A convenient stereoselective synthesis of trans -4a,5,8,8a-tetrahydro-2 h -isoquinolin-1-ones via trans 3-allylation of 4-allyl-3,4-dihydropyridine-2- thiones and RCM as key steps

Synlett

Volumn , Issue 8, 2010, Pages 1209-1214

  Sośnicki, Jacek G ^a   Struk, Łukasz ^a  

^a WEST POMERANIAN UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

(Thio)lactams; 4a,5,8,8a tetrahydro 2 H isoquinolin 1 ones; N acyliminum cation; RCM; Stereoselective trans alkylation

Indexed keywords

3,4 DIALLYLDIHYDRO 1H PYRIDINE 2 THIONE DERIVATIVE; 4 ALLYL 3,4 DIHYDROPYRIDINE 2 THIONE DERIVATIVE; 4A,5,8,8A TETRAHYDRO 2H ISOQUINOLIN 1 ONE; ISOQUINOLINE DERIVATIVE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ALLYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CIS TRANS ISOMERISM; CYCLIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; RING CLOSING METATHESIS; STEREOCHEMISTRY;

EID: 77952038389     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0029-1219792     Document Type: Article

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