-
1
-
-
0023898917
-
The role of hemolysin for intracellular growth of Listeria monocytogenes
-
D. Portnoy, P.S. Jacks, and D. Hinrichs The role of hemolysin for intracellular growth of Listeria monocytogenes J. Exp. Med. 167 1988 1459 1471
-
(1988)
J. Exp. Med.
, vol.167
, pp. 1459-1471
-
-
Portnoy, D.1
Jacks, P.S.2
Hinrichs, D.3
-
2
-
-
0028945951
-
Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene
-
M.M. Awad, A.E. Bryant, D.L. Stevens, and J.I. Rood Virulence studies on chromosomal alpha-toxin and theta-toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of alpha-toxin in Clostridium perfringens-mediated gas gangrene Mol. Microbiol. 15 1995 191 202
-
(1995)
Mol. Microbiol.
, vol.15
, pp. 191-202
-
-
Awad, M.M.1
Bryant, A.E.2
Stevens, D.L.3
Rood, J.I.4
-
3
-
-
0032785378
-
Use of genetically manipulated strains of Clostridium perfringens reveals that both alpha-toxin and theta-toxin are required for vascular leukostasis to occur in experimental gas gangrene
-
D.M. Ellemor, R.N. Baird, M.M. Awad, R.L. Boyd, J.I. Rood, and J.J. Emmins Use of genetically manipulated strains of Clostridium perfringens reveals that both alpha-toxin and theta-toxin are required for vascular leukostasis to occur in experimental gas gangrene Infect. Immun. 67 1999 4902 4907
-
(1999)
Infect. Immun.
, vol.67
, pp. 4902-4907
-
-
Ellemor, D.M.1
Baird, R.N.2
Awad, M.M.3
Boyd, R.L.4
Rood, J.I.5
Emmins, J.J.6
-
4
-
-
0035846909
-
Cytolysin-mediated translocation (CMT): A functional equivalent of type III secretion in gram-positive bacteria
-
J.C. Madden, N. Ruiz, and M. Caparon Cytolysin-mediated translocation (CMT): a functional equivalent of type III secretion in gram-positive bacteria Cell 104 2001 143 152
-
(2001)
Cell
, vol.104
, pp. 143-152
-
-
Madden, J.C.1
Ruiz, N.2
Caparon, M.3
-
5
-
-
8744310905
-
Lipid rafts clustering and signalling by listeriolysin O
-
N.O. Gekara, and S. Weiss Lipid rafts clustering and signalling by listeriolysin O Biochem. Soc. Trans. 32 2004 712 714
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 712-714
-
-
Gekara, N.O.1
Weiss, S.2
-
6
-
-
34447619164
-
+ signalling by listeriolysin O, the cholesterol-dependent cytolysin of Listeria monocytogenes
-
+ signalling by listeriolysin O, the cholesterol-dependent cytolysin of Listeria monocytogenes Cell. Microbiol. 9 2007 2008 2021
-
(2007)
Cell. Microbiol.
, vol.9
, pp. 2008-2021
-
-
Gekara, N.O.1
Westphal, K.2
Ma, B.3
Rohde, M.4
Groebe, L.5
Weiss, S.6
-
7
-
-
34548080058
-
Histone modifications induced by a family of bacterial toxins
-
M.A. Hamon, E. Batsche, B. Regnault, T.N. Tham, S. Seveau, C. Muchardt, and P. Cossart Histone modifications induced by a family of bacterial toxins Proc. Natl. Acad. Sci. U. S. A. 104 2007 13467 13472
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 13467-13472
-
-
Hamon, M.A.1
Batsche, E.2
Regnault, B.3
Tham, T.N.4
Seveau, S.5
Muchardt, C.6
Cossart, P.7
-
8
-
-
0035144549
-
Human endothelial cell activation and mediator release in response to Listeria monocytogenes virulence factors
-
F. Rose, S.A. Zeller, T. Chakraborty, E. Domann, T. Machleidt, M. Kronke, W. Seeger, F. Grimminger, and U. Sibelius Human endothelial cell activation and mediator release in response to Listeria monocytogenes virulence factors Infect. Immun. 69 2001 897 905
-
(2001)
Infect. Immun.
, vol.69
, pp. 897-905
-
-
Rose, F.1
Zeller, S.A.2
Chakraborty, T.3
Domann, E.4
MacHleidt, T.5
Kronke, M.6
Seeger, W.7
Grimminger, F.8
Sibelius, U.9
-
9
-
-
0036073612
-
Mobilization of protein kinase C in macrophages induced by Listeria monocytogenes affects its internalization and escape from the phagosome
-
S.J. Wadsworth, and H. Goldfine Mobilization of protein kinase C in macrophages induced by Listeria monocytogenes affects its internalization and escape from the phagosome Infect. Immun. 70 2002 4650 4660
-
(2002)
Infect. Immun.
, vol.70
, pp. 4650-4660
-
-
Wadsworth, S.J.1
Goldfine, H.2
-
10
-
-
0018821155
-
Activation of human neutrophil metabolism by streptolysin O
-
B.R. Andersen, and J.L. Duncan Activation of human neutrophil metabolism by streptolysin O J. Infect. Dis. 141 1980 680 685
-
(1980)
J. Infect. Dis.
, vol.141
, pp. 680-685
-
-
Andersen, B.R.1
Duncan, J.L.2
-
11
-
-
0035059186
-
Pneumolysin potentiates production of prostaglandin E(2) and leukotriene B(4) by human neutrophils
-
R. Cockeran, H.C. Steel, T.J. Mitchell, C. Feldman, and R. Anderson Pneumolysin potentiates production of prostaglandin E(2) and leukotriene B(4) by human neutrophils Infect. Immun. 69 2001 3494 3496
-
(2001)
Infect. Immun.
, vol.69
, pp. 3494-3496
-
-
Cockeran, R.1
Steel, H.C.2
Mitchell, T.J.3
Feldman, C.4
Anderson, R.5
-
12
-
-
0035865826
-
Proinflammatory interactions of pneumolysin with human neutrophils
-
R. Cockeran, A.J. Theron, H.C. Steel, N.M. Matlola, T.J. Mitchell, C. Feldman, and R. Anderson Proinflammatory interactions of pneumolysin with human neutrophils J. Infect. Dis. 183 2001 604 611
-
(2001)
J. Infect. Dis.
, vol.183
, pp. 604-611
-
-
Cockeran, R.1
Theron, A.J.2
Steel, H.C.3
Matlola, N.M.4
Mitchell, T.J.5
Feldman, C.6
Anderson, R.7
-
13
-
-
0036139243
-
Induction of gamma interferon and nitric oxide by truncated pneumolysin that lacks pore-forming activity
-
H. Baba, I. Kawamura, C. Kohda, T. Nomura, Y. Ito, T. Kimoto, I. Watanabe, S. Ichiyama, and M. Mitsuyama Induction of gamma interferon and nitric oxide by truncated pneumolysin that lacks pore-forming activity Infect. Immun. 70 2002 107 113
-
(2002)
Infect. Immun.
, vol.70
, pp. 107-113
-
-
Baba, H.1
Kawamura, I.2
Kohda, C.3
Nomura, T.4
Ito, Y.5
Kimoto, T.6
Watanabe, I.7
Ichiyama, S.8
Mitsuyama, M.9
-
14
-
-
0037103529
-
Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro
-
R. Cockeran, C. Durandt, C. Feldman, T.J. Mitchell, and R. Anderson Pneumolysin activates the synthesis and release of interleukin-8 by human neutrophils in vitro J. Infect. Dis. 186 2002 562 565
-
(2002)
J. Infect. Dis.
, vol.186
, pp. 562-565
-
-
Cockeran, R.1
Durandt, C.2
Feldman, C.3
Mitchell, T.J.4
Anderson, R.5
-
15
-
-
17644428099
-
Pneumolysin-mediated activation of NFkappaB in human neutrophils is antagonized by docosahexaenoic acid
-
H. Fickl, R. Cockeran, H.C. Steel, C. Feldman, G. Cowan, T.J. Mitchell, and R. Anderson Pneumolysin-mediated activation of NFkappaB in human neutrophils is antagonized by docosahexaenoic acid Clin. Exp. Immunol. 140 2005 274 281
-
(2005)
Clin. Exp. Immunol.
, vol.140
, pp. 274-281
-
-
Fickl, H.1
Cockeran, R.2
Steel, H.C.3
Feldman, C.4
Cowan, G.5
Mitchell, T.J.6
Anderson, R.7
-
16
-
-
56749156007
-
Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases
-
J. Bernatoniene, Q. Zhang, S. Dogan, T.J. Mitchell, J.C. Paton, and A. Finn Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases J. Infect. Dis. 198 2008 1823 1833
-
(2008)
J. Infect. Dis.
, vol.198
, pp. 1823-1833
-
-
Bernatoniene, J.1
Zhang, Q.2
Dogan, S.3
Mitchell, T.J.4
Paton, J.C.5
Finn, A.6
-
17
-
-
0027717232
-
Clostridium perfringens invasiveness is enhanced by effects of theta toxin upon PMNL structure and function: The roles of leukocytotoxicity and expression of CD11/CD18 adherence glycoprotein
-
A.E. Bryant, R. Bergstrom, G.A. Zimmerman, J.L. Salyer, H.R. Hill, R.K. Tweten, H. Sato, and D.L. Stevens Clostridium perfringens invasiveness is enhanced by effects of theta toxin upon PMNL structure and function: the roles of leukocytotoxicity and expression of CD11/CD18 adherence glycoprotein FEMS Immunol. Med. Microbiol. 7 1993 321 336
-
(1993)
FEMS Immunol. Med. Microbiol.
, vol.7
, pp. 321-336
-
-
Bryant, A.E.1
Bergstrom, R.2
Zimmerman, G.A.3
Salyer, J.L.4
Hill, H.R.5
Tweten, R.K.6
Sato, H.7
Stevens, D.L.8
-
18
-
-
0027173212
-
Role of theta-toxin, a sulfhydryl-activated cytolysin, in the pathogenesis of clostridial gas gangrene
-
D.L. Stevens, and A.E. Bryant Role of theta-toxin, a sulfhydryl-activated cytolysin, in the pathogenesis of clostridial gas gangrene Clin. Infect. Dis. 16 1993 S195 S199
-
(1993)
Clin. Infect. Dis.
, vol.16
-
-
Stevens, D.L.1
Bryant, A.E.2
-
19
-
-
0023228890
-
Effects of alpha and theta toxins from Clostridium perfringens on human polymorphonuclear leukocytes
-
D.L. Stevens, J. Mitten, and C. Henry Effects of alpha and theta toxins from Clostridium perfringens on human polymorphonuclear leukocytes J. Infect. Dis. 156 1987 324 333
-
(1987)
J. Infect. Dis.
, vol.156
, pp. 324-333
-
-
Stevens, D.L.1
Mitten, J.2
Henry, C.3
-
20
-
-
0023930231
-
Lethal effects and cardiovascular effects of purified alpha- and theta-toxins from Clostridium perfringens
-
D.L. Stevens, B.E. Troyer, D.T. Merrick, J.E. Mitten, and R.D. Olson Lethal effects and cardiovascular effects of purified alpha- and theta-toxins from Clostridium perfringens J. Infect. Dis. 157 1988 272 279
-
(1988)
J. Infect. Dis.
, vol.157
, pp. 272-279
-
-
Stevens, D.L.1
Troyer, B.E.2
Merrick, D.T.3
Mitten, J.E.4
Olson, R.D.5
-
21
-
-
30744464885
-
Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin
-
L.A. Kirkham, J.M. Jefferies, A.R. Kerr, Y. Jing, S.C. Clarke, A. Smith, and T.J. Mitchell Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin J. Clin. Microbiol. 44 2006 151 159
-
(2006)
J. Clin. Microbiol.
, vol.44
, pp. 151-159
-
-
Kirkham, L.A.1
Jefferies, J.M.2
Kerr, A.R.3
Jing, Y.4
Clarke, S.C.5
Smith, A.6
Mitchell, T.J.7
-
22
-
-
34548497122
-
Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaks
-
J.M. Jefferies, C.H. Johnston, L.A. Kirkham, G.J. Cowan, K.S. Ross, A. Smith, S.C. Clarke, A.B. Brueggemann, R.C. George, B. Pichon, G. Pluschke, V. Pfluger, and T.J. Mitchell Presence of nonhemolytic pneumolysin in serotypes of Streptococcus pneumoniae associated with disease outbreaks J. Infect. Dis. 196 2007 936 944
-
(2007)
J. Infect. Dis.
, vol.196
, pp. 936-944
-
-
Jefferies, J.M.1
Johnston, C.H.2
Kirkham, L.A.3
Cowan, G.J.4
Ross, K.S.5
Smith, A.6
Clarke, S.C.7
Brueggemann, A.B.8
George, R.C.9
Pichon, B.10
Pluschke, G.11
Pfluger, V.12
Mitchell, T.J.13
-
23
-
-
0023251174
-
Molecular cloning, characterization, and complete nucleotide sequence of the gene for pneumolysin, the sulfhydryl-activated toxin of Streptococcus pneumoniae
-
J.A. Walker, R.L. Allen, P. Falmagne, M.K. Johnson, and G.J. Boulnois Molecular cloning, characterization, and complete nucleotide sequence of the gene for pneumolysin, the sulfhydryl-activated toxin of Streptococcus pneumoniae Infect. Immun. 55 1987 1184 1189
-
(1987)
Infect. Immun.
, vol.55
, pp. 1184-1189
-
-
Walker, J.A.1
Allen, R.L.2
Falmagne, P.3
Johnson, M.K.4
Boulnois, G.J.5
-
24
-
-
0023491913
-
Nucleotide sequence of the streptolysin O (SLO) gene: Structural homologies between SLO and other membrane-damaging, thiol-activated toxins
-
M.A. Kehoe, L. Miller, J.A. Walker, and G.J. Boulnois Nucleotide sequence of the streptolysin O (SLO) gene: structural homologies between SLO and other membrane-damaging, thiol-activated toxins Infect. Immun. 55 1987 3228 3232
-
(1987)
Infect. Immun.
, vol.55
, pp. 3228-3232
-
-
Kehoe, M.A.1
Miller, L.2
Walker, J.A.3
Boulnois, G.J.4
-
25
-
-
0017661629
-
Cellular location of pneumolysin
-
M.K. Johnson Cellular location of pneumolysin FEMS Microbiol. Lett. 2 1977 243 245
-
(1977)
FEMS Microbiol. Lett.
, vol.2
, pp. 243-245
-
-
Johnson, M.K.1
-
26
-
-
0035035231
-
The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin
-
P. Balachandran, S.K. Hollingshead, J.C. Paton, and D.E. Briles The autolytic enzyme LytA of Streptococcus pneumoniae is not responsible for releasing pneumolysin J. Bacteriol. 183 2001 3108 3116
-
(2001)
J. Bacteriol.
, vol.183
, pp. 3108-3116
-
-
Balachandran, P.1
Hollingshead, S.K.2
Paton, J.C.3
Briles, D.E.4
-
27
-
-
64049092852
-
Pneumolysin localizes to the cell wall of Streptococcus pneumoniae
-
K.E. Price, and A. Camilli Pneumolysin localizes to the cell wall of Streptococcus pneumoniae J. Bacteriol. 191 2009 2163 2168
-
(2009)
J. Bacteriol.
, vol.191
, pp. 2163-2168
-
-
Price, K.E.1
Camilli, A.2
-
28
-
-
46949109372
-
Characterization of a streptococcal cholesterol-dependent cytolysin with a Lewis y and b specific lectin domain
-
S. Farrand, E. Hotze, P. Friese, S.K. Hollingshead, D.F. Smith, R.D. Cummings, G.L. Dale, and R.K. Tweten Characterization of a streptococcal cholesterol-dependent cytolysin with a Lewis y and b specific lectin domain Biochemistry 47 2008 7097 7107
-
(2008)
Biochemistry
, vol.47
, pp. 7097-7107
-
-
Farrand, S.1
Hotze, E.2
Friese, P.3
Hollingshead, S.K.4
Smith, D.F.5
Cummings, R.D.6
Dale, G.L.7
Tweten, R.K.8
-
29
-
-
0034602312
-
A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity
-
A.L. Decatur, and D.A. Portnoy A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity Science 290 2000 992 995
-
(2000)
Science
, vol.290
, pp. 992-995
-
-
Decatur, A.L.1
Portnoy, D.A.2
-
30
-
-
35648954603
-
Listeriolysin O secreted by Listeria monocytogenes into the host cell cytosol is degraded by the N-end rule pathway
-
P. Schnupf, J. Zhou, A. Varshavsky, and D.A. Portnoy Listeriolysin O secreted by Listeria monocytogenes into the host cell cytosol is degraded by the N-end rule pathway Infect. Immun. 75 2007 5135 5147
-
(2007)
Infect. Immun.
, vol.75
, pp. 5135-5147
-
-
Schnupf, P.1
Zhou, J.2
Varshavsky, A.3
Portnoy, D.A.4
-
31
-
-
3042611531
-
Specificity of streptolysin O in cytolysin-mediated translocation
-
M.A. Meehl, and M.G. Caparon Specificity of streptolysin O in cytolysin-mediated translocation Mol. Microbiol. 52 2004 1665 1676
-
(2004)
Mol. Microbiol.
, vol.52
, pp. 1665-1676
-
-
Meehl, M.A.1
Caparon, M.G.2
-
32
-
-
0030666371
-
Structure of a cholesterol-binding thiol-activated cytolysin and a model of its membrane form
-
J. Rossjohn, S.C. Feil, W.J. McKinstry, R.K. Tweten, and M.W. Parker Structure of a cholesterol-binding thiol-activated cytolysin and a model of its membrane form Cell 89 1997 685 692
-
(1997)
Cell
, vol.89
, pp. 685-692
-
-
Rossjohn, J.1
Feil, S.C.2
McKinstry, W.J.3
Tweten, R.K.4
Parker, M.W.5
-
33
-
-
14144251524
-
Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin
-
G. Polekhina, K.S. Giddings, R.K. Tweten, and M.W. Parker Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin Proc. Natl. Acad. Sci. 102 2005 600 605
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 600-605
-
-
Polekhina, G.1
Giddings, K.S.2
Tweten, R.K.3
Parker, M.W.4
-
34
-
-
67649743349
-
Cellular functions and X-ray structure of anthrolysin O, a cholesterol-dependent cytolysin secreted by Bacillus anthracis
-
R.W. Bourdeau, E. Malito, A. Chenal, B.L. Bishop, M.W. Musch, M.L. Villereal, E.B. Chang, E.M. Mosser, R.F. Rest, and W.J. Tang Cellular functions and X-ray structure of anthrolysin O, a cholesterol-dependent cytolysin secreted by Bacillus anthracis J. Biol. Chem. 284 2009 14645 14656
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 14645-14656
-
-
Bourdeau, R.W.1
Malito, E.2
Chenal, A.3
Bishop, B.L.4
Musch, M.W.5
Villereal, M.L.6
Chang, E.B.7
Mosser, E.M.8
Rest, R.F.9
Tang, W.J.10
-
35
-
-
79953148352
-
Crystal structure of cytotoxin protein suilysin from Streptococcus suis
-
L. Xu, B. Huang, H. Du, X.C. Zhang, J. Xu, X. Li, and Z. Rao Crystal structure of cytotoxin protein suilysin from Streptococcus suis Protein Cell 1 2010 96 105
-
(2010)
Protein Cell
, vol.1
, pp. 96-105
-
-
Xu, L.1
Huang, B.2
Du, H.3
Zhang, X.C.4
Xu, J.5
Li, X.6
Rao, Z.7
-
36
-
-
0028988973
-
Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: Change in the aromatic side chains upon binding and insertion
-
M. Nakamura, N. Sekino, M. Iwamoto, and Y. Ohno-Iwashita Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion Biochemistry 34 1995 6513 6520
-
(1995)
Biochemistry
, vol.34
, pp. 6513-6520
-
-
Nakamura, M.1
Sekino, N.2
Iwamoto, M.3
Ohno-Iwashita, Y.4
-
37
-
-
16544370492
-
Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin
-
K.S. Giddings, J. Zhao, P.J. Sims, and R.K. Tweten Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin Nat. Struct. Mol. Biol. 11 2004 1173 1178
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 1173-1178
-
-
Giddings, K.S.1
Zhao, J.2
Sims, P.J.3
Tweten, R.K.4
-
38
-
-
44349190402
-
Functional and phylogenetic characterization of vaginolysin, the human-specific cytolysin from Gardnerella vaginalis
-
S.E. Gelber, J.L. Aguilar, K.L. Lewis, and A.J. Ratner Functional and phylogenetic characterization of vaginolysin, the human-specific cytolysin from Gardnerella vaginalis J. Bacteriol. 190 2008 3896 3903
-
(2008)
J. Bacteriol.
, vol.190
, pp. 3896-3903
-
-
Gelber, S.E.1
Aguilar, J.L.2
Lewis, K.L.3
Ratner, A.J.4
-
39
-
-
67649819389
-
Intermedilysin-receptor interactions during assembly of the pore complex: Assembly intermediates increase host cell susceptibility to complement-mediated lysis
-
S. LaChapelle, R.K. Tweten, and E.M. Hotze Intermedilysin-receptor interactions during assembly of the pore complex: assembly intermediates increase host cell susceptibility to complement-mediated lysis J. Biol. Chem. 284 2009 12719 12726
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12719-12726
-
-
Lachapelle, S.1
Tweten, R.K.2
Hotze, E.M.3
-
40
-
-
77749292162
-
Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface
-
A.J. Farrand, S. LaChapelle, E.M. Hotze, A.E. Johnson, and R.K. Tweten Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface Proc. Natl. Acad. Sci. U. S. A. 107 2010 4341 4346
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 4341-4346
-
-
Farrand, A.J.1
Lachapelle, S.2
Hotze, E.M.3
Johnson, A.E.4
Tweten, R.K.5
-
41
-
-
0141706347
-
Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins
-
K.S. Giddings, A.E. Johnson, and R.K. Tweten Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins Proc. Natl. Acad. Sci. U. S. A. 100 2003 11315 11320
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 11315-11320
-
-
Giddings, K.S.1
Johnson, A.E.2
Tweten, R.K.3
-
42
-
-
0036830653
-
Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin
-
R. Ramachandran, A.P. Heuck, R.K. Tweten, and A.E. Johnson Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin Nat. Struct. Biol. 9 2002 823 827
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 823-827
-
-
Ramachandran, R.1
Heuck, A.P.2
Tweten, R.K.3
Johnson, A.E.4
-
43
-
-
0043234285
-
Assembly and topography of the prepore complex in cholesterol-dependent cytolysins
-
A.P. Heuck, R.K. Tweten, and A.E. Johnson Assembly and topography of the prepore complex in cholesterol-dependent cytolysins J. Biol. Chem. 278 2003 31218 31225
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31218-31225
-
-
Heuck, A.P.1
Tweten, R.K.2
Johnson, A.E.3
-
44
-
-
18844417932
-
The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation
-
R. Ramachandran, R.K. Tweten, and A.E. Johnson The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation Proc. Natl. Acad. Sci. 102 2005 7139 7144
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 7139-7144
-
-
Ramachandran, R.1
Tweten, R.K.2
Johnson, A.E.3
-
45
-
-
4444291857
-
Vertical collapse of a cytolysin prepore moves its transmembrane β-hairpins to the membrane
-
D.M. Czajkowsky, E.M. Hotze, Z. Shao, and R.K. Tweten Vertical collapse of a cytolysin prepore moves its transmembrane β-hairpins to the membrane EMBO J. 23 2004 3206 3215
-
(2004)
EMBO J.
, vol.23
, pp. 3206-3215
-
-
Czajkowsky, D.M.1
Hotze, E.M.2
Shao, Z.3
Tweten, R.K.4
-
46
-
-
3543016107
-
Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit β-strand alignment
-
R. Ramachandran, R.K. Tweten, and A.E. Johnson Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit β-strand alignment Nat. Struct. Mol. Biol. 11 2004 697 705
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 697-705
-
-
Ramachandran, R.1
Tweten, R.K.2
Johnson, A.E.3
-
47
-
-
0037192791
-
Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin
-
E.M. Hotze, A.P. Heuck, D.M. Czajkowsky, Z. Shao, A.E. Johnson, and R.K. Tweten Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin J. Biol. Chem. 277 2002 11597 11605
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11597-11605
-
-
Hotze, E.M.1
Heuck, A.P.2
Czajkowsky, D.M.3
Shao, Z.4
Johnson, A.E.5
Tweten, R.K.6
-
48
-
-
0035896507
-
Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate
-
E.M. Hotze, E.M. Wilson-Kubalek, J. Rossjohn, M.W. Parker, A.E. Johnson, and R.K. Tweten Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate J. Biol. Chem. 276 2001 8261 8268
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 8261-8268
-
-
Hotze, E.M.1
Wilson-Kubalek, E.M.2
Rossjohn, J.3
Parker, M.W.4
Johnson, A.E.5
Tweten, R.K.6
-
49
-
-
0034702810
-
The mechanism of assembly and insertion of the membrane complex of the cholesterol-dependent cytolysin perfringolysin O: Formation of a large prepore complex
-
L.A. Shepard, O. Shatursky, A.E. Johnson, and R.K. Tweten The mechanism of assembly and insertion of the membrane complex of the cholesterol-dependent cytolysin perfringolysin O: formation of a large prepore complex Biochemistry 39 2000 10284 10293
-
(2000)
Biochemistry
, vol.39
, pp. 10284-10293
-
-
Shepard, L.A.1
Shatursky, O.2
Johnson, A.E.3
Tweten, R.K.4
-
50
-
-
0033615736
-
The mechanism of membrane insertion for a cholesterol dependent cytolysin: A novel paradigm for pore-forming toxins
-
O. Shatursky, A.P. Heuck, L.A. Shepard, J. Rossjohn, M.W. Parker, A.E. Johnson, and R.K. Tweten The mechanism of membrane insertion for a cholesterol dependent cytolysin: a novel paradigm for pore-forming toxins Cell 99 1999 293 299
-
(1999)
Cell
, vol.99
, pp. 293-299
-
-
Shatursky, O.1
Heuck, A.P.2
Shepard, L.A.3
Rossjohn, J.4
Parker, M.W.5
Johnson, A.E.6
Tweten, R.K.7
-
51
-
-
0032514655
-
Identification of a membrane-spanning domain of the thiol-activated pore-forming toxin Clostridium perfringens perfringolysin O: An α-helical to β-sheet transition identified by fluorescence spectroscopy
-
L.A. Shepard, A.P. Heuck, B.D. Hamman, J. Rossjohn, M.W. Parker, K.R. Ryan, A.E. Johnson, and R.K. Tweten Identification of a membrane-spanning domain of the thiol-activated pore-forming toxin Clostridium perfringens perfringolysin O: an α-helical to β-sheet transition identified by fluorescence spectroscopy Biochemistry 37 1998 14563 14574
-
(1998)
Biochemistry
, vol.37
, pp. 14563-14574
-
-
Shepard, L.A.1
Heuck, A.P.2
Hamman, B.D.3
Rossjohn, J.4
Parker, M.W.5
Ryan, K.R.6
Johnson, A.E.7
Tweten, R.K.8
-
52
-
-
0033735354
-
Cholesterol-binding cytolytic protein toxins
-
J.E. Alouf Cholesterol-binding cytolytic protein toxins Int. J. Med. Microbiol. 290 2000 351 356
-
(2000)
Int. J. Med. Microbiol.
, vol.290
, pp. 351-356
-
-
Alouf, J.E.1
-
53
-
-
0005777353
-
Interaction of streptolysin O with sterols
-
D. Prigent, and J.E. Alouf Interaction of streptolysin O with sterols Biochem. Biophys. Acta 433 1976 422 428
-
(1976)
Biochem. Biophys. Acta
, vol.433
, pp. 422-428
-
-
Prigent, D.1
Alouf, J.E.2
-
54
-
-
0018917907
-
Binding of cholesterol by sulfhydryl-activated cytolysins
-
M.K. Johnson, C. Geoffroy, and J.E. Alouf Binding of cholesterol by sulfhydryl-activated cytolysins Infect. Immun. 27 1980 97 101
-
(1980)
Infect. Immun.
, vol.27
, pp. 97-101
-
-
Johnson, M.K.1
Geoffroy, C.2
Alouf, J.E.3
-
55
-
-
0023656177
-
Role of the essential thiol group in the thiol-activated cytolysin from Clostridium perfringens
-
M. Iwamoto, Y. Ohno-Iwashita, and S. Ando Role of the essential thiol group in the thiol-activated cytolysin from Clostridium perfringens Eur. J. Biochem. 167 1987 425 430
-
(1987)
Eur. J. Biochem.
, vol.167
, pp. 425-430
-
-
Iwamoto, M.1
Ohno-Iwashita, Y.2
Ando, S.3
-
56
-
-
0024294330
-
Effect of perfringolysin O on the lateral diffusion constant of membrane proteins of hepatocytes as revealed by fluorescence recovery after photobleaching
-
I. Nagy, Y. Ohno-Iwashita, M. Ohta, V. Nagy, K. Kitani, S. Ando, and K. Imahori Effect of perfringolysin O on the lateral diffusion constant of membrane proteins of hepatocytes as revealed by fluorescence recovery after photobleaching Biochim. Biophys. Acta 939 1988 551 560
-
(1988)
Biochim. Biophys. Acta
, vol.939
, pp. 551-560
-
-
Nagy, I.1
Ohno-Iwashita, Y.2
Ohta, M.3
Nagy, V.4
Kitani, K.5
Ando, S.6
Imahori, K.7
-
57
-
-
0023783454
-
Protease nicked θ-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes
-
Y. Ohno-Iwashita, M. Iwamoto, K. Mitsui, S. Ando, and Y. Nagai Protease nicked θ-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes Eur. J. Biochem. 176 1988 95 101
-
(1988)
Eur. J. Biochem.
, vol.176
, pp. 95-101
-
-
Ohno-Iwashita, Y.1
Iwamoto, M.2
Mitsui, K.3
Ando, S.4
Nagai, Y.5
-
58
-
-
0025355631
-
A modified q-toxin produced by limited proteolysis and methylation: A probe for the functional study of membrane cholesterol
-
Y. Ohno-Iwashita, M. Iwamoto, S. Ando, K. Mitsui, and S. Iwashita A modified q-toxin produced by limited proteolysis and methylation: a probe for the functional study of membrane cholesterol Biochim. Biophys. Acta 1023 1990 441 448
-
(1990)
Biochim. Biophys. Acta
, vol.1023
, pp. 441-448
-
-
Ohno-Iwashita, Y.1
Iwamoto, M.2
Ando, S.3
Mitsui, K.4
Iwashita, S.5
-
59
-
-
0025880182
-
A cytolysin, theta-toxin, preferentially binds to membrane cholesterol surrounded by phospholipids with 18-carbon hydrocarbon chains in cholesterol-rich region
-
Y. Ohno-Iwashita, M. Iwamoto, K. Mitsui, S. Ando, and S. Iwashita A cytolysin, theta-toxin, preferentially binds to membrane cholesterol surrounded by phospholipids with 18-carbon hydrocarbon chains in cholesterol-rich region J. Biochem. (Tokyo) 110 1991 369 375
-
(1991)
J. Biochem. (Tokyo)
, vol.110
, pp. 369-375
-
-
Ohno-Iwashita, Y.1
Iwamoto, M.2
Mitsui, K.3
Ando, S.4
Iwashita, S.5
-
60
-
-
0026785987
-
Effect of lipidic factors on membrane cholesterol topology-mode of binding of theta-toxin to cholesterol in liposomes
-
Y. Ohno-Iwashita, M. Iwamoto, S. Ando, and S. Iwashita Effect of lipidic factors on membrane cholesterol topology-mode of binding of theta-toxin to cholesterol in liposomes Biochim. Biophys. Acta 1109 1992 81 90
-
(1992)
Biochim. Biophys. Acta
, vol.1109
, pp. 81-90
-
-
Ohno-Iwashita, Y.1
Iwamoto, M.2
Ando, S.3
Iwashita, S.4
-
61
-
-
0027421775
-
Membrane disorganization induced by perfringolysin O (theta-toxin) of Clostridium perfringens - Effect of toxin binding and self-assembly on liposomes
-
M. Iwamoto, M. Nakamura, K. Mitsui, S. Ando, and Y. Ohno-Iwashita Membrane disorganization induced by perfringolysin O (theta-toxin) of Clostridium perfringens - effect of toxin binding and self-assembly on liposomes Biochim. Biophys. Acta 1153 1993 89 96
-
(1993)
Biochim. Biophys. Acta
, vol.1153
, pp. 89-96
-
-
Iwamoto, M.1
Nakamura, M.2
Mitsui, K.3
Ando, S.4
Ohno-Iwashita, Y.5
-
62
-
-
0029972377
-
Contribution of individual tryptophan residues to the structure and activity of theta-toxin (perfringolysin o), a cholesterol-binding cytolysin
-
N. Sekino-Suzuki, M. Nakamura, K.I. Mitsui, and Y. Ohno-Iwashita Contribution of individual tryptophan residues to the structure and activity of theta-toxin (perfringolysin o), a cholesterol-binding cytolysin Eur. J. Biochem. 241 1996 941 947
-
(1996)
Eur. J. Biochem.
, vol.241
, pp. 941-947
-
-
Sekino-Suzuki, N.1
Nakamura, M.2
Mitsui, K.I.3
Ohno-Iwashita, Y.4
-
63
-
-
0030746612
-
A biotinylated perfringolysin O derivative: A new probe for detection of cell surface cholesterol
-
M. Iwamoto, I. Morita, M. Fukuda, S. Murota, S. Ando, and Y. Ohno-Iwashita A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol Biochim. Biophys. Acta 1327 1997 222 230
-
(1997)
Biochim. Biophys. Acta
, vol.1327
, pp. 222-230
-
-
Iwamoto, M.1
Morita, I.2
Fukuda, M.3
Murota, S.4
Ando, S.5
Ohno-Iwashita, Y.6
-
64
-
-
0031749207
-
Contribution of tryptophan residues to the structural changes in perfringolysin O during interaction with liposomal membranes
-
M. Nakamura, N. Sekino-Suzuki, K. Mitsui, and Y. Ohno-Iwashita Contribution of tryptophan residues to the structural changes in perfringolysin O during interaction with liposomal membranes J. Biochem. (Tokyo) 123 1998 1145 1155
-
(1998)
J. Biochem. (Tokyo)
, vol.123
, pp. 1145-1155
-
-
Nakamura, M.1
Sekino-Suzuki, N.2
Mitsui, K.3
Ohno-Iwashita, Y.4
-
65
-
-
0032858797
-
The conserved undecapeptide shared by thiol-activated cytolysins is involved in membrane binding
-
T. Jacobs, M.D. Cima-Cabal, A. Darji, F.J. Mendez, F. Vazquez, A.A. Jacobs, Y. Shimada, Y. Ohno-Iwashita, S. Weiss, and J.R. de los Toyos The conserved undecapeptide shared by thiol-activated cytolysins is involved in membrane binding FEBS Lett. 459 1999 463 466
-
(1999)
FEBS Lett.
, vol.459
, pp. 463-466
-
-
Jacobs, T.1
Cima-Cabal, M.D.2
Darji, A.3
Mendez, F.J.4
Vazquez, F.5
Jacobs, A.A.6
Shimada, Y.7
Ohno-Iwashita, Y.8
Weiss, S.9
De Los Toyos, J.R.10
-
66
-
-
0035942169
-
Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts)
-
A.A. Waheed, Y. Shimada, H.F. Heijnen, M. Nakamura, M. Inomata, M. Hayashi, S. Iwashita, J.W. Slot, and Y. Ohno-Iwashita Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts) Proc. Natl. Acad. Sci. U. S. A. 98 2001 4926 4931
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 4926-4931
-
-
Waheed, A.A.1
Shimada, Y.2
Heijnen, H.F.3
Nakamura, M.4
Inomata, M.5
Hayashi, M.6
Iwashita, S.7
Slot, J.W.8
Ohno-Iwashita, Y.9
-
67
-
-
18744391355
-
The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains
-
Y. Shimada, M. Maruya, S. Iwashita, and Y. Ohno-Iwashita The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains Eur. J. Biochem. 269 2002 6195 6203
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 6195-6203
-
-
Shimada, Y.1
Maruya, M.2
Iwashita, S.3
Ohno-Iwashita, Y.4
-
68
-
-
0023783454
-
Protease-nicked theta-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes
-
Y. Ohno-Iwashita, M. Iwamoto, K. Mitsui, S. Ando, and Y. Nagai Protease-nicked theta-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes Eur. J. Biochem. 176 1988 95 101
-
(1988)
Eur. J. Biochem.
, vol.176
, pp. 95-101
-
-
Ohno-Iwashita, Y.1
Iwamoto, M.2
Mitsui, K.3
Ando, S.4
Nagai, Y.5
-
69
-
-
0033636662
-
Mechanism of membrane insertion of a multimeric b-barrel protein: Perfringolysin O creates a pore using ordered and coupled conformational changes
-
A.P. Heuck, E. Hotze, R.K. Tweten, and A.E. Johnson Mechanism of membrane insertion of a multimeric b-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes Mol. Cell 6 2000 1233 1242
-
(2000)
Mol. Cell
, vol.6
, pp. 1233-1242
-
-
Heuck, A.P.1
Hotze, E.2
Tweten, R.K.3
Johnson, A.E.4
-
70
-
-
66149142747
-
Cholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O binding
-
J.J. Flanagan, R.K. Tweten, A.E. Johnson, and A.P. Heuck Cholesterol exposure at the membrane surface is necessary and sufficient to trigger perfringolysin O binding Biochemistry 48 2009 3977 3987
-
(2009)
Biochemistry
, vol.48
, pp. 3977-3987
-
-
Flanagan, J.J.1
Tweten, R.K.2
Johnson, A.E.3
Heuck, A.P.4
-
71
-
-
0020422130
-
Structural characteristics of tetanolysin and its binding to lipid vesicles
-
S. Rottem, R.M. Cole, W.H. Habig, M.F. Barile, and M.C. Hardegree Structural characteristics of tetanolysin and its binding to lipid vesicles J. Bacteriol. 152 1982 888 892
-
(1982)
J. Bacteriol.
, vol.152
, pp. 888-892
-
-
Rottem, S.1
Cole, R.M.2
Habig, W.H.3
Barile, M.F.4
Hardegree, M.C.5
-
72
-
-
41949085510
-
How interaction of perfringolysin O with membranes is controlled by sterol structure, lipid structure, and physiological low pH: Insights into the origin of perfringolysin O-lipid raft interaction
-
L.D. Nelson, A.E. Johnson, and E. London How interaction of perfringolysin O with membranes is controlled by sterol structure, lipid structure, and physiological low pH: insights into the origin of perfringolysin O-lipid raft interaction J. Biol. Chem. 283 2008 4632 4642
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 4632-4642
-
-
Nelson, L.D.1
Johnson, A.E.2
London, E.3
-
73
-
-
0142231450
-
Differential interaction of the two cholesterol-dependent, membrane-damaging toxins, streptolysin O and Vibrio cholerae cytolysin, with enantiomeric cholesterol
-
A. Zitzer, E.J. Westover, D.F. Covey, and M. Palmer Differential interaction of the two cholesterol-dependent, membrane-damaging toxins, streptolysin O and Vibrio cholerae cytolysin, with enantiomeric cholesterol FEBS Lett. 553 2003 229 231
-
(2003)
FEBS Lett.
, vol.553
, pp. 229-231
-
-
Zitzer, A.1
Westover, E.J.2
Covey, D.F.3
Palmer, M.4
-
74
-
-
0025244264
-
Effect of isolated C-terminal fragment of theta-toxin (perfringolysin-O) on toxin assembly and membrane lysis
-
M. Iwamoto, Y. Ohno-Iwashita, and S. Ando Effect of isolated C-terminal fragment of theta-toxin (perfringolysin-O) on toxin assembly and membrane lysis Eur. J. Biochem. 194 1990 25 31
-
(1990)
Eur. J. Biochem.
, vol.194
, pp. 25-31
-
-
Iwamoto, M.1
Ohno-Iwashita, Y.2
Ando, S.3
-
75
-
-
0033603558
-
C-terminal amino acid residues are required for the folding and cholesterol binding property of perfringolysin O, a pore-forming cytolysin
-
Y. Shimada, M. Nakamura, Y. Naito, K. Nomura, and Y. Ohno-Iwashita C-terminal amino acid residues are required for the folding and cholesterol binding property of perfringolysin O, a pore-forming cytolysin J. Biol. Chem. 274 1999 18536 18542
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 18536-18542
-
-
Shimada, Y.1
Nakamura, M.2
Naito, Y.3
Nomura, K.4
Ohno-Iwashita, Y.5
-
76
-
-
0025821214
-
Isolation of a tryptic fragment from Clostridium perfringens q-toxin that contains sites for membrane binding and self-aggregation
-
R.K. Tweten, R.W. Harris, and P.J. Sims Isolation of a tryptic fragment from Clostridium perfringens q-toxin that contains sites for membrane binding and self-aggregation J. Biol. Chem. 266 1991 12449 12454
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 12449-12454
-
-
Tweten, R.K.1
Harris, R.W.2
Sims, P.J.3
-
77
-
-
34447536854
-
Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin
-
C.E. Soltani, E.M. Hotze, A.E. Johnson, and R.K. Tweten Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin J. Biol. Chem. 282 2007 15709 15716
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 15709-15716
-
-
Soltani, C.E.1
Hotze, E.M.2
Johnson, A.E.3
Tweten, R.K.4
-
78
-
-
38049125626
-
Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions
-
C.E. Soltani, E.M. Hotze, A.E. Johnson, and R.K. Tweten Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions Proc. Natl. Acad. Sci. U. S. A. 104 2007 20226 20231
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 20226-20231
-
-
Soltani, C.E.1
Hotze, E.M.2
Johnson, A.E.3
Tweten, R.K.4
-
79
-
-
0030037295
-
Intermedilysin, a novel cytotoxin specific for human cells secreted by Streptococcus intermedius UNS46 isolated from a human liver abscess
-
H. Nagamune, C. Ohnishi, A. Katsuura, K. Fushitani, R.A. Whiley, A. Tsuji, and Y. Matsuda Intermedilysin, a novel cytotoxin specific for human cells secreted by Streptococcus intermedius UNS46 isolated from a human liver abscess Infect. Immun. 64 1996 3093 3100
-
(1996)
Infect. Immun.
, vol.64
, pp. 3093-3100
-
-
Nagamune, H.1
Ohnishi, C.2
Katsuura, A.3
Fushitani, K.4
Whiley, R.A.5
Tsuji, A.6
Matsuda, Y.7
-
80
-
-
79957978193
-
Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8{alpha} and C9
-
S.E. Wickham, E.M. Hotze, A.J. Farrand, G. Polekhina, T.L. Nero, S. Tomlinson, M.W. Parker, and R.K. Tweten Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8{alpha} and C9 J. Biol. Chem. 286 2011 20952 20962
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 20952-20962
-
-
Wickham, S.E.1
Hotze, E.M.2
Farrand, A.J.3
Polekhina, G.4
Nero, T.L.5
Tomlinson, S.6
Parker, M.W.7
Tweten, R.K.8
-
81
-
-
0025233715
-
The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9
-
S.A. Rollins, and P.J. Sims The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9 J. Immunol. 144 1990 3478 3483
-
(1990)
J. Immunol.
, vol.144
, pp. 3478-3483
-
-
Rollins, S.A.1
Sims, P.J.2
-
82
-
-
0025857372
-
Inhibition of homologous complement by CD59 is mediated by a species-selective recognition conferred through binding to C8 within C5b-8 or C9 within C5b-9
-
S.A. Rollins, J. Zhao, H. Ninomiya, and P.J. Sims Inhibition of homologous complement by CD59 is mediated by a species-selective recognition conferred through binding to C8 within C5b-8 or C9 within C5b-9 J. Immunol. 146 1991 2345 2351
-
(1991)
J. Immunol.
, vol.146
, pp. 2345-2351
-
-
Rollins, S.A.1
Zhao, J.2
Ninomiya, H.3
Sims, P.J.4
-
83
-
-
0002706313
-
Proteins of the membrane attack complex
-
J.E. Volanakis, M.M. Frank, Marcel Dekker, Inc. New York
-
M.E. Plumb, and J.M. Sodetz Proteins of the membrane attack complex J.E. Volanakis, M.M. Frank, The Human Complement System in Health and Disease vol. 1 1998 Marcel Dekker, Inc. New York 119 148
-
(1998)
The Human Complement System in Health and Disease
, vol.1 VOL.
, pp. 119-148
-
-
Plumb, M.E.1
Sodetz, J.M.2
-
84
-
-
0032536856
-
Assembly mechanism of the oligomeric streptolysin O pore: The early membrane lesion is lined by a free edge of the lipid membrane and is extended gradually during oligomerization
-
M. Palmer, R. Harris, C. Freytag, M. Kehoe, J. Tranum-Jensen, and S. Bhakdi Assembly mechanism of the oligomeric streptolysin O pore: the early membrane lesion is lined by a free edge of the lipid membrane and is extended gradually during oligomerization EMBO J. 17 1998 1598 1605
-
(1998)
EMBO J.
, vol.17
, pp. 1598-1605
-
-
Palmer, M.1
Harris, R.2
Freytag, C.3
Kehoe, M.4
Tranum-Jensen, J.5
Bhakdi, S.6
-
85
-
-
0032987478
-
Membrane protein folding and stability: Physical principles
-
S.H. White, and W.C. Wimley Membrane protein folding and stability: physical principles Annu. Rev. Biophys. Biomol. Struct. 28 1999 319 365
-
(1999)
Annu. Rev. Biophys. Biomol. Struct.
, vol.28
, pp. 319-365
-
-
White, S.H.1
Wimley, W.C.2
-
86
-
-
0030592696
-
Crystallization and preliminary X-ray analysis of a thiol-activated cytolysin
-
S.C. Feil, J. Rossjohn, K. Rohde, R.K. Tweten, and M.W. Parker Crystallization and preliminary X-ray analysis of a thiol-activated cytolysin FEBS Lett. 397 1996 290 292
-
(1996)
FEBS Lett.
, vol.397
, pp. 290-292
-
-
Feil, S.C.1
Rossjohn, J.2
Rohde, K.3
Tweten, R.K.4
Parker, M.W.5
-
87
-
-
34548670476
-
Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense
-
M.A. Hadders, D.X. Beringer, and P. Gros Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense Science 317 2007 1552 1554
-
(2007)
Science
, vol.317
, pp. 1552-1554
-
-
Hadders, M.A.1
Beringer, D.X.2
Gros, P.3
-
88
-
-
78549267766
-
The structural basis for membrane binding and pore formation by lymphocyte perforin
-
R.H. Law, N. Lukoyanova, I. Voskoboinik, T.T. Caradoc-Davies, K. Baran, M.A. Dunstone, M.E. D'Angelo, E.V. Orlova, F. Coulibaly, S. Verschoor, K.A. Browne, A. Ciccone, M.J. Kuiper, P.I. Bird, J.A. Trapani, H.R. Saibil, and J.C. Whisstock The structural basis for membrane binding and pore formation by lymphocyte perforin Nature 468 2010 447 451
-
(2010)
Nature
, vol.468
, pp. 447-451
-
-
Law, R.H.1
Lukoyanova, N.2
Voskoboinik, I.3
Caradoc-Davies, T.T.4
Baran, K.5
Dunstone, M.A.6
D'Angelo, M.E.7
Orlova, E.V.8
Coulibaly, F.9
Verschoor, S.10
Browne, K.A.11
Ciccone, A.12
Kuiper, M.J.13
Bird, P.I.14
Trapani, J.A.15
Saibil, H.R.16
Whisstock, J.C.17
-
89
-
-
34548666167
-
A common fold mediates vertebrate defense and bacterial attack
-
C.J. Rosado, A.M. Buckle, R.H. Law, R.E. Butcher, W.T. Kan, C.H. Bird, K. Ung, K.A. Browne, K. Baran, T.A. Bashtannyk-Puhalovich, N.G. Faux, W. Wong, C.J. Porter, R.N. Pike, A.M. Ellisdon, M.C. Pearce, S.P. Bottomley, J. Emsley, A.I. Smith, J. Rossjohn, E.L. Hartland, I. Voskoboinik, J.A. Trapani, P.I. Bird, M.A. Dunstone, and J.C. Whisstock A common fold mediates vertebrate defense and bacterial attack Science 317 2007 1548 1551
-
(2007)
Science
, vol.317
, pp. 1548-1551
-
-
Rosado, C.J.1
Buckle, A.M.2
Law, R.H.3
Butcher, R.E.4
Kan, W.T.5
Bird, C.H.6
Ung, K.7
Browne, K.A.8
Baran, K.9
Bashtannyk-Puhalovich, T.A.10
Faux, N.G.11
Wong, W.12
Porter, C.J.13
Pike, R.N.14
Ellisdon, A.M.15
Pearce, M.C.16
Bottomley, S.P.17
Emsley, J.18
Smith, A.I.19
Rossjohn, J.20
Hartland, E.L.21
Voskoboinik, I.22
Trapani, J.A.23
Bird, P.I.24
Dunstone, M.A.25
Whisstock, J.C.26
more..
-
90
-
-
43049094015
-
Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit
-
D.J. Slade, L.L. Lovelace, M. Chruszcz, W. Minor, L. Lebioda, and J.M. Sodetz Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit J. Mol. Biol. 379 2008 331 342
-
(2008)
J. Mol. Biol.
, vol.379
, pp. 331-342
-
-
Slade, D.J.1
Lovelace, L.L.2
Chruszcz, M.3
Minor, W.4
Lebioda, L.5
Sodetz, J.M.6
-
91
-
-
0029909653
-
Membrane-penetrating domain of streptolysin O identified by cysteine scanning mutagenesis
-
M. Palmer, P. Saweljew, I. Vulicevic, A. Valeva, M. Kehoe, and S. Bhakdi Membrane-penetrating domain of streptolysin O identified by cysteine scanning mutagenesis J. Biol. Chem. 271 1996 26664 26667
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 26664-26667
-
-
Palmer, M.1
Saweljew, P.2
Vulicevic, I.3
Valeva, A.4
Kehoe, M.5
Bhakdi, S.6
-
92
-
-
0027169048
-
A ring-shaped structure with a crown formed by streptolysin-O on the erythrocyte membrane
-
K. Sekiya, R. Satoh, H. Danbara, and Y. Futaesaku A ring-shaped structure with a crown formed by streptolysin-O on the erythrocyte membrane J. Bacteriol. 175 1993 5953 5961
-
(1993)
J. Bacteriol.
, vol.175
, pp. 5953-5961
-
-
Sekiya, K.1
Satoh, R.2
Danbara, H.3
Futaesaku, Y.4
-
93
-
-
0018789078
-
Ring formation of perfringolysin O as revealed by negative stain electron microscopy
-
K. Mitsui, T. Sekiya, S. Okamura, Y. Nozawa, and J. Hase Ring formation of perfringolysin O as revealed by negative stain electron microscopy Biochim. Biophys. Acta 558 1979 307 313
-
(1979)
Biochim. Biophys. Acta
, vol.558
, pp. 307-313
-
-
Mitsui, K.1
Sekiya, T.2
Okamura, S.3
Nozawa, Y.4
Hase, J.5
-
94
-
-
0031776879
-
Listeriolysin O: Cholesterol inhibits cytolysis but not binding to cellular membranes
-
T. Jacobs, A. Darji, N. Frahm, M. Rohde, J. Wehland, T. Chakraborty, and S. Weiss Listeriolysin O: cholesterol inhibits cytolysis but not binding to cellular membranes Mol. Microbiol. 28 1998 1081 1089
-
(1998)
Mol. Microbiol.
, vol.28
, pp. 1081-1089
-
-
Jacobs, T.1
Darji, A.2
Frahm, N.3
Rohde, M.4
Wehland, J.5
Chakraborty, T.6
Weiss, S.7
-
95
-
-
33947163269
-
Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins
-
J. Rossjohn, G. Polekhina, S.C. Feil, C.J. Morton, R.K. Tweten, and M.W. Parker Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins J. Mol. Biol. 367 2007 1227-1223
-
(2007)
J. Mol. Biol.
, vol.367
, pp. 1227-1223
-
-
Rossjohn, J.1
Polekhina, G.2
Feil, S.C.3
Morton, C.J.4
Tweten, R.K.5
Parker, M.W.6
-
96
-
-
17444405610
-
Structural basis of pore formation by the bacterial toxin pneumolysin
-
S.J. Tilley, E.V. Orlova, R.J. Gilbert, P.W. Andrew, and H.R. Saibil Structural basis of pore formation by the bacterial toxin pneumolysin Cell 121 2005 247 256
-
(2005)
Cell
, vol.121
, pp. 247-256
-
-
Tilley, S.J.1
Orlova, E.V.2
Gilbert, R.J.3
Andrew, P.W.4
Saibil, H.R.5
-
97
-
-
0023189876
-
Purification, characterization, and toxicity of the sulfhydryl-activated hemolysin listeriolysin O from Listeria monocytogenes
-
C. Geoffroy, J.L. Gaillard, J.E. Alouf, and P. Berche Purification, characterization, and toxicity of the sulfhydryl-activated hemolysin listeriolysin O from Listeria monocytogenes Infect. Immun. 55 1987 1641 1646
-
(1987)
Infect. Immun.
, vol.55
, pp. 1641-1646
-
-
Geoffroy, C.1
Gaillard, J.L.2
Alouf, J.E.3
Berche, P.4
-
98
-
-
0036199706
-
Molecular and cellular basis of the infection by Listeria monocytogenes: An overview
-
P. Cossart Molecular and cellular basis of the infection by Listeria monocytogenes: an overview Int. J. Med. Microbiol. 291 2002 401 409
-
(2002)
Int. J. Med. Microbiol.
, vol.291
, pp. 401-409
-
-
Cossart, P.1
-
99
-
-
0036327382
-
The cell biology of Listeria monocytogenes infection: The intersection of bacterial pathogenesis and cell-mediated immunity
-
D.A. Portnoy, V. Auerbuch, and I.J. Glomski The cell biology of Listeria monocytogenes infection: the intersection of bacterial pathogenesis and cell-mediated immunity J. Cell Biol. 158 2002 409 414
-
(2002)
J. Cell Biol.
, vol.158
, pp. 409-414
-
-
Portnoy, D.A.1
Auerbuch, V.2
Glomski, I.J.3
-
100
-
-
33744948764
-
Listeriolysin O: A key protein of Listeria monocytogenes with multiple functions
-
S. Kayal, and A. Charbit Listeriolysin O: a key protein of Listeria monocytogenes with multiple functions FEMS Microbiol. Rev. 30 2006 514 529
-
(2006)
FEMS Microbiol. Rev.
, vol.30
, pp. 514-529
-
-
Kayal, S.1
Charbit, A.2
-
101
-
-
0025329666
-
Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells
-
J. Bielecki, P. Youngman, P. Connelly, and D.A. Portnoy Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells Nature 345 1990 175 176
-
(1990)
Nature
, vol.345
, pp. 175-176
-
-
Bielecki, J.1
Youngman, P.2
Connelly, P.3
Portnoy, D.A.4
-
102
-
-
0026710550
-
The capacity of listeriolysin O, streptolysin O and perfringolysin O to mediate growth of Bacillus subtilis within mammalian cells
-
D.A. Portnoy, R.K. Tweten, M. Kehoe, and J. Bielecki The capacity of listeriolysin O, streptolysin O and perfringolysin O to mediate growth of Bacillus subtilis within mammalian cells Infect. Immun. 60 1992 2710 2717
-
(1992)
Infect. Immun.
, vol.60
, pp. 2710-2717
-
-
Portnoy, D.A.1
Tweten, R.K.2
Kehoe, M.3
Bielecki, J.4
-
103
-
-
0028072474
-
Characterization of Listeria monocytogenes pathogenesis in a strain expressing perfringolysin O in place of listeriolysin O
-
S. Jones, and D.A. Portnoy Characterization of Listeria monocytogenes pathogenesis in a strain expressing perfringolysin O in place of listeriolysin O Infect. Immun. 62 1994 5608 5613
-
(1994)
Infect. Immun.
, vol.62
, pp. 5608-5613
-
-
Jones, S.1
Portnoy, D.A.2
-
104
-
-
0019287379
-
The entry of diphtheria toxin into the mammalian cell cytoplasm: Evidence for lysosomal involvement
-
R.K. Draper, and M.I. Simon The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement J. Cell Biol. 87 1980 849 854
-
(1980)
J. Cell Biol.
, vol.87
, pp. 849-854
-
-
Draper, R.K.1
Simon, M.I.2
-
105
-
-
0019271816
-
Diphtheria toxin entry into cells is facilitated by low pH
-
K. Sandvig, and S. Olsnes Diphtheria toxin entry into cells is facilitated by low pH J. Cell Biol. 87 1980 828 832
-
(1980)
J. Cell Biol.
, vol.87
, pp. 828-832
-
-
Sandvig, K.1
Olsnes, S.2
-
107
-
-
0019824268
-
Effect of ammonium chloride on receptor-mediated uptake of diphtheria toxin by Vero cells
-
R.B. Dorland, J.L. Middlebrook, and S.H. Leppla Effect of ammonium chloride on receptor-mediated uptake of diphtheria toxin by Vero cells Exp. Cell Res. 134 1981 319 327
-
(1981)
Exp. Cell Res.
, vol.134
, pp. 319-327
-
-
Dorland, R.B.1
Middlebrook, J.L.2
Leppla, S.H.3
-
108
-
-
0019819794
-
Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes
-
B.L. Kagan, A. Finkelstein, and M. Colombini Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes Proc. Nat. Acad. Sci. U. S. A. 78 1981 4950 4954
-
(1981)
Proc. Nat. Acad. Sci. U. S. A.
, vol.78
, pp. 4950-4954
-
-
Kagan, B.L.1
Finkelstein, A.2
Colombini, M.3
-
109
-
-
0022397324
-
Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration
-
M.G. Blewitt, L.A. Chung, and E. London Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration Biochemistry 24 1985 5458 5464
-
(1985)
Biochemistry
, vol.24
, pp. 5458-5464
-
-
Blewitt, M.G.1
Chung, L.A.2
London, E.3
-
110
-
-
0000101881
-
Mechanism of membrane translocation by anthrax toxin: Insertion and pore formation by protective antigen
-
R.J. Collier Mechanism of membrane translocation by anthrax toxin: insertion and pore formation by protective antigen J. Appl. Microbiol. 87 1999 283
-
(1999)
J. Appl. Microbiol.
, vol.87
, pp. 283
-
-
Collier, R.J.1
-
112
-
-
0033032511
-
Isolation of a single carboxyl-carboxylate proton binding site in the pore of a cyclic nucleotide-gated channel
-
J.A. Morrill, and R. MacKinnon Isolation of a single carboxyl-carboxylate proton binding site in the pore of a cyclic nucleotide-gated channel J. Gen. Physiol. 114 1999 71 83
-
(1999)
J. Gen. Physiol.
, vol.114
, pp. 71-83
-
-
Morrill, J.A.1
MacKinnon, R.2
-
114
-
-
0033538455
-
A multinuclear NMR study of the active site of an endoglucanase from a strain of Bacillus. Use of Trp residues as structural probes
-
S. Kawaminami, H. Takahashi, S. Ito, Y. Arata, and I. Shimada A multinuclear NMR study of the active site of an endoglucanase from a strain of Bacillus. Use of Trp residues as structural probes J. Biol. Chem. 274 1999 19823 19828
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 19823-19828
-
-
Kawaminami, S.1
Takahashi, H.2
Ito, S.3
Arata, Y.4
Shimada, I.5
-
115
-
-
0028979982
-
Abnormally high pKa of an active-site glutamic acid residue in Bacillus circulans xylanase. The role of electrostatic interactions
-
J. Davoodi, W.W. Wakarchuk, R.L. Campbell, P.R. Carey, and W.K. Surewicz Abnormally high pKa of an active-site glutamic acid residue in Bacillus circulans xylanase. The role of electrostatic interactions Eur. J. Biochem. 232 1995 839 843
-
(1995)
Eur. J. Biochem.
, vol.232
, pp. 839-843
-
-
Davoodi, J.1
Wakarchuk, W.W.2
Campbell, R.L.3
Carey, P.R.4
Surewicz, W.K.5
-
116
-
-
33845199637
-
Perforin-mediated target-cell death and immune homeostasis
-
I. Voskoboinik, M.J. Smyth, and J.A. Trapani Perforin-mediated target-cell death and immune homeostasis Nat. Rev. Immunol. 6 2006 940 952
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 940-952
-
-
Voskoboinik, I.1
Smyth, M.J.2
Trapani, J.A.3
-
117
-
-
48749111836
-
The MACPF/CDC family of pore-forming toxins
-
C.J. Rosado, S. Kondos, T.E. Bull, M.J. Kuiper, R.H. Law, A.M. Buckle, I. Voskoboinik, P.I. Bird, J.A. Trapani, J.C. Whisstock, and M.A. Dunstone The MACPF/CDC family of pore-forming toxins Cell. Microbiol. 10 2008 1765 1774
-
(2008)
Cell. Microbiol.
, vol.10
, pp. 1765-1774
-
-
Rosado, C.J.1
Kondos, S.2
Bull, T.E.3
Kuiper, M.J.4
Law, R.H.5
Buckle, A.M.6
Voskoboinik, I.7
Bird, P.I.8
Trapani, J.A.9
Whisstock, J.C.10
Dunstone, M.A.11
-
118
-
-
0028331322
-
The membrane attack complex of complement. Assembly, structure and cytotoxic activity
-
A.F. Esser The membrane attack complex of complement. Assembly, structure and cytotoxic activity Toxicology 87 1994 229 247
-
(1994)
Toxicology
, vol.87
, pp. 229-247
-
-
Esser, A.F.1
-
119
-
-
65549121526
-
The molecular basis for perforin oligomerization and transmembrane pore assembly
-
K. Baran, M. Dunstone, J. Chia, A. Ciccone, K.A. Browne, C.J. Clarke, N. Lukoyanova, H. Saibil, J.C. Whisstock, I. Voskoboinik, and J.A. Trapani The molecular basis for perforin oligomerization and transmembrane pore assembly Immunity 30 2009 684 695
-
(2009)
Immunity
, vol.30
, pp. 684-695
-
-
Baran, K.1
Dunstone, M.2
Chia, J.3
Ciccone, A.4
Browne, K.A.5
Clarke, C.J.6
Lukoyanova, N.7
Saibil, H.8
Whisstock, J.C.9
Voskoboinik, I.10
Trapani, J.A.11
-
120
-
-
79955953166
-
Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement
-
L.L. Lovelace, C.L. Cooper, J.M. Sodetz, and L. Lebioda Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement J. Biol. Chem. 286 2011 17585 17592
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17585-17592
-
-
Lovelace, L.L.1
Cooper, C.L.2
Sodetz, J.M.3
Lebioda, L.4
-
121
-
-
32044432615
-
Membrane complement regulatory proteins
-
D.D. Kim, and W.C. Song Membrane complement regulatory proteins Clin. Immunol. 118 2006 127 136
-
(2006)
Clin. Immunol.
, vol.118
, pp. 127-136
-
-
Kim, D.D.1
Song, W.C.2
-
122
-
-
33748747546
-
Defining the CD59-C9 binding interaction
-
Y. Huang, F. Qiao, R. Abagyan, S. Hazard, and S. Tomlinson Defining the CD59-C9 binding interaction J. Biol. Chem. 281 2006 27398 27404
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 27398-27404
-
-
Huang, Y.1
Qiao, F.2
Abagyan, R.3
Hazard, S.4
Tomlinson, S.5
-
123
-
-
0029095712
-
Identity of the segment of human complement C8 recognized by complement regulatory protein CD59
-
D.H. Lockert, K.M. Kaufman, C.P. Chang, T. Husler, J.M. Sodetz, and P.J. Sims Identity of the segment of human complement C8 recognized by complement regulatory protein CD59 J. Biol. Chem. 270 1995 19723 19728
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19723-19728
-
-
Lockert, D.H.1
Kaufman, K.M.2
Chang, C.P.3
Husler, T.4
Sodetz, J.M.5
Sims, P.J.6
-
124
-
-
0027999925
-
Identity of a peptide domain of human C9 that is bound by the cell-surface complement inhibitor, CD59
-
C.P. Chang, T. Husler, J. Zhao, T. Wiedmer, and P.J. Sims Identity of a peptide domain of human C9 that is bound by the cell-surface complement inhibitor, CD59 J. Biol. Chem. 269 1994 26424 26430
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26424-26430
-
-
Chang, C.P.1
Husler, T.2
Zhao, J.3
Wiedmer, T.4
Sims, P.J.5
-
125
-
-
0028924871
-
Chimeras of human complement C9 reveal the site recognized by complement regulatory protein CD59
-
T. Husler, D.H. Lockert, K.M. Kaufman, J.M. Sodetz, and P.J. Sims Chimeras of human complement C9 reveal the site recognized by complement regulatory protein CD59 J. Biol. Chem. 270 1995 3483 3486
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3483-3486
-
-
Husler, T.1
Lockert, D.H.2
Kaufman, K.M.3
Sodetz, J.M.4
Sims, P.J.5
|