Noncryogenic synthesis of functionalized 2-methoxypyridines by halogen-magnesium exchange using lithium dibutyl(isopropyl)magnesate(1-) and lithium chloride

Synthesis

Volumn 44, Issue 5, 2012, Pages 735-746

  Struk, Łukasz ^a   Sośnicki, Jacek G ^a  

^a WEST POMERANIAN UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

lithium; magnesium; organometallic reagents; pyridines

Indexed keywords

FUNCTIONALIZED; LITHIUM CHLORIDE; NON-CRYOGENIC CONDITIONS; ORGANOMETALLIC REAGENTS; REACTION MEDIUM;

CHLORINE COMPOUNDS; MAGNESIUM; ORGANOMETALLICS; PYRIDINE;

LITHIUM;

(6 METHOXYPYRIDIN 2 YL)(PHENYL)METHANOL; (6 METHOXYPYRIDIN 3 YL)(DIPHENYL)METHANOL; (6 METHOXYPYRIDIN 3 YL)(PHENYL)METHANOL; 1 (6 METHOXYPYRIDIN 3 YL)CYCLOHEXANOL; 1 (6 METHOXYPYRIDIN 3 YL)PROP 2 EN 1 OL; 2 (6 METHOXYPYRIDIN 3 YL)PROPAN 2 OL; 2 ALLYL 6 METHOXYPYRIDINE; 2 METHOXY 5 (PHENYLSULFANYL)PYRIDINE; 2 METHOXY 5 (TRIMETHYLSILYL)PYRIDINE; 2 METHOXY 6 (PHENYLSULFANYL)PYRIDINE; 2 METHOXY 6 (TRIMETHYLSILYL)PYRIDINE; 2 METHOXYPYRIDINE DERIVATIVE; 2,6 DIMETHOXYPYRIDINE; 5 (DIPHENYLPHOSPHINO) 2 METHOXYPYRIDINE; 5 ALLYL 2 METHOXYPYRIDINE; 5 CHLORO 2 METHOXYPYRIDINE; 5 IODO 2 METHOXYPYRIDINE; 6 METHOXY N,N DIMETHYLNICOTINAMIDE; 6 METHOXYPYRIDINE 2 CARBALDEHYDE; 6 METHOXYPYRIDINE 3 CARBALDEHYDE; [(6 METHOXYPYRIDIN 3 YL)METHYL]DIMETHYLAMINE; HALOGEN; LITHIUM CHLORIDE; LITHIUM DERIVATIVE; LITHIUM DIBUTYL(ISOPROPYL)MAGNESATE; MAGNESIUM; N ETHYL 6 METHOXYPYRIDINE 2 CARBOTHIOAMIDE; N ETHYL 6 METHOXYPYRIDINE 3 CARBOTHIOAMIDE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CROSS COUPLING REACTION; ELECTROPHILICITY; HALOGENATION; NUCLEOPHILICITY; PROCESS OPTIMIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; ROOM TEMPERATURE; SYNTHESIS;

EID: 84857456694     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0031-1289687     Document Type: Article

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