-
1
-
-
0037709883
-
Von Hippel-Lindau disease
-
R.R. Lonser von Hippel-Lindau disease Lancet 361 2003 2059 2067
-
(2003)
Lancet
, vol.361
, pp. 2059-2067
-
-
Lonser, R.R.1
-
2
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
A.G. Knudson Jr Mutation and cancer: statistical study of retinoblastoma Proc. Natl. Acad. Sci. U. S. A. 68 1971 820 823
-
(1971)
Proc. Natl. Acad. Sci. U. S. A.
, vol.68
, pp. 820-823
-
-
Knudson, A.G.1
Jr2
-
3
-
-
7844234770
-
Improved detection of germline mutations in the von Hippel-Lindau disease tumor suppressor gene
-
C. Stolle Improved detection of germline mutations in the von Hippel-Lindau disease tumor suppressor gene Hum. Mutat. 12 1998 417 423
-
(1998)
Hum. Mutat.
, vol.12
, pp. 417-423
-
-
Stolle, C.1
-
5
-
-
16144365122
-
Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan
-
B. Zbar Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan Hum. Mutat. 8 1996 348 357
-
(1996)
Hum. Mutat.
, vol.8
, pp. 348-357
-
-
Zbar, B.1
-
6
-
-
2642601107
-
Software and database for the analysis of mutations in the VHL gene
-
C. Beroud Software and database for the analysis of mutations in the VHL gene Nucleic Acids Res. 26 1998 256 258
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 256-258
-
-
Beroud, C.1
-
7
-
-
85012446260
-
Molecular pathology of von Hippel-Lindau disease and the VHL tumour suppressor gene
-
F.M. Richards Molecular pathology of von Hippel-Lindau disease and the VHL tumour suppressor gene Expert Rev. Mol. Med. 1 2001 1 27
-
(2001)
Expert Rev. Mol. Med.
, vol.1
, pp. 1-27
-
-
Richards, F.M.1
-
8
-
-
0034040350
-
Epidemiologic aspects of renal cell cancer
-
J.K. McLaughlin, and L. Lipworth Epidemiologic aspects of renal cell cancer Semin. Oncol. 27 2000 115 123
-
(2000)
Semin. Oncol.
, vol.27
, pp. 115-123
-
-
McLaughlin, J.K.1
Lipworth, L.2
-
9
-
-
0027168746
-
Mapping the Von Hippel-Lindau disease tumour suppressor gene: Identification of germline deletions by pulsed field gel electrophoresis
-
F.M. Richards Mapping the Von Hippel-Lindau disease tumour suppressor gene: identification of germline deletions by pulsed field gel electrophoresis Hum. Mol. Genet. 2 1993 879 882
-
(1993)
Hum. Mol. Genet.
, vol.2
, pp. 879-882
-
-
Richards, F.M.1
-
10
-
-
0032578357
-
PVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation
-
O. Iliopoulos pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation Proc. Natl. Acad. Sci. U. S. A. 95 1998 11661 11666
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 11661-11666
-
-
Iliopoulos, O.1
-
11
-
-
0029926989
-
Expression of the von Hippel-Lindau disease tumour suppressor gene during human embryogenesis
-
F.M. Richards Expression of the von Hippel-Lindau disease tumour suppressor gene during human embryogenesis Hum. Mol. Genet. 5 1996 639 644
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 639-644
-
-
Richards, F.M.1
-
12
-
-
0037223823
-
Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL
-
A. Hergovich Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL Nat. Cell Biol. 5 2003 64 70
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 64-70
-
-
Hergovich, A.1
-
13
-
-
0030847165
-
Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice
-
J.R. Gnarra Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice Proc. Natl. Acad. Sci. U. S. A. 94 1997 9102 9107
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 9102-9107
-
-
Gnarra, J.R.1
-
14
-
-
0035852668
-
Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor
-
V.H. Haase Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor Proc. Natl. Acad. Sci. U. S. A. 98 2001 1583 1588
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 1583-1588
-
-
Haase, V.H.1
-
15
-
-
0141816848
-
Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene
-
W. Ma Hepatic vascular tumors, angiectasis in multiple organs, and impaired spermatogenesis in mice with conditional inactivation of the VHL gene Cancer Res. 63 2003 5320 5328
-
(2003)
Cancer Res.
, vol.63
, pp. 5320-5328
-
-
Ma, W.1
-
16
-
-
1542399554
-
Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice
-
E. Kleymenova Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice Carcinogenesis 25 2004 309 315
-
(2004)
Carcinogenesis
, vol.25
, pp. 309-315
-
-
Kleymenova, E.1
-
17
-
-
0033565672
-
The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity
-
J. Lisztwan The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity Genes Dev. 13 1999 1822 1833
-
(1999)
Genes Dev.
, vol.13
, pp. 1822-1833
-
-
Lisztwan, J.1
-
18
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
P.H. Maxwell The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis Nature 399 1999 271 275
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
-
19
-
-
0036216692
-
HIF-1 and tumor progression: Pathophysiology and therapeutics
-
G.L. Semenza HIF-1 and tumor progression: pathophysiology and therapeutics Trends Mol. Med. 8 Suppl. 4 2002 S62 S67
-
(2002)
Trends Mol. Med.
, vol.8
, Issue.4
-
-
Semenza, G.L.1
-
21
-
-
2342597973
-
Inhibition of HIF2α is sufficient to suppress pVHL-defective tumor growth
-
K. Kondo Inhibition of HIF2α is sufficient to suppress pVHL-defective tumor growth PLoS Biol. 1 2003 E83
-
(2003)
PLoS Biol.
, vol.1
-
-
Kondo, K.1
-
22
-
-
0038383678
-
Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth
-
F.A. Mack Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth Cancer Cell 3 2003 75 88
-
(2003)
Cancer Cell
, vol.3
, pp. 75-88
-
-
MacK, F.A.1
-
23
-
-
0029785838
-
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene
-
J.R. Gnarra Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene Proc. Natl. Acad. Sci. U. S. A. 93 1996 10589 10594
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 10589-10594
-
-
Gnarra, J.R.1
-
24
-
-
0035503345
-
Prognostic impacts of cytogenetic findings in clear cell renal cell carcinoma: Gain of 5q31-qter predicts a distinct clinical phenotype with favorable prognosis
-
B. Gunawan Prognostic impacts of cytogenetic findings in clear cell renal cell carcinoma: gain of 5q31-qter predicts a distinct clinical phenotype with favorable prognosis Cancer Res. 61 2001 7731 7738
-
(2001)
Cancer Res.
, vol.61
, pp. 7731-7738
-
-
Gunawan, B.1
-
25
-
-
0242581718
-
-/- renal cell carcinoma cells
-
-/- renal cell carcinoma cells J. Biol. Chem. 278 2003 44966 44974
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44966-44974
-
-
Gunaratnam, L.1
-
26
-
-
0031964099
-
Transforming growth factor α is a target for the von Hippel-Lindau tumor suppressor
-
B. Knebelmann Transforming growth factor α is a target for the von Hippel-Lindau tumor suppressor Cancer Res. 58 1998 226 231
-
(1998)
Cancer Res.
, vol.58
, pp. 226-231
-
-
Knebelmann, B.1
-
27
-
-
0035852630
-
-/- clear cell renal carcinoma cell proliferation: A possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis
-
-/- clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis Proc. Natl. Acad. Sci. U. S. A. 98 2001 1387 1392
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 1387-1392
-
-
De Paulsen, N.1
-
28
-
-
0036718539
-
Molecular basis of the VHL hereditary cancer syndrome
-
W.G. Kaelin Jr Molecular basis of the VHL hereditary cancer syndrome Nat. Rev. Cancer 2 2002 673 682
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 673-682
-
-
Kaelin, W.G.1
Jr2
-
29
-
-
0032581277
-
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
-
P. Carmeliet Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis Nature 394 1998 485 490
-
(1998)
Nature
, vol.394
, pp. 485-490
-
-
Carmeliet, P.1
-
30
-
-
0034735902
-
The von Hippel-Lindau tumor suppressor gene protects cells from UV-mediated apoptosis
-
A.R. Schoenfeld The von Hippel-Lindau tumor suppressor gene protects cells from UV-mediated apoptosis Oncogene 19 2000 5851 5857
-
(2000)
Oncogene
, vol.19
, pp. 5851-5857
-
-
Schoenfeld, A.R.1
-
31
-
-
0035798604
-
The von Hippel-Lindau gene product inhibits renal cell apoptosis via Bcl-2-dependent pathways
-
P. Devarajan The von Hippel-Lindau gene product inhibits renal cell apoptosis via Bcl-2-dependent pathways J. Biol. Chem. 276 2001 40599 40605
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40599-40605
-
-
Devarajan, P.1
-
32
-
-
2542601328
-
Hypoxia inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target
-
C. Potter, and A.L. Harris Hypoxia inducible carbonic anhydrase IX, marker of tumour hypoxia, survival pathway and therapy target Cell Cycle 3 2004 164 167
-
(2004)
Cell Cycle
, vol.3
, pp. 164-167
-
-
Potter, C.1
Harris, A.L.2
-
33
-
-
0033181324
-
Interleukin-1β and tumor necrosis factor-α stimulate DNA binding of hypoxia-inducible factor-1
-
T. Hellwig-Burgel Interleukin-1β and tumor necrosis factor-α stimulate DNA binding of hypoxia-inducible factor-1 Blood 94 1999 1561 1567
-
(1999)
Blood
, vol.94
, pp. 1561-1567
-
-
Hellwig-Burgel, T.1
-
34
-
-
0035661664
-
HIF-1 expression in healing wounds: HIF-1α induction in primary inflammatory cells by TNF-α
-
J.E. Albina HIF-1 expression in healing wounds: HIF-1α induction in primary inflammatory cells by TNF-α Am. J. Physiol. Cell Physiol. 281 2001 C1971 C1977
-
(2001)
Am. J. Physiol. Cell Physiol.
, vol.281
-
-
Albina, J.E.1
-
35
-
-
0027333425
-
Tumor necrosis factor, other cytokines and disease
-
K.J. Tracey, and A. Cerami Tumor necrosis factor, other cytokines and disease Annu. Rev. Cell Biol. 9 1993 317 343
-
(1993)
Annu. Rev. Cell Biol.
, vol.9
, pp. 317-343
-
-
Tracey, K.J.1
Cerami, A.2
-
36
-
-
0037444823
-
Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor κ B activation
-
Y. Jung Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor κ B activation Biochem. J. 370 2003 1011 1017
-
(2003)
Biochem. J.
, vol.370
, pp. 1011-1017
-
-
Jung, Y.1
-
37
-
-
0037204026
-
Serial analysis of gene expression in renal carcinoma cells reveals VHL-dependent sensitivity to TNFα cytotoxicity
-
M.C. Caldwell Serial analysis of gene expression in renal carcinoma cells reveals VHL-dependent sensitivity to TNFα cytotoxicity Oncogene 21 2002 929 936
-
(2002)
Oncogene
, vol.21
, pp. 929-936
-
-
Caldwell, M.C.1
-
38
-
-
0242694963
-
The von Hippel-Lindau tumor suppressor protein sensitizes renal cell carcinoma cells to tumor necrosis factor-induced cytotoxicity by suppressing the nuclear factor-κB-dependent antiapoptotic pathway
-
H. Qi, and M. Ohh The von Hippel-Lindau tumor suppressor protein sensitizes renal cell carcinoma cells to tumor necrosis factor-induced cytotoxicity by suppressing the nuclear factor-κB-dependent antiapoptotic pathway Cancer Res. 63 2003 7076 7080
-
(2003)
Cancer Res.
, vol.63
, pp. 7076-7080
-
-
Qi, H.1
Ohh, M.2
-
39
-
-
0033600881
-
Direct interaction of the β-domain of VHL tumor suppressor protein with the regulatory domain of atypical PKC isotypes
-
H. Okuda Direct interaction of the β-domain of VHL tumor suppressor protein with the regulatory domain of atypical PKC isotypes Biochem. Biophys. Res. Commun. 263 1999 491 497
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.263
, pp. 491-497
-
-
Okuda, H.1
-
40
-
-
0035941291
-
The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C
-
H. Okuda The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C J. Biol. Chem. 276 2001 43611 43617
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43611-43617
-
-
Okuda, H.1
-
41
-
-
0027402592
-
Molecular aspects of tumor cell invasion and metastasis
-
S. Aznavoorian Molecular aspects of tumor cell invasion and metastasis Cancer 71 1993 1368 1383
-
(1993)
Cancer
, vol.71
, pp. 1368-1383
-
-
Aznavoorian, S.1
-
42
-
-
0032926793
-
Fibronectin and its integrin receptors in cancer
-
E. Ruoslahti Fibronectin and its integrin receptors in cancer Adv. Cancer Res. 76 1999 1 20
-
(1999)
Adv. Cancer Res.
, vol.76
, pp. 1-20
-
-
Ruoslahti, E.1
-
43
-
-
0025214421
-
Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells
-
F.G. Giancotti, and E. Ruoslahti Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells Cell 60 1990 849 859
-
(1990)
Cell
, vol.60
, pp. 849-859
-
-
Giancotti, F.G.1
Ruoslahti, E.2
-
44
-
-
0032085240
-
The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix
-
M. Ohh The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix Mol. Cell 1 1998 959 968
-
(1998)
Mol. Cell
, vol.1
, pp. 959-968
-
-
Ohh, M.1
-
45
-
-
0032211360
-
Von Hippel-Lindau gene-mediated growth suppression and induction of differentiation in renal cell carcinoma cells grown as multicellular tumor spheroids
-
B. Lieubeau-Teillet von Hippel-Lindau gene-mediated growth suppression and induction of differentiation in renal cell carcinoma cells grown as multicellular tumor spheroids Cancer Res. 58 1998 4957 4962
-
(1998)
Cancer Res.
, vol.58
, pp. 4957-4962
-
-
Lieubeau-Teillet, B.1
-
46
-
-
0037093099
-
Role of the von Hippel-Lindau tumor suppressor gene in the formation of β1-integrin fibrillar adhesions
-
M.A. Esteban-Barragan Role of the von Hippel-Lindau tumor suppressor gene in the formation of β1-integrin fibrillar adhesions Cancer Res. 62 2002 2929 2936
-
(2002)
Cancer Res.
, vol.62
, pp. 2929-2936
-
-
Esteban-Barragan, M.A.1
-
47
-
-
1842557655
-
PVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development
-
N.H. Stickle pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development Mol. Cell. Biol. 24 2004 3251 3261
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 3251-3261
-
-
Stickle, N.H.1
-
48
-
-
0031684848
-
Protein kinase C-δ is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation
-
W. Li Protein kinase C-δ is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation Mol. Cell. Biol. 18 1998 5888 5898
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 5888-5898
-
-
Li, W.1
-
49
-
-
0037434790
-
Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity
-
S. Etienne-Manneville, and A. Hall Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity Nature 421 2003 753 756
-
(2003)
Nature
, vol.421
, pp. 753-756
-
-
Etienne-Manneville, S.1
Hall, A.2
-
50
-
-
0036224749
-
The APC gene in colorectal cancer
-
R. Fodde The APC gene in colorectal cancer Eur. J. Cancer 38 2002 867 871
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 867-871
-
-
Fodde, R.1
-
51
-
-
0032795938
-
The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells
-
S. Koochekpour The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells Mol. Cell. Biol. 19 1999 5902 5912
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5902-5912
-
-
Koochekpour, S.1
-
52
-
-
0141828145
-
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL
-
P. Staller Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL Nature 425 2003 307 311
-
(2003)
Nature
, vol.425
, pp. 307-311
-
-
Staller, P.1
-
53
-
-
84867544604
-
Metalloproteinases and their inhibitors in angiogenesis
-
M.A. Lafleur Metalloproteinases and their inhibitors in angiogenesis Expert Rev. Mol. Med. 5 2003 1 39
-
(2003)
Expert Rev. Mol. Med.
, vol.5
, pp. 1-39
-
-
Lafleur, M.A.1
-
54
-
-
0037478437
-
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
-
S. Pennacchietti Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene Cancer Cell 3 2003 347 361
-
(2003)
Cancer Cell
, vol.3
, pp. 347-361
-
-
Pennacchietti, S.1
-
55
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
A. Muller Involvement of chemokine receptors in breast cancer metastasis Nature 410 2001 50 56
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
-
56
-
-
10744219598
-
Regulation of the chemokine receptor CXCR4 by hypoxia
-
T. Schioppa Regulation of the chemokine receptor CXCR4 by hypoxia J. Exp. Med. 198 2003 1391 1402
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1391-1402
-
-
Schioppa, T.1
-
57
-
-
19144371868
-
A genetic register for von Hippel-Lindau disease
-
I.R. Maddock A genetic register for von Hippel-Lindau disease J. Med. Genet. 33 1996 120 127
-
(1996)
J. Med. Genet.
, vol.33
, pp. 120-127
-
-
Maddock, I.R.1
-
58
-
-
0025314788
-
Statistical analysis of the two stage mutation model in von Hippel-Lindau disease, and in sporadic cerebellar haemangioblastoma and renal cell carcinoma
-
E.R. Maher Statistical analysis of the two stage mutation model in von Hippel-Lindau disease, and in sporadic cerebellar haemangioblastoma and renal cell carcinoma J. Med. Genet. 27 1990 311 314
-
(1990)
J. Med. Genet.
, vol.27
, pp. 311-314
-
-
Maher, E.R.1
-
59
-
-
0031837459
-
Haemangioblastoma of the central nervous system in von Hippel-Lindau disease
-
S. Richard Haemangioblastoma of the central nervous system in von Hippel-Lindau disease J. Intern. Med. 243 1998 547 553
-
(1998)
J. Intern. Med.
, vol.243
, pp. 547-553
-
-
Richard, S.1
-
60
-
-
0035903468
-
Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
-
N. Masson Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation EMBO J. 20 2001 5197 5206
-
(2001)
EMBO J.
, vol.20
, pp. 5197-5206
-
-
Masson, N.1
-
61
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
A.C. Epstein C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation Cell 107 2001 43 54
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.1
-
62
-
-
0036469038
-
Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch
-
D. Lando Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch Science 295 2002 858 861
-
(2002)
Science
, vol.295
, pp. 858-861
-
-
Lando, D.1
-
63
-
-
0035887011
-
FIH-1: A novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
-
P.C. Mahon FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity Genes Dev. 15 2001 2675 2686
-
(2001)
Genes Dev.
, vol.15
, pp. 2675-2686
-
-
Mahon, P.C.1
-
64
-
-
0038037735
-
Regulation of angiogenesis by hypoxia: Role of the HIF system
-
C.W. Pugh, and P.J. Ratcliffe Regulation of angiogenesis by hypoxia: role of the HIF system Nat. Med. 9 2003 677 684
-
(2003)
Nat. Med.
, vol.9
, pp. 677-684
-
-
Pugh, C.W.1
Ratcliffe, P.J.2
-
65
-
-
18744375998
-
Regulation and destabilization of HIF-1α by ARD1-mediated acetylation
-
J.W. Jeong Regulation and destabilization of HIF-1α by ARD1-mediated acetylation Cell 111 2002 709 720
-
(2002)
Cell
, vol.111
, pp. 709-720
-
-
Jeong, J.W.1
-
66
-
-
0037016769
-
Jab1 interacts directly with HIF-1α and regulates its stability
-
M.K. Bae Jab1 interacts directly with HIF-1α and regulates its stability J. Biol. Chem. 277 2002 9 12
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9-12
-
-
Bae, M.K.1
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