Characterization of a streptococcal cholesterol-dependent cytolysin with a Lewis y and b specific lectin domain

Biochemistry

Volumn 47, Issue 27, 2008, Pages 7097-7107

  Farrand, Stephen ^a   Hotze, Eileen ^a   Friese, Paul ^a   Hollingshead, Susan K ^b   Smith, David F ^c   Cummings, Richard D ^c   Dale, George L ^a   Tweten, Rodney K ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b University of Alabama at Birmingham   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINATION; AMINES; BLOOD SUBSTITUTES; CHOLESTEROL; MONOMERS; PLATELETS; PORT TERMINALS; SAMARIUM ALLOYS;

BINDING LECTIN; GLYCANS; LEWIS B; MEMBRANE PORES; MICROARRAY ANALYSIS; PLATELET AGGREGATION; PORE-FORMING; PORE-FORMING TOXINS; SCATTERING PROPERTIES; STREPTOCOCCUS INTERMEDIUS; STREPTOCOCCUS PNEUMONIAE; STRUCTURAL CHANGES;

PORE STRUCTURE;

CHOLESTEROL; CYTOLYSIN; GLYCAN; LECTIN; LECTINOLYSIN; PNEUMOLYSIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL GENE; BINDING SITE; BLOOD GROUP LEWIS SYSTEM; CHANNEL GATING; CONTROLLED STUDY; HUMAN; HUMAN CELL; LIGHT SCATTERING; LLY GENE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; STREPTOCOCCUS; STREPTOCOCCUS INTERMEDIUS; STREPTOCOCCUS MITIS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PSEUDOPNEUMONIAE; THROMBOCYTE AGGREGATION;

AMINO ACID SEQUENCE; CHOLESTEROL; CYTOTOXINS; FLUORESCEINS; GENES, BACTERIAL; HEMOLYSIS; HUMANS; LECTINS; LEWIS BLOOD-GROUP SYSTEM; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; PLATELET AGGREGATION; POLYSACCHARIDES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; STREPTOCOCCUS;

STREPTOCOCCUS INTERMEDIUS; STREPTOCOCCUS MITIS; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PSEUDOPNEUMONIAE;

EID: 46949109372     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8005835     Document Type: Article

References (48)

1. Kennedy, M. J., Jackson, M. A., and Kearns, G. L. (2004) Delayed diagnosis of penicillin-resistant Streptococcus mitis endocarditis following single-dose amoxicillin prophylaxis in a child. Clin. Pediatr. (Philadelphia) 43, 773-776.
2. Gowda, R. M., Ansari, A. W., and Khan, I. A. (2003) Complete endocardial cushion defect (complete atrioventricular canal) manifested in adult life by Streptococcus mitis endocarditis of the common atrioventricular valve. Int. J. Cardiol. 89, 109-110.
3. Hall, G. E., and Baddour, L. M. (2002) Apparent failure of endocarditis prophylaxis caused by penicillin-resistant Streptococcus mitis. Am. J. Med. Sci. 324, 51-53.
4. Huang, I. F., Chiou, C. C., Liu, Y. C., and Hsieh, K. S. (2002) Endocarditis caused by penicillin-resistant Streptococcus mitis in a 12-year-old boy, J. Microbiol., Immunol., Infect. (China) 35, 129-132.
5. Lu, H. Z., Weng, X. H., Zhu, B., Li, H., Yin, Y. K., Zhang, Y. X., Haas, D. W., and Tang, Y. W. (2003) Major outbreak of toxic shock-like syndrome caused by Streptococcus mitis. J. Clin. Microbiol. 41, 3051-3055.
6. Jefferies, J., Nieminen, L., Kirkham, L. A., Johnston, C., Smith, A., and Mitchell, T. J. (2007) Identification of a secreted cholesterol-dependent cytolysin (mitilysin) from Streptococcus mitis. J. Bacteriol. 189, 627-632.
7. Ohkuni, H., Todome, Y., Okibayashi, F., Watanabe, Y., Ohtani, N., Ishikawa, T., Asano, G., and Kotani, S. (1997) Purification and partial characterization of a novel human platelet aggregation factor in the extracellular products of Streptococcus mitis, strain Nm-65. FEMS Immunol. Med. Microbiol. 17, 121-129.
8. Ohkuni, H., Todome, Y., Takahashi, H., Nagamune, H., Abe, J., Ohtsuka, H., and Hatakeyama, H. (2006) Antibody titers to Streptococus mitis-derived human platelet aggregation factor (Sm-hPAF) in the sera of patients with Kawasaki disease, in Proceedings of the XVIth Lancefield International Symposium on Streptococci and Streptococcal Diseases (Sriprakash, K. S., Ed.) pp 71-74, Elsevier B.V., Palm Cove, Australia.
9. Nagamune, H., Whiley, R. A., Goto, T., Inai, Y., Maeda, T., Hardie, J. M., and Kourai, H. (2000) Distribution of the intermedilysin gene among the anginosus group streptococci and correlation between intermedilysin production and deep-seated infection with Streptococcus intermedius. J. Clin. Microbiol. 38, 220-226.
10. Bianchet, M. A., Odom, E. W., Vasta, G. R., and Amzel, L. M. (2002) A novel fucose recognition fold involved in innate immunity. Nat. Struct. Biol. 9, 628-634.
11. Majumder, S., Roy, A., and Mandal, C. (2004) Prediction of 3-D structures of fucose-binding proteins and structural analysis of their interaction with ligands. Glycoconjugate J. 20, 545-550.
12. Giddings, K. S., Johnson, A. E., and Tweten, R. K. (2003) Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins. Proc. Natl. Acad. Sci. U.S.A. 100, 11315-11320.
13. Shepard, L. A., Heuck, A. P., Hamman, B. D., Rossjohn, J., Parker, M. W., Ryan, K. R., Johnson, A. E., and Tweten, R. K. (1998) Identification of a membrane-spanning domain of the thiol-activated pore-forming toxin Clostridium perfringens perfringolysin O: an α-helical to β-sheet transition identified by fluorescence spectroscopy. Biochemistry 37, 14563-14574.
14. Soltani, C. E., Hotze, E. M., Johnson, A. E., and Tweten, R. K. (2007) Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin. J. Biol. Chem. 282, 15709-15716.
15. Song, X., Xia, B., Lasanajak, Y., Smith, D. F., and Cummings, R. D. (2008) Quantifiable fluorescent glycan microarrays. Glycoconjugate J. 25, 15-25.
16. Alberio, L., Safa, O., Clemetson, K. J., Esmon, C. T., and Dale, G. L. (2000) Surface expression and functional characterization of alpha-granule factor V in human platelets: effects of ionophore A23187, thrombin, collagen, and convulxin. Blood 95, 1694-1702.
17. Remenyi, G., Szasz, R., Friese, P., and Dale, G. L. (2005) Role of mitochondrial permeability transition pore in coated-platelet formation. Arterioscl., Thromb. Vasc. Biol. 25, 467-471.
18. Shepard, L. A., Shatursky, O., Johnson, A. E., and Tweten, R. K. (2000) The mechanism of assembly and insertion of the membrane complex of the cholesterol-dependent cytolysin perfringolysin O: Formation of a large prepore complex. Biochemistry 39, 10284-10293.
19. Boraston, A. B., Wang, D., and Burke, R. D. (2006) Blood group antigen recognition by a Streptococcus pneumoniae virulence factor. J. Biol. Chem. 281, 35263-35271.
20. Czajkowsky, D. M., Hotze, E. M., Shao, Z., and Tweten, R. K. (2004) Vertical collapse of a cytolysin prepore moves its transmembrane β-hairpins to the membrane. EMBO J. 23, 3206-3215.
21. Harris, R. W., Sims, P. J., and Tweten, R. K. (1991) Kinetic aspects of the aggregation of Clostridium perfringens theta toxin on erythrocyte membranes: A fluorescence energy transfer study. J. Biol. Chem. 266, 6936-6941.
22. Hotze, E. M., Wilson-Kubalek, E. M., Rossjohn, J., Parker, M. W., Johnson, A. E., and Tweten, R. K. (2001) Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate. J. Biol. Chem. 276, 8261-8268.
23. Giddings, K. S., Zhao, J., Sims, P. J., and Tweten, R. K. (2004) Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin. Nat. Struct. Mol. Biol. 12, 1173-1178.
24. Heuck, A. P., Tweten, R. K., and Johnson, A. E. (2003) Assembly and topography of the prepore complex in cholesterol-dependent cytolysins. J. Biol. Chem. 278, 31218-31225.
25. Ramachandran, R., Heuck, A. P., Tweten, R. K., and Johnson, A. E. (2002) Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin. Nat. Struct. Biol. 9, 823-827.
26. Ramachandran, R., Tweten, R. K., and Johnson, A. E. (2005) The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation. Proc. Natl. Acad. Sci. U.S.A. 102, 7139-7144.
27. Tweten, R. K. (2005) The cholesterol-dependent cytolysins; a family of versatile pore-forming toxins. Infect. Immun. 73, 6199-6209.
28. Kawamura, Y., Hou, X. G., Sultana, F., Miura, H., and Ezaki, T. (1995) Determination of 16S rRNA sequences of Streptococcus mitis and Streptococcus gordonii and phylogenetic relationships among members of the genus Streptococcus. Int. J. Syst. Bacteriol. 45, 406-408.
29. Melo, F., and Feytmans, E. (1998) Assessing protein structures with a non-local atomic interaction energy. J. Mol. Biol. 277, 1141-1152.
30. Merritt, E. A., Sixma, T. K., Kalk, K. H., van Zanten, B. A., and Hol, W. G. (1994) Galactose-binding site in Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT). Mol. Microbiol. 13, 745-753.
31. Stein, P. E., Boodhoo, A., Armstrong, G. D., Cockle, S. A., Klein, M. H., and Read, R. J. (1994) The crystal structure of pertussis toxin. Structure 2, 45-57.
32. Olson, R., and Gouaux, E. (2005) Crystal structure of the Vibrio cholerae cytolysin (VCC) pro-toxin and its assembly into a heptameric transmembrane pore. J. Mol. Biol. 350, 997-1016.
33. Clark, G. F., Krivan, H. C., Wilkins, T. D., and Smith, D. F. (1987) Toxin A from Clostridium difficile binds to rabbit erythrocyte glycolipids with terminal Gal alpha 1-3Gal beta 1-4GlcNAc sequences. Arch. Biochem. Biophys. 257, 217-229.
34. Nesic, D., Hsu, Y., and Stebbins, C. E. (2004) Assembly and function of a bacterial genotoxin. Nature 429, 429-433.
35. Tateno, H., and Goldstein, I. J. (2003) Molecular cloning, expression, and characterization of novel hemolytic lectins from the mushroom Laetiporus sulphureus, which show homology to bacterial toxins. J. Biol. Chem. 278, 40455-40463.
36. Rossjohn, J., Buckley, J. T., Hazes, B., Murzin, A. G., Read, R. J., and Parker, M. W. (1997) Aerolysin and pertussis toxin share a common receptor-binding domain. EMBO J. 16, 3426-3434.
37. Hakomori, S. I., and Siddiqui, B. (1974) Isolation and characterization of glycosphingolipid from animal cells and their membranes. Methods Enzymol. 32, 345-367.
38. Marcus, D. M. (1969) The ABO and Lewis blood-group system. Immunochemistry, genetics and relation to human disease. N. Engl. J. Med. 280, 994-1006.
39. Inoue, M., Nakayama, M., and Tanizawa, O. (1990) Altered expression of Lewis blood group and related antigens in fetal, normal adult and malignant tissues of the uterine endometrium. Virchows Arch. 416, 221-228.
40. Heller, D. S., and Thung, S. N. (1990) Expression of Lewis(x) and Lewis(y) blood group related antigens in fetal livers. Pediat. Pathol. 10, 681-687.
41. Jass, J. R., and Roberton, A. M. (1994) Colorectal mucin histochemistry in health and disease: a critical review. Pathol. Int. 44, 487-504.
42. Abe, K., Hakomori, S., and Ohshiba, S. (1986) Differential expression of difucosyl type 2 chain (LeY) defined by monoclonal antibody AH6 in different locations of colonic epithelia, various histological types of colonic polyps, and adenocarcinomas. Cancer Res. 46, 2639-2644.
43. Sakamoto, S., Watanabe, T., Tokumaru, T., Takagi, H., Nakazato, H., and Lloyd, K. O. (1989) Expression of Lewisa, Lewisb, Lewisx, Lewisy, siayl-Lewisa, and sialyl-Lewisx blood group antigens in human gastric carcinoma and in normal gastric tissue. Cancer Res. 49, 745-752.
44. Appelmelk, B. J., Simoons-Smit, I., Negrini, R., Moran, A. P., Aspinall, G. O., Forte, J. G., DeVries, T., Quan, H., Verboom, T., Maaskant, J. J., Ghiara, P., Kuipers, E. J., Bloemena, E., Tadema, T. M., Townsend, R. R., Tyagarajan, K., Crothers, J. M., Jr., Monteiro, M. A., Savio, A., and DeGraaff, J. (1996) Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity. Infect. Immun. 64, 2031-2040.
45. Dettke, M., Palfi, G., and Loibner, H. (2000) Activation-dependent expression of the blood group-related lewis Y antigen on peripheral blood granulocytes. J. Leukocyte Biol. 68, 511-514.
46. Dettke, M., Palfi, G., Pursch, E., Fischer, M. B., and Loibner, H. (2001) Increased expression of the blood group-related Lewis Y antigen on synovial fluid granulocytes of patients with arthritic joint diseases. Rheumatology (Oxford, England) 40, 1033-1037.
47. Polekhina, G., Giddings, K. S., Tweten, R. K., and Parker, M. W. (2005) Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin. Proc. Natl. Acad. Sci. U.S.A. 102, 600-605.
48. Humphrey, W., Dalke, A., and Schulten, K. (1996) VMD: visual molecular dynamics. J. Mol. Graphics 14, 33-38, 27-38.