Various jobs of proteolytic enzymes in skeletal muscle during unloading: Facts and speculations

Journal of Biomedicine and Biotechnology

Volumn 2012, Issue , 2012, Pages

  Kachaeva, E V ^a   Shenkman, B S ^a  

^a INSTITUTE OF BIOMEDICAL PROBLEMS   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CASPASE 3; CASPASE 6; CASPASE 9; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MYOSTATIN; TRANSCRIPTION FACTOR FOXO; UBIQUITIN PROTEIN LIGASE E3; PEPTIDE HYDROLASE;

AUTOPHAGY; BONE ATROPHY; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; LYSOSOME; MUSCLE ATROPHY; MUSCLE DENERVATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SOLEUS MUSCLE; UBIQUITINATION; ANIMAL; ANIMAL MODEL; ENZYMOLOGY; IMMOBILIZATION; METABOLISM; PATHOLOGY;

ANIMALS; HINDLIMB SUSPENSION; HUMANS; MODELS, ANIMAL; MUSCLE, SKELETAL; MUSCULAR ATROPHY; PEPTIDE HYDROLASES;

EID: 84858147140     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2012/493618     Document Type: Review

References (134)

1. Thomason D. B., Booth F. W., Atrophy of the soleus muscle by hindlimb unweighting Journal of Applied Physiology 1990 68 1 1 12 (Pubitemid 20075203)
2. Caiozzo V. J., Plasticity of skeletal muscle phenotype: mechanical consequences Muscle and Nerve 2002 26 6 740 768 (Pubitemid 35424425)
3. Morey-Holton E. R., Globus R. K., Hindlimb unloading rodent model: technical aspects Journal of Applied Physiology 2002 92 4 1367 1377 (Pubitemid 34670888)
4. Yamashita-Goto K., Okuyama R., Honda M., Kawasaki K., Fujita K., Yamada T., Nonaka I., Ohira Y., Yoshioka T., Maximal and submaximal forces of slow fibers in human soleus after bed rest Journal of Applied Physiology 2001 91 1 417 424 (Pubitemid 32574752)
5. Stevens L., Mounier Y., Holy X., Falempin M., Contractile properties of rat soleus muscle after 15 days of hindlimb suspension Journal of Applied Physiology 1990 68 1 334 340 (Pubitemid 20075252)
6. Grigoriev A. I., Shenkman B. S., Skeletal muscle during unloading Vestn. Russ. Acad. Sci. In Russian 2008 78 4 337 345
7. Ponomareva E. V., Kravtsova V. V., Kachaeva E. V., Altaeva E. G., Vikhliantsev I. M., Podlubnaia Z. A., Krivo I. I., Shenkman B. S., Contractile properties of the isolated rat musculus soleus and single skinned soleus fibers at the early stage of gravitational unloading: facts and hypotheses Biofizika 2008 53 6 1087 1094
8. Templeton G. H., Padalino M., Manton J., Influence of suspension hypokinesia on rat soleus muscle Journal of Applied Physiology Respiratory Environmental and Exercise Physiology 1984 56 2 278 286 (Pubitemid 14143680)
9. Haddad F., Adams G. R., Bodell P. W., Baldwin K. M., Isometric resistance exercise fails to counteract skeletal muscle atrophy processes during the initial stages of unloading Journal of Applied Physiology 2006 100 2 433 441 (Pubitemid 43671592)
10. Grigoriev A. I., Kozlovskaia I. B., Shenkman B. S., The role of support afferents in organisation of the tonic muscle system Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 2004 90 5 508 521
11. Vandenburgh H., Chromiak J., Shansky J., del Tatto M., Lemaire J., Space travel directly induces skeletal muscle atrophy The FASEB Journal 1999 13 9 1031 1038 (Pubitemid 29249728)
12. Steffen J. M., Musacchia X. J., Spaceflight effects on adult rat muscle protein, nucleic acids, and amino acids American Journal of Physiology 1984 247 16 R728 R732
13. Jaspers S. R., Tischler M. E., Metabolism of amino acids by the atrophied soleus of tail-casted, suspended rats Muscle Nerve 1986 9 554 561
14. Zhang P., Yang M., Liu H., Li L., Chen X.,. Book of Abstracts of the 16th IAA Humans in Space Symposium, pp.53, 2007
15. Bodine S. C., Stitt T. N., Gonzalez M., Kline W. O., Stover G. L., Bauerlein R., Zlotchenko E., Scrimgeour A., Lawrence J. C., Glass D. J., Yancopoulos G. D., Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo Nature Cell Biology 2001 3 11 1014 1019 (Pubitemid 34428747)
16. Goldspink D. F., Morton A. J., Loughna P., Goldspink G., The effect of hypokinesia and hypodynamia on protein turnover and the growth of four skeletal muscles of the rat Pflugers Archiv European Journal of Physiology 1986 407 3 333 340 (Pubitemid 16055748)
17. Taillandier D., Aurousseau E., Meynial-Denis D., Bechet D., Ferrara M., Cottin P., Ducastaing A., Bigard X., Guezennec C. Y., Schmid H. P., Attaix D., Coordinate activation of lysosomal, Ca 2+ -activated and ATP-ubiquitin-dependent proteinases in the unweighted rat soleus muscle Biochemical Journal 1996 316 1 65 72
18. Urso M. L., Scrimgeour A. G., Chen Y. W., Thompson P. D., Clarkson P. M., Analysis of human skeletal muscle after 48 h immobilization reveals alterations in mRNA and protein for extracellular matrix components Journal of Applied Physiology 2006 101 4 1136 1148 (Pubitemid 44497558)
19. Ikemoto M., Nikawa T., Takeda S., Watanabe C., Kitano T., Baldwin K. M., Izumi R., Nonaka I., Towatari T., Teshima S., Rokutan K., Kishi K., Space shuttle flight (STS-90) enhances degradation of rat myosin heavy chain in association with activation of ubiquitin-proteasome pathway The FASEB Journal 2001 15 7 1279 1281
20. Enns D. L., Raastad T., Ugelstad I., Belcastro A. N., Calpain/calpastatin activities and substrate depletion patterns during hindlimb unweighting and reweighting in skeletal muscle European Journal of Applied Physiology 2007 100 4 445 455 (Pubitemid 46773994)
21. Tidball J. G., Spencer M. J., Expression of a calpastatin transgene slows muscle wasting and obviates changes in myosin isoform expression during murine muscle disuse Journal of Physiology 2002 545 3 819 828 (Pubitemid 36024422)
22. Goll D. E., Thompson V. F., Li H., Wei W., Cong J., The calpain system Physiological Reviews 2003 83 3 731 801 (Pubitemid 36828925)
23. Steffen J. M., Musacchia X. J., Disuse atrophy, plasma corticosterone, and muscle glucocorticoid receptor levels Aviation Space and Environmental Medicine 1987 58 10 996 1000
24. Thomason D. B., Herrick R. E., Surdyka D., Baldwin K. M., Time course of soleus muscle myosin expression during hindlimb suspension and recovery Journal of Applied Physiology 1987 63 1 130 137 (Pubitemid 17107136)
25. Martonosi A., de Boland A. R., Boland R., Vanderkooi J. M., Halpin R. A., The mechanism of Ca transport and the permeability of sarcoplasmic reticulum membranes Recent Advances in Studies on Cardiac Structure and Metabolism 1974 4 473 494
26. Verjovski-Almeida S., Inesi G., Rapid kinetics of calcium ion transport and ATPase activity in the sarcoplasmic reticulum of dystrophic muscle Biochimica et Biophysica Acta 1979 558 1 119 125 (Pubitemid 10194349)
27. Stevens L., Mounier Y., Ca 2+ movements in sarcoplasmic reticulum of rat soleus fibers after hindlimb suspension Journal of Applied Physiology 1992 72 5 1735 1740
28. Ingalls C. P., Warren G. L., Armstrong R. B., Intracellular Ca 2+ transients in mouse soleus muscle after hindlimb unloading and reloading Journal of Applied Physiology 1999 87 1 386 390 (Pubitemid 29330705)
29. Macintosh B., McComas A., Gardiner P., Skeletal Muscle: Form and Function 2005 Champaign, Ill, USA Human Kinetics
30. Mukhina A. M., Zhelezniakova A. V., Kitina I. N., Shenkman B. S., Nemirovskaia T. L., NFATc1 and slow-to-fast shift of myosin heavy chain isoforms under functional unloading of the rat m. soleus Biofizika 2006 51 5 918 923
31. Pierno S., Desaphy J. F., Liantonio A., De Bellis M., Bianco G., De Luca A., Frigeri A., Nicchia G. P., Svelto M., Léoty C., George A. L., Conte Camerino D., Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse Brain 2002 125 7 1510 1521 (Pubitemid 34755166)
32. Krivo I. I., Kravtsova V. V., Altaeva E. G., Kubasov I. V., Prokof'ev A. V., Drabkina T. M., Nikol'ski E. E., Shenkman B. S., Decrease in the electrogenic contribution of Na,K-ATPase and resting membrane potential as a possible mechanism of calcium ion accumulation in filaments of the rat musculus soleus subjected to the short-term gravity unloading Biofizika 2008 53 6 1051 1057
33. Zeman R. J., Kameyama T., Matsumoto K., Regulation of protein degradation in muscle by calcium. Evidence for enhanced nonlysosomal proteolysis associated with elevated cytosolic calcium The Journal of Biological Chemistry 1985 260 25 13619 13624 (Pubitemid 16233212)
34. Desmedt J. E., Hainaut K., Regulation of ionized calcium in the cytosol of muscle cells during rest: action of dantrolene on the sarcoplasmic reticulum The Journal of Physiology 1976 257 87 107
35. Rodemann H. P., Waxman L., Goldberg A. L., The stimulation of protein degradation in muscle by Ca 2+ is mediated by prostaglandin E2 and does not require the calcium-activated protease The Journal of Biological Chemistry 1982 257 15 8716 8723 (Pubitemid 12004192)
36. Garca Daz B. E., Gauthier S., Davies P. L., Ca 2+ dependency of calpain 3 (p94) activation Biochemistry 2006 45 11 3714 3722
37. Enns D. L., Belcastro A. N., Early activation and redistribution of calpain activity in skeletal muscle during hindlimb unweighting and reweighting Canadian Journal of Physiology and Pharmacology 2006 84 6 601 609 (Pubitemid 44605723)
38. Shenkman B. S., Nemirovskaya T. L., Calcium-dependent signaling mechanisms and soleus fiber remodeling under gravitational unloading Journal of Muscle Research and Cell Motility 2008 29 68 221 230
39. Ma X.-W., Li Q., Xu P.-T., Zhang L., Li H., Yu Z.-B., Tetanic contractions impair sarcomeric Z-disk of atrophic soleus muscle via calpain pathway Molecular and Cellular Biochemistry 2011 354 1-2 171 180
40. Lomonosova Y., Kalamkarov G. R., Bugrova A. E., Protective effect of L-arginin on soleus proteins under functional unloading Biochemistry 2011 76 5 571 580
41. Tidball J. G., Lavergne E., Lau K. S., Spencer M. J., Stull J. T., Wehling M., Mechanical loading regulates NOS expression and activity in developing and adult skeletal muscle American Journal of Physiology 1998 275 1 C260 C266
42. Moukhina A., Shenkman B., Blottner D., Nemirovskaya T., Lemesheva Y., Pttmann B., Kozlovskaya I., Effects of support stimulation on human soleus fiber characteristics during exposure to dry immersion Journal of Gravitational Physiology 2004 11 2 P137 P138
43. Sorimachi H., Kinbara K., Kimura S., Takahashi M., Ishiura S., Sasagawa N., Sorimachi N., Shimada H., Tagawa K., Maruyama K., Suzuki K., Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence The Journal of Biological Chemistry 1995 270 52 31158 31162 (Pubitemid 26012203)
44. Murphy R. M., Verburg E., Lamb G. D., Ca 2+ activation of diffusible and bound pools of -calpain in rat skeletal muscle The Journal of Physiology 2006 576 2 595 612 (Pubitemid 44490148)
45. Smith I. J., Dodd S. L., Calpain activation causes a proteasome-dependent increase in protein degradation and inhibits the Akt signalling pathway in rat diaphragm muscle Experimental Physiology 2007 92 3 561 573 (Pubitemid 46608406)
46. Laure L., Danile N., Suel L., Marchand S., Aubert S., Bourg N., Roudaut C., Duguez S., Bartoli M., Richard I., A new pathway encompassing calpain 3 and its newly identified substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-B pathway in skeletal muscle The FEBS Journal 2010 277 20 4322 4337
47. Miller M. K., Bang M. L., Witt C. C., Labeit D., Trombitas C., Watanabe K., Granzier H., McElhinny A. S., Gregorio C. C., Labeit S., The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules Journal of Molecular Biology 2003 333 5 951 964 (Pubitemid 37324498)
48. Litvinova K. S., Vikhlyantsev I. M., Kozlovskaya I. B., Podlubnaya Z. A., Shenkman B. S., Effects of artificial support stimulation on fiber and molecular characteristics of soleus muscle in men exposed to 7-day dry immersion Journal of Gravitational Physiology 2004 11 2 P131 P132
49. Lange S., Xiang F., Yakovenko A., Vihola A., Hackman P., Rostkova E., Kristensen J., Brandmeier B., Franzen G., Hedberg B., Gunnarsson L. G., Hughes S. M., Marchand S., Sejersen T., Richard I., Edstrm L., Ehler E., Udd B., Gautel M., Cell biology: the kinase domain of titin controls muscle gene expression and protein turnover Science 2005 308 5728 1599 1603 (Pubitemid 40807503)
50. Centner T., Yano J., Kimura E., McElhinny A. S., Pelin K., Witt C. C., Bang M. L., Trombitas K., Granzier H., Gregorio C. C., Sorimachi H., Labeit S., Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain Journal of Molecular Biology 2001 306 4 717 726 (Pubitemid 33027694)
51. Kandarian S. C., Stevenson E. J., Molecular events in skeletal muscle during disuse atrophy Exercise and Sport Sciences Reviews 2002 30 3 111 116 (Pubitemid 34787297)
52. Shenkman B. S., Nemirovskaya T. L., Belozerova I. N., Vikhlyantsev I. M., Matveeva O. A., Staroverova K. S., Podlubnaya Z. A., Effects of Ca 2+ -binding agent on unloaded rat soleus: muscle morphology and sarcomeric titin content European Space Agency 2002 501 107 108
53. Shenkman B. S., Litvinova K. S., Nemirovskaya T. L., Podlubnaya Z. A., Vikhlyantsev I. M., Kozlovskaya I. B., Afferent and peripheral control of muscle fiber properties during gravitational unloading Journal of Gravitational Physiology 2004 11 2 P111 P114
54. Goto K., Okuyama R., Honda M., Uchida H., Akema T., Ohira Y., Yoshioka T., Profiles of connectin (titin) in atrophied soleus muscle induced by unloading of rats Journal of Applied Physiology 2003 94 3 897 902 (Pubitemid 36232001)
55. Chang H., Zhang L., Xu P.-T., Li Q., Sheng J.-J., Wang Y.-Y., Chen Y., Zhang L.-N., Yu Z.-B., Nuclear translocation of calpain-2 regulates propensity toward apoptosis in cardiomyocytes of tail-suspended rats Journal of Cellular Biochemistry 2011 112 2 571 580
56. Hasselgren P. O., Fischer J. E., Counter-regulatory hormones and mechanisms in amino acid metabolism with special reference to the catabolic response in skeletal muscle Current Opinion in Clinical Nutrition and Metabolic Care 1999 2 1 9 14 (Pubitemid 129628620)
57. Jagoe R. T., Goldberg A. L., What do we really know about the ubiquitin-proteasome pathway in muscle atrophy? Current Opinion in Clinical Nutrition and Metabolic Care 2001 4 3 183 190 (Pubitemid 33682075)
58. Lecker S. H., Jagoe R. T., Gilbert A., Gomes M., Baracos V., Bailey J., Price S. R., Mitch W. E., Goldberg A. L., Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression The FASEB Journal 2004 18 1 39 51 (Pubitemid 38076464)
59. Gomes M. D., Lecker S. H., Jagoe R. T., Navon A., Goldberg A. L., Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy Proceedings of the National Academy of Sciences of the United States of America 2001 98 25 14440 14445 (Pubitemid 33121410)
60. Medina R., Wing S. S., Haas A., Goldberg A. L., Activation of the ubiquitin-ATP-dependent proteolytic system in skeletal muscle during fasting and denervation atrophy Biomedica Biochimica Acta 1991 50 46 347 356
61. McElhinny A. S., Perry C. N., Witt C. C., Labeit S., Gregorio C. C., Muscle-specific RING finger-2 (MURF-2) is important for microtubule, intermediate filament and sarcomeric M-line maintenance in striated muscle development Journal of Cell Science 2004 117 15 3175 3188 (Pubitemid 39139904)
62. Gregorio C. C., Perry C. N., Mcelhinny A. S., Functional properties of the titin/connectin-associated proteins, the muscle-specific RING finger proteins (MURFs), in striated muscle Journal of Muscle Research and Cell Motility 2005 26 68 389 400
63. Jones S. W., Hill R. J., Krasney P. A., O'Conner B., Peirce N., Greenhaff P. L., Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass The FASEB Journal 2004 18 9 1025 1027 (Pubitemid 39561513)
64. Tintignac L. A., Lagirand J., Batonnet S., Sirri V., Leibovitch M. P., Leibovitch S. A., Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase The Journal of Biological Chemistry 2005 280 4 2847 2856 (Pubitemid 40189393)
65. Lagirand-Cantaloube J., Offner N., Csibi A., Leibovitch M. P., Batonnet-Pichon S., Tintignac L. A., Segura C. T., Leibovitch S. A., The initiation factor eIF3-f is a major target for Atrogin1/MAFbx function in skeletal muscle atrophy The EMBO Journal 2008 27 8 1266 1276 (Pubitemid 351574748)
66. Kedar V., McDonough H., Arya R., Li H. H., Rockman H. A., Patterson C., Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin I Proceedings of the National Academy of Sciences of the United States of America 2004 101 52 18135 18140 (Pubitemid 40054086)
67. Clarke B. A., Drujan D., Willis M. S., Murphy L. O., Corpina R. A., Burova E., Rakhilin S. V., Stitt T. N., Patterson C., Latres E., Glass D. J., The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle Cell Metabolism 2007 6 5 376 385 (Pubitemid 350011998)
68. Allen D. L., Bandstra E. R., Harrison B. C., Thorng S., Stodieck L. S., Kostenuik P. J., Morony S., Lacey D. L., Hammond T. G., Leinwand L. L., Argraves W. S., Bateman T. A., Barth J. L., Effects of spaceflight on murine skeletal muscle gene expression Journal of Applied Physiology 2009 106 2 582 592
69. Phillips S. M., Glover E. I., Rennie M. J., Alterations of protein turnover underlying disuse atrophy in human skeletal muscle Journal of Applied Physiology 2009 107 3 645 654
70. Salanova M., Schiffl G., Pttmann B., Schoser B. G., Blottner D., Molecular biomarkers monitoring human skeletal muscle fibres and microvasculature following long-term bed rest with and without countermeasures Journal of Anatomy 2008 212 3 306 318 (Pubitemid 351325486)
71. Ogawa T., Furochi H., Mameoka M., Hirasaka K., Onishi Y., Suzue N., Oarada M., Akamatsu M., Akima H., Fukunaga T., Kishi K., Yasui N., Ishidoh K., Fukuoka H., Nikawa T., Ubiquitin ligase gene expression in healthy volunteers with 20-day bedrest Muscle and Nerve 2006 34 4 463 469 (Pubitemid 44506715)
72. Reich K. A., Chen Y. W., Thompson P. D., Hoffman E. P., Clarkson P. M., Forty-eight hours of unloading and 24 h of reloading lead to changes in global gene expression patterns related to ubiquitination and oxidative stress in humans Journal of Applied Physiology 2010 109 5 1404 1415
73. Tesch P. A., von Walden F., Gustafsson T., Linnehan R. M., Trappe T. A., Skeletal muscle proteolysis in response to short-term unloading in humans Journal of Applied Physiology 2008 105 3 902 906
74. de Boer M. D., Selby A., Atherton P., Smith K., Seynnes O. R., Maganaris C. N., Maffulli N., Movin T., Narici M. V., Rennie M. J., The temporal responses of protein synthesis, gene expression and cell signalling in human quadriceps muscle and patellar tendon to disuse The Journal of Physiology 2007 585 1 241 251 (Pubitemid 350131116)
75. Kachaeva E. V., Turtikova O. V., Lensoo T. A., Shenkman B. S., Insulin-like growth factor 1 and the key markers of proteolysis during the acute period of readaptation of the muscle atrophied as a result of unloading Biofizika 2010 55 6 1108 1116
76. Vermaelen M., Marini J.-F., Chopard A., Benyamin Y., Mercier J., Astier C., Ubiquitin targeting of rat muscle proteins during short periods of unloading Acta Physiologica Scandinavica 2005 185 1 33 40 (Pubitemid 41243249)
77. Tskhovrebova L., Trinick J., Muscle disease: a giant feels the strain Nature Medicine 2005 11 5 478 479 (Pubitemid 40685968)
78. Schiaffino S., HanzlkovVra, Studies on the effect of denervation in developing muscle. II. The lysosomal system Journal of Ultrasructure Research 1972 39 1-2 1 14
79. Witt S. H., Granzier H., Witt C. C., Labeit S., MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination Journal of Molecular Biology 2005 350 4 713 722 (Pubitemid 40848669)
80. Moriscot A. S., Baptista I. L., Bogomolovas J., Witt C., Hirner S., Granzier H., Labeit S., MuRF1 is a muscle fiber-type II associated factor and together with MuRF2 regulates type-II fiber trophicity and maintenance Journal of Structural Biology 2010 170 2 344 353
81. Labeit S., Kohl C. H., Witt C. C., Labeit D., Jung J., Granzier H., Modulation of muscle atrophy, fatigue and MLC phosphorylation by MuRF1 as indicated by hindlimb suspension studies on MuRF1-KO mice Journal of Biomedicine and Biotechnology 2010 2010 9
82. Bozzo C., Stevens L., Toniolo L., Mounier Y., Reggiani C., Increased phosphorylation of myosin light chain associated with slow-to-fast transition in rat soleus American Journal of Physiology 2003 285 3 C575 C583
83. Potthoff M. J., Wu H., Arnold M. A., Shelton J. M., Backs J., McAnally J., Richardson J. A., Bassel-Duby R., Olson E. N., Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers The Journal of Clinical Investigation 2007 117 9 2459 2467 (Pubitemid 47494347)
84. Spte U., Schulze P. C., Proinflammatory cytokines and skeletal muscle Current Opinion in Clinical Nutrition and Metabolic Care 2004 7 3 265 269 (Pubitemid 40340663)
85. McKinnell I. W., Rudnicki M. A., Molecular mechanisms of muscle atrophy Cell 2004 119 7 907 910 (Pubitemid 40037604)
86. Cai D., Frantz J. D., Tawa N. E., Melendez P. A., Oh B. C., Lidov H. G. W., Hasselgren P. O., Frontera W. R., Lee J., Glass D. J., Shoelson S. E., IKK /NF- B activation causes severe muscle wasting in mice Cell 2004 119 2 285 298 (Pubitemid 39360909)
87. Bridge Hunter R., Stevenson E. J., Alan Koncarevi C., Mitchell-Felton H., Essig D. A., Kandarian S. C., Activation of an alternative NF- B pathway in skeletal muscle during disuse atrophy The FASEB Journal 2002 16 6 529 538 (Pubitemid 34273236)
88. Judge A. R., Koncarevic A., Hunter R. B., Liou H. C., Jackman R. W., Kandarian S. C., Role for I B, but not c-Rel, in skeletal muscle atrophy American Journal of Physiology 2007 292 1 C372 C382
89. Senf S. M., Dodd S. L., McClung J. M., Judge A. R., Hsp70 overexpression inhibits NF- B and Foxo3a transcriptional activities and prevents skeletal muscle atrophy The FASEB Journal 2008 22 11 3836 3845
90. Stitt T. N., Drujan D., Clarke B. A., Panaro F., Timofeyva Y., Kline W. O., Gonzalez M., Yancopoulos G. D., Glass D. J., The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors Molecular Cell 2004 14 3 395 403 (Pubitemid 38591410)
91. Kaestner K. H., Knchel W., Martnez D. E., Unified nomenclature for the winged helix/forkhead transcription factors Genes and Development 2000 14 2 142 146 (Pubitemid 30070978)
92. Huang H., Tindall D. J., Regulation of FOXO protein stability via ubiquitination and proteasome degradation Biochimica et Biophysica Acta 2011 1813 11 1961 1964
93. Sandri M., Sandri C., Gilbert A., Skurk C., Calabria E., Picard A., Walsh K., Schiaffino S., Lecker S. H., Goldberg A. L., Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy Cell 2004 117 3 399 412 (Pubitemid 38534545)
94. Kamei Y., Miura S., Suzuki M., Kai Y., Mizukami J., Taniguchi T., Mochida K., Hata T., Matsuda J., Aburatani H., Nishino I., Ezaki O., Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated type I (slow twitch/red muscle) fiber genes, and impaired glycemic control The Journal of Biological Chemistry 2004 279 39 41114 41123 (Pubitemid 39287713)
95. De Alvaro C., Teruel T., Hernandez R., Lorenzo M., Tumor necrosis factor alpha produces insulin resistance in skeletal muscle by activation of inhibitor kappaB kinase in a p38 MAPK-dependent manner The Journal of Biological Chemistry 2004 279 17 17070 17078 (Pubitemid 38560462)
96. Dogra C., Changotra H., Wedhas N., Qin X., Wergedal J. E., Kumar A., TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine The FASEB Journal 2007 21 8 1857 1869 (Pubitemid 46855631)
97. Hirosumi J., Tuncman G., Chang L., Grgn C. Z., Uysal K. T., Maeda K., Karin M., Hotamisligil G. S., A central, role for JNK in obesity and insulin resistance Nature 2002 420 6913 333 336 (Pubitemid 35398190)
98. Mourkioti F., Kratsios P., Luedde T., Song Y. H., Delafontaine P., Adami R., Parente V., Bottinelli R., Pasparakis M., Rosenthal N., Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration The Journal of Clinical Investigation 2006 116 11 2945 2954 (Pubitemid 44684479)
99. Han B., Zhu M. J., Ma C., Du M., Rat hindlimb unloading down-regulates insulin like growth factor-1 signaling and AMP-activated protein kinase, and leads to severe atrophy of the soleus muscle Applied Physiology, Nutrition and Metabolism 2007 32 6 1115 1123
100. Nakao R., Hirasaka K., Goto J., Ishidoh K., Yamada C., Ohno A., Okumura Y., Nonaka I., Yasutomo K., Baldwin K. M., Kominami E., Higashibata A., Nagano K., Tanaka K., Yasui N., Mills E. M., Takeda S., Nikawa T., Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading Molecular and Cellular Biology 2009 29 17 4798 4811
101. McFarlane C., Hennebry A., Thomas M., Plummer E., Ling N., Sharma M., Kambadur R., Myostatin signals through Pax7 to regulate satellite cell self-renewal Experimental Cell Research 2008 314 2 317 329 (Pubitemid 350225602)
102. Allen D. L., Unterman T. G., Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors American Journal of Physiology 2007 292 1 C188 C199
103. McCroskery S., Thomas M., Maxwell L., Sharma M., Kambadur R., Myostatin negatively regulates satellite cell activation and self-renewal Journal of Cell Biology 2003 162 6 1135 1147 (Pubitemid 37174195)
104. Massagué J., Seoane J., Wotton D., Smad transcription factors Genes and Development 2005 19 23 2783 2810 (Pubitemid 41739965)
105. Gomis R. R., Alarcn C., He W., Wang Q., Seoane J., Lash A., Massagué J., A FoxO-Smad synexpression group in human keratinocytes Proceedings of the National Academy of Sciences of the United States of America 2006 103 34 12747 12752 (Pubitemid 44298632)
106. Shintani T., Klionsky D. J., Autophagy in health and disease: a double-edged sword Science 2004 306 5698 990 995 (Pubitemid 39482894)
107. O'Leary M. F. N., Hood D. A., Denervation-induced oxidative stress and autophagy signaling in muscle Autophagy 2009 5 2 230 231
108. Tischler M. E., Rosenberg S., Satarug S., Henriksen E. J., Kirby C. R., Tome M., Chase P., Different mechanisms of increased proteolysis in atrophy induced by denervation or unweighting of rat soleus muscle Metabolism 1990 39 7 756 763 (Pubitemid 20198271)
109. Furuno K., Goodman M. N., Goldberg A. L., Role of different proteolytic systems in the degradation of muscle proteins during denervation atrophy The Journal of Biological Chemistry 1990 265 15 8550 8557
110. Deval C., Mordier S., Obled C., Bechet D., Combaret L., Attaix D., Ferrara M., Identification of cathepsin L as a differentially expressed message associated with skeletal muscle wasting Biochemical Journal 2001 360 1 143 150 (Pubitemid 33081958)
111. Sandri M., Signaling in muscle atrophy and hypertrophy Physiology 2008 23 3 160 170
112. Goll D. E., Neti G., Mares S. W., Thompson V. F., Myofibrillar protein turnover: the proteasome and the calpains Journal of Animal Science 2008 86 14 E19 E35
113. Tassa A., Roux M. P., Attaix D., Bechet D. M., Class III phosphoinositide 3-kinase-Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C 2 C 2 myotubes Biochemical Journal 2003 376 3 577 586 (Pubitemid 38058057)
114. Mammucari C., Milan G., Romanello V., Masiero E., Rudolf R., Del Piccolo P., Burden S. J., Di Lisi R., Sandri C., Zhao J., Goldberg A. L., Schiaffino S., Sandri M., FoxO3 controls autophagy in skeletal muscle in vivo Cell Metabolism 2007 6 6 458 471 (Pubitemid 350163055)
115. Zhao J., Brault J. J., Schild A., Cao P., Sandri M., Schiaffino S., Lecker S. H., Goldberg A. L., FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells Cell Metabolism 2007 6 6 472 483 (Pubitemid 350163056)
116. Du J., Wang X., Miereles C., Bailey J. L., Debigare R., Zheng B., Price S. R., Mitch W. E., Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions The Journal of Clinical Investigation 2004 113 1 115 123 (Pubitemid 38541638)
117. Berthon P., Duguez S., Favier F. B., Amirouche A., Feasson L., Vico L., Denis C., Freyssenet D., Regulation of ubiquitin-proteasome system, caspase enzyme activities, and extracellular proteinases in rat soleus muscle in response to unloading Pflugers Archiv European Journal of Physiology 2007 454 4 625 633 (Pubitemid 46872895)
118. Vazeille E., Codran A., Claustre A., Averous J., Listrat A., Béchet D., Taillandier D., Dardevet D., Attaix D., Combaret L., The ubiquitin-proteasome and the mitochondria-associated apoptotic pathways are sequentially downregulated during recovery after immobilization-induced muscle atrophy American Journal of Physiology 2008 295 5 E1181 E1190
119. Siu P. M., Pistilli E. E., Alway S. E., Apoptotic responses to hindlimb suspension in gastrocnemius muscles from young adult and aged rats American Journal of Physiology 2005 289 4 R1015 R1026
120. Leeuwenburgh C., Gurley C. M., Strotman B. A., Dupont-Versteegden E. E., Age-related differences in apoptosis with disuse atrophy in soleus muscle American Journal of Physiology 2005 288 5 R1288 R1296
121. Ohanna M., Sobering A. K., Lapointe T., Lorenzo L., Praud C., Petroulakis E., Sonenberg N., Kelly P. A., Sotiropoulos A., Pende M., Atrophy of S6K1-/- skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control Nature Cell Biology 2005 7 3 286 294 (Pubitemid 40331130)
122. Henriksen E. J., Tischler M. E., Johnson D. G., Increased response to insulin of glucose metabolism in the 6-day unloaded rat soleus muscle The Journal of Biological Chemistry 1986 261 23 10707 10712 (Pubitemid 17194855)
123. Bodine S. C., Latres E., Baumhueter S., Lai V. K. M., Nunez L., Clarke B. A., Poueymirou W. T., Panaro F. J., Erqian Na, Dharmarajan K., Pan Z. Q., Valenzuela D. M., Dechiara T. M., Stitt T. N., Yancopoulos G. D., Glass D. J., Identification of ubiquitin ligases required for skeletal Muscle Atrophy Science 2001 294 5547 1704 1708 (Pubitemid 33104839)
124. Shen W. H., Boyle D. W., Wisniowski P., Bade A., Liechty E. A., Insulin and IGF-I stimulate the formation of the eukaryotic initiation factor 4F complex and protein synthesis in C2C12 myotubes independent of availability of external amino acids Journal of Endocrinology 2005 185 2 275 289 (Pubitemid 40691794)
125. Hilder T. L., Tou J. C. L., Grindeland R. E., Wade C. E., Graves L. M., Phosphorylation of insulin receptor substrate-1 serine 307 correlates with JNK activity in atrophic skeletal muscle FEBS Letters 2003 553 1-2 63 67 (Pubitemid 37206325)
126. Machida S., Booth F. W., Changes in signalling molecule levels in 10-day hindlimb immobilized rat muscles Acta Physiologica Scandinavica 2005 183 2 171 179 (Pubitemid 40203610)
127. Csukly K., Marqueste T., Gardiner P., Sensitivity of rat soleus muscle to a mechanical stimulus is decreased following hindlimb unweighting European Journal of Applied Physiology 2005 95 2-3 243 249 (Pubitemid 41829791)
128. Paul P. K., Gupta S. K., Bhatnagar S., Panguluri S. K., Darnay B. G., Choi Y., Kumar A., Targeted ablation of TRAF6 inhibits skeletal muscle wasting in mice Journal of Cell Biology 2010 191 7 1395 1411
129. Csibi A., Tintignac L. A., Leibovitch M. P., Leibovitch S. A., eIF3-f function in skeletal muscles: to stand at the crossroads of atrophy and hypertrophy Cell Cycle 2008 7 12 1698 1701 (Pubitemid 351988733)
130. Zhou C., Arslan F., Wee S., Krishnan S., Ivanov A. R., Oliva A., Leatherwood J., Wolf D. A., PCI proteins eIF3e and eIF3m define distinct translation initiation factor 3 complexes BMC Biology 2005 3, article 14
131. Serrano A. L., Baeza-Raja B., Perdiguero E., Jard M., Muoz-Cnoves P., Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy Cell Metabolism 2008 7 1 33 44
132. Loughna P., Goldspink G., Goldspink D. F., Effect of inactivity and passive stretch on protein turnover in phasic and postural rat muscles Journal of Applied Physiology 1986 61 1 173 179 (Pubitemid 16055674)
133. Ojima K., Kawabata Y., Nakao H., Nakao K., Doi N., Kitamura F., Ono Y., Hata S., Suzuki H., Kawahara H., Bogomolovas J., Witt C., Ottenheijm C., Labeit S., Granzier H., Toyama-Sorimachi N., Sorimachi M., Suzuki K., Maeda T., Abe K., Aiba A., Sorimachi H., Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy The Journal of Clinical Investigation 2010 120 8 2672 2683
134. Baptista I. L., Leal M. L., Artioli G. G., Aoki M. S., Fiamoncini J., Turri A. O., Curi R., Miyabara E. H., Moriscot A. S., Leucine attenuates skeletal muscle wasting via inhibition of ubiquitin ligases Muscle and Nerve 2010 41 6 800 808