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Volumn 43, Issue 3, 2012, Pages 284-289

Simvastatin improves morphological and functional recovery of sciatic nerve injury in Wistar rats

Author keywords

Immunomodulation; Nervous regeneration; Sciatic nerve; Simvastatin

Indexed keywords

SIMVASTATIN;

EID: 84857371918     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/j.injury.2011.05.036     Document Type: Article
Times cited : (49)

References (51)
  • 3
    • 67651174743 scopus 로고    scopus 로고
    • Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury
    • B. Li, A. Mahmood, D. Lu, H. Wu, Y. Xiong, and C. Qu Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury Neurosurgery 65 2009 179 185
    • (2009) Neurosurgery , vol.65 , pp. 179-185
    • Li, B.1    Mahmood, A.2    Lu, D.3    Wu, H.4    Xiong, Y.5    Qu, C.6
  • 4
    • 34848915855 scopus 로고    scopus 로고
    • Discontinuation of statin therapy and clinical outcome after ischemic stroke
    • DOI 10.1161/STROKEAHA.107.487017, PII 0000767020071000000007
    • F. Colivicchi, A. Bassi, M. Santini, and C. Caltagirone Discontinuation of statin therapy and clinical outcome after ischemic stroke Stroke 38 2007 2652 2657 (Pubitemid 47493999)
    • (2007) Stroke , vol.38 , Issue.10 , pp. 2652-2657
    • Colivicchi, F.1    Bassi, A.2    Santini, M.3    Caltagirone, C.4
  • 6
    • 67651158798 scopus 로고    scopus 로고
    • Behavioral and quantitative mitochondrial proteome analyses of the effects of simvastatin: Implications for models of neural degeneration
    • S. Pienaar, T. Scharllet, S. Hattingh, and W.M.U. Daniels Behavioral and quantitative mitochondrial proteome analyses of the effects of simvastatin: implications for models of neural degeneration J Neural Transm 116 2009 791 806
    • (2009) J Neural Transm , vol.116 , pp. 791-806
    • Pienaar, S.1    Scharllet, T.2    Hattingh, S.3    Daniels, W.M.U.4
  • 7
    • 36349022129 scopus 로고    scopus 로고
    • The effects of simvastatin on functional recovery of rat reperfused sciatic nerve
    • M.R. Gholami, F. Abolhassani, P. Pasbakhsh, M. Akbari, and A. Sobhani The effects of simvastatin on functional recovery of rat reperfused sciatic nerve Pak J Biol Sci 10 2008 4256 4260
    • (2008) Pak J Biol Sci , vol.10 , pp. 4256-4260
    • Gholami, M.R.1    Abolhassani, F.2    Pasbakhsh, P.3    Akbari, M.4    Sobhani, A.5
  • 9
    • 33947684873 scopus 로고    scopus 로고
    • Simvastatin promotes neurite outgrowth in the presence of inhibitory molecules found in central nervous system injury
    • DOI 10.1089/neu.2006.23.1366
    • E. Holmberg, T. Nordstrom, M. Gross, B. Kluge, S.X. Zhang, and S. Doolen Simvastatin promotes neurite outgrowth in the presence of inhibitory molecules found in central nervous system injury J Neurotrauma 23 2006 1366 1378 (Pubitemid 46489622)
    • (2006) Journal of Neurotrauma , vol.23 , Issue.9 , pp. 1366-1378
    • Holmberg, E.1    Nordstrom, T.2    Gross, M.3    Kluge, B.4    Zhang, S.-X.5    Doolen, S.6
  • 10
    • 58149218510 scopus 로고    scopus 로고
    • Simvastatin impairs humoral and cell-mediated immunity in mice by inhibiting lymphocyte homing, T-cell activation and antigen cross-presentation
    • C. Ulivieri, D. Fanigliulo, D. Benati, F.L. Pasini, and C.T. Baldari Simvastatin impairs humoral and cell-mediated immunity in mice by inhibiting lymphocyte homing, T-cell activation and antigen cross-presentation Eur J Immunol 38 2008 2832 2844
    • (2008) Eur J Immunol , vol.38 , pp. 2832-2844
    • Ulivieri, C.1    Fanigliulo, D.2    Benati, D.3    Pasini, F.L.4    Baldari, C.T.5
  • 12
    • 36248934262 scopus 로고    scopus 로고
    • Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury
    • DOI 10.1523/JNEUROSCI.3027-07.2007
    • A. Boivin, I. Pineau, B. Barrette, M. Filali, N. Vallires, and S. Rivest Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury J Neurosci 27 2007 12565 12576 (Pubitemid 350127805)
    • (2007) Journal of Neuroscience , vol.27 , Issue.46 , pp. 12565-12576
    • Boivin, A.1    Pineau, I.2    Barrette, B.3    Filali, M.4    Vallieres, N.5    Rivest, S.6    Lacroix, S.7
  • 13
    • 41349104454 scopus 로고    scopus 로고
    • + T cell subsets that develop following mouse facial nerve axotomy
    • DOI 10.1016/j.bbi.2007.10.006, PII S0889159107002619
    • J. Xin, D.A. Wainwright, C.J. Serpe, V.M. Sanders, and K.J. Jones Phenotype of CD4+ T cell subsets that develop following mouse facial nerve axotomy Brain Behav Immun 22 2008 528 537 (Pubitemid 351451827)
    • (2008) Brain, Behavior, and Immunity , vol.22 , Issue.4 , pp. 528-537
    • Xin, J.1    Wainwright, D.A.2    Serpe, C.J.3    Sanders, V.M.4    Jones, K.J.5
  • 14
    • 16844365105 scopus 로고    scopus 로고
    • Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1α and interleukin-1β Wallerian degeneration
    • DOI 10.1093/brain/awh407
    • F.E. Perrin, S. Lacroix, M. Avilés-Trigueros, and S. David Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration Brain 128 2005 854 866 (Pubitemid 40516922)
    • (2005) Brain , vol.128 , Issue.4 , pp. 854-866
    • Perrin, F.E.1    Lacroix, S.2    Aviles-Trieueros, M.3    David, S.4
  • 15
    • 2342551487 scopus 로고    scopus 로고
    • Blocking of up-regulated ICAM-1 does not prevent macrophage infiltration during Wallerian degeneration of peripheral nerve
    • DOI 10.1016/j.expneurol.2004.02.004, PII S0014488604000573
    • A.M. Avellino, A.T. Dailey, J.M. Harlan, S.R. Sharar, R.K. Winn, and L.D. McNutt Blocking of up-regulated ICAM-1 does not prevent macrophage infiltration during Wallerian degeneration of peripheral nerve Exp Neurol 187 2004 430 444 (Pubitemid 38610289)
    • (2004) Experimental Neurology , vol.187 , Issue.2 , pp. 430-444
    • Avellino, A.M.1    Dailey, A.T.2    Harlan, J.M.3    Sharar, S.R.4    Winn, R.K.5    McNutt, L.D.6    Kliot, M.7
  • 16
    • 49049121017 scopus 로고    scopus 로고
    • Effect of betamethasone on the degree of macrophage recruitment and nerve growth factor receptor p75 immunoreaction during recovery of the sciatic nerve after injury: An experimental study in rats
    • A. Al-Bishri, S. Forsgren, Y. Al-Thobaiti, B. Sunzel, and T. Rosenquist Effect of betamethasone on the degree of macrophage recruitment and nerve growth factor receptor p75 immunoreaction during recovery of the sciatic nerve after injury: an experimental study in rats Br J Oral Maxillofac Surg 46 2008 455 459
    • (2008) Br J Oral Maxillofac Surg , vol.46 , pp. 455-459
    • Al-Bishri, A.1    Forsgren, S.2    Al-Thobaiti, Y.3    Sunzel, B.4    Rosenquist, T.5
  • 17
    • 39749162291 scopus 로고    scopus 로고
    • + cells into early lesions of rat traumatic brain injury
    • DOI 10.1007/s00401-007-0301-y
    • Z. Zhang, U. Fauser, and H.J. Schluesener Dexamethasone suppresses infiltration of RhoA+ cells into early lesions of rat traumatic brain injury Acta Neuropathol 115 2008 335 343 (Pubitemid 351292115)
    • (2008) Acta Neuropathologica , vol.115 , Issue.3 , pp. 335-343
    • Zhang, Z.1    Fauser, U.2    Schluesener, H.J.3
  • 18
  • 19
    • 58149250276 scopus 로고    scopus 로고
    • Statins alter neutrophil migration by modulating cellular Rho activity - A potential mechanism for statins-mediated pleotropic effects?
    • B.M. Maher, T.N. Dhonnchu, J.P. Burke, A. Soo, A.E. Wood, and R.W. Watson Statins alter neutrophil migration by modulating cellular Rho activity - a potential mechanism for statins-mediated pleotropic effects? J Leukoc Biol 85 2009 186 193
    • (2009) J Leukoc Biol , vol.85 , pp. 186-193
    • Maher, B.M.1    Dhonnchu, T.N.2    Burke, J.P.3    Soo, A.4    Wood, A.E.5    Watson, R.W.6
  • 20
    • 45549102525 scopus 로고    scopus 로고
    • Simvastatin Inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes
    • X. Zhang, J. Jin, X. Peng, V.S. Ramgolam, and S. Markovic-Plese Simvastatin Inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORC in CD4+ lymphocytes J Immunol 180 2008 6988 6996
    • (2008) J Immunol , vol.180 , pp. 6988-6996
    • Zhang, X.1    Jin, J.2    Peng, X.3    Ramgolam, V.S.4    Markovic-Plese, S.5
  • 21
    • 62549158729 scopus 로고    scopus 로고
    • Statins immunomodulatory potential against Th17 cell-mediated autoimmune response
    • X. Zhang, and S. Markovic-Plese Statins immunomodulatory potential against Th17 cell-mediated autoimmune response Immunol Res 41 2008 165 174
    • (2008) Immunol Res , vol.41 , pp. 165-174
    • Zhang, X.1    Markovic-Plese, S.2
  • 24
    • 0019938340 scopus 로고
    • An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks
    • DOI 10.1016/0014-4886(82)90234-5
    • L. De Medinaceli, W.J. Freed, and R.J. Wyatt An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks Exp Neurol 77 1982 634 643 (Pubitemid 12011176)
    • (1982) Experimental Neurology , vol.77 , Issue.3 , pp. 634-643
    • De Medinaceli, L.1    Freed, W.J.2    Wyatt, R.J.3
  • 25
    • 0024498021 scopus 로고
    • Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat
    • J.R. Bain, S.E. Mackinnon, and D.A. Hunter Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat Plast Reconstr Surg 83 1989 129 138
    • (1989) Plast Reconstr Surg , vol.83 , pp. 129-138
    • Bain, J.R.1    MacKinnon, S.E.2    Hunter, D.A.3
  • 26
  • 27
    • 60549113364 scopus 로고    scopus 로고
    • Simvastatin treatment induces morphology alterations and apoptosis in murine cochlear neuronal cells
    • D.S. Park, H.S. So, J.H. Lee, H.Y. Park, Y.J. Lee, and J.H. Cho Simvastatin treatment induces morphology alterations and apoptosis in murine cochlear neuronal cells Acta Otolaryngol 129 2009 166 174
    • (2009) Acta Otolaryngol , vol.129 , pp. 166-174
    • Park, D.S.1    So, H.S.2    Lee, J.H.3    Park, H.Y.4    Lee, Y.J.5    Cho, J.H.6
  • 28
    • 33748745943 scopus 로고    scopus 로고
    • Suppressive effect of simvastatin on interferon-β-induced expression of CC chemokine ligand 5 in microglia
    • DOI 10.1016/j.neulet.2006.08.044, PII S0304394006008652
    • K. Nakamichi, M. Saiki, H. Kitani, Y. Kuboyama, K. Morimoto, and M. Takayama-Ito Suppressive effect of simvastatin on interferon-beta-induced expression of CC chemokine ligand 5 in microglia Neurosci Lett 407 2006 205 210 (Pubitemid 44402874)
    • (2006) Neuroscience Letters , vol.407 , Issue.3 , pp. 205-210
    • Nakamichi, K.1    Saiki, M.2    Kitani, H.3    Kuboyama, Y.4    Morimoto, K.5    Takayama-Ito, M.6    Kurane, I.7
  • 30
    • 34547098112 scopus 로고    scopus 로고
    • Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury
    • DOI 10.1089/neu.2007.0288
    • D. Lu, C. Qu, A. Goussev, H. Jiang, C. Lu, and T. Schallert Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury J Neurotrauma 24 2007 1132 1146 (Pubitemid 47106287)
    • (2007) Journal of Neurotrauma , vol.24 , Issue.7 , pp. 1132-1146
    • Lu, D.1    Qu, C.2    Goussev, A.3    Jiang, H.4    Lu, C.5    Schallert, T.6    Mahmood, A.7    Chen, J.8    Li, Y.9    Chopp, M.10
  • 31
    • 0036969452 scopus 로고    scopus 로고
    • The processing and presentation of endogenous and exogenous antigen by Schwann cells in vitro
    • DOI 10.1007/s000180200018
    • O. Lilje The processing and presentation of endogenous and exogenous antigen by Schwann cells in vitro Cell Mol Life Sci 59 2002 2191 2198 (Pubitemid 36140292)
    • (2002) Cellular and Molecular Life Sciences , vol.59 , Issue.12 , pp. 2191-2198
    • Lilje, O.1
  • 32
    • 33750024981 scopus 로고    scopus 로고
    • Necrotic neuronal cells induce inflammatory Schwann cell activation via TLR2 and TLR3: Implication in Wallerian degeneration
    • DOI 10.1016/j.bbrc.2006.09.108, PII S0006291X06021619
    • H. Lee, E.K. Jo, S.Y. Choi, S.B. Oh, K. Park, and J.S. Kim Necrotic neuronal cells induce inflammatory Schwann cell activation via TLR2 and TLR3: implication in Wallerian degeneration Biochem Biophys Res Commun 350 2006 742 747 (Pubitemid 44566388)
    • (2006) Biochemical and Biophysical Research Communications , vol.350 , Issue.3 , pp. 742-747
    • Lee, H.1    Jo, E.-K.2    Choi, S.-Y.3    Oh, S.B.4    Park, K.5    Soo Kim, J.6    Lee, S.J.7
  • 33
    • 0035194478 scopus 로고    scopus 로고
    • Differential recruitment of CD8+ macrophages during Wallerian degeneration in the peripheral and central nervous system
    • S. Jander, F. Lausberg, and G. Stoll Differential recruitment of CD8+ macrophages during Wallerian degeneration in the peripheral and central nervous system Brain Pathol 11 2001 27 38
    • (2001) Brain Pathol , vol.11 , pp. 27-38
    • Jander, S.1    Lausberg, F.2    Stoll, G.3
  • 34
    • 33748530684 scopus 로고    scopus 로고
    • Nature of signals that initiate the immune response during Wallerian degeneration of peripheral nerves
    • DOI 10.1016/j.expneurol.2006.05.024, PII S0014488606003219
    • S. Karanth, G. Yang, J. Yeh, and P.M. Richardson Nature of signals that initiate the immune response during Wallerian degeneration of peripheral nerves Exp Neurol 202 2006 161 166 (Pubitemid 44362990)
    • (2006) Experimental Neurology , vol.202 , Issue.1 , pp. 161-166
    • Karanth, S.1    Yang, G.2    Yeh, J.3    Richardson, P.M.4
  • 35
    • 0034597059 scopus 로고    scopus 로고
    • The chemokine receptor CCR2 is involved in macrophage recruitment to the injured peripheral nervous system
    • H. Siebert, A. Sachse, W.A. Kuziel, N. Maeda, and W. Brück The chemokine receptor CCR2 is involved in macrophage recruitment to the injured peripheral nervous system J Neuroimmunol 110 2000 177 185
    • (2000) J Neuroimmunol , vol.110 , pp. 177-185
    • Siebert, H.1    Sachse, A.2    Kuziel, W.A.3    Maeda, N.4    Brück, W.5
  • 37
    • 15444368304 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo
    • DOI 10.1161/01.CIR.0000158484.18024.1F
    • K.H. Han, J. Ryu, K.H. Hong, J. Ko, Y.K. Pak, and J.B. Kim HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant Protein-1-mediated monocyte recruitment in vivo Circulation 111 2005 1439 1447 (Pubitemid 40396811)
    • (2005) Circulation , vol.111 , Issue.11 , pp. 1439-1447
    • Ki, H.H.1    Ryu, J.2    Kyung, H.H.3    Ko, J.4    Youngmi, K.P.5    Kim, J.-B.6    Seong, W.P.7    Jae, J.K.8
  • 38
    • 38649124898 scopus 로고    scopus 로고
    • Simvastatin exerts its anti-inflammatory effect in hypercholesterolaemic patients by decreasing the serum levels of monocyte chemoattractant protein-1
    • DOI 10.1016/j.ijcard.2006.12.059, PII S0167527307003737
    • L.S. Rallidis, E.S. Hamodraka, K. Fountoulaki, G. Moustogiannis, M.G. Zolindaki, and D.T. Kremastinos Simvastatin exerts its anti-inflammatory effect in hypercholesterolaemic patients by decreasing the serum levels of monocyte chemoattractant protein-1 Int J Cardiol 124 2008 271 272 (Pubitemid 351173361)
    • (2008) International Journal of Cardiology , vol.124 , Issue.2 , pp. 271-272
    • Rallidis, L.S.1    Hamodraka, E.S.2    Fountoulaki, K.3    Moustogiannis, G.4    Zolindaki, M.G.5    Kremastinos, D.T.6
  • 39
    • 62049083748 scopus 로고    scopus 로고
    • Simvastatin reduces secondary brain injury caused by cortical contusion in rats: Possible involvement of TLR4/NF-kappaB pathway
    • G. Chen, S. Zhang, J. Shi, J. Ai, M. Qi, and C. Hang Simvastatin reduces secondary brain injury caused by cortical contusion in rats: possible involvement of TLR4/NF-kappaB pathway Exp Neurol 216 2009 398 406
    • (2009) Exp Neurol , vol.216 , pp. 398-406
    • Chen, G.1    Zhang, S.2    Shi, J.3    Ai, J.4    Qi, M.5    Hang, C.6
  • 41
    • 39049162829 scopus 로고    scopus 로고
    • Decreased peripheral nerve damage after ischemia-reperfusion injury in mice lacking TNF-alpha
    • DOI 10.1016/j.jns.2007.10.004, PII S0022510X07007034
    • Y. Wang, N. Kawamura, J.D. Schmelzer, A.M. Schmeichel, and P.A. Low Decreased peripheral nerve damage after ischemia-reperfusion injury in mice lacking TNF-alpha J Neurol Sci 267 2008 107 111 (Pubitemid 351248913)
    • (2008) Journal of the Neurological Sciences , vol.267 , Issue.1-2 , pp. 107-111
    • Wang, Y.1    Kawamura, N.2    Schmelzer, J.D.3    Schmeichel, A.M.4    Low, P.A.5
  • 43
    • 41149103459 scopus 로고    scopus 로고
    • Activated polymorphonuclear cells promote injury and excitability of dorsal root ganglia neurons
    • S.K. Shaw, S.A. Owolabi, J. Bagley, N. Morin, E. Cheng, and B.W. LeBlanc Activated polymorphonuclear cells promote injury and excitability of dorsal root ganglia neurons Exp Neurol 210 2009 286 294
    • (2009) Exp Neurol , vol.210 , pp. 286-294
    • Shaw, S.K.1    Owolabi, S.A.2    Bagley, J.3    Morin, N.4    Cheng, E.5    Leblanc, B.W.6
  • 44
    • 33847631663 scopus 로고    scopus 로고
    • The role of T helper cells in neuroprotection and regeneration
    • DOI 10.1016/j.jneuroim.2006.11.019, PII S0165572806004723, Inflammation, Neurodegeneration and Neuroprotection in the Central Nervous System
    • S. Hendrix, and R. Nitsch The role of T helper cells in neuroprotection and regeneration J Neuroimmunol 184 2007 100 112 (Pubitemid 46365994)
    • (2007) Journal of Neuroimmunology , vol.184 , Issue.1-2 , pp. 100-112
    • Hendrix, S.1    Nitsch, R.2
  • 45
    • 0026742832 scopus 로고
    • Facial nerve transection causes expansion of myelin autoreactive T cells in regional lymph nodes and T cell homing to the facial nucleus
    • T. Olsson, P. Diener, A. Ljungdahl, B. Höjeberg, P.H. van der Meide, and K. Kristensson Facial nerve transection causes expansion of myelin autoreactive T cells in regional lymph nodes and T cell homing to the facial nucleus Autoimmunity 13 1992 117 126
    • (1992) Autoimmunity , vol.13 , pp. 117-126
    • Olsson, T.1    Diener, P.2    Ljungdahl, A.3    Höjeberg, B.4    Van Der Meide, P.H.5    Kristensson, K.6
  • 47
    • 49749111057 scopus 로고    scopus 로고
    • Simvastatin alters human endothelial cell adhesion molecule expression and inhibits leukocyte adhesion under flow
    • K.A. Eccles, H. Sowden, K.E. Porter, S.M. Parkin, S. Homer-Vanniasinkam, and A.M. Graham Simvastatin alters human endothelial cell adhesion molecule expression and inhibits leukocyte adhesion under flow Atherosclerosis 200 2008 69 79
    • (2008) Atherosclerosis , vol.200 , pp. 69-79
    • Eccles, K.A.1    Sowden, H.2    Porter, K.E.3    Parkin, S.M.4    Homer-Vanniasinkam, S.5    Graham, A.M.6
  • 48
    • 0030814892 scopus 로고    scopus 로고
    • Mevalonate-dependent inhibition of transendothelial migration and chemotaxis of human peripheral blood neutrophils by pravastatin
    • S. Dunzendorfer, D. Rothbucher, P. Schratzberger, N. Reinisch, C.M. Kähler, and C.J. Wiedermann Mevalonate-dependent inhibition of transendothelial migration and chemotaxis of human peripheral blood neutrophils by pravastatin Circ Res 81 1997 963 969 (Pubitemid 27514945)
    • (1997) Circulation Research , vol.81 , Issue.6 , pp. 963-969
    • Dunzendorfer, S.1    Rothbucher, D.2    Schratzberger, P.3    Reinisch, N.4    Kahler, C.M.5    Wiedermann, C.J.6
  • 49
    • 34547652325 scopus 로고    scopus 로고
    • Why is Wallerian degeneration in the CNS so slow?
    • DOI 10.1146/annurev.neuro.30.051606.094354
    • M.E. Vargas, and B.A. Barres Why is Wallerian degeneration in the CNS so slow? Annu Rev Neurosci 30 2007 153 179 (Pubitemid 47218754)
    • (2007) Annual Review of Neuroscience , vol.30 , pp. 153-179
    • Vargas, M.E.1    Barres, B.A.2
  • 50
    • 61549129995 scopus 로고    scopus 로고
    • Interactions between Schwann cells and macrophages in injury and inherited demyelinating disease
    • R. Martini, S. Fischer, R. López-Vales, and S. David Interactions between Schwann cells and macrophages in injury and inherited demyelinating disease Glia 56 2008 1566 1577
    • (2008) Glia , vol.56 , pp. 1566-1577
    • Martini, R.1    Fischer, S.2    López-Vales, R.3    David, S.4
  • 51
    • 39149103724 scopus 로고    scopus 로고
    • Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury
    • DOI 10.1089/neu.2007.0369
    • H. Wu, D. Lu, H. Jiang, Y. Xiong, C. Qu, and B. Li Simvastatin-mediated upregulation of VEGF and BDNF, Activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury J Neurotrauma 25 2008 130 139 (Pubitemid 351252578)
    • (2008) Journal of Neurotrauma , vol.25 , Issue.2 , pp. 130-139
    • Wu, H.1    Lu, D.2    Jiang, H.3    Xiong, Y.4    Qu, C.5    Li, B.6    Mahmood, A.7    Zhou, D.8    Chopp, M.9


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