Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 9, 2010, Pages 4341-4346

  Farrand, Allison J ^a   LaChapelle, Stephanie ^a   Hotze, Eileen M ^a   Johnson, Arthur E ^b,c   Tweten, Rodney K ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Hemolysin; Intermedilysin; Pore; Sterol; Toxin

Indexed keywords

BACTERIAL PROTEIN; CHOLESTEROL; CHOLESTEROL DEPENDENT CYTOLYSIN; CLOSTRIDIUM PERFRINGENS TOXIN; CYTOLYSIN; LEUCINE; PNEUMOLYSIN; STREPTOLYSIN O; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CYTOLYSIS; HEMOLYSIS; HUMAN; HUMAN CELL; MEMBRANE; MEMBRANE STRUCTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; SURFACE PROPERTY;

BACTERIAL TOXINS; BINDING SITES; BLOTTING, WESTERN; CHOLESTEROL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLOW CYTOMETRY; GRAM-POSITIVE BACTERIA; HEMOLYSIN PROTEINS; HEMOLYSIS; HUMANS; LEUCINE; MEMBRANE LIPIDS; SURFACE PLASMON RESONANCE; THREONINE;

EUKARYOTA; PROKARYOTA;

EID: 77749292162     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0911581107     Document Type: Article

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