Role of nitric oxide and prostaglandins in mechanically induced bone formation

Journal of Bone and Mineral Research

Volumn 13, Issue 6, 1998, Pages 1039-1044

  Chow, J W M ^a   Fox, S W ^a   Lean, J M ^a   Chambers, T J ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; HYDRALAZINE; INDOMETACIN; MESSENGER RNA; N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; PROSTAGLANDIN; S NITROSOGLUTATHIONE;

ANIMAL EXPERIMENT; ARTICLE; BONE DEVELOPMENT; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; MECHANICAL STIMULATION; MORPHOMETRICS; NONHUMAN; ONCOGENE C FOS; OSSIFICATION; RAT; VERTEBRA; WEIGHT BEARING;

ANIMALS; BLOTTING, NORTHERN; BONE DEVELOPMENT; COCCYX; CYCLOOXYGENASE INHIBITORS; ENZYME INHIBITORS; FEMALE; GENES, FOS; GLUTATHIONE; HYDRALAZINE; INDOMETHACIN; NITRIC OXIDE; NITROSO COMPOUNDS; OMEGA-N-METHYLARGININE; PENICILLAMINE; PROSTAGLANDINS; RATS; RATS, WISTAR; RNA, MESSENGER; S-NITROSO-N-ACETYLPENICILLAMINE; S-NITROSOGLUTATHIONE; VASODILATOR AGENTS; WEIGHT-BEARING;

EID: 0031779953     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1998.13.6.1039     Document Type: Article

References (38)

1. Chow JWM, Chambers TJ 1994 Indomethacin has distinct early and late actions on bone formation induced by mechanical stimulation. Am J Physiol 267:E287-E292.
2. Pead MJ, Lanyon LE 1989 Indomethacin modulation of load-related stimulation of new bone formation in vivo. Calcif Tissue Int 45:34-40.
3. Forwood MR 1996 Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. J Bone Miner Res 11:1688-1693.
4. Fox SW, Chambers TJ, Chow JWM 1996 Nitric oxide is an early mediator of the increase in bone formation by mechanical stimulation. Am J Physiol 270:E955-E960.
5. Turner CH, Takano Y, Owan I, Murrell GA 1996 Nitric oxide inhibitor L-NAME suppresses mechanically induced bone formation in rats. Am J Physiol 270:E634-E639.
6. El Haj AJ, Minter SL, Rawlinson SCF, Suswillo R, Lanyon LE 1990 Cellular responses to mechanical loading in vitro. J Bone Miner Res 5:923-932.
7. Lean JM, Jagger CJ, Chambers TJ, Chow JWM 1995 Increased insulin-like growth factor I mRNA expression in rat osteocytes in response to mechanical stimulation. Am J Physiol 268: E318-E327.
8. Lean JM, Mackay AG, Chow JWM, Chambers TJ 1996 Osteocytic expression of mRNA for c-fos and IGF-I: An immediate early gene response to an osteogenic stimulus. Am J Physiol 270:E937-E945.
9. Chow JWM, Jagger CJ, Chambers TJ 1993 Characterization of osteogenic response to mechanical stimulation in cancellous bone of rat caudal vertebrae. Am J Physiol 265:E340-E347.
10. Chambers TJ, Evans M, Gardner TN, Turner-Smith A, Chow JWM 1993 Induction of bone formation in rat tail vertebrae by mechanical loading. Bone Miner 20:167-178.
11. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium-thiocynate-phenol-chloroform extraction. Anal Biochem 162:156-159.
12. Sambrook J, Fritsch EF, Maniatis T 1989 Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, NY, U.S.A.
13. Curran T, Gordon MB, Rubino KL, Sambucetti LC 1987 Isolation and characterization of the c-fos (rat) cDNA and analysis of post-translational modification in vitro. Oncogene 2:79-84.
14. Cleveland DW, Lopata MA, MacDonald RJ, Cowan NJ, Rutter WJ, Kirschner MW 1980 Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes. Cell 20:95-105.
15. Thompson KE, Friberg P, Adams MA 1992 Vasodilators inhibit acute α1-adrenergic receptor-induced trophic responses in the vasculature. Hypertension 20:809-815.
16. G, dimethyl-1-arginine and their reversibility by vasodilators in conscious rats. Br J Pharmacol 110:1457-1464.
17. Skerry TM, Bitensky L, Chayen J, Lanyon LE 1989 Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo. J Bone Miner Res 4:783-788.
18. Pitsillides AA, Rawlinson SCF, Suswillo RFL, Bourrin S, Zaman G, Lanyon LE 1995 Mechanical strain induced NO production by bone cells: A possible role in adaptative bone (re)modelling? FASEB J 9:1614-1622.
19. Panzenbeck MJ, Baez A, Kaley G 1984 Nitroglycerin and nitroprusside increase coronary blood flow in dogs by a mechanism independent of prostaglandin release. Am J Cardiol 53:936-940.
20. de Caterina R, Dorso CR, Tack-Goldman K, Weksler BB 1985 Nitrates and endothelial prostacyclin production: Studies in vitro. Circulation 71:176-182.
21. Förstermann U, Neufang B 1984 The endothelium-dependent vasodilator effect of acetylcholine: Characterization of the endothelial relaxing factor with inhibitors of arachidonic acid metabolism. Eur J Pharmacol 103:65-70.
22. Feigen LP, Chapnick BM, Felmming JE, Kadowitz PJ 1978 Prostaglandins: Renal vascular responses to bradykinin, histamine, and nitroglycerine. Am J Physiol 234:H496-H502.
23. Morcillo E 1980 Responses to arachidonic acid and other dilator agonists and their modification by inhibition of prostaglanding synthesis in the canine hindlimb. J Pharm Pharmacol 32:340-343.
24. Salvemini D, Misko TP, Masferrer JL, Seibert K, Currie MG, Needleman P 1993 Nitric oxide activates cyclooxygenase en-zymes. Proc Natl Acad Sci USA 90:7240-7244.
25. Rettori V, Belova N, Dees WL, Nyberg CL, Gimeno M, McCann SM 1993 Role of nitric oxide in the control of luteinizing hormone-releasing hormone release in vivo and in vitro. Proc Natl Acad Sci USA 90:10130-10134.
26. Corbett JA, Kwon G, Turk J, McDaniel ML 1993 IL-1b induces the coexpression of both nitric oxide synthase and cyclooxygenase by Islets of Langerhans: Activation of cyclooxygenase by nitric oxide. Biochemistry 32:13767-13770.
27. Salvemini D, Seibert K, Masferrer JL, Misko TP, Currie MG, Needleman P 1994 Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation. J Clin Invest 93:1940-1947.
28. Salvemini D, Settle SL, Masferrer JL, Seibert K, Currie MG, Needleman P 1995 Regulation of prostaglandin production by nitric oxide: An in vivo analysis. Br J Pharmacol 114:1171-1178.
29. Inoue T, Fukuo K, Morimoto S, Koh E, Ogihara T 1993 Nitric oxide mediates interleukin-1-induced prostaglandin E, production by vascular smooth muscle cells. Biochem Biophys Res Commun 194:420-424.
30. Abate C, Patel L, Rauscher FJ III, Curran T 1990 Redox regulation of fos and jun DNA-binding activity in vitro. Science 249:1157-1161.
31. Pilz RB, Suhasini M, Idriss S, Meinkoth JL, Boss GR 1995 Nitric oxide and cGMP analogs activate transcription from AP-1-responsive promoters in mammalian cells. FASEB J 9:552-558.
32. Peunova N, Enikolopov G 1993 Amplification of calcium-induced gene transcription by nitric oxide in neuronal cells. Nature 364:450-453.
33. Velluci SV, Parrott RF 1995 Prostaglandin-dependent c-Fos expression in the median preoptic nucleus of pigs subjected to restraint: Correlation with hyperthermia. Neurosci Lett 198: 49-51.
34. Niimi M, Sato M, Wada Y, Takahara J, Kawanishi K 1996 Effect of central and continuous intravenous injection of interleukin-1 beta on brain c-fos expression in the rat: involvement of prostaglandins. Neuroimmunomodulation 3:87-92.
35. Klein-Nulend J, Semeins CM, Ajubi NE, Nijweide PJ, Burger EH 1995 Pulsating fluid flow increases nitric oxide (NO) synthesis by osteocytes but not periosteal fibroblasts - Correlation with prostaglandin upregulation. Biochem Biophys Res Commun 217:640-648.
36. Jee WSS, Ma YF 1997 The in vivo anabolic actions of prostaglandins in bone. Bone 21:293-304.
37. 2 increases the skeletal response to mechanical loading. J Bone Miner Res 12:276-282.
38. 2 prevents disuse-induced cortical bone loss. Bone 13:153-159.