MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins

Biochemical Journal

Volumn 442, Issue 2, 2012, Pages 413-422

  Tachi, Nobuyuki ^a   Hashimoto, Yuichi ^a   Matsuoka, Masaaki ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease (AD); Amyloid precursor protein (APP); Modifier of cell adhesion (MOCA); Neuronal death; Presenilin (PS)

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; MODIFIER OF CELL ADHESION PROTEIN; PRESENILIN; PRESENILIN 1; PRESENILIN 2; PROTEIN CDC42; RAC1 PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL ADHESION; CONTROLLED STUDY; GENE MUTATION; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BASE SEQUENCE; CARRIER PROTEINS; CELL DEATH; DNA PRIMERS; GENE KNOCKDOWN TECHNIQUES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; HYBRID CELLS; MAP KINASE KINASE KINASE 5; MICE; MUTANT PROTEINS; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NEUROPEPTIDES; PRESENILINS; RAC GTP-BINDING PROTEINS; RATS; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84856891043     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20100993     Document Type: Article

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