Multimodality measurements of small airways disease

European Respiratory Journal

Volumn 27, Issue 2, 2006, Pages 250-252

  King, G G ^a,b,c   Salome, C M ^b,c  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c The Cooperative Research Centre for Asthma and Airways   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; METHACHOLINE; MONTELUKAST; PLACEBO; XENON;

AIRWAY OBSTRUCTION; ASTHMA; BREATH ANALYSIS; CLINICAL FEATURE; CLINICAL TRIAL; CONTRAST ENHANCEMENT; CORRELATION ANALYSIS; DISEASE EXACERBATION; DRUG MECHANISM; EDITORIAL; FORCED EXPIRATORY VOLUME; FUNCTIONAL ASSESSMENT; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; IMAGE ANALYSIS; LUNG CLOSING VOLUME; LUNG COMPLIANCE; LUNG FUNCTION TEST; LUNG PARENCHYMA; LUNG VOLUME; MATHEMATICAL MODEL; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUALITY OF LIFE; RISK ASSESSMENT; SMALL AIRWAY DISEASE; SMOKING; SPIROMETRY;

ACETATES; ANTI-ASTHMATIC AGENTS; ASTHMA; HUMANS; QUINOLINES; RESPIRATORY FUNCTION TESTS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 31844446296     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.06.00144705     Document Type: Editorial

References (19)

1. Hogg JC, Macklem PT, Thurlbeck WM. Site and nature of airway obstruction in chronic obstructive lung disease. N Engl J Med 1968; 278: 1355-1360.
2. Cosio M, Ghezzo H, Hogg JC, et al. The relations between structural changes in small airways and pulmonary-function tests. N Engl J Med 1978; 298: 1277-1281.
3. Verbanck S, Schuermans D, Meysman M, Paiva M, Vincken W. Noninvasive assessment of airway alterations in smokers: the small airways revisited. Am J Respir Crit Care Med 2004; 170: 414-419.
4. Carroll N, Elliot J, Morton A, James A. The structure of large and small airways in nonfatal and fatal asthma. Am Rev Respir Dis 1993; 147: 405-410.
5. Kuwano K, Bosken C, Pare P, Bai T, Wiggs B, Hogg J. Small airways dimensions in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 1993; 148: 1220-1225.
6. Zeidler MR, Kleerup EC, Goldin JG, et al. Montelukast improves regional air-trapping due to small airways obstruction in asthma. Eur Respir J 2006; 27: 307-315.
7. in't Veen JC, Beekman AJ, Bel EH, Sterk PJ. Recurrent exacerbations in severe asthma are associated with enhanced airway closure during stable episodes. Am J Respir Crit Care Med 2000; 161: 1902-1906.
8. King GG, Eberl S, Salome CM, Young IH, Woolcock AJ. Differences in airway closure between normals and asthmatics measured by SPECT and Technegas. Am J Resp Crit Care Med 1998; 158: 1900-1908.
9. King GG, Downie SR, Verbanck S, et al. Effects of methacholine on small airway function measured by forced oscillation technique and multiple breath nitrogen washout in normal subjects. Respir Physiol Neurobiol 2005; 148: 165-177.
10. Woolcock AJ, Vincent NJ, Macklem PT. Frequency dependence of compliance as a test for obstruction in the small airways. J Clin Invest 1969; 48: 1097-1106.
11. Despas PJ, Leroux M, Macklem PT. Site of airway obstruction as determined by measuring maximal expiratory flow breathing air and a helium-oxygen mixture. J Clin Invest 1972; 51: 3235-3243.
12. Kaminsky DA, Bates JH, Irvin CG. Effects of cool, dry air stimulation on peripheral lung mechanics in asthma. Am J Respir Crit Care Med 2000; 162: 179-186.
13. Venegas JG, Winkler T, Musch G, et al. Self-organized patchiness in asthma as a prelude to catastrophic shifts. Nature 2005; 434: 777-782.
14. Samee S, Altes T, Powers P, et al. Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: assessment of response to methacholine and exercise challenge. J Allergy Clin Immunol 2003; 111: 1205-1211.
15. Macklem PT. The physiology of small airways. Am J Respir Crit Care Med 1998; 157: 181S-183S.
16. Kreck TC, Krueger MA, Altemeier WA, et al. Determination of regional ventilation and perfusion in the lung using xenon and computed tomography. J Appl Physiol 2001; 91: 1741-1749.
17. King GG, Carroll JD, Muller NL, et al. Heterogeneity of narrowing in normal and asthmatic airways measured by HRCT. Eur Respir J 2004; 24: 211-218.
18. Nakano Y, Wong JC, de Jong PA, et al. The prediction of small airway dimensions using computed tomography. Am J Respir Crit Care Med 2005; 171: 142-146.
19. Tgavalekos NT, Tawhai M, Harris RS, et al. Identifying airways responsible for heterogeneous ventilation and mechanical dysfunction in asthma: an image functional modeling approach. J Appl Physiol 2005; 99: 2388-2397.