BRCA2 in meiosis: Turning over a new leaf

Trends in Cell Biology

Volumn 14, Issue 8, 2004, Pages 401-404

  Gudmundsdottir, Katrin ^a   Ashworth, Alan ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA2 PROTEIN; DOUBLE STRANDED DNA; RAD51 PROTEIN; RNA;

ARABIDOPSIS; BREAST CANCER; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CHROMOSOME; DNA REPAIR; DNA STRAND BREAKAGE; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; GENETIC SUSCEPTIBILITY; HUMAN; MAMMAL; MEIOSIS; MOLECULAR EVOLUTION; NONHUMAN; ONCOGENE; ORTHOLOGY; PLANT LEAF; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; RNA INTERFERENCE; SMUT (PLANT DISEASE);

ARABIDOPSIS; ARABIDOPSIS THALIANA; FUNGI; MAMMALIA; USTILAGO; USTILAGO MAYDIS; VERTEBRATA;

EID: 4143061460     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcb.2004.07.002     Document Type: Short Survey

References (21)

1. A. Tutt, and A. Ashworth The relationship between the roles of BRCA genes in DNA repair and cancer predisposition Trends Mol. Med. 8 2002 571 576
2. A.R. Venkitaraman Cancer susceptibility and the functions of BRCA1 and BRCA2 Cell 108 2002 171 182
3. F. Connor Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene Hum. Mol. Genet. 6 1997 291 300
4. B.J. Orelli Nine novel conserved motifs in BRCA1 identified by the chicken orthologue Oncogene 20 2001 4433 4438
5. M. Warren Structural analysis of the chicken BRCA2 gene facilitates identification of functional domains and disease causing mutations Hum. Mol. Genet. 11 2002 841 851
6. T. Lo Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer DNA Repair (Amst.) 2 2003 1015 1028
7. H. Yang BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure Science 297 2002 1837 1848
8. N. Siaud Brca2 is involved in meiosis in Arabidopsis thaliana as suggested by its interaction with Dmc1 EMBO J. 23 2004 1392 1401
9. M. Kojic BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis Mol. Cell 10 2002 683 691
10. P. Bork Internal repeats in the BRCA2 protein sequence Nat. Genet. 13 1996 22 23
11. S.C. West Molecular views of recombination proteins and their control Nat. Rev. Mol. Cell Biol. 4 2003 435 445
12. J.H. Hoeijmakers Genome maintenance mechanisms for preventing cancer Nature 411 2001 366 374
13. A. Tutt Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences EMBO J. 20 2001 4704 4716
14. J. Chen Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells Mol. Cell 2 1998 317 328
15. F. Connor Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation Nat. Genet. 17 1997 423 430
16. S.K. Sharan BRCA2 deficiency in mice leads to meiotic impairment and infertility Development 131 2004 131 142
17. F. Couteau Random chromosome segregation without meiotic arrest in both male and female meiocytes of a dmc1 mutant of Arabidopsis Plant Cell 11 1999 1623 1634
18. L.S. Symington Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair Microbiol. Mol. Biol. Rev. 66 2002 630 670
19. J.Y. Masson, and S.C. West The Rad51 and Dmc1 recombinases: a non-identical twin relationship Trends Biochem. Sci. 26 2001 131 136
20. S.K. Mahadevaiah Recombinational DNA double-strand breaks in mice precede synapsis Nat. Genet. 27 2001 271 276
21. M. Tarsounas RAD51 and DMC1 form mixed complexes associated with mouse meiotic chromosome cores and synaptonemal complexes J. Cell Biol. 147 1999 207 219