Depletion of a nucleolar protein activates xenobiotic detoxification genes in Caenorhabditis elegans via Nrf /SKN-1 and p53/CEP-1

Free Radical Biology and Medicine

Volumn 52, Issue 5, 2012, Pages 937-950

  Leung, Chi K ^a   Empinado, Hyacinth ^a   Choe, Keith P ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Ageing; Gene regulation; Ribosome biogenesis; Stress

Indexed keywords

GLUTATHIONE TRANSFERASE; PROTEIN; PROTEIN P53; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; WDR 46 PROTEIN;

5' UNTRANSLATED REGION; ARTICLE; BIOGENESIS; CAENORHABDITIS ELEGANS; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE MUTATION; GENE SILENCING; LIFESPAN; LOSS OF FUNCTION MUTATION; NONHUMAN; NUCLEOLUS; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; RNA INTERFERENCE; RNA PROCESSING;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL NUCLEOLUS; DNA-BINDING PROTEINS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; LIFE EXPECTANCY; METABOLIC DETOXICATION, DRUG; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; RNA, RIBOSOMAL; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; XENOBIOTICS;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 84856752547     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.12.009     Document Type: Article

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