Simvastatin alters human endothelial cell adhesion molecule expression and inhibits leukocyte adhesion under flow

Atherosclerosis

Volumn 200, Issue 1, 2008, Pages 69-79

  Eccles, Kirstie A ^a   Sowden, Heather ^b   Porter, Karen E ^c   Parkin, Sue M ^a   Homer Vanniasinkam, Shervanthi ^d   Graham, Anne M ^a  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c UNIVERSITY OF LEEDS   (United Kingdom)

^d LEEDS GENERAL INFIRMARY   (United Kingdom)

Author keywords

Cell adhesion molecules; Endothelial cells; In vitro laminar flow; Inflammation; Simvastatin

Indexed keywords

CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HISTAMINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPID; MEVALONIC ACID; PADGEM PROTEIN; SIMVASTATIN; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; INFLAMMATION; LEUKOCYTE ADHERENCE INHIBITION; LEUKOCYTE ROLLING; MORBIDITY; MORTALITY; NEUTROPHIL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS;

CELL ADHESION; CELLS, CULTURED; E-SELECTIN; ENDOTHELIAL CELLS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LEUKOCYTE ROLLING; NEUTROPHILS; P-SELECTIN; RHEOLOGY; SIMVASTATIN; UMBILICAL VEINS;

EID: 49749111057     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2007.12.018     Document Type: Article

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