Structural analysis and modeling of a synthetic interleukin-2 mimetic and its interleukin-2Rβ2 receptor

Journal of Biological Chemistry

Volumn 278, Issue 25, 2003, Pages 22868-22876

  Rose, Thierry ^a   Moreau, Jean Louis ^a   Eckenberg, Ralph ^a   Thèze, Jacques ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; CHEMICAL BONDS; CONFORMATIONS; CRYSTAL STRUCTURE; CYTOLOGY; DIMERIZATION; HYDROPHOBICITY; TUMORS;

CIRCULAR DICHROISM;

PROTEINS;

AMINO ACID; INTERLEUKIN 2 DERIVATIVE; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR BETA2; PEPTIDE; PEPTIDE P1 30; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CENTRIFUGATION; CIRCULAR DICHROISM; COMPLEX FORMATION; CRYSTAL STRUCTURE; CYTOPLASM; DIMERIZATION; HYDROPHOBICITY; MODEL; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; ROTATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; HUMANS; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; KINETICS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, INTERLEUKIN; RECOMBINANT PROTEINS; T-LYMPHOCYTES; TRANSFECTION;

ANIMALIA;

EID: 0038265184     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M301757200     Document Type: Article

References (43)

1. Smith, K. A. (1988) Science 240, 1169-1176
2. Taniguchi, T., Matsui, H., Fujita, T., Takaoka, C., Kashima, N., Yoshimoto, R., and Hamuro, J. (1983) Nature 302, 305-310
3. Robb, R. J., Kutny, R. M., Panico, M., Morris, H. R., and Chowdhry, V. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 6486-6490
4. MacKay, D. (1992) Science 257, 410-413
5. Thèze, J., Alzari, P. M., and Bertoglio, J. (1996) Immunol. Today 10, 481-486
6. Minami, Y., Kono, T., Miyazaki, T., and Taniguchi, T. (1993) Annu. Rev. Immunol. 11, 245-267
7. Taniguchi, T., and Minami, Y. (1993) Cell 73, 5-8
8. Uchiyama, T., Broder, S., and Waldmann, T. (1981) J. Immunol. 126, 1293-1297
9. Leonard, W. J., Depper, J. M., Crabtree, G. R., Rudikoff, S., Punphery, J., Robb, R. J., Kronke, M., Svetlik, P. B., Peffer, N. J., Waldmann, T. A., and Greene, W. C. (1984) Nature 311, 626-631
10. Teshigawara, K., Wang, H. M., Kato, K., and Smith, K. A. (1987) J. Exp. Med. 165, 223-238
11. Hatakeyama, M., Tsudo, M., Minamoto, S., Kono, T., Doi, T., Miyata, T., Miyasaka, M., and Taniguchi, T. (1989) Science 244, 551-556
12. Tsudo, M., Kitamura, F., and Miyasaka, M. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 1982-1986
13. Takeshita, T., Asao, H., Ohtani, K., Ishii, N., Kumaki, S., Tanaka, N., Munakata, H., Nakamura, M., and Sugamura, K. (1992) Science 257, 379-382
14. Thèze, J. (1994) Eur. Cytokine Network 5, 353-368
15. Giri, J. G., Kumaki, S., Ahdieh, M., Friend, D. J., Loomis, A., Shanebeck, K., DuBose, R., Cosman, D., Park, L. S., and Anderson, D. M. (1995) EMBO. J. 14, 3654-3663
16. Bamborough, P., Hedgecock, C. J., and Richards, W. G. (1994) Structure 2, 839-851
17. Sauvé, K., Nachman, M., Spence, C., Bailon, P., Campbell, E., Tsien, W.-H., Kondas, J. A., Hakimi, J., and Ju, G. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 4636-4640
18. Wang, Z., Zheng, Z., Sun, L., and Liu, X. (1995) Eur. J. Immunol. 25, 1212-1216
19. Voss, S. D., Leary, T. P., Sondel, P. M., and Robb, R. J. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2428-2432
20. Buchli, P., and Ciardelli, T. (1993) Arch. Biochim. Biophys. 307, 411-415
21. Eckenberg, R., Xu, D., Moreau, J. L., Bossus, M., Mazie, J. C., Tartar, A., Liu, X. Y., Alzari, P. M., Bertoglio, J., and Thèze, J. (1997) Cytokine 9, 488-498
22. Eckenberg, R., Rose, T., Moreau, J.-L., Weil, R., Gesbert, F., Dubois, S., Tello, D., Bossus, M., Gras, H., Tartar, A., Bertoglio, J., Chouaib, S., Goldberg, M., Jacques, Y., Alzari, P. M., and Thèze, J. (2000) J. Exp. Med. 191, 529-540
23. Livnah, O., Stura, E. A., Middleton, S. A., Johnson, D. L., Jolliffe, L. K., and Wilson, I. A. (1999) Science 283, 987-990
24. De Vos, A. M., Ultsch, M., and Kossiakoff, A. A. (1992) Science 255, 306-312
25. Pitton, C., Rebollo, A., Snick, J. V., Thèze, J., and Garcia, A. (1993) Cytokine 5, 362-371
26. Manavalan, P., and Johnson, W., Jr. (1987) Anal. Biochem. 167, 76-85
27. Cheetham, J. C., Smith, D. M., Aoki, K. H., Stevenson, J. L., Hoeffel, T. J., Syed, R. S., Egrie, J., and Harvey, T. S. (1998) Nat. Struct. Biol. 5, 861-866
28. Banner, D. W., Kokkinidis, M., and Tsernoglou, D. (1987) J. Mol. Biol. 196, 657-675
29. Berman, H. M., Westbrook, J., Feng, Z., Gilliland, G., Bhat, T. N., Weissig, H., Shindyalov, I. N., and Bourne, P. E. (2000) Nucleic Acids Res. 28, 235-242
30. Thompson, J. D., Gibson, T. J., Plewniak, F., Jeanmougin, F., and Higgins, D. G. (1997) Nucleic Acids Res., 25, 4876-4882
31. Sali, A., and Blundell, T. L. (1993) J. Mol. Biol. 234, 779-815
32. Syed, R. S., Reid, S. W., Li, C., Cheetham, J. C., Aoki, K. H., Liu, B., Zhan, H., Osslund, T. D., Chirino, A. J., Zhang, J., Finer-Moore, J., Elliott, S., Sitney, K., Katz, B. A., Matthews, D. J., Wendoloski, J. J., Egrie, J., and Stroud, R. M. (1998) Nature 395, 511-516
33. Laskowski, R. A., Moss, D. S., and Thornton, J. M. (1993) J. Mol. Biol., 231, 1049-1067
34. Eisenberg, D., Luthy, R., and Bowie, J. U. (1997) Methods Enzymol. 277, 396-404
35. Hooft, R. W. W., Vriend, G., Sander, C., and Abola, E. E. (1996) Nature 381, 272-272
36. Baker, B. M., and Murphy, K. P. (1998) Methods Enzymol. 295, 294-315
37. D'Aquino, J. A., Gomez, J., Hilser, V. J., Lee, K. H., Amzel, L. M., and Freire, E. (1996) Proteins 25, 143-156
38. Lee, K. H., Xie, D., Freire, E., and Amzel, L. M. (1994) Proteins 20, 68-84
39. Wrighton, N. C., Farrell, F. X., Chang, R., Kashyap, A. K., Barbone, F. P., Mulcahy, L. S., Johnson, D. L., Barrett, R. W., Jolliffe, L. K., and Dower, W. J. (1996) Science 273, 458-464
40. Remy, I., Wilson, I. A., and Michnick, S. W. (1999) Science 283, 990-993
41. Wilson, I. A., and Jolliffe, L. K. (1999) Curr. Opin. Struct. Biol. 9, 696-704
42. David, D., Bani, L., Moreau, J.-L., Demaison, C., Sun, K., Salvucci, O., Nakarai, T., de Montalembert, M., Chouaïb, S., Joussemet, M., Ritz, J., and Thèze, J. (1998) Blood 91, 165-172
43. Baluna, R., Rizo, J., Gordon, B. E., Ghetie, V., and Vitetta, E. S. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3957-3962