Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis

Nature Medicine

Volumn 17, Issue 10, 2011, Pages 1283-1289

  Dorard, Coralie ^a,b   De Thonel, Aurélie ^a,c   Collura, Ada ^a,b   Marisa, Laetitia ^d   Svrcek, Magali ^a,b,e   Lagrange, Anaïs ^a,b   Jego, Gaetan ^a,c   Wanherdrick, Kristell ^a,b   Joly, Anne Laure ^a,c   Buhard, Olivier ^a,b   Gobbo, Jessica ^a,c   Penard Lacronique, Virginie ^f   Zouali, Habib ^g   Tubacher, Emmanuel ^g   Kirzin, Sylvain ^a   Selves, Janick ^a   Milano, Gérard ^h   Etienne Grimaldi, Marie Christine ^h   Bengrine Lefevre, Leila ^e   Louvet, Christophe ^e   Tournigand, Christophe ^e   Lefvre, Jérémie H ^b,e   Parc, Yann ^b,e   Tiret, Emmanuel ^b,e   Fléjou, Jean François ^a,b,e   Gaub, Marie Pierre ^a   Garrido, Carmen ^a,c,i   Duval, Alex ^a,b   more..

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITÉ DE BOURGOGNE   (France)

^d Ligue Nationale Contre le Cancer   (France)

^e HÔPITAL SAINT ANTOINE   (France)

^f INSTITUT GUSTAVE ROUSSY   (France)

^g FONDATION JEAN DAUSSET CEPH   (France)

^h CENTRE ANTOINE LACASSAGNE   (France)

ⁱ DIJON UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHAPERONE; FLUOROURACIL; HEAT SHOCK PROTEIN 110; MESSENGER RNA; MUTANT PROTEIN; OXALIPLATIN;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CHEMOSENSITIVITY; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE FREE SURVIVAL; DNA REPAIR; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TREATMENT OUTCOME;

ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA PRIMERS; FLUORESCENT ANTIBODY TECHNIQUE; FLUOROURACIL; HSP110 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPRECIPITATION; MICROSATELLITE INSTABILITY; MUTATION; ORGANOPLATINUM COMPOUNDS; PLASMIDS; PROGNOSIS; REAL-TIME POLYMERASE CHAIN REACTION; REGRESSION ANALYSIS; TRANSFECTION;

EID: 80053987011     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2457     Document Type: Article

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