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Volumn 33, Issue 9, 2010, Pages 925-934

Tumor-specific crosslinking of GITR as costimulation for immunotherapy

Author keywords

costimulation; fibroblast activation protein; glucocorticoid induced tumor necrosis factor related receptor ligand; regulatory T cell

Indexed keywords

DIMER; FIBROBLAST ACTIVATING PROTEIN ANTIBODY GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RELATED RECEPTOR LIGAND FUSION PROTEIN; FIBROBLAST ACTIVATION PROTEIN; GAMMA INTERFERON; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; HYBRID PROTEIN; INTERLEUKIN 2; PROTEIN; UNCLASSIFIED DRUG;

EID: 78149284338     PISSN: 15249557     EISSN: None     Source Type: Journal    
DOI: 10.1097/CJI.0b013e3181f3cc87     Document Type: Article
Times cited : (15)

References (42)
  • 1
    • 34447277894 scopus 로고    scopus 로고
    • Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
    • Gao Q, Qiu SJ, Fan J, et al. Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection. J Clin Oncol. 2007;25:2586-2593.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 2586-2593
    • Gao, Q.1    Qiu, S.J.2    Fan, J.3
  • 2
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-949.
    • (2004) Nat. Med. , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 3
    • 29444442811 scopus 로고    scopus 로고
    • +/regulatory T-cell ratio are associated with favorable prognosis in ovarian cancer
    • +/regulatory T-cell ratio are associated with favorable prognosis in ovarian cancer. Proc Natl Acad Sci U S A. 2005;102:18538-18543.
    • (2005) Proc. Natl. Acad. Sci. U S A , vol.102 , pp. 18538-18543
    • Sato, E.1    Olson, S.H.2    Ahn, J.3
  • 4
    • 0030962132 scopus 로고    scopus 로고
    • A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T-cell receptor-induced apoptosis
    • Nocentini G, Giunchi L, Ronchetti S, et al. A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T-cell receptor-induced apoptosis. Proc Natl Acad Sci U S A. 1997;94:6216-6221.
    • (1997) Proc. Natl. Acad. Sci. U S A , vol.94 , pp. 6216-6221
    • Nocentini, G.1    Giunchi, L.2    Ronchetti, S.3
  • 5
    • 0036195161 scopus 로고    scopus 로고
    • CD4 (+) CD25 (+) immunoregulatory T cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh RS, Whitters MJ, Piccirillo CA, et al. CD4 (+) CD25 (+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity. 2002;16:311-323.
    • (2002) Immunity , vol.16 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3
  • 7
    • 0345598872 scopus 로고    scopus 로고
    • Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells
    • Tone M, Tone Y, Adams E, et al. Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells. Proc Natl Acad Sci U S A. 2003;100:15059-15064.
    • (2003) Proc. Natl. Acad. Sci. U S A , vol.100 , pp. 15059-15064
    • Tone, M.1    Tone, Y.2    Adams, E.3
  • 8
    • 1642379813 scopus 로고    scopus 로고
    • GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T-lymphocyte subpopulations
    • Ronchetti S, Zollo O, Bruscoli S, et al. GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T-lymphocyte subpopulations. Eur J Immunol. 2004;34:613-622.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 613-622
    • Ronchetti, S.1    Zollo, O.2    Bruscoli, S.3
  • 9
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25 (+) CD4 (+) regulatory T cells through GITR breaks immunological self-tolerance
    • Shimizu J, Yamazaki S, Takahashi T, et al. Stimulation of CD25 (+) CD4 (+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol. 2002;3:135-142.
    • (2002) Nat. Immunol. , vol.3 , pp. 135-142
    • Shimizu, J.1    Yamazaki, S.2    Takahashi, T.3
  • 11
    • 14744285671 scopus 로고    scopus 로고
    • +T cells blocks their inhibitory activity: A novel regulatory role for OX40 and its comparison with GITR
    • +T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR. Blood. 2005;105:2845-2851.
    • (2005) Blood , vol.105 , pp. 2845-2851
    • Valzasina, B.1    Guiducci, C.2    Dislich, H.3
  • 12
    • 38949172089 scopus 로고    scopus 로고
    • Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer
    • Hu P, Arias RS, Sadun RE, et al. Construction and preclinical characterization of Fc-mGITRL for the immunotherapy of cancer. Clin Cancer Res. 2008;14:579-588.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 579-588
    • Hu, P.1    Arias, R.S.2    Sadun, R.E.3
  • 13
    • 48649083285 scopus 로고    scopus 로고
    • +T cells induced by glucocorticoid-induced tumor necrosis factor receptor signaling
    • +T cells induced by glucocorticoid-induced tumor necrosis factor receptor signaling. Cancer Res. 2008;68:5948-5954.
    • (2008) Cancer Res. , vol.68 , pp. 5948-5954
    • Nishikawa, H.1    Kato, T.2    Hirayama, M.3
  • 14
    • 38849154553 scopus 로고    scopus 로고
    • +effector T cells in mediating agonistic anti-GITR mAb-induced-immune activation and tumor immunity in CT26 tumors
    • +effector T cells in mediating agonistic anti-GITR mAb-induced-immune activation and tumor immunity in CT26 tumors. J Immunol. 2007;179:7365-7375.
    • (2007) J. Immunol. , vol.179 , pp. 7365-7375
    • Zhou, P.1    L'Italien, L.2    Hodges, D.3
  • 17
    • 67650490302 scopus 로고    scopus 로고
    • Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours
    • Piao J, Kamimura Y, Iwai H, et al. Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours. Immunology. 2009;127:489-499.
    • (2009) Immunology , vol.127 , pp. 489-499
    • Piao, J.1    Kamimura, Y.2    Iwai, H.3
  • 19
    • 13444303994 scopus 로고    scopus 로고
    • Bypassing tumor-associated immune suppression with recombinant adenovirus constructs expressing membrane bound or secreted GITR-L
    • Calmels B, Paul S, Futin N, et al. Bypassing tumor-associated immune suppression with recombinant adenovirus constructs expressing membrane bound or secreted GITR-L. Cancer Gene Ther. 2005;12:198-205.
    • (2005) Cancer Gene Ther. , vol.12 , pp. 198-205
    • Calmels, B.1    Paul, S.2    Futin, N.3
  • 20
    • 33646419260 scopus 로고    scopus 로고
    • Agonist anti-GITR antibody enhances vaccine-induced CD8 (+) T-cell responses and tumor immunity
    • Cohen AD, Diab A, Perales MA, et al. Agonist anti-GITR antibody enhances vaccine-induced CD8 (+) T-cell responses and tumor immunity. Cancer Res. 2006;66:4904-4912.
    • (2006) Cancer Res. , vol.66 , pp. 4904-4912
    • Cohen, A.D.1    Diab, A.2    Perales, M.A.3
  • 21
    • 67649875392 scopus 로고    scopus 로고
    • Therapeutic immunity by adoptive tumor-primed CD4 (+) T-cell transfer in combination with in vivo GITR ligation
    • Liu Z, Tian S, Falo LD Jr, et al. Therapeutic immunity by adoptive tumor-primed CD4 (+) T-cell transfer in combination with in vivo GITR ligation. Mol Ther. 2009;17:1274-1281.
    • (2009) Mol. Ther. , vol.17 , pp. 1274-1281
    • Liu, Z.1    Tian, S.2    Falo Jr., L.D.3
  • 22
    • 0028286026 scopus 로고
    • Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers
    • Scanlan MJ, Raj BK, Calvo B, et al. Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers. Proc Natl Acad Sci U S A. 1994;91:5657-5661.
    • (1994) Proc. Natl. Acad. Sci. U S A , vol.91 , pp. 5657-5661
    • Scanlan, M.J.1    Raj, B.K.2    Calvo, B.3
  • 23
    • 23744458987 scopus 로고    scopus 로고
    • Characterization of cancer stroma markers: In silico analysis of an mRNA expression database for fibroblast activation protein and endosialin
    • Dolznig H, Schweifer N, Puri C, et al. Characterization of cancer stroma markers: in silico analysis of an mRNA expression database for fibroblast activation protein and endosialin. Cancer Immun. 2005;5:10.
    • (2005) Cancer Immun. , vol.5 , pp. 10
    • Dolznig, H.1    Schweifer, N.2    Puri, C.3
  • 24
    • 0025083528 scopus 로고
    • Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers
    • Garin-Chesa P, Old LJ, Rettig WJ. Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers. Proc Natl Acad Sci U S A. 1990;87:7235-7239.
    • (1990) Proc. Natl. Acad. Sci. U S A , vol.87 , pp. 7235-7239
    • Garin-Chesa, P.1    Old, L.J.2    Rettig, W.J.3
  • 25
    • 0027302568 scopus 로고
    • Regulation and heteromeric structure of the fibroblast activation protein in normal and transformed cells of mesenchymal and neuroecto-dermal origin
    • Rettig WJ, Garin-Chesa P, Healey JH, et al. Regulation and heteromeric structure of the fibroblast activation protein in normal and transformed cells of mesenchymal and neuroecto-dermal origin. Cancer Res. 1993;53:3327-3335.
    • (1993) Cancer Res. , vol.53 , pp. 3327-3335
    • Rettig, W.J.1    Garin-Chesa, P.2    Healey, J.H.3
  • 26
    • 70350542778 scopus 로고    scopus 로고
    • Fibroblast activation protein is expressed by rheumatoid myofibroblast-like syno-viocytes
    • Bauer S, Jendro MC, Wadle A, et al. Fibroblast activation protein is expressed by rheumatoid myofibroblast-like syno-viocytes. Arthritis Res Ther. 2006;8:R171.
    • (2006) Arthritis Res. Ther. , vol.8
    • Bauer, S.1    Jendro, M.C.2    Wadle, A.3
  • 27
    • 0033034717 scopus 로고    scopus 로고
    • Fibroblast activation protein: A cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis
    • Levy MT, McCaughan GW, Abbott CA, et al. Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis. Hepatology. 1999;29:1768-1778.
    • (1999) Hepatology , vol.29 , pp. 1768-1778
    • Levy, M.T.1    McCaughan, G.W.2    Abbott, C.A.3
  • 28
    • 0037989982 scopus 로고    scopus 로고
    • A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer
    • Scott AM, Wiseman G, Welt S, et al. A Phase I dose-escalation study of sibrotuzumab in patients with advanced or metastatic fibroblast activation protein-positive cancer. Clin Cancer Res. 2003;9:1639-1647.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1639-1647
    • Scott, A.M.1    Wiseman, G.2    Welt, S.3
  • 29
    • 0035407983 scopus 로고    scopus 로고
    • Species-crossreactive scFv against the tumor stroma marker "fibroblast activation protein" selected by phage display from an immunized FAP-/- knock-out mouse
    • Brocks B, Garin-Chesa P, Behrle E, et al. Species-crossreactive scFv against the tumor stroma marker "fibroblast activation protein" selected by phage display from an immunized FAP-/- knock-out mouse. Mol Med. 2001;7:461-469.
    • (2001) Mol. Med. , vol.7 , pp. 461-469
    • Brocks, B.1    Garin-Chesa, P.2    Behrle, E.3
  • 30
    • 0037102412 scopus 로고    scopus 로고
    • Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model
    • Cheng JD, Dunbrack RL Jr, Valianou M, et al. Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model. Cancer Res. 2002;62:4767-4772.
    • (2002) Cancer Res. , vol.62 , pp. 4767-4772
    • Cheng, J.D.1    Dunbrack Jr., R.L.2    Valianou, M.3
  • 31
    • 71649112051 scopus 로고    scopus 로고
    • Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry
    • Thiel M, Wolfs MJ, Bauer S, et al. Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry. Immunology. 2010;129:28-40.
    • (2010) Immunology , vol.129 , pp. 28-40
    • Thiel, M.1    Wolfs, M.J.2    Bauer, S.3
  • 32
    • 24644515759 scopus 로고    scopus 로고
    • In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology
    • Suvas S, Kim B, Sarangi PP, et al. In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology. J Virol. 2005;79:11935-11942.
    • (2005) J. Virol. , vol.79 , pp. 11935-11942
    • Suvas, S.1    Kim, B.2    Sarangi, P.P.3
  • 34
    • 12144287345 scopus 로고    scopus 로고
    • Functional impairment of CD8 (+) T cells by regulatory T cells during persistent retroviral infection
    • Dittmer U, He H, Messer RJ, et al. Functional impairment of CD8 (+) T cells by regulatory T cells during persistent retroviral infection. Immunity. 2004;20:293-303.
    • (2004) Immunity , vol.20 , pp. 293-303
    • Dittmer, U.1    He, H.2    Messer, R.J.3
  • 36
    • 2442429448 scopus 로고    scopus 로고
    • Cutting edge: The natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T-cell suppression
    • Ji HB, Liao G, Faubion WA, et al. Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T-cell suppression. J Immunol. 2004;172:5823-5827.
    • (2004) J. Immunol. , vol.172 , pp. 5823-5827
    • Ji, H.B.1    Liao, G.2    Faubion, W.A.3
  • 37
    • 33744944082 scopus 로고    scopus 로고
    • Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human
    • Bossen C, Ingold K, Tardivel A, et al. Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. J Biol Chem. 2006;281:13964-13971.
    • (2006) J. Biol. Chem. , vol.281 , pp. 13964-13971
    • Bossen, C.1    Ingold, K.2    Tardivel, A.3
  • 38
    • 37649005414 scopus 로고    scopus 로고
    • Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function
    • Chattopadhyay K, Ramagopal UA, Mukhopadhaya A, et al. Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function. Proc Natl Acad Sci U S A. 2007;104:19452-19457.
    • (2007) Proc. Natl. Acad. Sci. U S A , vol.104 , pp. 19452-19457
    • Chattopadhyay, K.1    Ramagopal, U.A.2    Mukhopadhaya, A.3
  • 39
    • 44449086793 scopus 로고    scopus 로고
    • Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states
    • Zhou Z, Song X, Berezov A, et al. Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states. Proc Natl Acad Sci U S A. 2008;105:5465-5470.
    • (2008) Proc. Natl. Acad. Sci. U S A , vol.105 , pp. 5465-5470
    • Zhou, Z.1    Song, X.2    Berezov, A.3
  • 40
    • 38649090326 scopus 로고    scopus 로고
    • Evolution of GITRL immune function: Murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily
    • Chattopadhyay K, Ramagopal UA, Brenowitz M, et al. Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily. Proc Natl Acad Sci U S A. 2008;105:635-640.
    • (2008) Proc. Natl. Acad. Sci. U S A , vol.105 , pp. 635-640
    • Chattopadhyay, K.1    Ramagopal, U.A.2    Brenowitz, M.3
  • 41
    • 0033602151 scopus 로고    scopus 로고
    • Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR
    • Gurney AL, Marsters SA, Huang RM, et al. Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR. Curr Biol. 1999;9:215-218.
    • (1999) Curr. Biol. , vol.9 , pp. 215-218
    • Gurney, A.L.1    Marsters, S.A.2    Huang, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.