Ruthenium-arene complexes of curcumin: X-ray and density functional theory structure, synthesis, and spectroscopic characterization, in vitro antitumor activity, and DNA docking studies of (p-cymene)Ru(curcuminato)chloro

Journal of Medicinal Chemistry

Volumn 55, Issue 3, 2012, Pages 1072-1081

  Caruso, Francesco ^a   Rossi, Miriam ^b   Benson, Aidan ^b   Opazo, Cristian ^b   Freedman, Daniel ^c   Monti, Elena ^d   Gariboldi, Marzia Bruna ^d   Shaulky, Jodi ^e   Marchetti, Fabio ^f   Pettinari, Riccardo ^f   Pettinari, Claudio ^f  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b VASSAR COLLEGE   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

^d UNIVERSITY OF INSUBRIA   (Italy)

^e ACCELRYS INC   (United States)

^f UNIVERSITY OF CAMERINO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHLORINE; CURCUMIN; RUTHENIUM COMPLEX;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN A2780; CELL STRAIN A549; CELL STRAIN HCT116; CELL STRAIN MCF 7; CELL STRAIN U 87; CONTROLLED STUDY; CRYSTAL STRUCTURE; DENSITY FUNCTIONAL THEORY; DRUG DNA BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; IN VITRO STUDY; TUMOR CELL LINE; X RAY ANALYSIS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; CURCUMIN; DNA; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RUTHENIUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84856875441     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm200912j     Document Type: Article

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