Evidence of acinar airway involvement in asthma

American Journal of Respiratory and Critical Care Medicine

Volumn 159, Issue 5 I, 1999, Pages 1545-1550

  Verbanck, Sylvia ^a   Schuermans, Daniël ^b   Noppen, Marc ^b   Van Muylem, Alain ^b   Paiva, Manuel ^b   Vincken, Walter ^b  

^a UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

SALBUTAMOL;

ADULT; AGED; AIRWAY CONDUCTANCE; ARTICLE; ASTHMA; BREATH ANALYSIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; DRUG EFFECT; HUMAN; INHALATIONAL DRUG ADMINISTRATION; LUNG VENTILATION DISTRIBUTION; NITROGEN WASHOUT; PRIORITY JOURNAL; RESPIRATORY AIRFLOW;

EID: 0032936263     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.159.5.9809017     Document Type: Article

References (23)

1. 1998. Small airways and asthma. Am. J. Respir. Crit. Care Med. 157(Suppl.): S173-S207.
2. Verbanck, S., D. Schuermans, A. Van Muylem, M. Noppen, M. Paiva, and W. Vincken. 1997. Ventilation distribution during histamine provocation. J. Appl. Physiol. 83:1907-1916.
3. Crawford, A. B. H., M. Makowska, M. Paiva, and L. E. Engel. 1985. Convection- and diffusion-dependent ventilation maldistribution in normal subjects. J. Appl. Physiol. 59:838-846.
4. Tsang, J. Y., M. J. Emery, and M. P. Hlastala. 1997. Ventilation inhomogeneity in oleic acid-induced pulmonary edema. J. Appl. Physiol. 82: 1040-1045.
5. Verbanck, S., D. Schuermans, A. Van Muylem, C. Melot, M. Noppen, W. Vincken, and M. Paiva. 1998. Conductive and acinar lung zone contribution to ventilation inhomogeneity in COPD. Am. J. Respir. Crit. Care Med. 157:1573-1577.
6. Paiva, M., and L. A. Engel. 1989. Gas mixing in the lung periphery. In H. K. Chang and M. Paiva, editors. Respiratory Physiology: An Analytical Approach. Marcel Dekker, New York. 245-276.
7. Verbanck, S., and M. Paiva. 1990. Model simulations of gas mixing and ventilation distribution in the human lung. J. Appl. Physiol. 69:2269-2279.
8. Melchor, R., M. F. Biddiscombe, V. H. F. Mak, M. D. Short, and S. G. Spiro. 1993. Lung deposition patterns of directly labelled salbutamol in normal subjects and in patients with reversible airflow obstruction. Thorax 48:506-511.
9. Lipworth, B. J., D. M. Newnham, R. A. Clark, D. P. Dhillon, J. H. Winter, and D. G. McDevitt. 1995. Comparison of the relative airways and systemic potencies of inhaled fenoterol and salbutamol in asthmatic patients. Thorax 50:54-61.
10. American Thoracic Society. 1987. ATS statement: standardization of spirometry. 1987 update. Am. Rev. Respir. Dis. 136:1285-1298.
11. National Institutes of Health (NHLBI). January 1995. Global initiative for asthma. Global strategy for asthma management and prevention. NHLBI/WHO workshop report, March 1993. NIH/NHLBI Publication No. 95-3659.
12. American Thoracic Society. 1995. ATS statement: standards for the diagnosis and care of patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 152(Part 2):S77-S120.
13. Quanjer, H., G. J. Tammeling, J. E. Cotes, O. F. Pedersen, R. Peslin, and J.-C. Yernault. 1993. Lung volumes and forced expiratory flows. Eur. Respir. J. 6(Suppl. 16):5-40.
14. Holgate, S. T. 1996. The inflammation-repair cycle in asthma: possible new biomarkers of disease activity. Eur. Respir. Rev. 6:4-10.
15. Wagner, E. M., M. C. Liu, G. G. Weinmann, S. Permutt, and E. R. Bleecker. 1990. Peripheral lung resistance in normal and asthmatic subjects. Am. Rev. Respir. Dis. 141:584-588.
16. Yanai, M., T. Ohrui, K. Sekizawa, Y. Shimizu, H. Sasaki, and T. Takishima. 1991. Effective site of bronchodilation by antiasthma drugs in subjects with asthma. J. Allergy Clin. Immunol. 87:1080-1087.
17. Fairshter, R. D., and A. F. Wilson. 1980. Relationship between the site of airflow limitation and localization of the bronchodilator response in asthma. Am. Rev. Respir. Dis. 122:27-32.
18. 2 test. Bull. Eur. Physiopathol. Respir. 22:489-494.
19. Olofsson, J., B. Bake, N. Blomqvist, and B. E. Skoogh. 1985. Effect of increasing bronchodilatation on the single breath nitrogen test. Bull. Eur. Physiopathol. Respir. 21:31-36.
20. Cooper, D. M., R. B. Mellins, and A. L. Mansell. 1983. Ventilation distribution and density dependence of expiratory flow in asthmatic children. J. Appl. Physiol. 54:1125-1130.
21. Peces-Barba Romero, G. J. J. Cabanillas, M. L. Rubio, J. Vallejo, and N. Gonzalez Mangado. 1991. Ventilation distribution in asthmatic patients. Eur. Respir. J. 4(Suppl. 14):P1377.
22. 2 washout in healthy, asthmatic and cystic fibrosis subjects. J. Appl. Physiol. 68:2139-2149.
23. Paiva, M., A. van Muylem, P. Ravez, and J. C. Yernault. 1986. Preinspiratory lung volume dependence of the slope of the alveolar plateau. Respir. Physiol. 63:327-338.