메뉴 건너뛰기




Volumn 20, Issue 1, 2012, Pages 62-67

Apigenin sensitizes Huh-7 human hepatocellular carcinoma cells to TRAIL-induced apoptosis

Author keywords

Apoptosis; Bcl 2 family; Caspase family; Combination; Huh 7; TRAIL

Indexed keywords

APIGENIN; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 8; CASPASE 9; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 84857187752     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2012.20.1.062     Document Type: Article
Times cited : (19)

References (37)
  • 1
    • 33847328289 scopus 로고    scopus 로고
    • The Bcl-2 apoptotic switch in cancer development and therapy
    • Adams, J. M. and Cory, S. (2007) The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene. 26, 1324-1337.
    • (2007) Oncogene , vol.26 , pp. 1324-1337
    • Adams, J.M.1    Cory, S.2
  • 2
    • 61449198651 scopus 로고    scopus 로고
    • Therapeutic effi cacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer
    • Andrzejewski, T., Deeb, D., Gao, X., Danyluk, A., Arbab, A. S., Dulchavsky, S. A. and Gautam, S. C. (2008) Therapeutic effi cacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer. Oncol. Res. 17, 257-267.
    • (2008) Oncol. Res. , vol.17 , pp. 257-267
    • Andrzejewski, T.1    Deeb, D.2    Gao, X.3    Danyluk, A.4    Arbab, A.S.5    Dulchavsky, S.A.6    Gautam, S.C.7
  • 3
    • 0037507288 scopus 로고    scopus 로고
    • Adenoviral gene transfer of tumor necrosis factor-related apoptosis-inducing ligand overcomes an impaired response of hepatoma cells but causes severe apoptosis in primary human hepatocytes
    • Armeanu, S., Lauer, U. M., Smirnow, I., Schenk, M., Weiss, T. S., Gregor, M. and Bitzer, M. (2003) Adenoviral gene transfer of tumor necrosis factor-related apoptosis-inducing ligand overcomes an impaired response of hepatoma cells but causes severe apoptosis in primary human hepatocytes. Cancer Res. 63, 2369-2372.
    • (2003) Cancer Res , vol.63 , pp. 2369-2372
    • Armeanu, S.1    Lauer, U.M.2    Smirnow, I.3    Schenk, M.4    Weiss, T.S.5    Gregor, M.6    Bitzer, M.7
  • 6
    • 0031057115 scopus 로고    scopus 로고
    • Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant fl avonoid
    • Birt, D. F., Mitchell, D., Gold, B., Pour, P. and Pinch, H. C. (1997) Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant fl avonoid. Anticancer. Res. 17, 85-91.
    • (1997) Anticancer. Res. , vol.17 , pp. 85-91
    • Birt, D.F.1    Mitchell, D.2    Gold, B.3    Pour, P.4    Pinch, H.C.5
  • 7
    • 33646828739 scopus 로고    scopus 로고
    • Antiproliferative effect of apigenin and its apoptotic induction in human Hep G2 cells
    • Chiang, L. C., Ng, L. T., Lin, I. C., Kuo, P. L. and Lin, C. C. (2006) Antiproliferative effect of apigenin and its apoptotic induction in human Hep G2 cells. Cancer Lett. 237, 207-214.
    • (2006) Cancer Lett , vol.237 , pp. 207-214
    • Chiang, L.C.1    Ng, L.T.2    Lin, I.C.3    Kuo, P.L.4    Lin, C.C.5
  • 8
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen, G. M. (1997) Caspases: the executioners of apoptosis. Biochem. J. 326, 1-16.
    • (1997) Biochem. J , vol.326 , pp. 1-16
    • Cohen, G.M.1
  • 9
    • 4444294803 scopus 로고    scopus 로고
    • Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-κB through suppression of IκBα phosphorylation
    • Deeb, D., Jiang, H., Gao, X., Hafner, M. S, Wong, H., Divine, G., Chapman, R. A., Dulchavsky, S. A. and Gautam, S. C. (2004) Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-κB through suppression of IκBα phosphorylation. Mol. Cancer Ther. 3, 803-812.
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 803-812
    • Deeb, D.1    Jiang, H.2    Gao, X.3    Hafner, M.S.4    Wong, H.5    Divine, G.6    Chapman, R.A.7    Dulchavsky, S.A.8    Gautam, S.C.9
  • 10
    • 0035866396 scopus 로고    scopus 로고
    • Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression
    • Eggert, A., Grotzer, M. A., Zuzak, T. J., Wiewrodt, B. R., Ho, R., Ikegaki, N. and Brodeur, G. M. (2001) Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression. Cancer Res. 61, 1314-1319.
    • (2001) Cancer Res , vol.61 , pp. 1314-1319
    • Eggert, A.1    Grotzer, M.A.2    Zuzak, T.J.3    Wiewrodt, B.R.4    Ho, R.5    Ikegaki, N.6    Brodeur, G.M.7
  • 11
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross, A., McDonnell, J. M. and Korsmeyer, S. J. (1999) BCL-2 family members and the mitochondria in apoptosis. Genes. Dev. 13, 1899-1911.
    • (1999) Genes. Dev. , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 12
    • 0035812747 scopus 로고    scopus 로고
    • Selective growth-inhibitory, cell-cycle deregulatory and apoptotic response of apigenin in normal versus human prostate carcinoma cells
    • Gupta, S., Afaq, F. and Mukhtar, H. (2001) Selective growth-inhibitory, cell-cycle deregulatory and apoptotic response of apigenin in normal versus human prostate carcinoma cells. Biochem. Biophys. Res. Commun. 287, 914-920.
    • (2001) Biochem. Biophys. Res. Commun. , vol.287 , pp. 914-920
    • Gupta, S.1    Afaq, F.2    Mukhtar, H.3
  • 14
    • 34250357227 scopus 로고    scopus 로고
    • Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1
    • Higashitsuji, H., Higashitsuji, H., Masuda, T., Liu, Y., Itoh, K. and Fujita, J. (2007) Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1. J. Biol. Chem. 282, 13716-13725.
    • (2007) J. Biol. Chem. , vol.282 , pp. 13716-13725
    • Higashitsuji, H.1    Higashitsuji, H.2    Masuda, T.3    Liu, Y.4    Itoh, K.5    Fujita, J.6
  • 16
    • 77956642345 scopus 로고    scopus 로고
    • Combining naturally occurring polyphenols with TNF-related apoptosis-inducing ligand: A promising approach to kill resistant cancer cells?
    • Jacquemin, G., Shirley, S. and Micheau, O. (2010) Combining naturally occurring polyphenols with TNF-related apoptosis-inducing ligand: a promising approach to kill resistant cancer cells? Cell Mol. Life Sci. 67, 3115-3130.
    • (2010) Cell Mol. Life Sci. , vol.67 , pp. 3115-3130
    • Jacquemin, G.1    Shirley, S.2    Micheau, O.3
  • 17
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: A link between cancer genetics and chemotherapy
    • Johnstone, R. W., Ruefli, A. A. and Lowe, S. W. (2002) Apoptosis: a link between cancer genetics and chemotherapy. Cell. 108, 153-164.
    • (2002) Cell , vol.108 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 18
    • 27744609173 scopus 로고    scopus 로고
    • Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5)
    • Jung, E. M., Lim, J. H., Lee, T. J., Park, J. W., Choi, K. S. and Kwon, T. K. (2005) Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5). Carcinogenesis. 26, 1905-1913.
    • (2005) Carcinogenesis , vol.26 , pp. 1905-1913
    • Jung, E.M.1    Lim, J.H.2    Lee, T.J.3    Park, J.W.4    Choi, K.S.5    Kwon, T.K.6
  • 19
  • 20
    • 33947368690 scopus 로고    scopus 로고
    • TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specifi c apoptosis within a therapeutic window
    • Koschny, R., Ganten, T. M., Sykora, J., Haas, T. L., Sprick, M. R., Kolb, A., Stremmel, W. and Walczak, H. (2007) TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specifi c apoptosis within a therapeutic window. Hepatology. 45, 649-658.
    • (2007) Hepatology , vol.45 , pp. 649-658
    • Koschny, R.1    Ganten, T.M.2    Sykora, J.3    Haas, T.L.4    Sprick, M.R.5    Kolb, A.6    Stremmel, W.7    Walczak, H.8
  • 21
    • 41049112098 scopus 로고    scopus 로고
    • TRAIL and cancer therapy
    • Kruyt, F. A. (2008) TRAIL and cancer therapy. Cancer Lett. 263, 14-25.
    • (2008) Cancer Lett , vol.263 , pp. 14-25
    • Kruyt, F.A.1
  • 23
    • 0035970721 scopus 로고    scopus 로고
    • Nuclear and mitochondrial apoptotic pathways of p53
    • Moll, U. M. and Zaika, A. (2001) Nuclear and mitochondrial apoptotic pathways of p53. FEBS. Lett. 493, 65-69.
    • (2001) FEBS. Lett. , vol.493 , pp. 65-69
    • Moll, U.M.1    Zaika, A.2
  • 24
    • 0034596514 scopus 로고    scopus 로고
    • Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)
    • Nitsch, R., Bechmann, I., Deisz, R. A., Haas, D., Lehmann, T. N., Wendling, U., and Zipp, F. (2000) Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL). Lancet. 356, 827-828.
    • (2000) Lancet , vol.356 , pp. 827-828
    • Nitsch, R.1    Bechmann, I.2    Deisz, R.A.3    Haas, D.4    Lehmann, T.N.5    Wendling, U.6    Zipp, F.7
  • 25
    • 0033584823 scopus 로고    scopus 로고
    • Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity
    • Roth, W., Isenmann, S., Naumann, U., Kügler, S., Bähr, M., Dichgans, J., Ashkenazi, A. and Weller, M. (1999) Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity. Biochem. Biophys. Res. Commun. 265, 479-483.
    • (1999) Biochem. Biophys. Res. Commun. , vol.265 , pp. 479-483
    • Roth, W.1    Isenmann, S.2    Naumann, U.3    Kügler, S.4    Bähr, M.5    Dichgans, J.6    Ashkenazi, A.7    Weller, M.8
  • 26
    • 56249131797 scopus 로고    scopus 로고
    • The fl avonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin
    • Siegelin, M. D., Reuss, D. E., Habel, A., Herold-Mende, C. and von Deimling, A. (2008) The fl avonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin. Mol. Cancer Ther. 7, 3566-3574.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3566-3574
    • Siegelin, M.D.1    Reuss, D.E.2    Habel, A.3    Herold-Mende, C.4    von Deimling, A.5
  • 27
    • 0033582526 scopus 로고    scopus 로고
    • Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis
    • Sun, X. M., MacFarlane, M., Zhuang, J., Wolf, B. B., Green, D. R. and Cohen, G. M. (1999) Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J. Biol. Chem. 274, 5053-5060.
    • (1999) J. Biol. Chem. , vol.274 , pp. 5053-5060
    • Sun, X.M.1    Macfarlane, M.2    Zhuang, J.3    Wolf, B.B.4    Green, D.R.5    Cohen, G.M.6
  • 28
    • 14844288360 scopus 로고    scopus 로고
    • Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: Paving the road to patient-tailored therapy
    • Van Geelen, C. M., de Vries, E. G. and de Jong, S. (2004) Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy. Drug Resist. Updat. 7, 345-358.
    • (2004) Drug Resist. Updat. , vol.7 , pp. 345-358
    • van Geelen, C.M.1    de Vries, E.G.2    de Jong, S.3
  • 30
    • 0033933197 scopus 로고    scopus 로고
    • Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines
    • Wang, W., Heideman, L., Chung, C. S., Pelling, J. C., Koehler, K. J. and Birt, D. F. (2000) Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines. Mol. Carcinog. 28, 102-110.
    • (2000) Mol. Carcinog. , vol.28 , pp. 102-110
    • Wang, W.1    Heideman, L.2    Chung, C.S.3    Pelling, J.C.4    Koehler, K.J.5    Birt, D.F.6
  • 31
    • 1042289764 scopus 로고    scopus 로고
    • Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neuoverexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway
    • Way, T. D., Kao, M. C. and Lin, J. K. (2003) Apigenin induces apoptosis through proteasomal degradation of HER2/neu in HER2/neuoverexpressing breast cancer cells via the phosphatidylinositol 3-kinase/Akt-dependent pathway. J. Biol. Chem. 279, 4479-4489.
    • (2003) J. Biol. Chem. , vol.279 , pp. 4479-4489
    • Way, T.D.1    Kao, M.C.2    Lin, J.K.3
  • 32
    • 0025176844 scopus 로고
    • Inhibitory effect of apigenin, a plant fl avonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice
    • Wei, H., Tye, L., Bresnick, E. and Birt, D. F. (1990) Inhibitory effect of apigenin, a plant fl avonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice. Cancer Res. 50, 499-502.
    • (1990) Cancer Res , vol.50 , pp. 499-502
    • Wei, H.1    Tye, L.2    Bresnick, E.3    Birt, D.F.4
  • 33
    • 0033575255 scopus 로고    scopus 로고
    • Suicidal tendencies: Apoptotic cell death by caspase family proteinases
    • Wolf, B. B. and Green, D. R. (1999) Suicidal tendencies: apoptotic cell death by caspase family proteinases. J. Biol. Chem. 274, 20049-20052.
    • (1999) J. Biol. Chem. , vol.274 , pp. 20049-20052
    • Wolf, B.B.1    Green, D.R.2
  • 36
    • 14644437742 scopus 로고    scopus 로고
    • Mechanisms of resistance to TRAILinduced apoptosis in cancer
    • Zhang, L. and Fang, B. (2005) Mechanisms of resistance to TRAILinduced apoptosis in cancer. Cancer Gene Ther. 12, 228-237.
    • (2005) Cancer Gene Ther , vol.12 , pp. 228-237
    • Zhang, L.1    Fang, B.2
  • 37
    • 57749097095 scopus 로고    scopus 로고
    • TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5
    • Zhang, Y. and Zhang, B. (2008) TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5. Mol. Cancer Res. 6, 1861-1871.
    • (2008) Mol. Cancer Res. , vol.6 , pp. 1861-1871
    • Zhang, Y.1    Zhang, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.