HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo

Circulation

Volumn 111, Issue 11, 2005, Pages 1439-1447

  Ki, Hoon Han ^a   Ryu, Jewon ^a,b   Kyung, Hee Hong ^a   Ko, Jesang ^a   Youngmi, Kim Pak ^a   Kim, Jae Bum ^b   Seong, Wook Park ^a   Jae, Joong Kim ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Atherosclerosis; Cells; Receptors; Statins

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; CHEMOKINE RECEPTOR CCR2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MONOCYTE CHEMOTACTIC PROTEIN 1; RECEPTOR BLOCKING AGENT; ROSIGLITAZONE; SIMVASTATIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA WALL; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INFLAMMATORY CELL; MALE; MONOCYTE; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANILIDES; ANIMALS; AORTA; CELLS, CULTURED; CHEMOKINE CCL2; CHEMOTAXIS, LEUKOCYTE; DEPRESSION, CHEMICAL; DIET, ATHEROGENIC; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERCHOLESTEROLEMIA; MALE; MEVALONIC ACID; MICE; MICE, INBRED C57BL; MONOCYTES; POLYISOPRENYL PHOSPHATES; PPAR GAMMA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CHEMOKINE; RNA, MESSENGER; SIMVASTATIN; THIAZOLIDINEDIONES;

EID: 15444368304     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000158484.18024.1F     Document Type: Article

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