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Volumn 81, Issue 12, 2007, Pages 849-858

Effects of the flavonoids kaempferol and fisetin on thermotolerance, oxidative stress and FoxO transcription factor DAF-16 in the model organism Caenorhabditis elegans

Author keywords

Caenorhabditis elegans; DAF 16; Fisetin; Kaempferol; Lipofuscin accumulation; Stress resistance

Indexed keywords

FISETIN; KAEMPFEROL; LIPOFUSCIN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DAF 16;

EID: 34748829513     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-007-0215-4     Document Type: Article
Times cited : (164)

References (49)
  • 1
    • 33744976074 scopus 로고    scopus 로고
    • C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span
    • Berdichevsky A, Viswanathan M, Horvitz HR, Guarente L (2006) C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span. Cell 125:1165-1177
    • (2006) Cell , vol.125 , pp. 1165-1177
    • Berdichevsky, A.1    Viswanathan, M.2    Horvitz, H.R.3    Guarente, L.4
  • 2
    • 33846206505 scopus 로고    scopus 로고
    • Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans
    • Brown MK, Evans JL, Luo Y (2006) Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans. Pharmacol Biochem Behav 85:620-628
    • (2006) Pharmacol Biochem Behav , vol.85 , pp. 620-628
    • Brown, M.K.1    Evans, J.L.2    Luo, Y.3
  • 3
    • 0037085734 scopus 로고    scopus 로고
    • Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA
    • Bruskov VI, Malakhova LV, Masalimov ZK, Chernikov AV (2002) Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA. Nucleic Acids Res 30:1354-1363
    • (2002) Nucleic Acids Res , vol.30 , pp. 1354-1363
    • Bruskov, V.I.1    Malakhova, L.V.2    Masalimov, Z.K.3    Chernikov, A.V.4
  • 4
    • 0031945918 scopus 로고    scopus 로고
    • Crystal structure of a novel human peroxidase enzyme at 2.0 a resolution
    • Choi HJ, Kang SW, Yang CH, Rhee SG, Ryu SE (1998) Crystal structure of a novel human peroxidase enzyme at 2.0 A resolution. Nat Struct Biol 5:400-406
    • (1998) Nat Struct Biol , vol.5 , pp. 400-406
    • Choi, H.J.1    Kang, S.W.2    Yang, C.H.3    Rhee, S.G.4    Ryu, S.E.5
  • 5
    • 0012974721 scopus 로고    scopus 로고
    • Role of free radicals in alcohol-induced tissue injuriy
    • Taylor and Francis Washington and London
    • Colton C, Zahari S (1997) Role of free radicals in alcohol-induced tissue injuriy. In: Baskin SI, Salem H (eds) Oxidants, antioxidants and free radicals. Taylor and Francis, Washington and London, pp 259-271
    • (1997) Oxidants, Antioxidants and Free Radicals , pp. 259-271
    • Colton, C.1    Zahari, S.2    Baskin, S.I.3    Salem, H.4
  • 6
    • 0025756918 scopus 로고
    • Enzymic mechanisms of superoxide production
    • Cross AR, Jones OT (1991) Enzymic mechanisms of superoxide production. Biochim Biophys Acta 1057:281-298
    • (1991) Biochim Biophys Acta , vol.1057 , pp. 281-298
    • Cross, A.R.1    Jones, O.T.2
  • 7
    • 0031081410 scopus 로고    scopus 로고
    • A proposed refinement of the mitochondrial free radical theory of aging
    • de Grey AD (1997) A proposed refinement of the mitochondrial free radical theory of aging. Bioessays 19:161-166
    • (1997) Bioessays , vol.19 , pp. 161-166
    • De Grey, A.D.1
  • 8
    • 0033968516 scopus 로고    scopus 로고
    • The reductive hotspot hypothesis: An update
    • de Grey AD (2000) The reductive hotspot hypothesis: an update. Arch Biochem Biophys 373:295-301
    • (2000) Arch Biochem Biophys , vol.373 , pp. 295-301
    • De Grey, A.D.1
  • 9
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T, Holbrook NJ (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408:239-247
    • (2000) Nature , vol.408 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 11
    • 33644798225 scopus 로고    scopus 로고
    • Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan
    • Gami MS, Wolkow CA (2006) Studies of Caenorhabditis elegans DAF-2/insulin signaling reveal targets for pharmacological manipulation of lifespan. Aging Cell 5:31-37
    • (2006) Aging Cell , vol.5 , pp. 31-37
    • Gami, M.S.1    Wolkow, C.A.2
  • 12
    • 0036021375 scopus 로고    scopus 로고
    • Genetic analysis of tissue aging in Caenorhabditis elegans: A role for heat-shock factor and bacterial proliferation
    • Garigan D, Hsu AL, Fraser AG, Kamath RS, Ahringer J, Kenyon C (2002) Genetic analysis of tissue aging in Caenorhabditis elegans: a role for heat-shock factor and bacterial proliferation. Genetics 161:1101-1112
    • (2002) Genetics , vol.161 , pp. 1101-1112
    • Garigan, D.1    Hsu, A.L.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Kenyon, C.6
  • 13
    • 23844436700 scopus 로고    scopus 로고
    • In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans
    • Gerstbrein B, Stamatas G, Kollias N, Driscoll M (2005) In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans. Aging Cell 4:127-137
    • (2005) Aging Cell , vol.4 , pp. 127-137
    • Gerstbrein, B.1    Stamatas, G.2    Kollias, N.3    Driscoll, M.4
  • 14
    • 33644797213 scopus 로고    scopus 로고
    • Endocrine targets for pharmacological intervention in aging in Caenorhabditis elegans
    • Gill MS (2006) Endocrine targets for pharmacological intervention in aging in Caenorhabditis elegans. Aging Cell 5:23-30
    • (2006) Aging Cell , vol.5 , pp. 23-30
    • Gill, M.S.1
  • 15
    • 0041326859 scopus 로고    scopus 로고
    • An automated high-throughput assay for survival of the nematode Caenorhabditis elegans
    • Gill MS, Olsen A, Sampayo JN, Lithgow GJ (2003) An automated high-throughput assay for survival of the nematode Caenorhabditis elegans. Free Radic Biol Med 35:558-565
    • (2003) Free Radic Biol Med , vol.35 , pp. 558-565
    • Gill, M.S.1    Olsen, A.2    Sampayo, J.N.3    Lithgow, G.J.4
  • 16
    • 33746344025 scopus 로고    scopus 로고
    • ROS as signalling molecules in T cells-evidence for abnormal redox signalling in the autoimmune disease, rheumatoid arthritis
    • Griffiths HR (2005) ROS as signalling molecules in T cells-evidence for abnormal redox signalling in the autoimmune disease, rheumatoid arthritis. Redox Rep 10:273-280
    • (2005) Redox Rep , vol.10 , pp. 273-280
    • Griffiths, H.R.1
  • 17
    • 26444582959 scopus 로고    scopus 로고
    • Soy isoflavone glycitein protects against beta amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans.
    • Gutierrez-Zepeda A, Santell R, Wu Z, Brown M, Wu Y, Khan I, Link CD, Zhao B, Luo Y (2005) Soy isoflavone glycitein protects against beta amyloid-induced toxicity and oxidative stress in transgenic Caenorhabditis elegans. BMC Neurosci 6:54
    • (2005) BMC Neurosci , vol.6 , pp. 54
    • Gutierrez-Zepeda, A.1    Santell, R.2    Wu, Z.3    Brown, M.4    Wu, Y.5    Khan, I.6    Link, C.D.7    Zhao, B.8    Luo, Y.9
  • 18
    • 0034079862 scopus 로고    scopus 로고
    • Free radicals and antioxidants in the year 2000. a historical look to the future
    • Gutteridge JM, Halliwell B (2000) Free radicals and antioxidants in the year 2000. A historical look to the future. Ann NY Acad Sci 899:136-147
    • (2000) Ann NY Acad Sci , vol.899 , pp. 136-147
    • Gutteridge, J.M.1    Halliwell, B.2
  • 20
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman D (1957) Aging: a theory based on free radical and radiation chemistry. J Gerontol 2:298-300
    • (1957) J Gerontol , vol.2 , pp. 298-300
    • Harman, D.1
  • 21
    • 0035846604 scopus 로고    scopus 로고
    • Daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
    • Henderson ST, Johnson TE (2001) daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr Biol 11:1975-1980
    • (2001) Curr Biol , vol.11 , pp. 1975-1980
    • Henderson, S.T.1    Johnson, T.E.2
  • 22
    • 33646901265 scopus 로고    scopus 로고
    • Daf-16 protects the nematode Caenorhabditis elegans during food deprivation
    • Henderson ST, Bonafe M, Johnson TE (2006) daf-16 protects the nematode Caenorhabditis elegans during food deprivation. J Gerontol A Biol Sci Med Sci 61:444-460
    • (2006) J Gerontol a Biol Sci Med Sci , vol.61 , pp. 444-460
    • Henderson, S.T.1    Bonafe, M.2    Johnson, T.E.3
  • 24
    • 33745223646 scopus 로고    scopus 로고
    • Finding function in novel targets: C. elegans as a model organism.
    • Kaletta T, Hengartner MO (2006) Finding function in novel targets: C. elegans as a model organism. Nat Rev Drug Discov 5:387-399
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 387-399
    • Kaletta, T.1    Hengartner, M.O.2
  • 25
    • 33846586683 scopus 로고    scopus 로고
    • The Ginkgo biloba extract EGb761 reduces stress sensitivity, ROS accumulation and expression of catalase and glutathione S-transferase 4 in Caenorhabditis elegans
    • Kampkotter A, Pielarski T, Rohrig R, Timpel C, Chovolou Y, Watjen W, Kahl R (2007a) The Ginkgo biloba extract EGb761 reduces stress sensitivity, ROS accumulation and expression of catalase and glutathione S-transferase 4 in Caenorhabditis elegans. Pharmacol Res 55:139-147
    • (2007) Pharmacol Res , vol.55 , pp. 139-147
    • Kampkotter, A.1    Pielarski, T.2    Rohrig, R.3    Timpel, C.4    Chovolou, Y.5    Watjen, W.6    Kahl, R.7
  • 26
    • 34047152197 scopus 로고    scopus 로고
    • Investigations of protective effects of the flavonoids quercetin and rutin on stress resistance in the model organism Caenorhabditis elegans
    • Kampkotter A, Gombitang-Nkwonkam C, Zurawski RF, Timpel C, Chovolou Y, Watjen W, Kahl R (2007b) Investigations of protective effects of the flavonoids quercetin and rutin on stress resistance in the model organism Caenorhabditis elegans. Toxicology 234:113-123
    • (2007) Toxicology , vol.234 , pp. 113-123
    • Kampkotter, A.1    Gombitang-Nkwonkam, C.2    Zurawski, R.F.3    Timpel, C.4    Chovolou, Y.5    Watjen, W.6    Kahl, R.7
  • 27
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: Insights from long-lived mutants
    • Kenyon C (2005) The plasticity of aging: insights from long-lived mutants. Cell 120:449-460
    • (2005) Cell , vol.120 , pp. 449-460
    • Kenyon, C.1
  • 28
    • 0035025124 scopus 로고    scopus 로고
    • Mechanisms of carcinogenesis: Focus on oxidative stress and electron transfer
    • Kovacic P, Jacintho JD (2001) Mechanisms of carcinogenesis: focus on oxidative stress and electron transfer. Curr Med Chem 8:773-796
    • (2001) Curr Med Chem , vol.8 , pp. 773-796
    • Kovacic, P.1    Jacintho, J.D.2
  • 32
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • Middleton E Jr, Kandaswami C, Theoharides TC (2000) The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev 52:673-751
    • (2000) Pharmacol Rev , vol.52 , pp. 673-751
    • Middleton Jr., E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 35
    • 0031808308 scopus 로고    scopus 로고
    • Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes
    • Noroozi M, Angerson WJ, Lean ME (1998) Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes. Am J Clin Nutr 67:1210-1218
    • (1998) Am J Clin Nutr , vol.67 , pp. 1210-1218
    • Noroozi, M.1    Angerson, W.J.2    Lean, M.E.3
  • 36
    • 15444371989 scopus 로고    scopus 로고
    • JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
    • Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ, Tissenbaum HA (2005) JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. Proc Natl Acad Sci USA 102:4494-4499
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4494-4499
    • Oh, S.W.1    Mukhopadhyay, A.2    Svrzikapa, N.3    Jiang, F.4    Davis, R.J.5    Tissenbaum, H.A.6
  • 37
    • 31744438846 scopus 로고    scopus 로고
    • Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation
    • Oh SW, Mukhopadhyay A, Dixit BL, Raha T, Green MR, Tissenbaum HA (2006) Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation. Nat Genet 38:251-257
    • (2006) Nat Genet , vol.38 , pp. 251-257
    • Oh, S.W.1    Mukhopadhyay, A.2    Dixit, B.L.3    Raha, T.4    Green, M.R.5    Tissenbaum, H.A.6
  • 38
    • 0041196069 scopus 로고    scopus 로고
    • Metalloporphyrin class of therapeutic catalytic antioxidants
    • Patel M, Day BJ (1999) Metalloporphyrin class of therapeutic catalytic antioxidants. Trends Pharmacol Sci 20:359-364
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 359-364
    • Patel, M.1    Day, B.J.2
  • 39
    • 33745114656 scopus 로고    scopus 로고
    • Recent aging research in Caenorhabditis elegans
    • Schaffitzel E, Hertweck M (2006) Recent aging research in Caenorhabditis elegans. Exp Gerontol 41:557-563
    • (2006) Exp Gerontol , vol.41 , pp. 557-563
    • Schaffitzel, E.1    Hertweck, M.2
  • 40
    • 33747819235 scopus 로고    scopus 로고
    • Crucial role of interferon-gamma and stimulated macrophages in cardiovascular disease
    • Schroecksnadel K, Frick B, Winkler C, Fuchs D (2006) Crucial role of interferon-gamma and stimulated macrophages in cardiovascular disease. Curr Vasc Pharmacol 4:205-213
    • (2006) Curr Vasc Pharmacol , vol.4 , pp. 205-213
    • Schroecksnadel, K.1    Frick, B.2    Winkler, C.3    Fuchs, D.4
  • 41
    • 0242467845 scopus 로고    scopus 로고
    • Elevation of oxidative free radicals in Alzheimer's disease models can be attenuated by Ginkgo biloba extract EGb 761
    • Smith JV, Luo Y (2003) Elevation of oxidative free radicals in Alzheimer's disease models can be attenuated by Ginkgo biloba extract EGb 761. J Alzheimers Dis 5:287-300
    • (2003) J Alzheimers Dis , vol.5 , pp. 287-300
    • Smith, J.V.1    Luo, Y.2
  • 42
    • 2542467819 scopus 로고    scopus 로고
    • Studies on molecular mechanisms of Ginkgo biloba extract.
    • Smith JV, Luo Y (2004) Studies on molecular mechanisms of Ginkgo biloba extract. Appl Microbiol Biotechnol 64:465-472
    • (2004) Appl Microbiol Biotechnol , vol.64 , pp. 465-472
    • Smith, J.V.1    Luo, Y.2
  • 43
    • 0032509302 scopus 로고    scopus 로고
    • Genome sequence of the nematode C. elegans: A platform for investigating biology
    • The C. elegans Sequencing Consortium
    • The C. elegans Sequencing Consortium (1998) Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282:2012-2018
    • (1998) Science , vol.282 , pp. 2012-2018
  • 44
  • 45


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