Glucocorticoid-induced tumor necrosis factor receptor-related (GITR)-Fc fusion protein inhibits GITR triggering and protects from the inflammatory response after spinal cord injury

Molecular Pharmacology

Volumn 73, Issue 6, 2008, Pages 1610-1621

  Nocentini, Giuseppe ^a   Cuzzocrea, Salvatore ^b   Genovese, Tiziana ^c   Bianchini, Rodolfo ^a   Mazzon, Emanuela ^c   Ronchetti, Simona ^d   Esposito, Emanuela ^c   Rosanna, Di Paola ^c   Bramanti, Placido ^c   Riccardi, Carlo ^a  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

^c IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR RELATED FC FUSION PROTEIN; HYBRID PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; INTERLEUKIN 2; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; FEMALE; HISTOPATHOLOGY; KNOCKOUT MOUSE; LYMPHOCYTIC INFILTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD INJURY; T LYMPHOCYTE; WILD TYPE;

ANIMALS; CELLS, CULTURED; INFLAMMATION; INFLAMMATION MEDIATORS; MEMBRANE FUSION PROTEINS; MICE; MICE, MUTANT STRAINS; NEUROPROTECTIVE AGENTS; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; SPINAL CORD INJURIES; TIME FACTORS;

EID: 44249089994     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.107.044354     Document Type: Article

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