The cyclin-dependent kinase inhibitors, cki-1 and cki-2, act in overlapping but distinct pathways to control cell cycle quiescence during C. elegans development

Cell Cycle

Volumn 8, Issue 16, 2009, Pages 2613-2620

  Buck, Sarah H ^a   Chiu, Daniel ^a   Saito, R Mako ^a,b  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b NORRIS COTTON CANCER CENTER   (United States)

Author keywords

C. elegans; Cell cycle quiescence; Cyclin dependent kinase inhibitor; Vulva development

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2; CYCLIN E; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL DIVISION; CONTROLLED STUDY; GENE INTERACTION; GENE MUTATION; GENETIC SCREENING; NONHUMAN; PARASITE DEVELOPMENT; PHENOTYPE; RNA INTERFERENCE;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 69249219215     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.16.9354     Document Type: Article

References (41)

1. Pardee AB. A restriction point for control of normal animal cell proliferation. Proc Natl Acad Sci USA 1974; 71:1286-1290
2. Temin HM. Stimulation by serum of multiplication of stationary chicken cells. J Cell Physiol 1971; 78:161-170
3. 1 regulation and checkpoints operating around START in fission yeast. Bioessays 1995; 17:481-490
4. Whyte P, Buchkovich KJ, Horowitz JM, Friend SH, Raybuck M, Weinberg RA, et al. Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 1988; 334:124-129 (Pubitemid 18165107)
5. DeCaprio JA, Ludlow JW, Figge J, Shew JY, Huang CM, Lee WH, et al. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 1988; 54:275-283 (Pubitemid 18188759)
6. Dyson N, Howley PM, Munger K, Harlow E. The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 1989; 243:934-937 (Pubitemid 19066153)
7. Friend SH, Horowitz JM, Gerber MR, Wang XF, Bogenmann E, Li FP, et al. Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein. Proc Natl Acad Sci USA 1987; 84:9059-9063
8. Harbour JW, Lai SL, Whang-Peng J, Gazdar AF, Minna JD, Kaye FJ. Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 1988; 241:353-357 (Pubitemid 18189355)
9. Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev 1998; 12:2245-2262
10. 1-phase progression. Genes Dev 1999; 13:1501-1512
11. Euling S, Ambros V. Heterochronic genes control cell cycle progress and developmental competence of C. elegans vulva precursor cells. Cell 1996; 84:667-676
12. Sulston JE, Horvitz HR. Post-embryonic cell lineages of the nematode, Caenorhabditis elegans. Dev Biol 1977; 56:110-156
13. Greenwald IS, Sternberg PW, Horvitz HR. The lin-12 locus specifies cell fates in Caenorhabditis elegans. Cell 1983; 34:435-444
14. Clayton JE, van den Heuvel SJ, Saito RM. Transcriptional control of cell cycle quiescence during C. elegans development. Dev Biol 2008; 313:603-613
15. Saito RM, Perreault A, Peach B, Satterlee JS, van den Heuvel S. The CDC-14 phosphatase controls developmental cell cycle arrest in C. elegans. Nat Cell Biol 2004; 6:777-783 (Pubitemid 39144484)
16. Hong Y, Roy R, Ambros V. Developmental regulation of a cyclin-dependent kinase inhibitor controls postembryonic cell cycle progression in Caenorhabditis elegans. Development 1998; 125:3585-3597 (Pubitemid 28469959)
17. Fukuyama M, Gendreau SB, Derry WB, Rothman JH. Essential embryonic roles of the CKI-1 cyclin-dependent kinase inhibitor in cell cycle exit and morphogenesis in C. elegans. Dev Biol 2003; 260:273-286 (Pubitemid 36900349)
18. 1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans. Nat Cell Biol 1999; 1:486-492
19. O'Connell KF, Leys CM, White JG. A genetic screen for temperature-sensitive celldivision mutants of Caenorhabditis elegans. Genetics 1998; 149:1303-1321
20. 1 progression in C. elegans. Development 2001; 128:4349-4359
21. Fay DS, Han M. Mutations in cye-1, a Caenorhabditis elegans cyclin E homolog, reveal coordination between cell cycle control and vulval development. Development 2000; 127:4049-4060
22. Lu X, Horvitz HR. lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48. Cell 1998; 95:981-991
23. Sigurdson DC, Spanier GJ, Herman RK. Caenorhabditis elegans deficiency mapping. Genetics 1984; 108:331-345
24. Fay DS, Keenan S, Han M. fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen. Genes Dev 2002; 16:503-517
25. Captan VV, Goszczynski B, McGhee JD. Neither maternal nor zygotic med-1/med-2 genes play a major role in specifying the Caenorhabditis elegans endoderm. Genetics 2007; 175:969-974
26. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391:806-811
27. Ahringer J. Reverse Genetics. In: The C. elegans Research Community, ed. WormBook, 2006.
28. Kim DY, Roy R. Cell cycle regulators control centrosome elimination during oogenesis in Caenorhabditis elegans. J Cell Biol 2006; 174:751-757
29. Susaki E, Nakayama K, Yamasaki L, Nakayama KI. Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model. Proc Natl Acad Sci USA 2009; 106:5192-5197
30. Robert VJ, Bessereau JL. Manipulating the Caenorhabditis elegans genome using mariner transposons. Genetica 2009.
31. Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974; 77:71-94.
32. Simmer F, Moorman C, van der Linden AM, Kuijk E, van den Berghe PVE, Kamath RS, et al. Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. PLoS Biol 2003; 1:12.
33. Simmer F, Tijsterman M, Parrish S, Koushika SP, Nonet ML, Fire A, et al. Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi. Curr Biol 2002; 12:1317-1319
34. Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, Gotta M, et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 2003; 421:231-237
35. Rual JF, Ceron J, Koreth J, Hao T, Nicot AS, Hirozane-Kishikawa T, et al. Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res 2004; 14:2162-2168
36. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25:402-408 (Pubitemid 34164012)
37. Abrahante JE, Daul AL, Li M, Volk ML, Tennessen JM, Miller EA, et al. The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev Cell 2003; 4:625-637
38. Blelloch R, Anna-Arriola SS, Gao D, Li Y, Hodgkin J, Kimble J. The gon-1 gene is required for gonadal morphogenesis in Caenorhabditis elegans. Dev Biol 1999; 216:382-393
39. Corsi AK, Kostas SA, Fire A, Krause M. Caenorhabditis elegans twist plays an essential role in non-striated muscle development. Development 2000; 127:2041-2051
40. Fukushige T, Hawkins MG, McGhee JD. The GATA-factor elt-2 is essential for formation of the Caenorhabditis elegans intestine. Dev Biol 1998; 198:286-302.
41. Duerr JS. Immunohistochemistry. In: The C. elegans Research Community, ed. WormBook 2006.