Enhanced hippocampal long-term potentiation and spatial learning in aged 11β-hydroxysteroid dehydrogenase type 1 knock-out mice

Journal of Neuroscience

Volumn 27, Issue 39, 2007, Pages 10487-10496

  Yau, Joyce L W ^a   McNair, Kara M ^b   Noble, June ^a   Brownstein, David ^a   Hibberd, Carina ^a   Morton, Nik ^a   Mullins, John J ^a   Morris, Richard G M ^c   Cobb, Stuart ^b   Seckl, Jonathan R ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Ageing; Glucocorticoids; Hippocampus; LTP; Memory; Neurogenesis

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; 11BETA HYDROXYSTEROID DEHYDROGENASE 1; CORTICOSTERONE; GLUCOCORTICOID; GLUCOSE; INSULIN; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; C57BL 6 MOUSE; COGNITION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DENTATE GYRUS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HIPPOCAMPUS; INSULIN METABOLISM; KNOCKOUT MOUSE; LEARNING; LONG TERM POTENTIATION; MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPATIAL MEMORY; WORKING MEMORY;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; AGE FACTORS; AGING; ANIMALS; COGNITION; HIPPOCAMPUS; LONG-TERM POTENTIATION; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 34848923074     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2190-07.2007     Document Type: Article

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