Mobilization of protein kinase C in macrophages induced by Listeria monocytogenes affects its internalization and escape from the phagosome

Infection and Immunity

Volumn 70, Issue 8, 2002, Pages 4650-4660

  Wadsworth, Sandra J ^a   Goldfine, Howard ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; CALCIUM CHANNEL BLOCKING AGENT; PROTEIN KINASE C; PROTEIN KINASE C BETA;

ANIMAL CELL; ARTICLE; BACTERIAL VIRULENCE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL TRANSPORT; CELL VACUOLE; CONTROLLED STUDY; CULTURE MEDIUM; INTERNALIZATION; LISTERIA MONOCYTOGENES; MACROPHAGE; NONHUMAN; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TISSUE CULTURE;

ACETOPHENONES; ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; BENZOPYRANS; BIOLOGICAL TRANSPORT; CALCIUM CHANNEL BLOCKERS; CELL LINE; ENDOSOMES; ENZYME INHIBITORS; HEAT-SHOCK PROTEINS; HEMOLYSIN PROTEINS; IMIDAZOLES; ISOENZYMES; LISTERIA MONOCYTOGENES; MACROPHAGES; MICE; PHAGOCYTOSIS; PHAGOSOMES; PHOSPHATIDYLINOSITOL DIACYLGLYCEROL-LYASE; PHOSPHOLIPASE C; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; PYRONES; VACUOLES;

EID: 0036073612     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.8.4650-4660.2002     Document Type: Article

References (35)

1. Phagocytosed live Listeria monocytogenes influences rab5 regulated in vitro phagosome-endosome fusion
2. Differential expression of Listeria monocytogenes virulence genes in mammalian host cells
3. The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway
4. Listeria monocytogenes mutants lacking phosphatidylinositol-specific phospholipase C are avirulent
5. Dual roles of plcA in Listeria monocytogenes pathogenesis
6. Lysosomal enzyme trafficking between phagosomes, endosomes, and lysosomes in J774 macrophages-enrichment of cathepsin H in early endosomes
7. In vitro fusion of endosomes following receptor-mediated endocytosis
8. Macrophage phagocytosis: Use of fluorescence microscopy to distinguish between extracellular and intracellular bacteria
9. Inhibition of glycosidases by aldonolactones of corresponding configuration
10. Purification and characterization of an extracellular 29-kilodalton phospholipase C from Listeria monocytogenes
11. The nonspecific phospholipase C of Listeria monocytogenes: Activity on phospholipids in Triton X-100 mixed micelles and in biological membranes
12. Activation of host phospholipases C and D in macrophages after infection with Listeria monocytogenes
13. Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro
14. Rottlerin, a novel protein kinase inhibitor
15. Characterization of Listeria monocytogenes pathogenesis in a strain expressing perfringolysin O in place of listeriolysin O
16. Five Listeria monocytogenes genes preferentially expressed in infected mammalian cells: plcA, purH, purD, pyrE and an arginine ABC transporter gene, arpJ
17. Rottlerin, a PKC isozyme-selective inhibitor, affects signaling events and cytokine production in human monocytes
18. Fluid phase and mannose receptormediated uptake of horseradish peroxidase in mouse bone marrow-derived macrophages. Biochemical and ultrastructural study
19. Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells
20. Protein kinase C induced calcium influx and sustained enhancement of ciliary beating by extracellular ATP
21. Structural features of the GTP-binding defective Rab5 mutants required for their inhibitory activity on endocytosis
22. Cytolysin-mediated translocation (CMT): A functional equivalent of type III secretion in Grampositive bacteria
23. Identification of phosphatidylinositol-specific phospholipase C activity in Listeria monocytogenes: A novel type of virulence factor
24. Expression of listeriolysin O and ActA by intracellular and extracellular Listeria monocytogenes
25. Role of hemolysin for the intracellular growth of Listeria monocytogenes
26. New insights into the regulation of protein kinase C and novel phorbol ester receptors
27. The listerial exotoxins listeriolysin and phosphatidylinositol-specific phospholipase C synergize to elicit endothelial cell phosphoinositide metabolism
28. Listeriolysin is a potent inducer of the phosphatidylinositol response and lipid mediator generation in human endothelial cells
29. Role of Listeria monocytogenes exotoxins listeriolysin and phosphatidylinositol-specific phospholipase C in activation of human neutrophils
30. The two distinct phospholipases C of Listeria monocytogenes have overlapping roles in escape from a vacuole and cell-to-cell spread
31. Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cδ tyrosine phosphorylation
32. Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
33. Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite Listeria monocytogenes
34. 2+ uptake in rat and chick cultured myoblasts
35. Listeria monocytogenes phospholipase C-dependent calcium signaling modulates bacterial entry into J774 macrophage-like cells