 10.1128/CVI.00198-06
-
Stone GW, Barzee S, Snarsky V, Spina CA, Lifson JD, Pillai VK, et al,. (2006b). Macaque multimeric soluble CD40 ligand and GITR ligand constructs are immunostimulatory molecules in vitro. Clin Vaccine Immunol 13: 1223-1230. (Pubitemid 46768880)
-
(2006)
Clinical and Vaccine Immunology
, vol.13
, Issue.11
, pp. 1223-1230
-
-
Stone, G.W.1
Barzee, S.2
Snarsky, V.3
Spina, C.A.4
Lifson, J.D.5
Pillai, V.K.B.6
Amara, R.R.7
Villinger, F.8
Kornbluth, R.S.9
-
93
-
-
1642332369
-
Regulation of autoimmune diabetes by non-islet-specific T cells - A role for the glucocorticoid-induced TNF receptor
-
DOI 10.1002/eji.200324599
-
Suri A, Shimizu J, Katz JD, Sakaguchi S, Unanue ER, Kanagawa O, (2004). Regulation of autoimmune diabetes by non-islet-specific T cells-a role for the glucocorticoid-induced TNF receptor. Eur J Immunol 34: 447-454. (Pubitemid 39255955)
-
(2004)
European Journal of Immunology
, vol.34
, Issue.2
, pp. 447-454
-
-
Suri, A.1
Shimizu, J.2
Katz, J.D.3
Sakaguchi, S.4
Unanue, E.R.5
Kanagawa, O.6
-
94
-
-
0345598872
-
Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells
-
DOI 10.1073/pnas.2334901100
-
Tone M, Tone Y, Adams E, Yates SF, Frewin MR, Cobbold SP, et al,. (2003). Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proc Natl Acad Sci USA 100: 15059-15064. (Pubitemid 37518016)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.25
, pp. 15059-15064
-
-
Tone, M.1
Tone, Y.2
Adams, E.3
Yates, S.F.4
Frewin, M.R.5
Cobbold, S.P.6
Waldmann, H.7
-
95
-
-
34347396781
-
+ regulatory T cells
-
DOI 10.1189/jlb.0906568
-
Tuyaerts S, Van Meirvenne S, Bonehill A, Heirman C, Corthals J, Waldmann H, et al,. (2007). Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells. J Leukoc Biol 82: 93-105. (Pubitemid 47026420)
-
(2007)
Journal of Leukocyte Biology
, vol.82
, Issue.1
, pp. 93-105
-
-
Tuyaerts, S.1
Van Meirvenne, S.2
Bonehill, A.3
Heirman, C.4
Corthals, J.5
Waldmann, H.6
Breckpot, K.7
Thielemans, K.8
Aerts, J.L.9
-
96
-
-
27844470637
-
Cip1/WAF1 transcriptional target conferring resistance of keratinocytes to UV light-induced apoptosis
-
DOI 10.1074/jbc.M507976200
-
Wang J, Devgan V, Corrado M, Prabhu NS, El-Deiry WS, Riccardi C, et al,. (2005). Glucocorticoid-induced tumor necrosis factor receptor is a p21Cip1/WAF1 transcriptional target conferring resistance of keratinocytes to UV light-induced apoptosis. J Biol Chem 280: 37725-37731. (Pubitemid 41642381)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.45
, pp. 37725-37731
-
-
Wang, J.1
Devgan, V.2
Corrado, M.3
Prabhu, N.S.4
El-Deiry, W.S.5
Riccardi, C.6
Pandolfi, P.P.7
Missero, C.8
Dotto, G.P.9
-
97
-
-
68149156979
-
Trimer stabilization, oligomerization, and antibody-mediated cell surface immobilization improve the activity of soluble trimers of CD27L, CD40L, 41BBL, and glucocorticoid-induced TNF receptor ligand
-
Wyzgol A, Muller N, Fick A, Munkel S, Grigoleit GU, Pfizenmaier K, et al,. (2009). Trimer stabilization, oligomerization, and antibody-mediated cell surface immobilization improve the activity of soluble trimers of CD27L, CD40L, 41BBL, and glucocorticoid-induced TNF receptor ligand. J Immunol 183: 1851-1861.
-
(2009)
J Immunol
, vol.183
, pp. 1851-1861
-
-
Wyzgol, A.1
Muller, N.2
Fick, A.3
Munkel, S.4
Grigoleit, G.U.5
Pfizenmaier, K.6
-
98
-
-
70949096864
-
Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: A potential therapeutic target
-
You S, Poulton L, Cobbold S, Liu CP, Rosenzweig M, Ringler D, et al,. (2009). Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target. PLoS ONE 4: e7848.
-
(2009)
PLoS ONE
, vol.4
-
-
You, S.1
Poulton, L.2
Cobbold, S.3
Liu, C.P.4
Rosenzweig, M.5
Ringler, D.6
-
99
-
-
77958038643
-
Mature B cells are critical to T-cell-mediated tumor immunity induced by an agonist anti-GITR monoclonal antibody
-
Zhou P, Qiu J, L'Italien L, Gu D, Hodges D, Chao CC, et al,. (2010). Mature B cells are critical to T-cell-mediated tumor immunity induced by an agonist anti-GITR monoclonal antibody. J Immunother 33: 789-797.
-
(2010)
J Immunother
, vol.33
, pp. 789-797
-
-
Zhou, P.1
Qiu, J.2
L'Italien, L.3
Gu, D.4
Hodges, D.5
Chao, C.C.6
-
100
-
-
44449086793
-
Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states
-
DOI 10.1073/pnas.0711350105
-
Zhou Z, Song X, Berezov A, Zhang G, Li Y, Zhang H, et al,. (2008a). Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states. Proc Natl Acad Sci USA 105: 5465-5470. (Pubitemid 351753886)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.14
, pp. 5465-5470
-
-
Zhou, Z.1
Song, X.2
Berezov, A.3
Zhang, G.4
Li, Y.5
Zhang, H.6
Murali, R.7
Li, B.8
Greene, M.I.9
-
101
-
-
38649115316
-
Structural basis for ligand-mediated mouse GITR activation
-
DOI 10.1073/pnas.0711206105
-
Zhou Z, Tone Y, Song X, Furuuchi K, Lear JD, Waldmann H, et al,. (2008b). Structural basis for ligand-mediated mouse GITR activation. Proc Natl Acad Sci USA 105: 641-645. (Pubitemid 351171761)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.2
, pp. 641-645
-
-
Zhou, Z.1
Tone, Y.2
Song, X.3
Furuuchi, K.4
Lear, J.D.5
Waldmann, H.6
Tone, M.7
Greene, M.I.8
Murali, R.9
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