Assessment of stress-related gene expression in the heavy metal-exposed nematode Caenorhabditis elegans: A potential biomarker for metal-induced toxicity monitoring and environmental risk assessment

Environmental Toxicology and Chemistry

Volumn 25, Issue 11, 2006, Pages 2946-2956

  Roh, Ji Yeon ^a   Lee, Junho ^b   Choi, Jinhee ^a  

^a University of Seoul   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Biomarker; Caenorhabditis elegans; Environmental risk assessment; Metal toxicity monitoring; Stress related gene expression

Indexed keywords

BIOMARKERS; BIOSENSORS; CADMIUM; CONTAMINATION; LEAD; RISK ASSESSMENT; TOXICITY;

CAENORHABDITIS ELEGANS; ENVIRONMENTAL RISK ASSESSMENT; GREEN FLUORESCENT PROTEIN TRANSGENIC NEMATODES; METAL TOXICITY MONITORING;

GENETIC ENGINEERING;

ARSENIC TRIOXIDE; BIOLOGICAL MARKER; CADMIUM; CATALASE; CHROMIUM; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME P450; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEIN; HEAT SHOCK PROTEIN 70; HEAVY METAL; LEAD; METALLOTHIONEIN II; PROTEIN P53;

BIOMARKER; ENVIRONMENTAL MONITORING; ENVIRONMENTAL RISK; GENE EXPRESSION; HEAVY METAL; NEMATODE; POLLUTION EXPOSURE; RISK ASSESSMENT; TOXICITY;

ARTICLE; BIOSENSOR; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENHANCER REGION; ENVIRONMENTAL MONITORING; GENE EXPRESSION; GROWTH; HEAVY METAL POISONING; NONHUMAN; PRIORITY JOURNAL; REPRODUCTION; RISK ASSESSMENT; STRESS; TOXICITY; TRANSGENIC ORGANISM;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ARSENITES; BIOLOGICAL MARKERS; CAENORHABDITIS ELEGANS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HELMINTH PROTEINS; LETHAL DOSE 50; METALS, HEAVY; REPRODUCTION; RISK ASSESSMENT; RNA, MESSENGER; SOIL POLLUTANTS; STRESS;

CAENORHABDITIS ELEGANS;

EID: 33846124929     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/05-676R.1     Document Type: Article

References (32)

1. Peredney CL, Williams PL. 2000. Utility of Caenorhabditis elegans for assessing heavy metal contamination in artificial soil. Arch Environ Contam Toxicol 39:113-118.
2. Willams PL, Anderson GL, Johnstone JL, Nunn AD, Tweedle MF, Wedeking P. 2000. Caenorhabditis elegans as an alternative animal species. J Toxicol Environ Health A 61:641-647.
3. Boyd WA, Williams PL. 2003. Availability of metals to the nematode Caenorhabditis elegans: Toxicity based on total concentrations in soil and extracted fractions. Environ Toxicol Chem 22: 1100-1106.
4. Menzel R, Rodel M, Kulas J, Steinberg CE. 2005. CYP35: Xenobiotically induced gene expression in the nematode Caenorhabditis elegans. Arch Biochem Biophys 438:93-102.
5. Reichert K, Menzel R. 2005. Expression profiling of five different xenobiotics using a Caenorhabditis elegans whole-genome microarray. Chemosphere 61:229-237.
6. Dhawan R, Dusenbery DB, Williams PL. 1999. Comparison of lethality, reproduction, and behavior as lexicological endpoints in the nematode Caenorhabditis elegans. J Toxicol Environ Health A 58:451-462.
7. Anderson GL, Boyd WA, Williams PL. 2001. Assessment of sublethal endpoints for toxicity testing with the nematode Caenorhabditis elegans. Environ Toxicol Chem 20:833-838.
8. Boyd WA, Williams PL. 2003. Comparison of the sensitivity of three nematode species to cooper and their utility in aquatic and soil toxicity tests. Environ Toxicol Chem 22:2768-2774.
9. Brenner S. 1974. The genetics of Caenorhabditis elegans. Genetics 77:71-94.
10. Williams PL, Dusenbery DB. 1990. Aquatic toxicity testing using the nematode Caenorhabditis elegans. Environ Toxicol Chem 9: 1285-1290.
11. Hong M, Kwon JY, Shim J, Lee J. 2004. Differential hypoxia response of hsp-16 genes in the nematode. J Mol Biol 344:369-381.
12. Dhawan R, Dusenbery DB, Williams PL. 2000. A comparison of metal-induced lethality and behavioral responses in the nematode Caenorhabditis elegans. Environ Toxicol Chem 19:3061-3067.
13. Ura K, Kai T, Sakata S, Iguchi T, Arizono K. 2002. Aquatic acute toxicity testing using the nematode Caenorhabditis elegans. J Health Sci 48:583-586.
14. Cressman CP III, Williams PL. 1997. Reference toxicants for toxicity testing using Caenorhabditis elegans in aquatic media. In Dwyer FJ, Doane TR, Hinman TR, eds, Environmental Toxicology and Risk Assessment: Modeling and Risk Assessment, Vol 6. STP 1317. American Society for Testing and Materials, Philadelphia, PA, pp 518-532.
15. Liao VH, Dong J, Freedman JH. 2002. Molecular characterization of a novel, cadmium-inducible gene from the nematode Caenorhabditis elegans. J Biol Chem 277:42049-42059.
16. Dong J, Song MO, Freedman JH. 2005. Identification and characterization of a family of Caenorhabditis elegans genes that is homologous to the cadmium-responsive gene cdr-1. Biochim Biophys Acta 1727:16-26.
17. Menzel R, Bogaert T, Achazi R. 2001. A systematic gene expression screen of Caenorhabditis elegans cytochrome P450 genes reveals CYP35 as strongly xenobiotic inducible. Arch Biochem Biophys 395:158-168.
18. Kohra S, Kuwahara K, Takao Y, Ishibashi Y, Lee HC, Arizono K, Tominaga N. 2002. Effect of bisphenol A on the feeding behavior of Caenorhabditis elegans. J Health Sci 48:93-95.
19. Tominaga N, Kohra S, Iguchi T, Arizono K. 2003. A multigeneration sublethal assay of phenols using the nematode Caenorhabditis elegans. J Health Sci 49:459-463.
20. Anderson GL, Cole RD, Williams PL. 2004. Assessing behavioral toxicity with Caenorhabditis elegans. Environ Toxicol Chem 23: 1235-1240.
21. Carvan MJ III, Dalton TP, Stuart GW, Nebert DW. 2000. Transgenic zebrafish as sentinels for aquatic pollution. Ann N Y Acad Sci 919:133-147.
22. Blechinger SR, Warren JT Jr, Kuwada JY, Krone PH. 2002. Developmental toxicology of cadmium in living embryos of a stable transgenic zebrafish line. Environ Health Perspect 110:1041-1046.
23. Kurauchi K, Nakaguchi Y, Tsutsumi M, Hori H, Kurihara R, Hashimoto S, Ohnuma R, Yamamoto Y, Matsuoka S, Kawai S, Hirata T, Kinoshita M. 2005. In vivo visual reporter system for detection of estrogen-like substances by transgenic medaka. Environ Sci Technol 39:2762-2768.
24. Scholz S, Kurauchi K, Kinoshita M, Oshima Y, Ozato K, Schirmer K, Wakamatsu Y. 2005. Analysis of estrogenic effects by quantification of green fluorescent protein in juvenile fish of a transgenic medaka. Environ Toxicol Chem 24:2553-2561.
25. Stringham EG, Candido EP. 1994. Transgenic hsp16-lacZ strains of the soil nematode Caenorhabditis elegans as biological monitors of environmental stress. Environ Toxicol Chem 13:1211-1220.
26. Jones D, Stringham EG, Babich SL, Candido EP. 1996. Transgenic strains of the nematode C. elegans in biomonitoring and toxicology: Effects of captan and related compounds on the stress response. Toxicology 109:119-127.
27. Chu KW, Chan SK, Chow KL. 2005. Improvement of heavy metal stress and toxicity assays by coupling a transgenic reporter in a mutant nematode strain. Aquat Toxicol 74:320-332.
28. Roesijadi G. 1994. Metallothionein induction as a measure of response to metal exposure in aquatic animal. Environ Health Perspect 12:91-95.
29. Yoshimi T, Minowa K, Karouna-Renier NK, Watanabe C, Sugaya Y, Miura T. 2002. Activation of stress-induced gene by insecticides in the midge, Chironomus yoshimatsui. J Biochem Mol Toxicol 16:10-17.
30. Kwon JY, Hong M, Choi MS, Kans S, Duke K, Kim S, Lee S, Lee J. 2004. Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans. Genomics 83:600-614.
31. Barsyte D, Lovejoy DA, Lithgow GJ. 2001. Longevity and heavy metal resistance in daf-2 and age-1 long-lived mutants of Caenorhabditis elegans. FASEB J 15:627-634.
32. Swain SC, Keusekotten K, Baumeister R, Sturzebaum SR. 2004. C. elegans metallothioneins: New insights into the phenotypic effects of cadmium toxicosis. J Mol Biol 341:951-959.