MiRNA genes constitute new targets for microsatellite instability in colorectal cancer

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  El Murr, Nizar ^a,b   Abidi, Zoulira ^a,b   Wanherdrick, Kristell ^a,b   Svrcek, Magali ^a,b,c   Gaub, Marie Pierre ^d   Fléjou, Jean François ^a,b,c   Hamelin, Richard ^a,b   Duval, Alex ^a,b   Lesuffleur, Thécla ^a,b  

^a CENTRE DE RECHERCHE SAINT ANTOINE   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c HÔPITAL SAINT ANTOINE   (France)

^d INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DINUCLEOTIDE REPEAT; HSA MIR 1273C GENE; HSA MIR 1303 GENE; HSA MIR 567 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAXIMUM LIKELIHOOD METHOD; MICRORNA GENE; MICROSATELLITE INSTABILITY; MONONCLEOTIDE REPEAT; MUTATIONAL ANALYSIS; NUCLEOTIDE REPEAT; POLYMERASE CHAIN REACTION; RNA GENE; SEQUENCE ANALYSIS; TUMOR GROWTH; CELL TRANSFORMATION; COLORECTAL TUMOR; GENETICS; MUTATION RATE; NUCLEOTIDE SEQUENCE; STATISTICAL MODEL;

MICRORNA;

CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; HUMANS; LIKELIHOOD FUNCTIONS; MICRORNAS; MICROSATELLITE INSTABILITY; MUTATION RATE;

EID: 84856896776     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031862     Document Type: Article

References (35)

1. Filipowicz W, Bhattacharyya SN, Sonenberg N, (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9: 102-114.
2. Melo SA, Esteller M, (2011) Dysregulation of microRNAs in cancer: Playing with fire. FEBS Lett in press.
3. Esquela-Kerscher A, Slack FJ, (2006) Oncomirs- microRNAs with a role in cancer. Nat Rev Cancer 6: 259-269.
4. Olena AF, Patton JG, (2010) Genomic organization of microRNAs. J Cell Physiol 222: 540-545.
5. Winter J, Jung S, Keller S, Gregory RI, Diederichs S, (2009) Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol 11: 228-234.
6. Griffiths-Jones S, Saini HK, van Dongen S, Enright AJ, (2008) miRBase: tools for microRNA genomics. Nucleic Acids Res 36: D154-158.
7. Zeng Y, Cullen BR, (2005) Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. J Biol Chem 280: 27595-27603.
8. Zeng Y, Yi R, Cullen BR, (2005) Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. Embo J 24: 138-148.
9. Zhang X, Zeng Y, (2010) The terminal loop region controls microRNA processing by Drosha and Dicer. Nucleic Acids Res 38: 7689-7697.
10. Han J, Lee Y, Yeom KH, Nam JW, Heo I, et al. (2006) Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125: 887-901.
11. Wu M, Jolicoeur N, Li Z, Zhang L, Fortin Y, et al. (2008) Genetic variations of microRNAs in human cancer and their effects on the expression of miRNAs. Carcinogenesis 29: 1710-1716.
12. Ryan BM, Robles AI, Harris CC, (2010) Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer 10: 389-402.
13. Calin GA, Croce CM, (2006) MicroRNAs and chromosomal abnormalities in cancer cells. Oncogene 25: 6202-6210.
14. Breving K, Esquela-Kerscher A, (2009) The complexities of microRNA regulation: mirandering around the rules. Int J Biochem Cell Biol 42: 1316-1329.
15. Krol J, Loedige I, Filipowicz W, (2010) The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11: 597-610.
16. Toyota M, Suzuki H, Sasaki Y, Maruyama R, Imai K, et al. (2008) Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res 68: 4123-4132.
17. Diosdado B, van de Wiel MA, Terhaar Sive Droste JS, Mongera S, Postma C, et al. (2009) MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. Br J Cancer 101: 707-714.
18. Boland CR, Goel A, (2010) Microsatellite instability in colorectal cancer. Gastroenterology 138: 2073-2087.
19. Duval A, Hamelin R, (2002) Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability. Cancer Res 62: 2447-2454.
20. Woerner SM, Benner A, Sutter C, Schiller M, Yuan YP, et al. (2003) Pathogenesis of DNA repair-deficient cancers: a statistical meta-analysis of putative Real Common Target genes. Oncogene 22: 2226-2235.
21. Giannini G, Ristori E, Cerignoli F, Rinaldi C, Zani M, et al. (2002) Human MRE11 is inactivated in mismatch repair-deficient cancers. EMBO Rep 3: 248-254.
22. Dorard C, de Thonel A, Collura A, Marisa L, Svrcek M, et al. (2011) Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis. Nat Med 17: 1283-1289.
23. Duan S, Mi S, Zhang W, Dolan ME, (2009) Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genes. RNA Biol 6: 412-425.
24. Duval A, Rolland S, Compoint A, Tubacher E, Iacopetta B, et al. (2001) Evolution of instability at coding and non-coding repeat sequences in human MSI-H colorectal cancers. Hum Mol Genet 10: 513-518.
25. Melo SA, Ropero S, Moutinho C, Aaltonen LA, Yamamoto H, et al. (2009) A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet 41: 365-370.
26. Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, et al. (2010) A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell 18: 303-315.
27. Garre P, Perez-Segura P, Diaz-Rubio E, Caldes T, de la Hoya M, (2010) Reassessing the TARBP2 mutation rate in hereditary nonpolyposis colorectal cancer. Nat Genet 42: 817-818.
28. Kim MS, Oh JE, Kim YR, Park SW, Kang MR, et al. (2010) Somatic mutations and losses of expression of microRNA regulation-related genes AGO2 and TNRC6A in gastric and colorectal cancers. J Pathol 221: 139-146.
29. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, et al. (1998) A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58: 5248-5257.
30. Perucho M, (1999) Correspondence re: C.R. Boland et al., A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 58: 5248-5257, 1998. Cancer Res 59: 249-256.
31. Duan R, Pak C, Jin P, (2007) Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum Mol Genet 16: 1124-1131.
32. Hu Z, Chen J, Tian T, Zhou X, Gu H, et al. (2008) Genetic variants of miRNA sequences and non-small cell lung cancer survival. J Clin Invest 118: 2600-2608.
33. Jazdzewski K, Liyanarachchi S, Swierniak M, Pachucki J, Ringel MD, et al. (2009) Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer. Proc Natl Acad Sci U S A 106: 1502-1505.
34. Trujillo RD, Yue SB, Tang Y, O'Gorman WE, Chen CZ, (2010) The potential functions of primary microRNAs in target recognition and repression. Embo J 29: 3272-3285.
35. Buhard O, Cattaneo F, Wong YF, Yim SF, Friedman E, et al. (2006) Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors. J Clin Oncol 24: 241-251.