The roles of vitreal macrophages and circulating leukocytes in retinal neovascularization

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 3, 2011, Pages 1431-1438

  Kataoka, Keiko ^a   Nishiguchi, Koji M ^a   Kaneko, Hiroki ^a   van Rooijen, Nico ^b   Kachi, Shu ^a   Terasaki, Hiroko ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; CLODRONIC ACID; GREEN FLUORESCENT PROTEIN; LIPOSOME; PROTEIN IBA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; ENGRAFTMENT; HISTOPATHOLOGY; IRRADIATION; LEUKOCYTE; MACROPHAGE; MACROPHAGE MIGRATION; MICROGLIA; MOUSE; NONHUMAN; OXYGEN INDUCED RETINOPATHY; PERINATAL PERIOD; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RETINA; RETINA NEOVASCULARIZATION; RETINOPATHY; VITREAL MACROPHAGE; VITREOUS BODY; WILD TYPE;

ANIMALS; BONE MARROW TRANSPLANTATION; CALCIUM-BINDING PROTEINS; CELL MOVEMENT; CLODRONIC ACID; DISEASE MODELS, ANIMAL; GREEN FLUORESCENT PROTEINS; INTRAVITREAL INJECTIONS; LEUKOCYTES; LYMPHOCYTE DEPLETION; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROFILAMENT PROTEINS; MICROGLIA; OXYGEN; PHAGOCYTOSIS; RETINAL NEOVASCULARIZATION; RETINAL VESSELS; VITREOUS BODY;

EID: 79955937034     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-5798     Document Type: Article

References (28)

1. Risau W. Mechanisms of angiogenesis. Nature. 1997;386:671-674.
2. Risau W, Flamme I. Vasculogenesis. Annu Rev Cell Dev Biol. 1995;11:73-91.
3. Rafii S, Lyden D. Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration. Nat Med. 2003; 9:702-712.
4. Purhonen S, Palm J, Rossi D, et al. Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth. Proc Natl Acad Sci USA. 2008;105:6620-6625.
5. Grant MB, May WS, Caballero S, et al. Adult hematopoietic stem cells provide functional hemangioblast activity during retinal neovascularization. Nat Med. 2002;8:607-612.
6. Fruttiger M. Development of the mouse retinal vasculature: angiogenesis versus vasculogenesis. Invest Ophthalmol Vis Sci. 2002; 43:522-527.
7. Curatola AM, Moscatelli D, Norris A, Hendricks-Munoz K. Retinal blood vessels develop in response to local VEGF-A signals in the absence of blood flow. Exp Eye Res. 2005;81:147-158.
8. Fruttiger M. Development of the retinal vasculature. Angiogenesis. 2007;10:77-88.
9. Ito M, Yoshioka M. Regression of the hyaloid vessels and papillary membrane of the mouse. Anat Embryol (Berl). 1999;200:403-411.
10. Blanks JC, Johnson LV. Vascular atrophy in the retinal degenerative rd mouse. J Comp Neurol. 1986;254:543-553.
11. Ishida S, Yamashiro K, Usui T, et al. Leukocytes mediate retinal vascular remodeling during development and vaso-obliteration in disease. Nat Med. 2003;9:781-788.
12. Ishida S, Usui T, Yamashiro K, et al. VEGF164-mediated inflammation is required for pathological, but not physiological, ischemiainduced retinal neovascularization. J Exp Med. 2003;198:483-489.
13. Zou H, Otani A, Oishi A, et al. Bone marrow-derived cells differentially involved in pathological and physiological retinal angiogenesis in mice. Biochem Biophys Res Commun. 2010;391:1268-1273.
14. Matsubara T, Pararajasegaram G, Wu GS, Rao NA. Retinal microglia differentially express phenotypic markers of antigen-presenting cells in vitro. Invest Ophthalmol Vis Sci. 1999;40:3186-3193.
15. Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, Terasaki H. Characteristics of bone marrow-derived microglia in the normal and injured retina. Invest Ophthalmol Vis Sci. 2008;49:4162-4168.
16. Hisatomi T, Sakamoto T, Sonoda KH, et al. Clearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3. Am J Pathol. 2003;162: 1869-1879.
17. Kubota Y, Takubo K, Shimizu T, et al. M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med. 2009;206:1089-1102.
18. Ritter MR, Banin E, Moreno SK, Aguilar E, Dorrell MI, Friedlander M. Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy. J Clin Invest. 2006;116:3266-3276.
19. Nakazawa T, Hisatomi T, Nakazawa C, et al. Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis. Proc Natl Acad Sci USA. 2007;104:2425-2430.
20. Sasahara M, Otani A, Oishi A, et al. Activation of bone marrowderived microglia promotes photoreceptor survival in inherited retinal degeneration. Am J Pathol. 2008;172:1693-1703.
21. Harada T, Harada C, Kohsaka S, et al. Microglia-Muller glia cell interactions control neurotrophic factor production during lightinduced retinal degeneration. J Neurosci. 2002;22:9228-9236.
22. Okabe M, Ikawa M, Kominami K, Nakanishi T, Nishimune Y. 'Green mice' as a source of ubiquitous green cells. FEBS Lett. 1997;407:313-319.
23. Kaneko H, Nishiguchi KM, Nakamura M, Kachi S, Terasaki H. Retardation of photoreceptor degeneration in the detached retina of rd1 mouse. Invest Ophthalmol Vis Sci. 2008;49:781-787.
24. Nishiguchi KM, Nakamura M, Kaneko H, Kachi S, Terasaki H. The role of VEGF and VEGFR2/Flk1 in proliferation of retinal progenitor cells in murine retinal degeneration. Invest Ophthalmol Vis Sci. 2007;48:4315-4320.
25. Sands MS, Barker JE. Percutaneous intravenous injection in neonatal mice. Lab Anim Sci. 1999;49:328-330.
26. van Rooijen N, Sanders A. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods. 1994;174:83-93.
27. Bischoff PM, Wajer SD, Flower RW. Scanning electron microscopic studies of the hyaloid vascular system in newborn mice exposed to O2 and CO2. Graefes Arch Clin Exp Ophthalmol. 1983;220:257-263.
28. van Rooijen N, Sanders A, van den Berg TK. Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine. J Immunol Methods. 1996; 193:93-99.